Glutathione Peroxidase

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  Subject Areas on Research

  • A comparison of glutathione-dependent enzymes in liver, gills and posterior kidney of channel catfish (Ictalurus punctatus). 
  • A comprehensive evaluation of the enzymatic and nonenzymatic antioxidant systems in childhood asthma. 
  • Adaptation to hyperoxia in the neonatal rat: kinetic parameters of the oxygen-mediated induction of lung superoxide dismutases, catalase and glutathione peroxidase. 
  • Altered oxidative metabolism in selenium-deficient rat granulocytes. 
  • An age-related difference in hyperoxia lethality: role of lung antioxidant defense mechanisms. 
  • Antihuman plasma glutathione peroxidase antibodies: immunologic investigations to determine plasma glutathione peroxidase protein and selenium content in plasma. 
  • Antioxidant defense mechanisms in cultured pleural mesothelial cells. 
  • Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan. 
  • Antioxidant responses and oxidative stress in sheepshead minnow larvae exposed to Corexit 9500® or its component surfactant, DOSS. 
  • Antioxidative defense enzymes in placenta protect placenta and fetus in inherited thrombophilia from hydrogen peroxide. 
  • Antioxidative system in the erythrocytes of preterm neonates with sepsis: the effects of vitamin E supplementation. 
  • Arctigenin Attenuates Ischemia/Reperfusion Induced Ventricular Arrhythmias by Decreasing Oxidative Stress in Rats. 
  • Aspirin-induced hemolysis: the role of concomitant oxidant (H2O2) challenge. 
  • C-phycocyanin modulates selenite-induced cataractogenesis in rats. 
  • Chronic ethanol treatment induces H2O2 production selectively in pericentral regions of the liver lobule. 
  • Comparative analysis of antioxidative systems in malignant and benign brain tumours. 
  • Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects. 
  • DIO2 modifies inflammatory responses in chondrocytes. 
  • Developmental expression of extracellular glutathione peroxidase suggests antioxidant roles in deciduum, visceral yolk sac, and skin. 
  • Differences in direct pharmacologic effects and antioxidative properties of mature breast milk and infant formulas. 
  • Disorders of respiratory burst termination. 
  • Evolution of budding yeast prion-determinant sequences across diverse fungi. 
  • Expression of extracellular glutathione peroxidase in human and mouse gastrointestinal tract. 
  • Extracellular glutathione peroxidase (Gpx3) binds specifically to basement membranes of mouse renal cortex tubule cells. 
  • Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells. 
  • Extracellular glutathione peroxidase is secreted basolaterally by human renal proximal tubule cells. 
  • Extracellular glutathione peroxidase mRNA and protein in human cell lines. 
  • Generation of hydrogen peroxide and failure of antioxidative responses in pancreatic islets of male C57BL/6 mice are associated with diabetes induced by multiple low doses of streptozotocin. 
  • Glutathione and zebrafish: Old assays to address a current issue. 
  • Glutathione peroxidase and selenium deficiency in patients receiving home parenteral nutrition: time course for development of deficiency and repletion of enzyme activity in plasma and blood cells. 
  • Glutathione peroxidase of calf trabecular meshwork. 
  • Glutathione peroxidase protein. Absence in selenium deficiency states and correlation with enzymatic activity. 
  • Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo. 
  • Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A. 
  • Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure. 
  • Human kidney proximal tubules are the main source of plasma glutathione peroxidase. 
  • Human placenta makes extracellular glutathione peroxidase and secretes it into maternal circulation. 
  • Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis. 
  • Improving feature detection and analysis of surface-enhanced laser desorption/ionization-time of flight mass spectra. 
  • Increase in extracellular glutatione peroxidase in plasma and lungs of mice exposed to hyperoxia. 
  • Increased expression of extracellular glutathione peroxidase in mice with dextran sodium sulfate-induced experimental colitis. 
  • Increased sensitivity to H2O2 in glutathione peroxidase-deficient rat granulocytes. 
  • Induction of oxidative cell damage by photo-treatment with zinc meta N-methylpyridylporphyrin. 
  • Intracellular reduction of selenite into glutathione peroxidase. Evidence for involvement of NADPH and not glutathione as the reductant. 
  • Maturation of the antioxidant system and the effects on preterm birth. 
  • Mitochondrial adaptations to obesity-related oxidant stress. 
  • Molecular and biochemical aspects of selenium metabolism and deficiency. 
  • Oxidant, mixed-function oxidase and peroxisomal responses in channel catfish exposed to a bleached kraft mill effluent. 
  • Oxidants, antioxidants and the ischemic brain. 
  • Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories. 
  • Partial sequence of human plasma glutathione peroxidase and immunologic identification of milk glutathione peroxidase as the plasma enzyme. 
  • Plasma glutathione peroxidase and its relationship to renal proximal tubule function. 
  • Plasma selenium-dependent glutathione peroxidase. Cell of origin and secretion. 
  • Protection from oxidation enhances the survival of cultured mesencephalic neurons. 
  • Proximal muscle weakness and selenium deficiency associated with long term parenteral nutrition. 
  • Pulmonary and hepatic glutathione levels, glutathione shuttle enzymes and lipid peroxidation in rats exposed intratracheally to coal fly ash. 
  • Purification and characterization of human plasma glutathione peroxidase: a selenoglycoprotein distinct from the known cellular enzyme. 
  • Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells. 
  • Reversal of biochemical and functional abnormalities in erythrocytes secondary to selenium deficiency. 
  • Role of antioxidant enzymes in the induction of increased experimental metastasis by hydroxyurea. 
  • Selenium deficiency with total parenteral nutrition: reversal of biochemical and functional abnormalities by selenium supplementation: a case report. 
  • Selenium repletion and glutathione peroxidase--differential effects on plasma and red blood cell enzyme activity. 
  • Selenium-dependent glutathione peroxidase protein and activity: immunological investigations on cellular and plasma enzymes. 
  • Transcriptional regulation of crystallin, redox, and apoptotic genes by C-Phycocyanin in the selenite-induced cataractogenic rat model. 
  • Tyloxapol confers durable protection against hyperoxic lung injury in the rat. 
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  Keywords of People

  • Hoffman, Maureane, Professor of Pathology, Immunology
  • Warner, David Samuel, Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology