Hexokinase
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Subject Areas on Research
- Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival.
- Antibodies against the voltage-dependent anion channel (VDAC) and its protective ligand hexokinase-I in children with autism.
- Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1.
- Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.
- Differential metabolic effects of adenovirus-mediated glucokinase and hexokinase I overexpression in rat primary hepatocytes.
- Dysregulation of multiple facets of glycogen metabolism in a murine model of Pompe disease.
- Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology.
- GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release. Relationship to glucokinase activity.
- Glucokinase gene transfer to skeletal muscle of diabetic Zucker fatty rats improves insulin-sensitive glucose uptake.
- Glucose 6-phosphate produced by glucokinase, but not hexokinase I, promotes the activation of hepatic glycogen synthase.
- Glucose metabolism as a target of histone deacetylase inhibitors.
- Glucose metabolism gene variants modulate the risk of pancreatic cancer.
- Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression.
- Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts.
- HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use.
- Handedness of crossover connections in beta sheets.
- LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism.
- Oncogene pathway activation in mammary tumors dictates FDG-PET uptake.
- Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.
- Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids.
- Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans.
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
- Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells.
- RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.
- Reg1p targets protein phosphatase 1 to dephosphorylate hexokinase II in Saccharomyces cerevisiae: characterizing the effects of a phosphatase subunit on the yeast proteome.
- Regulation of overexpressed hexokinases in liver and islet cells.
- Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase.
- SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control.
- Studies of the enzyme hexokinase. IV. The role of sulfhydryl groups.
- Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise.
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Keywords of People
- McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship