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Subject Areas on Research
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Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival.
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Allosteric regulation of type I hexokinase: A site-directed mutational study indicating location of the functional glucose 6-phosphate binding site in the N-terminal half of the enzyme.
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Anabolic function of the type II isozyme of hexokinase in hepatic lipid synthesis.
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Antibodies against the voltage-dependent anion channel (VDAC) and its protective ligand hexokinase-I in children with autism.
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Assignment of hexokinase types 1,2,3 (Hk1,2,3) and glucokinase (Gck) to rat chromosome band 20q11, 4q34, 17q12 and 14q21 respectively, by in situ hybridization.
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Characterization of the rat type III hexokinase gene promoter. A functional octamer 1 motif is critical for basal promoter activity.
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Congenital hemolytic anemias and red cell enzyme deficiencies.
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Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1.
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Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.
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Differential metabolic effects of adenovirus-mediated glucokinase and hexokinase I overexpression in rat primary hepatocytes.
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Dysregulation of multiple facets of glycogen metabolism in a murine model of Pompe disease.
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Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology.
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Expression of two type II-like tumor hexokinase RNA transcripts in cancer cell lines.
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GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release. Relationship to glucokinase activity.
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Glucokinase gene transfer to skeletal muscle of diabetic Zucker fatty rats improves insulin-sensitive glucose uptake.
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Glucose 6-phosphate produced by glucokinase, but not hexokinase I, promotes the activation of hepatic glycogen synthase.
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Glucose metabolism as a target of histone deacetylase inhibitors.
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Glucose metabolism gene variants modulate the risk of pancreatic cancer.
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Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression.
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Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts.
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HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use.
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Handedness of crossover connections in beta sheets.
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Hepatic HKDC1 Expression Contributes to Liver Metabolism.
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Hepatic hexokinase domain containing 1 (HKDC1) improves whole body glucose tolerance and insulin sensitivity in pregnant mice.
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Insulin-like growth factor I induces tumor hexokinase RNA expression in cancer cells.
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LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism.
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Oncogene pathway activation in mammary tumors dictates FDG-PET uptake.
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Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.
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Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids.
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Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans.
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Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
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Phosphoglycerate kinase-triose-phosphate isomerase complex from Thermotoga neapolitana.
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Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells.
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RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.
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Reg1p targets protein phosphatase 1 to dephosphorylate hexokinase II in Saccharomyces cerevisiae: characterizing the effects of a phosphatase subunit on the yeast proteome.
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Regulation of overexpressed hexokinases in liver and islet cells.
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Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase.
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SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control.
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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.
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Stimulation of brain hexokinase gene expression by recombinant brain insulin-like growth factor in C6 glial cells.
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Studies of the enzyme hexokinase. IV. The role of sulfhydryl groups.
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Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise.
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The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution.
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Keywords of People