Guinea Pigs

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  Subject Areas on Research

  • 3D-Printed Microneedles Create Precise Perforations in Human Round Window Membrane in Situ. 
  • A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques. 
  • A chemoattractant receptor on macrophages exists in two affinity states regulated by guanine nucleotides. 
  • A chemotactic factor for mononuclear leukocytes. 
  • A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis. 
  • A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120. 
  • A fatal x-linked recessive reticuloendothelial syndrome with hyperglobulinemia. X-linked recessive reticuloendotheliosis. 
  • A fusion intermediate gp41 immunogen elicits neutralizing antibodies to HIV-1. 
  • A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. 
  • A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis. 
  • A mathematical model for analysis of pharmacologically induced changes in the kinetics of cardiac muscle. 
  • A neutrophil chemotatic factor derived from C'5 upon interaction of guinea pig serum with endotoxin. 
  • A prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity. 
  • A proarrhythmic response to sodium channel blockade: modulation of the vulnerable period in guinea pig ventricular myocardium. 
  • A randomized controlled trial of trypsin to treat brown recluse spider bites in Guinea pigs. 
  • ATP receptor activation potentiates a voltage-dependent Ca channel in hippocampal neurons. 
  • Ability of epinephrine, but not increased extracellular calcium, to reverse the effects of verapamil on ventricular automaticity in vitro. 
  • Action potential and QT prolongation not sufficient to cause Torsade de Pointes: role of action potential triangulation. 
  • Activation of complement by endotoxin. 
  • Activation of complement by endotoxin: a role for 2 globulin, C1, C4 and C2 in the consumption of terminal complement components by endotoxin-coated erythrocytes. 
  • Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models. 
  • Adrenergic receptors: molecular mechanisms of clinically relevant regulation. 
  • Age-related thymic atrophy in the guinea pig. 
  • Alpha 2 adrenergic receptors are located prejunctionally in the Auerbach's plexus of the guinea pig small intestine: direct demonstration by radioligand binding. 
  • Alterations of new methylated phospholipid synthesis in the plasma membranes of macrophages exposed to chemoattractants. 
  • An HIV-1 vaccine based on bacterium-like particles elicits Env-specific mucosal immune responses. 
  • Analysis of HIV-1 subtype B third variable region peptide motifs for induction of neutralizing antibodies against HIV-1 primary isolates. 
  • Analysis of the defibrillation efficacy for 5-ms waveforms. 
  • Anatomical and Functional Consequences of Microneedle Perforation of Round Window Membrane. 
  • Ancestral and consensus envelope immunogens for HIV-1 subtype C. 
  • Anti-inflammatory and vasoprotective activity of a retroviral-derived peptide, homologous to human endogenous retroviruses: endothelial cell effects. 
  • Antiallergy Agents. 1. Substituted 1,8-Naphthyridin-2-(1H)-ones as Inhibitors of SRS-A Release 
  • Antiarrhythmic drug action: selective depression of hypoxic cardiac cells. 
  • Antibody to VLA-4, but not to L-selectin, protects neuronal M2 muscarinic receptors in antigen-challenged guinea pig airways. 
  • Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins. 
  • Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1. 
  • Antioxidant and cytotoxic tocopheryl quinones in normal and cancer cells. 
  • Ascorbic acid accumulates in cartilage in vivo. 
  • Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model. 
  • Assessment of the utility of biomarkers of osteoarthritis in the guinea pig. 
  • Assignment of the zeta-crystallin gene (CRYZ) to human chromosome 1p22-p31 and identification of restriction fragment length polymorphisms. 
  • Automated feedback control of body temperature for small animal studies with MR microscopy. 
  • Beta-adrenergic receptors: biochemical mechanisms of physiological regulation. 
  • Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro. 
  • Biochemical characterization of the adrenergic receptors: affinity labeling, purification, and reconstitution studies. 
  • Biological activity of complement in vivo. Role of C5 in the accumulation of polymorphonuclear leukocytes in inflammatory exudates. 
  • Biological evaluation of some biphenyl analogs of acetyl-seco-hemicholinium No. 3. 
  • Brain Stimulation Differentially Modulates Nociception and Inflammation in Aversive and Non-aversive Behavioral Conditions. 
  • Breadth of neutralizing antibodies elicited by stable, homogeneous clade A and clade C HIV-1 gp140 envelope trimers in guinea pigs. 
  • Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor. 
  • Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1. 
  • Calorimetry and respirometry in guinea pigs in hydrox and heliox at 10-60 atm. 
  • Cardiac CaV1.2 channels require β subunits for β-adrenergic-mediated modulation but not trafficking. 
  • Cardiac microimpedance measurement in two-dimensional models using multisite interstitial stimulation. 
  • Cartilage mechanics in the guinea pig model of osteoarthritis studied with an osmotic loading method. 
  • Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem. 
  • Chaperone-like activity of alpha-crystallin. The effect of NADPH on its interaction with zeta-crystallin. 
  • Characteristics of corneal xenograft rejection in a discordant species combination. 
  • Characterization of a novel family of ciliary body glycoproteins. 
  • Characterization of a novel human corneal endothelial antigen. 
  • Characterization of an oligopeptide chemoattractant receptor on human blood monocytes using a new radioligand. 
  • Characterization of chemotactic activity produced in vivo by a cell-mediated immune reaction in the guinea pig. 
  • Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement. 
  • Chemotaxis of mononuclear leukocytes. 
  • Ciprofloxacin. Use as a topical otic preparation. 
  • Collagen fibril disruption occurs early in primary guinea pig knee osteoarthritis. 
  • Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis. 
  • Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor. 
  • Comparative analysis of the zeta-crystallin/quinone reductase gene in guinea pig and mouse. 
  • Comparative immunogenicity of HIV-1 clade C envelope proteins for prime/boost studies. 
  • Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector. 
  • Comparative tissue distribution in mice of the alpha-emitter 211At and 131I as labels of a monoclonal antibody and F(ab')2 fragment. 
  • Comparison of HIV Type 1 ADA gp120 monomers versus gp140 trimers as immunogens for the induction of neutralizing antibodies. 
  • Comparison of packing material in an animal model of middle ear trauma. 
  • Competitive and non-competitive re-innervation of mammalian sympathetic neurones by native and foreign fibres. 
  • Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro. 
  • Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine. 
  • Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. 
  • Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting. 
  • Construction of a very high-density extracellular electrode array. 
  • Consumption of hamster complement by bacterial endotoxin. 
  • Control of liver and brain aromatic amino-acid metabolism by phenylalanine hydroxylase. 
  • Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity. 
  • Cross-linking of fibrin by fibrin=stabilizing factor. 
  • Cutaneous herpes simplex virus infection of guinea pigs as a model for antiviral chemotherapy. 
  • Cytogenetic engineering in vivo: restoration of biologic complement activity to C5-deficient mice by intravenous inoculation of hybrid cells. 
  • Defibrillation and the upper limit of vulnerability to fibrillation in a transthoracic guinea pig model. 
  • Deficiency of double-strand DNA break repair does not impair Mycobacterium tuberculosis virulence in multiple animal models of infection. 
  • Demonstration of a chemotactic factor receptor on macrophages. 
  • Dermal and ocular exposure systems for the development of models of sulfur mustard-induced injury. 
  • Descending auditory pathways: projections from the inferior colliculus contact superior olivary cells that project bilaterally to the cochlear nuclei. 
  • Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics. 
  • Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (+-)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3- (dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid. 
  • Development of an affinity ligand for purification of alpha 2-adrenoceptors from human platelet membranes. 
  • Diagnosis of endolymphatic hydrops in vivo with magnetic resonance imaging. 
  • Different ontogeny of rate of force generation and shortening velocity in guinea pig trachealis. 
  • Differential activity of protein kinase C in alveolar and peritoneal macrophages. 
  • Differential effect of HERG blocking agents on cardiac electrical alternans in the guinea pig. 
  • Differential localization of cholecystokinin-8 binding sites in the rat vs. the guinea pig brain. 
  • Dioxinlike properties of a trichloroethylene combustion-generated aerosol. 
  • Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species. 
  • Dynamical mechanism for subcellular alternans in cardiac myocytes. 
  • Dynamics of magnetization in hyperpolarized gas MRI of the lung. 
  • Effect of C4 depletion on the utilization of the terminal components of guinea-pig complement by endotoxin. 
  • Effect of Cochlear Implantation on the Endocochlear Potential and Stria Vascularis. 
  • Effect of allergic bronchoconstriction on airways epithelial permeability to large polar solutes in the guinea pig. 
  • Effect of dihydrostreptomycin on tissue lipid of guinea-pigs. 
  • Effect of dihydrostreptomycin on tissue lipids of tuberculous guinea-pigs. 
  • Effect of electrode surface area on thresholds for AC stimulation and ventricular fibrillation. 
  • Effect of helium and heliox on glutamate decarboxylase activity. 
  • Effect of nerve growth factor on synaptic depression after axotomy. 
  • Effect of soluble complement receptor type 1 on natural antibody levels during xenograft rejection. 
  • Effects of [Nphe1]nociceptin(1-13)NH2, [Phe1(CH2-NH)Gly2]nociceptin(1- 13)NH2, and nocistatin on nociceptin inhibited constrictions of guinea pig isolated bronchus. 
  • Effects of carbon tetrachloride on adrenocortical structure and function in guinea pigs. 
  • Effects of droperidol on depolarization-induced automaticity, maximum upstroke velocity (Vmax) and the kinetics of recovery of Vmax in guinea-pig ventricular myocardium. 
  • Effects of perchlorate on the molecules of excitation-contraction coupling of skeletal and cardiac muscle. 
  • Electrical alternans and hemodynamics in the anesthetized guinea pig can discriminate the cardiac safety of antidepressants. 
  • Electrical characteristics of dendrites and dendritic spines in intracellularly stained CA3 and dentate hippocampal neurons. 
  • Electroporation and shock-induced transmembrane potential in a cardiac fiber during defibrillation strength shocks. 
  • Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins. 
  • Enhanced macrophage tumoricidal activity and tumor suppression or regression caused by heat-killed Candida albicans. 
  • Environmental aspects of fibrous glass production and utilization. 
  • Epitope insertion into variable loops of HIV-1 gp120 as a potential means to improve immunogenicity of viral envelope protein. 
  • Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. 
  • Evaluation of drug action using spectrographic analysis of evoked vocalization. 
  • Evaluation of humoral, mucosal, and cellular immune responses following co-immunization of HIV-1 Gag and Env proteins expressed by Newcastle disease virus. 
  • Evidence for independent recruitment of zeta-crystallin/quinone reductase (CRYZ) as a crystallin in camelids and hystricomorph rodents. 
  • Experimental allergic encephalomyelitis in Lewis rats bearing avian sarcoma virus-induced brain tumors. 
  • Experimental cardiac tachyarrhythmias in guinea pigs. 
  • Experimental evidence of improved transthoracic defibrillation with electroporation-enhancing pulses. 
  • Experimental verification of theoretical predictions concerning the optimum defibrillation waveform. 
  • Exploring the role of pH in modulating the effects of lidocaine in virtual ischemic tissue. 
  • Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry. 
  • Expression of matrix metalloproteinase 1 in rodents: comment on the article by Huebner et al. 
  • Extremely high levels of NADPH in guinea pig lens: correlation with zeta-crystallin concentration. 
  • Feed-forward inhibitory potentials and excitatory interactions in guinea-pig hippocampal pyramidal cells. 
  • Fibronectin isoforms in megakaryocytes. 
  • Fibrous glass and cancer. 
  • Field-induced forces at dielectric interfaces as a possible mechanism of RF hearing effects. 
  • Fourier analysis of cytoplasmic texture in nuclear fiber cells from transparent and cataractous human and animal lenses. 
  • Frequency dependence of the cardiac threshold to alternating current between 10 Hz and 160 Hz. 
  • Functional MR microscopy of the lung using hyperpolarized 3He. 
  • Functional and structural changes in mammalian sympathetic neurones following colchicine application to post-ganglionic nerves. 
  • Functional and structural changes in mammalian sympathetic neurones following interruption of their axons. 
  • Further characterization of a factor from endotoxin-treated serum which releases histamine and heparin from mast cells. 
  • Further studies on the role of the gonads in determining the ontogeny of gonadotropin secretion in the guinea pig (Cavia porcelus). 
  • GABA receptor-mediated chloride transport in a "cell-free" membrane preparation from brain. 
  • Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant. 
  • Geometrical differences among homologous neurons in mammals. 
  • Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies. 
  • Glycosaminoglycan binding properties of natural venezuelan equine encephalitis virus isolates. 
  • Growth of nutritionally variant streptococci on laboratory media supplemented with blood of eight animal species. 
  • Guinea pig and bovine zeta-crystallins have distinct functional characteristics highlighting replacements in otherwise similar structures. 
  • H3N2 influenza hemagglutination inhibition method qualification with data driven statistical methods for human clinical trials. 
  • HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. 
  • Hemodynamic effects of metalloporphyrin catalytic antioxidants: structure-activity relationships and species specificity. 
  • Hexabromonaphthalene contaminants of polybrominated biphenyls: chemical composition and disposition in the rat. 
  • Histologic evaluation of fetal brains following maternal pneumoperitoneum. 
  • Histopathologic features of rejecting orthotopic corneal xenografts. 
  • Hormonal activation of adenylate cyclase in macrophage membranes is regulated by guanine nucleotides. 
  • How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. 
  • Human Factor XIII from plasma and platelets. Molecular weights, subunit structures, proteolytic activation, and cross-linking of fibrinogen and fibrin. 
  • Humoral mediators of chemotaxis of mononuclear leukocytes. 
  • Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. 
  • Hyperpolarized 3He NMR lineshape measurements in the live guinea pig lung. 
  • Hypersecretion of mucin in response to inflammatory mediators by guinea pig tracheal epithelial cells in vitro is blocked by inhibition of nitric oxide synthase. 
  • Identification and characterization of the enzymatic activity of zeta-crystallin from guinea pig lens. A novel NADPH:quinone oxidoreductase. 
  • Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists. 
  • Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic Guinea pigs. 
  • IgG and complement-mediated tissue damage in the absence of C2: evidence of a functionally active C2-bypass pathway in a guinea pig model. 
  • Imaging inflammation: direct visualization of perivascular cuffing in EAE by magnetic resonance microscopy. 
  • Immunodiagnosis of infection with Schistosoma mansoni: enzyme-linked immunosorbent assay for detection of antibody to circulating antigen. 
  • Immunogenicity of constrained monoclonal antibody A32-human immunodeficiency virus (HIV) Env gp120 complexes compared to that of recombinant HIV type 1 gp120 envelope glycoproteins. 
  • Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion state. 
  • Immunological mechanisms of periodontal tissue destruction. 
  • Improved guinea pig model of cardiac tachyarrhythmias. 
  • In vivo He-3 MR images of guinea pig lungs. 
  • In vivo accumulation of iron on crocidolite is associated with decrements in oxidant generation by the fiber. 
  • Induction and characterization of neutralizing antibodies against a human immunodeficiency virus type 1 primary isolate. 
  • Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains. 
  • Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41. 
  • Induction of lethal experimental allergic encephalomyelitis in nonhuman primates and guinea pigs with human glioblastoma multiforme tissue. 
  • Induction of preneoplastic lung lesions in guinea pigs by cigarette smoke inhalation and their exacerbation by high dietary levels of vitamins C and E. 
  • Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells. 
  • Inflammation and viral infection: chemotactic activity resulting from the interaction of antiviral antibody and complement with cells infected with herpes simplex virus. 
  • Influence of buffers on dV/dtmax recovery kinetics with lidocaine in myocardium. 
  • Influence of cytoskeletal assembly on phosphatidylcholine synthesis in intact phagocytic cells. 
  • Innervation of sympathetic neurones in the guinea-pig thoracic chain. 
  • Insulin or glucagon choleresis in the isolated perfused guinea pig liver. 
  • Insulin receptor of fat cells in insulin-resistant metabolic states. 
  • Interaction of complex polysaccharides with the complement system: effect of calcium depletion on terminal component consumption. 
  • Interaction of macrophages and lymphocytes for lymphokine production and cellular proliferation. 
  • Interactions of the complement system with endotoxic lipopolysaccharide. Generation of a factor chemotactic for polymorphonuclear leukocytes. 
  • Isolation and characterization of C4-synthesizing cells from guinea-pig spleen. 
  • Isolation and characterization of a receptor for type 1 fimbriae of Escherichia coli from guinea pig erythrocytes. 
  • LOCALIZATION OF IMMUNOGLOBULINS IN CHRONIC THYROIDITIS. 
  • Large sample test of defibrillation waveform sensitivity. 
  • Length oscillation induces force potentiation in infant guinea pig airway smooth muscle. 
  • Letter: Cardiac ventricular automaticity induced by current of injury. 
  • Lipid requirements for leukocyte chemotaxis and phagocytosis: effects of inhibitors of phospholipid and cholesterol synthesis. 
  • Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium. 
  • Local anesthetic activity and acute toxicity of N-heptyl-1,2,3,4-tetrahydro-6-methoxy-1-naphthylamine methanesulfonate. 
  • Local drug delivery to conserve hearing: mechanisms of action of eluted dexamethasone within the cochlea. 
  • Localization of functionally different guinea-pig spleen cells in albumin gradients. 
  • Localization of specific binding sites for atrial natriuretic factor in peripheral tissues of the guinea pig, rat, and human. 
  • Localization of specific binding sites for atrial natriuretic factor in the central nervous system of rat, guinea pig, cat and human. 
  • Long-term behavioral assessment of guinea pigs following neonatal pneumoperitoneum. 
  • LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo. 
  • MR imaging with hyperpolarized 3He gas. 
  • MR microimaging of the lung using volume projection encoding. 
  • MR microscopy of lung airways with hyperpolarized 3He. 
  • MR-compatible ventilator for small animals: computer-controlled ventilation for proton and noble gas imaging. 
  • Macrophage proteinase and inflammation: the production of chemotactic activity from the fifth complement by macrophage proteinase. 
  • Magnetic resonance imaging of guinea pig cochlea after vasopressin-induced or surgically induced endolymphatic hydrops. 
  • Maturation of guinea pig tracheal strip stiffness. 
  • Measurements of hyperpolarized gas properties in the lung. Part III: (3)He T(1). 
  • Mechanical ventilation for imaging the small animal lung. 
  • Mechanism of activation of adenylate cyclase by Vibrio cholerae enterotoxin. Relations to the mode of activation by hormones. 
  • Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system. 
  • Mechanisms of apparent affinity variation of guarded receptors. 
  • Mechanisms regulating variability of the single photon responses of mammalian rod photoreceptors. 
  • Microscopic variations in interstitial and intracellular structure modulate the distribution of conduction delays and block in cardiac tissue with source-load mismatch. 
  • Middle ear packing: comparison of materials in an animal model of mucosal trauma. 
  • MinK-dependent internalization of the IKs potassium channel. 
  • Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization. 
  • Modified Newcastle Disease virus as an improved vaccine vector against Simian Immunodeficiency virus. 
  • Molecular and cellular mechanisms of leukocyte chemotaxis. 
  • Movement characteristics and power output of guinea-pig and hamster spermatozoa in relation to activation. 
  • Movement characteristics of hamster and guinea pig spermatozoa upon attachment to the zona pellucida. 
  • Mucosal Immunization with Newcastle Disease Virus Vector Coexpressing HIV-1 Env and Gag Proteins Elicits Potent Serum, Mucosal, and Cellular Immune Responses That Protect against Vaccinia Virus Env and Gag Challenges. 
  • Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component. 
  • Mutant zeta-crystallin from guinea-pig hereditary cataracts has altered structural and enzymatic properties. 
  • Myocardial guanylate cyclase: properties of the enzyme and effects of cholinergic agonists in vitro. 
  • Myocardial involvement in Rocky Mountain spotted fever. 
  • Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates. 
  • Neural units in the superior cervical ganglion of the guinea-pig. 
  • Neuromuscular blocking agents' differential bronchoconstrictive potential in Guinea pig airways. 
  • Neutralization of sensitized virus by purified components of complement. 
  • Newspapers and newspaper ink contain agonists for the ah receptor. 
  • Non-human to human organ transplantation: its biologic basis and a potential role for radiation therapy. 
  • Nonclinical Safety and Toxicokinetics of MnTnBuOE-2-PyP5+ (BMX-001). 
  • Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina. 
  • Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. 
  • On the purpose of selective innervation of guinea-pig superior cervical ganglion cells. 
  • Ongoing electrical activity of superior cervical ganglion cells in mammals of different size. 
  • Ontogenesis of myosin light chain kinase mRNA and protein content in guinea pig tracheal smooth muscle. 
  • Ontogenesis of myosin light chain phosphorylation in guinea pig tracheal smooth muscle. 
  • Ontogeny of dry gas hyperpnea-induced bronchoconstriction in guinea pigs. 
  • Open Na+ channel blockade: multiple rest states revealed by channel interactions with disopyramide and quinidine. 
  • Open-thorax guinea pig model for defibrillation. 
  • Organization of the human zeta-crystallin/quinone reductase gene (CRYZ). 
  • Organization of the superior olivary complex in the guinea pig. I. Cytoarchitecture, cytochrome oxidase histochemistry, and dendritic morphology. 
  • Organization of the superior olivary complex in the guinea pig: II. Patterns of projection from the periolivary nuclei to the inferior colliculus. 
  • Origins and targets of commissural connections between the cochlear nuclei in guinea pigs. 
  • Osmotic loading to determine the intrinsic material properties of guinea pig knee cartilage. 
  • Outer membrane of avian myeloblastosis virus. 
  • Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism. 
  • PH-Dependent effects of quinidine on the kinetics of dV/dtmax in guinea pig ventricular myocardium. 
  • Periodontal disease: a model for the study of inflammation. 
  • Persistent innervation of mammalian sympathetic neurones by native and foreign fibres. 
  • Phospholipid methylation in macrophages is inhibited by chemotactic factors. 
  • Photoaffinity labeling of beta-adrenergic receptors in mammalian tissues. 
  • Photoaffinity labeling of mammalian alpha 1-adrenergic receptors. Identification of the ligand binding subunit with a high affinity radioiodinated probe. 
  • Placental transport of free palmitic and linoleic acids in the guinea pig. 
  • Polarized distribution of Mr 210,000 and 190,000 analogs of erythrocyte ankyrin along the plasma membrane of transporting epithelia, neurons and photoreceptors. 
  • Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases? 
  • Precision and accuracy of a transportable dual-energy X-ray absorptiometry unit for bone mineral measurements in guinea pigs. 
  • Pregnancy and estradiol decrease GTPase activity in the guinea pig uterine artery. 
  • Pregnancy and estradiol modulate myometrial G-protein pathways in the guinea pig. 
  • Prevention of laboratory animal allergy. 
  • Proceedings: Immunologic similarities between fetal cell antigens and tumor cell antigens in guinea pigs. 
  • Production of chemotactic activity by guinea pig immunoglobulins following activation of the C3 complement shunt pathway. 
  • Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C. 
  • Projections from the ventral cochlear nucleus to the inferior colliculus and the contralateral cochlear nucleus in guinea pigs. 
  • Proliferative glomerulonephritis in children. A correlation of varied clinical and pathologic patterns utilizing light, immunofluorescence, and electron microscopy. 
  • Protein kinase C mediates potentiation of synaptic transmission by phorbol ester at parallel fibers in the dorsal cochlear nucleus. 
  • Proteolytic cleavage and PKA phosphorylation of α1C subunit are not required for adrenergic regulation of CaV1.2 in the heart. 
  • Pure beta-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase. 
  • Purification and characterization of zeta-crystallin/quinone reductase from guinea pig liver. 
  • Purification and properties of DNA polymerase-beta from guinea pig liver. 
  • Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation. 
  • Rapacuronium augments acetylcholine-induced bronchoconstriction via positive allosteric interactions at the M3 muscarinic receptor. 
  • Rapacuronium preferentially antagonizes the function of M2 versus M3 muscarinic receptors in guinea pig airway smooth muscle. 
  • Re-innervation of ganglia transplanted to the neck from different levels of the guinea-pig sympathetic chain. 
  • Re-innervation of guinea-pig superior cervical ganglion cells by preganglionic fibres arising from different levels of the spinal cord. 
  • Reaction of a cobra venom factor with guinea pig complement and generation of an activity chemotactic for polymorphonuclear leukocytes. 
  • Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit. 
  • Reduced spontaneous relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release. 
  • Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans. 
  • Regulation of mononuclear leukocyte function by transmethylation reactions. 
  • Relation of animal size to convergence, divergence, and neuronal number in peripheral sympathetic pathways. 
  • Relaxation of guinea pig trachealis during electrical field stimulation increases with age. 
  • Responses of ventral cochlear nucleus neurons to contralateral sound after conductive hearing loss. 
  • Rhipicephalus sanguineus: vector of a new spotted fever group rickettsia in the United States. 
  • Role of transmethylation reactions in cellular motility and phagocytosis. 
  • Segmental cable evaluation of somatic transients in hippocampal neurons (CA1, CA3, and dentate). 
  • Selective O-desulfation produces nonanticoagulant heparin that retains pharmacological activity in the lung. 
  • Sensitivity and resolution in 3D NMR microscopy of the lung with hyperpolarized noble gases. 
  • Serological evidence of cross infection in a dialysis unit hepatitis-B epidemic. 
  • Signal dynamics in magnetic resonance imaging of the lung with hyperpolarized noble gases. 
  • Soluble Envelope Glycoprotein Trimers from a CD4-Independent HIV-1 Elicit Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Guinea Pigs. 
  • Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part I: diffusion coefficient. 
  • Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part II: T *(2). 
  • Species differences in cardiac thyroid hormone receptor isoforms protein abundance. 
  • Specific innervation of guinea-pig superior cervical ganglion cells by preganglionic fibres arising from different levels of the spinal cord. 
  • Specificity of initial synaptic contacts made on guinea-pig superior cervical ganglion cells during regeneration of the cervical sympathetic trunk. 
  • Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles. 
  • Steady-state electrotonic analysis of intracellularly stained hippocampal neurons. 
  • Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl] [[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist. 
  • Structure and domain organization of the CD19 antigen of human, mouse, and guinea pig B lymphocytes. Conservation of the extensive cytoplasmic domain. 
  • Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity. 
  • Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies. 
  • Studies of the conformation-dependent neutralizing epitopes of simian immunodeficiency virus envelope protein. 
  • Substance P dependence of endosomal fusion during bladder inflammation. 
  • Synthesis and NK(1)/NK(2) binding activities of a series of diacyl-substituted 2-arylpiperazines. 
  • Synthesis and biological activity of zoapatanol analogues. 
  • Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity. 
  • Synthesis and secretion of von Willebrand factor and fibronectin in megakaryocytes at different phases of maturation. 
  • Temperature regulation in laboratory mammals following acute toxic insult. 
  • The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the guinea pig. 
  • The defibrillation efficacy of high frequency alternating current sinusoidal waveforms in guinea pigs. 
  • The development of homologous skin-sensitizing antibodies in experimental thyroiditis. 
  • The effect of soluble complement receptor type 1 on hyperacute xenograft rejection. 
  • The effect of tremorine on dopamine concentration in the brain of the rat, guinea pig and rabbit. 
  • The effect of unilateral limb shielding on the haemopoietic response of the guinea-pig to gamma irradiation (150 r.). 
  • The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants. 
  • The effects of nerve growth factor and its antiserum on synapses in the superior cervical ganglion of the guinea-pig. 
  • The effects of post-ganglionic axotomy on selective synaptic connexions in the superior cervical ganglion of the guinea-pig. 
  • The effects of quinidine and verapamil on electrically induced automaticity in the ventricular myocardium of guinea pig. 
  • The high-affinity immunoglobulin receptor FcγRI potentiates HIV-1 neutralization via antibodies against the gp41 N-heptad repeat. 
  • The impact of aging on adrenergic receptor function: clinical and biochemical aspects. 
  • The infectiousness of tuberculosis patients coinfected with HIV. 
  • The influence of pH on th electrophysiological effects of lidocaine in guinea pig ventricular myocardium. 
  • The mammalian beta 2-adrenergic receptor: purification and characterization. 
  • The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system. 
  • The physiologic consequences of vas ligation. 
  • The regulation of the cGMP-binding cGMP phosphodiesterase by proteins that are immunologically related to gamma subunit of the photoreceptor cGMP phosphodiesterase. 
  • The resolution, isolation, and pharmacological characterization of the enantiomers of a benzamide containing a chiral sulfoxide. 
  • The role of the immune response in the development of periodontal disease. 
  • The structure of mononuclear phagocytes differentiating in vivo. III. The effect of particulate foreign substances. 
  • The synthesis and secretion of gamma-globulin by lymph node cells. V. The dissociation of the microsome-antibody complex with enzymatically and chemically altered gamma-globulins. 
  • Three paradigms of airway smooth muscle hyperresponsiveness in young guinea pigs. 
  • Traffic-related air pollution induces non-allergic eosinophilic airway inflammation and cough hypersensitivity in guinea-pigs. 
  • Transformation of mu-opioid receptor agonists into biologically potent mu-opioid receptor antagonists. 
  • Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA. 
  • Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length. 
  • Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages. 
  • Tumor necrosis factor-alpha (TNF-alpha) stimulates mucin secretion and gene expression in airway epithelium in vitro. 
  • Tumor necrosis factor-alpha stimulates mucin secretion and cyclic GMP production by guinea pig tracheal epithelial cells in vitro. 
  • Two-dimensional analysis of ventricular fibrillation in the guinea pig. 
  • Ultrastructural characterization and Fourier analysis of fiber cell cytoplasm in the hyperbaric oxygen treated guinea pig lens opacification model. 
  • Use of poly-l-aspartic acid to inhibit aminoglycoside cochlear ototoxicity. 
  • Use of resampling techniques to estimate the variance of parameters in pharmacological assays when experimental protocols preclude independent replication: an example using Schild regressions. 
  • Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates. 
  • Vaccine with bacterium-like particles displaying HIV-1 gp120 trimer elicits specific mucosal responses and neutralizing antibodies in rhesus macaques. 
  • Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site. 
  • Ventral cochlear nucleus responses to contralateral sound are mediated by commissural and olivocochlear pathways. 
  • Ventral nucleus of the lateral lemniscus in guinea pigs: cytoarchitecture and inputs from the cochlear nucleus. 
  • Virulence and viremia characteristics of 1992 epizootic subtype IC Venezuelan equine encephalitis viruses and closely related enzootic subtype ID strains. 
  • Visualization of purified fibronectin-transglutaminase complexes. 
  • Voltage clamp discloses slow inward current in hippocampal burst-firing neurones. 
  • Waveform and amplitude characteristics of evoked responses to dendritic stimulation of CA1 guinea-pig pyramidal cells. 
  • Xenobiotic induction of quinone oxidoreductase activity in lens epithelial cells. 
  • Zeta-crystallin from guinea pig lens is capable of functioning catalytically as an oxidoreductase. 
  • Zeta-crystallin versus other members of the alcohol dehydrogenase super-family. Variability as a functional characteristic. 
  • [Characteristics of cells producing immune interferon]. 
  • [Experimental study of streptomycin on 45Ca intake of otolithic membranes]. 
  • [Histochemical studies on the medial regions of the brainstem in guinea pigs]. 
  • [The influence of labyrinthectomy on the expression of NMDA R1 mRNA]. 
  • [Traverse connectivity of innervation in the vestibular sensory epithelium]. 
  • p47 GTPases regulate Toxoplasma gondii survival in activated macrophages. 
  • pKa does not predict pH potentiation of sodium channel blockade by lidocaine and W6211 in guinea pig ventricular myocardium. 
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  Keywords of People

  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Henriquez, Craig S., Professor of Biomedical Engineering, Biomedical Engineering
  • Malkin, Robert A., Professor of the Practice Emeritus in the Department of Biomedical Engineering, Duke Science & Society
  • Velkey, John Matthew, Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology