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Subject Areas on Research
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A comprehensive testing algorithm for the diagnosis of Fabry disease in males and females.
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A new ganglioside of the lactotetraose series, GalNAc-3'-isoLM1, detected in human meconium.
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A phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: cancer and leukemia group B study 89903.
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A predicted geranylgeranyl reductase reduces the ω-position isoprene of dolichol phosphate in the halophilic archaeon, Haloferax volcanii.
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Accumulation of glycolipids containing N-acetylglucosamine in erythrocyte stroma of patients with congenital dyserythropoietic anemia type II (HEMPAS).
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An ethanolamine-phosphate modified glycolipid in Clostridium acetobutylicum that responds to membrane stress.
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Assignment of the 1H, 13C and 15N resonances of the LpxC deacetylase from Aquifex aeolicus in complex with the substrate-analog inhibitor TU-514.
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Bacteria-host cell interaction mediated by cellular cholesterol/glycolipid-enriched microdomains.
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Biliary excretion of glycolipid in induced or inherited glucosylceramide lipidosis.
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Caulobacter crescentus Adapts to Phosphate Starvation by Synthesizing Anionic Glycoglycerolipids and a Novel Glycosphingolipid.
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Cellular adhesion and the endothelium: E-selectin, L-selectin, and pan-selectin inhibitors.
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Circulating glycoconjugates in CSF of meningioma patients.
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Combined analysis of plasma or serum glucosylsphingosine and globotriaosylsphingosine by UPLC-MS/MS.
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Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis.
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Dr(a-) polymorphism of decay accelerating factor. Biochemical, functional, and molecular characterization and production of allele-specific transfectants.
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Glycolipid depletion using a ceramide analogue (PDMP) alters growth, adhesion, and membrane lipid organization in human A431 cells.
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Glycolipids and glycosyltransferases in permanent cell lines established from human medulloblastomas.
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Glycosylation of serum HDL and LDL in rats given excess retinol.
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Hepatic monoacylglycerol acyltransferase: ontogeny and characterization of an activity associated with the chick embryo.
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How well does urinary lyso-Gb3 function as a biomarker in Fabry disease?
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Human UDP-galactose 4'-epimerase (GALE) is required for cell-surface glycome structure and function.
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Identification of a novel cationic glycolipid in Streptococcus agalactiae that contributes to brain entry and meningitis.
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Improving Mycobacterium bovis bacillus Calmette-Guèrin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells.
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Increased expression of sialyl-dimeric LeX antigen in liver metastases of human colorectal carcinoma.
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Inhibition of protein synthesis also inhibits synthesis of lipid-linked oligosaccharides.
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Isolation and characterization of biliary epithelial cells from rainbow trout liver.
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Kdo hydroxylase is an inner core assembly enzyme in the Ko-containing lipopolysaccharide biosynthesis.
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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation.
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Mapping bacterial glycolipid complexity using capillary electrophoresis and electrospray mass spectrometry.
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Metastatic behavior and cell surface properties of HT-29 human colon carcinoma variant cells selected for their differential expression of sialyl-dimeric Le(x)-antigen.
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Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids.
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Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli.
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Phase 1 study of the E-selectin inhibitor GMI 1070 in patients with sickle cell anemia.
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Phenylalanine 30 plays an important role in receptor binding of verotoxin-1.
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Phosphatidylcholine Biosynthesis in Mitis Group Streptococci via Host Metabolite Scavenging.
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Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use.
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Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design.
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Relationship between insulin-mediated turnover of glucosamine-labeled lipids and activity of the insulin receptor tyrosine kinase.
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Streptococcus pneumoniae, S. mitis, and S. oralis Produce a Phosphatidylglycerol-Dependent, ltaS-Independent Glycerophosphate-Linked Glycolipid.
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Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis.
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Structure-Activity Relationship of Sulfonyl Piperazine LpxH Inhibitors Analyzed by an LpxE-Coupled Malachite Green Assay.
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T Cell Responses against Mycobacterial Lipids and Proteins Are Poorly Correlated in South African Adolescents.
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The footprint of antibody bound to pig cells: evidence of complex surface topology.
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The inflammatory response and resistance to endotoxin in mice.
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Time to treatment benefit for adult patients with Fabry disease receiving agalsidase β: data from the Fabry Registry.