Histocytochemistry

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  Subject Areas on Research

  • 3-Dimensional visualization of lesions in rat brain using magnetic resonance imaging microscopy. 
  • 4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors. 
  • A fixative for use in muscle histochemistry. 
  • A projection from the parabigeminal nucleus to the pulvinar nucleus in Galago. 
  • A rapidly dividing human medulloblastoma cell line (D283 MED) expresses all three neurofilament subunits. 
  • A retroperitoneal bronchogenic cyst. 
  • Absence of estrogen receptor in human melanoma as evaluated by a monoclonal antiestrogen receptor antibody. 
  • Accuracy of fibroscan, compared with histology, in analysis of liver fibrosis in patients with hepatitis B or C: a United States multicenter study. 
  • Alpha-1-antitrypsin globules in hepatocytes of elderly persons with liver disease. 
  • Altered distribution of choline acetyltransferase and acetylcholinesterase activities in the developing rat dentate gyrus following entorhinal lesion. 
  • Alternative method for quantitative enzyme histochemistry of muscle fibers. Application of photographic densitometry combined with atomic absorption spectrophotometry. 
  • Amicrobial Pustulosis of the Folds and Autoimmunity. 
  • Anal-rectal cytology: correlation with human papillomavirus status and biopsy diagnoses in a population of HIV-positive patients. 
  • Anti-c-myc DNA increases differentiation and decreases colony formation by HL-60 cells. 
  • Antiretroviral therapy and the kidney. 
  • Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue. 
  • Are metaplasias in colorectal adenomas truly metaplasias? 
  • Association between puberty and features of nonalcoholic fatty liver disease. 
  • Atypical myosin heavy chain in rat laryngeal muscle. 
  • Barbiturate and GABA receptors coupled to benzodiazepine receptors in rat hippocampal formation: a radiohistochemical study. 
  • Basal linear deposit in the human macula. 
  • Biochemical approaches to dementia. 
  • Biochemical plasticity of short-axon interneurons: increased glutamate decarboxylase activity in the denervated area of rat dentate gyrus following entorhinal lesion. 
  • Biology of hepatocellular neoplasia in the mouse. II. Sequential enzyme histochemical analysis of BALB/c mouse liver during safrole-induced carcinogenesis. 
  • Bmp4 is required for the generation of primordial germ cells in the mouse embryo. 
  • Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors. 
  • Brain gene regulation by territorial singing behavior in freely ranging songbirds. 
  • Brain tumors in man and animals: report of a workshop. 
  • C-reactive protein activates the nuclear factor-kappaB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis. 
  • Candidate counterparts of Sézary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: an ultrastructural study with the immunogold method and monoclonal antibodies. 
  • Canine model and genomic structural organization of glycogen storage disease type Ia (GSD Ia). 
  • Carbohydrate histochemistry of surface epithelium of rat trachea: backscatter and x-ray imaging. 
  • Cell proliferation contributes to PNEC hyperplasia after acute airway injury. 
  • Centronuclear myopathy: histochemistry and electron microscopy. Report of two cases. 
  • Cholesterol-fed and casein-fed rabbit models of atherosclerosis. Part 2: Differing morphological severity of atherogenesis despite matched plasma cholesterol levels. 
  • Clinical response to hormone therapy correlated with estrogen receptor analyses. Biochemical v histochemical methods. 
  • Clinical utility of cardiac valve Gram stain and culture in patients undergoing native valve replacement. 
  • Clinicopathologic and genetic spectrum of infantile B-lymphoblastic leukemia: a multi-institutional study. 
  • Clinicopathologic correlations in the oligodendroglioma. 
  • Collagen changes in rat cervix in pregnancy--polarized light microscopic and electron microscopic studies. 
  • Collagen fibril diameters in arteries of mice. A comparison of manual and computer-aided morphometric analyses. 
  • Comorbidity of age-related macular degeneration with Alzheimer's disease: A histopathologic case-control study. 
  • Comparative toxicity of polychlorinated biphenyl and polybrominated biphenyl in the rat liver: light and electron microscopic alterations after subacute dietary exposure. 
  • Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2. 
  • Conclusive evidence for the presence of elastin in human and monkey cervix. 
  • Continuous human glioma-derived cell lines UC-11MG and UC-302MG. Morphologic, immunocytochemical and chromosomal characterization. 
  • Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study. 
  • Correlation of FIBROSpect II with histologic and morphometric evaluation of liver fibrosis in chronic hepatitis C. 
  • Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo. 
  • Cytochemistry of sex steroid receptors: a critique. 
  • Cytologic studies of glucose-6-phosphate dehydrogenase in malignancy. 
  • Deconstructing Pompe disease by analyzing single muscle fibers: to see a world in a grain of sand... 
  • Decreased IGF-I gene expression during the apoptosis of Purkinje cells in pcd mice. 
  • Deficiency of double-strand DNA break repair does not impair Mycobacterium tuberculosis virulence in multiple animal models of infection. 
  • Degradation of the epidermal-dermal junction by proteolytic enzymes from human skin and human polymorphonuclear leukocytes. 
  • Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice. 
  • Development of cholinergic innervation in the hippocampal formation of the rat. I. Histochemical demonstration of acetylcholinesterase activity. 
  • Developmental and regional differences in the localization of Na,K-ATPase activity in the rabbit hippocampus. 
  • Diagnosing Liver Fibrosis and Cirrhosis: Serum, Imaging, or Tissue? 
  • Diagnosis of diffuse malignant mesothelioma: experience of a US/Canadian Mesothelioma Panel. 
  • Differentiated Vulvar Intraepithelial Neoplasia: What Criteria Do We Use in Practice? 
  • Disorders of cell volume regulation. I. Effects of inhibition of plasma membrane adenosine triphosphatase with ouabain. 
  • Distribution of GABAA receptors in the limbic system of alcohol-preferring and non-preferring rats: in situ hybridisation histochemistry and receptor autoradiography. 
  • Distribution of acetylcholinesterase in the geniculo striate system of Galago senegalensis and Aotus trivirgatus: evidence for the origin of the reaction product in the lateral geniculate body. 
  • Distribution of opioid peptide gene expression in the limbic system of Fawn-Hooded (alcohol-preferring) and Wistar-Kyoto (alcohol-non-preferring) rats. 
  • Distributions of choline acetyltransferase and acetylcholinesterase activities in the retinal layers of the red-tailed hawk and road runner. 
  • Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis. 
  • Expression of telomerase reverse transcriptase (TERT) in malignant mesotheliomas. 
  • Extraocular muscle involvement in idiopathic primary amyloidosis. 
  • Eye movements and brainstem neuronal responses evoked by cerebellar and vestibular stimulation in chicks. 
  • Facilitated light microscopic cytochemical diagnosis of acute myelogenous leukemia. 
  • Factors Associated With Persistent Increase in Level of Alanine Aminotransferase in Patients With Chronic Hepatitis B Receiving Oral Antiviral Therapy. 
  • Fetal hippocampal cells grafted to kainate-lesioned CA3 region of adult hippocampus suppress aberrant supragranular sprouting of host mossy fibers. 
  • Fluorescent labeling of dissociated fetal cells for tissue culture. 
  • Functional units in rainbow trout (Salmo gairdneri) liver: I. Arrangement and histochemical properties of hepatocytes. 
  • Gastric ulceration in a patient treated with SIR-spheres. 
  • Gastrointestinal involvement and multiple lymphomatous polyposis in mantle-zone lymphoma. 
  • Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins. 
  • Green fluorescent latex microspheres: a new retrograde tracer. 
  • Growth of the rat somatic sensory cortex and its constituent parts during postnatal development. 
  • Hemolytic anemia and metastatic carcinoma: case report and literature review. 
  • Histochemical characterization of non-neuroendocrine tumors and neuroendocrine cell hyperplasia induced in hamster lung by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone with or without hyperoxia. 
  • Histochemical evidence of altered development of cholinergic fibers in the rat dentate gyrus following lesions. I. Time course after complete unilateral entorhinal lesion at various ages. 
  • Histochemical evidence of altered development of cholinergic fibers in the rat dentate gyrus following lesions. II. Effects of partial entorhinal and simultaneous multiple lesions. 
  • Histochemical localization of the PBAN receptor in the pheromone gland of Heliothis peltigera. 
  • Histochemical observations on melanin in the intestinal ceca of Amblosoma suwaense (Trematoda: Brachylaimidae) metacercariae. 
  • Histopathologic and immunochemical features of lattice corneal dystrophy type III. 
  • Human aortic fibrolipid lesions. Progenitor lesions for fibrous plaques, exhibiting early formation of the cholesterol-rich core. 
  • Human spleen contains phenotypic subsets of macrophages and dendritic cells that occupy discrete microanatomic locations. 
  • Identification of calcium oxalate crystals using alizarin red S stain. 
  • Identification of viral infection by confocal microscopy. 
  • Immune cells in a mouse airway model of obliterative bronchiolitis. 
  • Immune reconstitution syndrome in a patient with disseminated histoplasmosis and steroid taper: maintaining the perfect balance. 
  • Immunohistochemical studies of cell differentiation in a juxtaglomerular tumor. 
  • Inspissation of pancreatic zymogen material in cystic fibrosis. 
  • Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis. 
  • Interlaminar connections of the superior colliculus in the tree shrew. I. The superficial gray layer. 
  • Investigation of phosphoprotein signatures of archived prostate cancer tissue specimens via proteomic analysis. 
  • Isolated and synchronous vulvar granular cell tumors: a clinicopathologic study of 17 cases in 13 patients. 
  • Isolation and characterization of the CYP71D16 trichome-specific promoter from Nicotiana tabacum L. 
  • Isolation and culture of murine primary chondrocytes. 
  • Isolation of human splenic macrophages and lymphocytes by countercurrent centrifugal elutriation. 
  • Kindling and associated mossy fibre sprouting are not affected in mice deficient of NGFI-A/NGFI-B genes. 
  • Laboratory correlates and prognostic significance of granular acute lymphoblastic leukemia in children. A Pediatric Oncology Group study. 
  • Late recurrences of Cushing's disease after initial successful transsphenoidal surgery. 
  • Leukocyte chemotactic activity from oral bacteria. 
  • Light microscopic variation of fiber cell size, shape and ordering in the equatorial plane of bovine and human lenses. 
  • Localization of xanthine oxidase in rat duodenum; fixation of sections instead of blocks. 
  • Longstanding lupus vulgaris with basal cell carcinoma. 
  • Magnetic resonance microscopy and histopathology: comparative approach of bromobenzene-induced hepatotoxicity in the rat. 
  • Metabolic variation among rat lumbosacral alpha-motoneurons. 
  • Microprobe analysis of chlorpromazine pigmentation. 
  • Molecular biology of adrenergic receptors in the rat and frog central nervous system. 
  • Morphologic and functional studies of mouse hepatocytes in primary culture. 
  • Morphologic criteria for the preliminary identification of Fusarium, Paecilomyces, and Acremonium species by histopathology. 
  • Morphological survey of teleost organs important in carcinogenesis with attention to fixation. 
  • Mucosubstance histochemistry in control and acid-stressed epidermis of brown bullhead catfish, Ictalurus nebulosus (LeSueur). 
  • Multiplex protein analysis to determine fibrosis stage and progression in patients with chronic hepatitis C. 
  • Myotonic muscular dystrophy: morphology, histochemistry, and growth characteristics of cultured skin fibroblasts. 
  • Natural history of biologically malignant struma ovarii: analysis of 27 cases with extraovarian spread. 
  • Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy. 
  • Neuroblastoma grafts are noninvasively removed within mouse neocortex by selective laser activation of intracellular photolytic chromophore. 
  • Neurohormonal peptides in ovarian carcinoids: an immunohistochemical study of 81 primary carcinoids and of intraovarian metastases from six mid-gut carcinoids. 
  • Neurotoxicity of carbonyl sulfide in F344 rats following inhalation exposure for up to 12 weeks. 
  • Novel type of proliferating lymphoplasmacytoid cell with a characteristic spotted immunofluorescence pattern. 
  • Nutritional cirrhosis in rheusus monkeys: electron microscopy and histochemistry. 
  • Organophosphate-induced acetylcholinesterase inhibition and embryonic retinal cell necrosis in vivo in the teleost (Oryzias latipes). 
  • PHOSPHOLIPIDS OF THE SEXUAL SEGMENT OF THE KIDNEY OF THE INDIAN HOUSE LIZARD, HEMIDACTYLUS FLAVIVIRIDIS RUPPELL. 
  • Partial hepatectomy and bile duct ligation in rainbow trout (Oncorhynchus mykiss): histologic, immunohistochemical and enzyme histochemical characterization of hepatic regeneration and biliary hyperplasia. 
  • Pathology of human mesothelioma. Etiologic and diagnostic considerations. 
  • Pathway from the zona incerta to the superior colliculus in the rat. 
  • Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis. 
  • Patterns of troponin T expression in mammalian fast, slow and promiscuous muscle fibres. 
  • Peripheral polyneuropathy, high and low molecular weight IgM, and amyloidosis. 
  • Phosphotyrosine and phosphoprotein phosphatase activity of alkaline phosphatase in mineralizing cartilage. 
  • Physiological organization of layer 4 in macaque striate cortex. 
  • Pituitary microadenoma and primary lymphoma of brain associated with hypothalamic invasion. 
  • Plasmacytic or lymphoplasmacytic infiltrate in lymph nodes: Diagnostic approach and differential considerations. 
  • Polypoid tumor of the esophagus. 
  • Preneoplastic and neoplastic lesions of rat hereditary renal cell tumors express markers of proximal and distal nephron. 
  • Promiscuous expression of myosin in myotonic dystrophy. 
  • Pulmonary blastoma: an ultrastructural and histochemical study. 
  • Pulmonary cytology of the acquired immune deficiency syndrome: an analysis of 36 cases. 
  • Radiohistochemical demonstration of NMDA/glycine-channel activation in rat hippocampus. 
  • Receptor-mediated monocytoid differentiation of human promyelocytic cells by tumor necrosis factor: synergistic actions with interferon-gamma and 1,25-dihydroxyvitamin D3. 
  • Significance of complement split product C4d in ABO-compatible liver allograft: diagnosing utility in acute antibody mediated rejection. 
  • Skeletal muscle grafts applied to the heart. A word of caution. 
  • Spindle cell sarcoma of the vulva with myofibroblastic differentiation. 
  • Studies on cellular autophagocytosis. A histochemical study on sequential alterations of mitochondria in the glucagon-induced autophagic vacuoles of rat liver. 
  • Synthesis of alpha 2-macroglobulin by bovine adrenal cortical cell cultures. 
  • Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. 
  • Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss. 
  • Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability. 
  • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. 
  • The diagnostic distinction between malignant mesothelioma of the pleura and adenocarcinoma of the lung as defined by a monoclonal antibody (B72.3). 
  • The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos. 
  • The effects of exposure of articular cartilage to air. A histochemical and ultrastructural investigation. 
  • The immunohistochemical application of three anti-GFAP monoclonal antibodies to formalin-fixed, paraffin-embedded, normal and neoplastic brain tissues. 
  • The lens epithelium contains glial fibrillary acidic protein (GFAP). 
  • The light microscopic demonstration of hydroperoxidase-positive Phi bodies and rods in leukocytes in acute myeloid leukemia. 
  • The nitric oxide synthase inhibitor N(G)-nitro-L-arginine decreases defibrillation-induced free radical generation. 
  • The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila. 
  • The undifferentiated malignant neoplasm. Identification of lymphoma arising in skeletal muscle by immunohistochemical analysis. 
  • The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities. 
  • Tinctorial and morphologic properties distinguishing actinomycosis and nocardiosis. 
  • Tissue and cellular alterations in Asian clam (Potamocorbula amurensis) from San Francisco Bay: toxicological indicators of exposure and effect? 
  • Trafficking of apical proteins into clathrin-coated vesicles isolated from rat renal cortex. 
  • Transfer of molecules from glia to axon in the squid may be mediated by glial vesicles. 
  • Ultrastructural alterations in liver of medaka (Oryzias latipes) exposed to diethylnitrosamine. 
  • Ultrastructural development of the small intestinal mucosa in the embryo and turkey poult: A light and electron microscopy study. 
  • Ultrastructural pathology of melanomalytic glaucoma. 
  • Unilateral multicystic dysplasia in an ectopic kidney. 
  • Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors. 
  • Visualization of neuromuscular junctions over periods of several months in living mice. 
  • Wisteria floribunda lectin is associated with specific cell types in the ventral cochlear nucleus of the gerbil, Meriones unguiculatus. 
  • [Histochemical studies on the medial regions of the brainstem in guinea pigs]. 
  • gamma-Aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study. 
  • gamma-Glutamyl transpeptidase activity in benign and malignant human mammary epithelial lesions. Histochemical evaluation. 
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  Keywords of People

  • Hogan, Brigid L. M., George Barth Geller Distinguished Professor for Research in Molecular Biology, Cell Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology