Hemolytic Plaque Technique

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  Subject Areas on Research

  • Activation of human B lymphocytes. III. Concanavalin A-induced generation of suppressor cells of the plaque-forming cell response of normal human B lymphocytes. 
  • Activation of human B lymphocytes. V. Kinetics and mechanisms of suppression of plaque-forming cell responses by concanavalin A-generated suppressor cells. 
  • Activation of human B lymphocytes. VI. Immunoregulation of antibody production by mitogen-induced and naturally occurring cells in normal individuals. 
  • Activation of human B lymphocytes. X. Heterogeneity of concanavalin A-generated suppressor cells of the pokeweed mitogen-induced plaque-forming cell response of human peripheral blood lymphocytes. 
  • Activation of human B lymphocytes. XIII. Characterization of multiple populations of naturally occurring immunoregulatory cells of polyclonally induced in vitro human B cell function. 
  • Activation of human B lymphocytes. XIV. Characterization of the precursor of the pokeweed mitogen-induced anti-sheep red blood cell plaque-forming cell. 
  • Bone marrow-derived lymphoid cells (B cells): functional depletion with cobra factor and fresh serum. 
  • Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. I. A description of the technique and of methods for the analysis of colonies. 
  • Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. II. Paratope frequencies within the mitogen-selected repertoire. 
  • Conditions for conducting the indirect hemolysis test for detection of antibodies to Brucella abortus. 
  • Effect of adriamycin and Corynebacterium parvum in tumor-bearing mice: modulation of response to sheep red blood cells. 
  • Effects of chronic mild stress on serum complement activity, saccharin preference, and corticosterone levels in Flinders lines of rats. 
  • Emergence of suppressor cells of immunoglobulin synthesis during acute Epstein-Barr virus-induced infectious mononucleosis. 
  • Immune competence of germ-free rats. I. Increased responsiveness to transplantation and other antigens. 
  • Immunoregulatory aberrations in systemic lupus erythematosus. 
  • Interaction of pokeweed mitogen with monocytes in the activation of human lymphocytes. 
  • Isolation and characterization of C4-synthesizing cells from guinea-pig spleen. 
  • Mechanisms of corticosteroid action on lymphocyte subpopulations. IV. Effects of in vitro hydrocortisone on naturally occuring and mitogen-induced suppressor cells in man. 
  • Mechanisms of corticosteroid action on lymphocyte subpopulations. V. Effects of in vivo hydrocortisone on the circulatory kinetics and function of naturally occuring and mitogen-induced suppressor cells in man. 
  • Regulation of the immune response. I. Regulatory cell equilibrium in the "virgin" state. 
  • Regulation of the immune response. II. Concomitant idiotope-specific enhancement and suppression can result in a phenotypically normal response. 
  • Underlying complement deficiency in patients with disseminated gonococcal infection. 
  • Use of a human plaque-forming cell assay to study peripheral blood bursa-equivalent cell activation and excessive suppressor cell activity in humoral immunodeficiency. 
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  Keywords of People

  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Integrative Immunobiology