Heart Valve Diseases

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  Subject Areas on Research

  • 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 
  • 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 
  • 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 
  • 2016 Annual Report of The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry. 
  • 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. 
  • 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. 
  • 26th Bethesda conference: recommendations for determining eligibility for competition in athletes with cardiovascular abnormalities. Task Force 2: acquired valvular heart disease. 
  • 26th Bethesda conference: recommendations for determining eligibility for competition in athletes with cardiovascular abnormalities. Task Force 2: acquired valvular heart disease. 
  • ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2017 Appropriate Use Criteria for Multimodality Imaging in Valvular Heart Disease : A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. 
  • ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2017 Appropriate Use Criteria for Multimodality Imaging in Valvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. 
  • ACR Appropriateness Criteria® Dyspnea-Suspected Cardiac Origin. 
  • Acute myocardial beta-adrenergic receptor dysfunction after cardiopulmonary bypass in patients with cardiac valve disease. Duke Heart Center Perioperative Desensitization Group. 
  • An Approach to Improve the Negative Predictive Value and Clinical Utility of Transthoracic Echocardiography in Suspected Native Valve Infective Endocarditis. 
  • An introduction to transoesophageal echocardiography: II. Clinical applications. 
  • Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias. 
  • Animal models of heart failure: a scientific statement from the American Heart Association. 
  • Anticoagulation After Heart Valve Replacement or Transcatheter Valve Implantation. 
  • Antithrombotic therapy after prosthetic cardiac valve implantation: improving postoperative, long-term patient management. Introduction. 
  • Antithrombotic therapy in atrial fibrillation associated with valvular heart disease: a joint consensus document from the European Heart Rhythm Association (EHRA) and European Society of Cardiology Working Group on Thrombosis, endorsed by the ESC Working Group on Valvular Heart Disease, Cardiac Arrhythmia Society of Southern Africa (CASSA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), South African Heart (SA Heart) Association and Sociedad Latinoamericana de Estimulación Cardíaca y Electrofisiología (SOLEACE). 
  • Aortic Dissection in Patients With Bicuspid Aortic Valve-Associated Aneurysms. 
  • Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial. 
  • Aspergillus clavatus endocarditis involving a normal aortic valve following coronary artery surgery. 
  • Assessing housestaff diagnostic skills using a cardiology patient simulator. 
  • Association between indices of prosthesis internal orifice size and operative mortality after isolated aortic valve replacement. 
  • Associations between valve repair and reduced operative mortality in 21,056 mitral/tricuspid double valve procedures. 
  • Atrial fibrillation correction surgery: lessons from the Society of Thoracic Surgeons National Cardiac Database. 
  • Basic diagnostic echocardiography. 
  • Beating-heart mitral valve surgery: preliminary model and methodology. 
  • Bedside tool for predicting the risk of postoperative dialysis in patients undergoing cardiac surgery. 
  • Binding of IgG-sensitized erythrocytes by mitral and aortic cardiac valves: a possible clue to the pathogenesis of immune valvular heart disease. 
  • Calcific valvular aortic stenosis with and without mitral anular calcium. 
  • Calcification of the ascending aorta and aortic and mitral valves in Gaucher's disease. 
  • Carcinoid heart disease. Correlation of high serotonin levels with valvular abnormalities detected by cardiac catheterization and echocardiography. 
  • Cardiac operations in patients with functioning renal allografts. 
  • Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 1. 
  • Classification of community-acquired endocarditis due to coagulase-negative staphylococci. 
  • Clinical and echocardiographic characteristics of patients with mitral anular calcification. Comparison with age- and sex-matched control subjects. 
  • Clinical and hemodynamic results with the St. Jude medical aortic valve prosthesis. 
  • Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya. 
  • Clinical characteristics and outcome of aortic endocarditis with periannular abscess in the International Collaboration on Endocarditis Merged Database. 
  • Clinical characteristics and outcome of infective endocarditis involving implantable cardiac devices. 
  • Clinical characteristics of patients younger than 60 years with mitral anular calcium: comparison with age- and sex-matched control subjects. 
  • Clinical outcomes after implantation of a centrifugal flow left ventricular assist device and concurrent cardiac valve procedures. 
  • Clinical outcomes at 1 year following transcatheter aortic valve replacement. 
  • Combined valvular disease: when echocardiography provides the questions and the answers. 
  • Comparison of direct aortic and femoral cannulation for port-access cardiac operations. 
  • Comparison of port access to sternotomy in tricuspid or mitral/tricuspid operations. 
  • Conduction defects and mitral annulus calcification. 
  • Congenital and Acquired Valvular Heart Disease in Pregnancy. 
  • Contrast-enhanced magnetic resonance imaging identifies focal regions of intramyocardial fibrosis in patients with severe aortic valve disease: Correlation with quantitative histopathology. 
  • Coronary embolism and calcified aortic valve: is there a correlation? 
  • Coronary-Artery Bypass Grafting. 
  • Correlation of cine MR imaging with two-dimensional pulsed Doppler echocardiography in valvular insufficiency. 
  • Current best practices and guidelines. Assessment and management of complications in infective endocarditis. 
  • Daptomycin is effective in treatment of experimental endocarditis due to methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus. 
  • Depression in male and female patients undergoing cardiac surgery. 
  • Detection of persistent left superior vena cava by two-dimensional contrast echocardiography. 
  • Determinants of operative mortality in valvular heart surgery. 
  • Differential diagnosis of pulmonary nodule. 
  • Does Survival on the Heart Transplant Waiting List Depend on the Underlying Heart Disease? 
  • Does mitral valve repair offer an advantage over replacement in patients undergoing aortic valve replacement? 
  • Early surgery in patients with infective endocarditis: a propensity score analysis. 
  • Echocardiographic Assessment of Complete Atrioventricular Canal Defects: A Balancing Act. 
  • Echocardiographic and electrocardiographic characteristics of patients with hypertrophic cardiomyopathy with and without mitral anular calcium. 
  • Echocardiography of the mitral valve. 
  • Effect of fenfluramine-derivative diet pills on cardiac valves: a meta-analysis of observational studies. 
  • Efficacy of the internal mammary artery in combined aortic valve replacement-coronary artery bypass grafting. 
  • Emergence of coagulase-negative staphylococci as a cause of native valve endocarditis. 
  • Epigenetic profiling identifies novel genes for ascending aortic aneurysm formation with bicuspid aortic valves. 
  • Exclusion of mitral valvuloplasty from predictors of mortality for patients undergoing cardiac valve replacements in New York State. 
  • Exercise echocardiographic comparison of pulmonary autograft and aortic homograft replacements for aortic valve disease in adults. 
  • Feasibility of point-of-care echocardiography by internal medicine house staff. 
  • Fifteen-year outcome trends for valve surgery in North America. 
  • First report of the Port Access International Registry. 
  • Fusion of the left aortic cusp to the aoic wall with occlusion of the left coronary ostium, and aortic stenosis and insufficiency. 
  • Gender differences in mortality after mitral valve operation: evidence for higher mortality in perimenopausal women. 
  • Genetic associations with valvular calcification and aortic stenosis. 
  • Global and regional burden of infective endocarditis, 1990-2010: a systematic review of the literature. 
  • Hemodynamic evaluation of glucagon in symptomatic heart disease. 
  • Hemodynamic evaluation of rate augmentation produced by atrial pacing and isoproterenol in the early postoperative phase of cardiac valve surgery. 
  • Imaging techniques for diagnosis of infective endocarditis. 
  • Impact of complications on outcomes following aortic and mitral valve replacements in the United States. 
  • Impact of concurrent surgical valve procedures in patients receiving continuous-flow devices. 
  • Impact of valvular calcification on the diagnostic accuracy of transesophageal echocardiography for the detection of congenital aortic valve malformation. 
  • In pursuit of perfection: "alive and better" as the measure of procedural success. 
  • Inclusion of Functional Status Measures in the Risk Adjustment of 30-Day Mortality After Transcatheter Aortic Valve Replacement: A Report From the Society of Thoracic Surgeons/American College of Cardiology TVT Registry. 
  • Increasing healthcare resource utilization after coronary artery bypass graft surgery in the United States. 
  • Individualized thoracic aortic replacement for the aortopathy of biscuspid aortic valve disease. 
  • Infective endocarditis. 
  • Influence of age on outcomes in patients undergoing mitral valve replacement. 
  • Influence of patient age on procedural selection in mitral valve surgery. 
  • Invasive hemodynamic evaluation in patients with mechanical aortic valves. 
  • Invited Commentary. 
  • Invited commentary. 
  • Invited commentary. 
  • It's not just an open or shut case. 
  • Late results after mitral valve replacement with the Björk-Shiley and porcine prostheses. 
  • Late survival after valve operation in patients with left ventricular dysfunction. 
  • Letter: Discovery of paravalvular defects. 
  • Long-Term Clinical Outcomes of Silzone Era St. Jude Medical Mechanical Heart Valves. 
  • Long-Term Survival After Bovine Pericardial Versus Porcine Stented Bioprosthetic Aortic Valve Replacement: Does Valve Choice Matter? 
  • Long-term outcome after biologic versus mechanical aortic valve replacement in 841 patients. 
  • Long-term survival after aortic valve replacement among high-risk elderly patients in the United States: insights from the Society of Thoracic Surgeons Adult Cardiac Surgery Database, 1991 to 2007. 
  • Low dose dopamine infusion reduces renal tubular injury following cardiopulmonary bypass surgery. 
  • Machine-learning phenotypic classification of bicuspid aortopathy. 
  • Maladaptive matrix remodeling and regional biomechanical dysfunction in a mouse model of aortic valve disease. 
  • Massive calcification of the mitral annulus in a 17-year-old patient with juvenile rheumatoid arthritis and systemic lupus erythematosis. 
  • Maternal valvular heart disease in pregnancy. 
  • Minimally Invasive Mitral Repair: Direct Aortic Cannulation Via Right 2nd Intercostal Space. 
  • Minimally invasive tricuspid operation using port access. 
  • Mitral procedure selection in patients on dialysis: does mitral repair influence outcomes? 
  • Mitral valve repair and cardiac transplantation in a patient with factor XII deficiency. 
  • Mitral valve repair for degenerative disease: a 20-year experience. 
  • Mitral valve surgery and acute renal injury: port access versus median sternotomy. 
  • National Trends and Outcomes in Isolated Tricuspid Valve Surgery. 
  • Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the International Collaboration on Endocarditis Merged Database. 
  • Native valve infective endocarditis in elderly and younger adult patients: comparison of clinical features and outcomes with use of the Duke criteria and the Duke Endocarditis Database. 
  • Native valve infective endocarditis in elderly and younger adult patients: comparison of clinical features and outcomes with use of the Duke criteria. 
  • Neglecting enterococci may lead to a misinterpretation of the consequences of last changes in endocarditis prophylaxis American Heart Association guidelines. 
  • Neurological injury after transcatheter aortic valve implantation: are the trees falling silently or is our hearing impaired? 
  • Outcomes After Operations for Unicuspid Aortic Valve With or Without Ascending Repair in Adults. 
  • Outcomes and prosthesis choice for active aortic valve infective endocarditis: analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database. 
  • Outcomes following transcatheter aortic valve replacement in the United States. 
  • Outcomes in anticoagulated patients with atrial fibrillation and with mitral or aortic valve disease. 
  • Outcomes of cardiac surgery in patients > or = 80 years: results from the National Cardiovascular Network. 
  • Periannular complications in infective endocarditis involving native aortic valves. 
  • Periannular complications in infective endocarditis involving prosthetic aortic valves. 
  • Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline. 
  • Personalized cardiac surgery: Can noninvasive flow imaging lead to individualized resection strategies for bicuspid aortopathy? 
  • Post-market surveillance to detect adverse events associated with Melody® valve implantation. 
  • Postdischarge international normalized ratio testing and long-term clinical outcomes of patients with heart failure receiving warfarin: findings from the ADHERE registry linked to Medicare claims. 
  • Predictors of mortality for patients undergoing cardiac valve replacements in New York State. 
  • Prevalence of multivalvular regurgitation in athletes. 
  • Prevalence, Characteristics, and Outcomes of Valvular Heart Disease in Patients With Atrial Fibrillation: Insights From the ORBIT-AF (Outcomes Registry for Better Informed Treatment for Atrial Fibrillation). 
  • Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community. 
  • Prognostic factors in 61 cases of Staphylococcus aureus prosthetic valve infective endocarditis from the International Collaboration on Endocarditis merged database. 
  • Pulmonary Valve Replacement With a Trifecta Valve Is Associated With Reduced Transvalvular Gradient. 
  • Pulmonic Valve Disease: Review of Pathology and Current Treatment Options. 
  • Quality of anticoagulation with warfarin in patients with nonvalvular atrial fibrillation in the community setting. 
  • Quality of life and recovery after cardiac surgery. 
  • Quantitation of left-to-right cardiac shunts with radionuclide angiography. 
  • Quantitative radionuclide angiocardiography for determination of chamber to chamber cardiac transit times. 
  • Quantitative radionuclide angiocardiography in evaluation of cardiac function. 
  • ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. 
  • Real-time volumetric echocardiography: the technology and the possibilities. 
  • Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid. 
  • Regional structure-function relationships in mouse aortic valve tissue. 
  • Regional variation in prosthesis choice for aortic valve replacement in older patients. 
  • Relationship of preoperative antiendotoxin core antibodies and adverse outcomes following cardiac surgery. 
  • Response to: 'Congenital tricuspid valve disease can masquerade as primary idiopathic TR' by Rajpal. 
  • Rest and exercise cardiac output and diffusing capacity assessed by a single slow exhalation of methane, acetylene, and carbon monoxide. 
  • Results of valve replacement with mechanical and biological prostheses in chronic renal dialysis patients. 
  • Rheumatic heart disease and other valvular disorders in women. 
  • Right Minithoracotomy Versus Median Sternotomy for Mitral Valve Surgery: A Propensity Matched Study. 
  • Risk factors for pericardial effusion in native valve infective endocarditis and its influence on outcome. 
  • Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who underwent echocardiography before use of medication. 
  • Risk of Infective Endocarditis in Patients with End Stage Renal Disease. 
  • Risk-adjusted survival after tissue versus mechanical aortic valve replacement: a 23-year assessment. 
  • Robotic Mitral Valve Repair in Older Individuals: An Analysis of The Society of Thoracic Surgeons Database. 
  • Safety and Use of Anticoagulation After Aortic Valve Replacement With Bioprostheses: A Meta-Analysis. 
  • Session highlights from the American College of Cardiology Scientific Sessions: March 29 to April 1, 1998. 
  • Session highlights from the American College of Cardiology Scientific Sessions: March 29 to April 1, 1998. 
  • Shifts in surgical revascularization and valve procedures among Medicare beneficiaries. 
  • Special article: basic perioperative transesophageal echocardiography examination: a consensus statement of the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists. 
  • Spread of excitation from the atrium into thoracic veins in human beings and dogs. 
  • Staphylococcus aureus bacteremia and endocarditis. 
  • Stroke location, characterization, severity, and outcome in mitral vs aortic valve endocarditis. 
  • Structural valve deterioration in mitral replacement surgery: comparison of Carpentier-Edwards supra-annular porcine and perimount pericardial bioprostheses. 
  • Surgery for Aortic Dilatation in Patients With Bicuspid Aortic Valves: A Statement of Clarification From the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. 
  • Surgery for Aortic Dilatation in Patients With Bicuspid Aortic Valves: A Statement of Clarification From the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. 
  • Task Force 3: valvular heart disease. 
  • Ten-year results with the St. Jude Medical prosthesis. 
  • The "ideal" replacement heart valve. 
  • The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. 
  • The Mini Mental State Exam as a predictor of neuropsychological functioning after cardiac surgery. 
  • The Modified Ross Procedure with Prosthetic Graft Wrap Does Not Prevent Autograft Failure. 
  • The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 2--isolated valve surgery. 
  • The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 3--valve plus coronary artery bypass grafting surgery. 
  • The Society of Thoracic Surgeons Isolated Aortic Valve Replacement (AVR) Composite Score: a report of the STS Quality Measurement Task Force. 
  • The Society of Thoracic Surgeons risk model for operative mortality after multiple valve surgery. 
  • The Year in Cardiothoracic and Vascular Anesthesia: Selected Highlights From 2017. 
  • The ballooning mitral valve in patients with the "precordial honk" or "whoop". 
  • The clinical utility of transesophageal echocardiography in patients with left-sided infective endocarditis. 
  • The expanding role of mitral valve repair in triple valve operations: contemporary North American outcomes in 8,021 patients. 
  • The noninvasive localization of ventricular pacing sites by radionuclide phase imaging. 
  • The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS). 
  • The risk of valve surgery for endocarditis in patients with dialysis-dependent renal failure. 
  • The year in cardiovascular surgery. 
  • The year in cardiovascular surgery. 
  • The year in cardiovascular surgery. 
  • Tissue harmonic imaging in echocardiography: better valve imaging, but at what cost? 
  • Transcatheter Valve Replacement for Right-sided Valve Disease in Congenital Heart Patients. 
  • Transesophageal echocardiography and evaluation of valvular heart disease. 
  • Trends and Outcomes of Off-label Use of Transcatheter Aortic Valve Replacement: Insights From the NCDR STS/ACC TVT Registry. 
  • Trends in Drug Use-Associated Infective Endocarditis and Heart Valve Surgery, 2007 to 2017: A Study of Statewide Discharge Data. 
  • Trends in mitral valve surgery in the United States: results from the Society of Thoracic Surgeons Adult Cardiac Surgery Database. 
  • Two dimensional echocardiography in mitral, aortic and tricuspid valve prolapse. The clinical problem, cardiac nuclear imaging considerations and a proposed standard for diagnosis. 
  • Two-dimensional echocardiographic assessment of vegetative endocarditis. 
  • Unexpected Cardiac MRI Findings in Patients Presenting to the Emergency Department for Possible Acute Coronary Syndrome. 
  • Use of surgery in patients with native valve infective endocarditis: results from the International Collaboration on Endocarditis Merged Database. 
  • Value of transthoracic echocardiography in predicting embolic events in active infective endocarditis. Duke Endocarditis Service. 
  • Valve surgery in octogenarians: in-hospital and long-term outcomes. 
  • Valve-in-valve transcatheter aortic valve implantation for degenerated bioprosthetic heart valves. 
  • Valvular Heart Disease Patients on Edoxaban or Warfarin in the ENGAGE AF-TIMI 48 Trial. 
  • Valvular disease. 
  • Valvular heart disease in patients supported with left ventricular assist devices. 
  • Valvular heart disease. 
  • Variation in warfarin thromboprophylaxis after mitral valve repair: does equipoise exist and is a randomized trial warranted? 
  • Vegetations in endocarditis: big is bad, but is there more to it? 
  • Working group on noncoronary cardiovascular disease and exercise in women. 
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  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Barker, Piers Christopher Andrew, Professor of Pediatrics, Pediatrics, Cardiology
  • Brennan, J. Matthew, Associate Professor of Medicine, Medicine, Cardiology
  • Curtis, Lesley H., Professor in Population Health Sciences, Medicine, General Internal Medicine
  • Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic