Gram-Positive Bacteria

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  Subject Areas on Research

  • A Phase 3, Randomized, Double-Blind, Multicenter Study To Evaluate the Safety and Efficacy of Intravenous Iclaprim versus Vancomycin for Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed To Be Due to Gram-Positive Pathogens (REVIVE-2 Study). 
  • A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Iclaprim Vs Vancomycin for the Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed to be Due to Gram-Positive Pathogens: REVIVE-1. 
  • A crystal structure of a dimer of the antibiotic ramoplanin illustrates membrane positioning and a potential Lipid II docking interface. 
  • Adherent biofilms in bacterial vaginosis. 
  • Alteration in vaginal microflora, douching prior to pregnancy, and preterm birth. 
  • Analysis of bacterial cultures in infectious keratitis, 1997 to 2004. 
  • Antibacterial Resistance Leadership Group 2.0: Back to Business. 
  • Autocatalytic intramolecular isopeptide bond formation in gram-positive bacterial pili: a QM/MM simulation. 
  • Bacteremia in lung transplant recipients in the current era. 
  • Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate. 
  • Bacteriologic features of surgical site infections following breast surgery. 
  • Catheter-related bacteremia and outcome of attempted catheter salvage in patients undergoing hemodialysis. 
  • Clinical consensus conference: survey on Gram-positive bloodstream infections with a focus on Staphylococcus aureus. 
  • Complications of implantable venous access devices in patients with sickle cell disease. 
  • Critical shortage of new antibiotics in development against multidrug-resistant bacteria-Time to react is now. 
  • Defining wound microbial flora: molecular microbiology opening new horizons. 
  • Diagnostic methods to determine microbiology of postpartum endometritis in South Asia: laboratory methods protocol used in the Postpartum Sepsis Study: a prospective cohort study. 
  • Discovery of Six Ramoplanin Family Gene Clusters and the Lipoglycodepsipeptide Chersinamycin*. 
  • Early and late onset sepsis in late preterm infants. 
  • Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units. 
  • Gram-Positive Bacterial Infections: Research Priorities, Accomplishments, and Future Directions of the Antibacterial Resistance Leadership Group. 
  • How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria. 
  • Iclaprim: a differentiated option for the treatment of skin and skin structure infections. 
  • Immunostimulatory properties of genomic DNA from different bacterial species. 
  • In vitro efficacy of a polyhexamethylene biguanide-impregnated gauze dressing against bacteria found in veterinary patients. 
  • Is bacterial fatty acid synthesis a valid target for antibacterial drug discovery? 
  • Microbiology of ventilator-associated pneumonia compared with that of hospital-acquired pneumonia. 
  • Offense and defense: microbial membrane vesicles play both ways. 
  • Overview of first-line amikacin therapy for urologic infections. 
  • Phagocytic and tumor necrosis factor alpha response of human mast cells following exposure to gram-negative and gram-positive bacteria. 
  • Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections. 
  • Phylogeny of the Whipple's-disease-associated bacterium. 
  • Plasma concentrations of tumour necrosis factor-alpha and interleukin-6 during burn wound surgery or dressing. 
  • Pooled analysis of single-dose oritavancin in the treatment of acute bacterial skin and skin-structure infections caused by Gram-positive pathogens, including a large patient subset with methicillin-resistant Staphylococcus aureus. 
  • Safety and efficacy of quinupristin/dalfopristin for treatment of invasive Gram-positive infections in pediatric patients. 
  • Single Intravenous Dose of Oritavancin for Treatment of Acute Skin and Skin Structure Infections Caused by Gram-Positive Bacteria: Summary of Safety Analysis from the Phase 3 SOLO Studies. 
  • Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition. 
  • Specificity and immunochemical properties of antibodies to bacterial DNA in sera of normal human subjects and patients with systemic lupus erythematosus (SLE). 
  • Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract. 
  • Studies on the biosynthesis of the lipodepsipeptide antibiotic Ramoplanin A2. 
  • Tedizolid (TR-701): a new oxazolidinone with enhanced potency. 
  • Telavancin versus standard therapy for treatment of complicated skin and skin structure infections caused by gram-positive bacteria: FAST 2 study. 
  • Telavancin versus vancomycin for the treatment of complicated skin and skin-structure infections caused by gram-positive organisms. 
  • The North American component (the United States and Canada) of an International Comparative MIC trial monitoring ofloxacin resistance. 
  • The Vitek analyser for routine bacterial identification and susceptibility testing: protocols, problems, and pitfalls. 
  • The development and evaluation of a community-based clinical diagnosis tool and treatment regimen for postpartum sepsis in Bangladesh and Pakistan. 
  • The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. 
  • The extracellular vesicle generation paradox: a bacterial point of view. 
  • [In vitro studies on antioxidant and antimicrobial activities of polysaccharide from Lycoris aurea]. 
  • “A robust platform for the synthesis of new tetracycline antibiotics 
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  Keywords of People

  • Cohen-Wolkowiez, Michael, Kiser-Arena Distinguished Professor, Pediatrics, Infectious Diseases