Hyaluronic Acid

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  Subject Areas on Research

  • 3'UTR shortening of HAS2 promotes hyaluronan hyper-synthesis and bioenergetic dysfunction in pulmonary hypertension. 
  • A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking. 
  • A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding. 
  • A photopolymerized sealant for corneal lacerations. 
  • Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma. 
  • Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis. 
  • Adjacent tissues (cartilage, bone) affect the functional integration of engineered calf cartilage in vitro. 
  • Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells. 
  • Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation. 
  • Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study. 
  • Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study. 
  • Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms? 
  • Brain inositol is a novel stimulator for promoting Cryptococcus penetration of the blood-brain barrier. 
  • Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression. 
  • CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma. 
  • CD19, a response regulator of B lymphocytes, regulates wound healing through hyaluronan-induced TLR4 signaling. 
  • CS-4,6 is differentially upregulated in glial scar and is a potent inhibitor of neurite extension. 
  • Chemical sintering generates uniform porous hyaluronic acid hydrogels 
  • Click by Click Microporous Annealed Particle (MAP) Scaffolds. 
  • Clinical use of hyaluronic acid as a predictor of fibrosis change in hepatitis C. 
  • Cocultures of adult and juvenile chondrocytes compared with adult and juvenile chondral fragments: in vitro matrix production. 
  • Commentary to 'Selective endoscopic treatment of the non-refluxing contralateral ureter prevents new contralateral vesicoureteral reflux'. 
  • Comparing Water Absorption of Food and Drug Administration-Approved Hyaluronic Acid Fillers. 
  • Conformational mechanics, adsorption, and normal force interactions of lubricin and hyaluronic acid on model surfaces. 
  • Correlation of FIBROSpect II with histologic and morphometric evaluation of liver fibrosis in chronic hepatitis C. 
  • Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern 
  • Cyclophosphamide treatment used to manipulate the immune response for the production of monoclonal antibodies. 
  • Cytokine induction of the ability of human monocyte CD44 to bind hyaluronan is mediated primarily by TNF-alpha and is inhibited by IL-4 and IL-13. 
  • DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach 
  • Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. 
  • Degradation of proteoglycan in articular cartilage. 
  • Design and characterization of microporous hyaluronic acid hydrogels for in vitro gene transfer to mMSCs 
  • Design of cell–matrix interactions in hyaluronic acid hydrogel scaffolds 
  • Dextranomer/hyaluronic acid for pediatric vesicoureteral reflux: systematic review. 
  • Diagnostic model of esophageal varices in alcoholic liver disease. 
  • Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis. 
  • ECM production of primary human and bovine chondrocytes in hybrid PEG hydrogels containing type I collagen and hyaluronic acid. 
  • Editorial comment on: The role of endoscopic treatment in the management of grade V primary vesicoureteral reflux. 
  • Effect of hyaluronic acid/chondroitin sulfate on healing of full-thickness tendon lacerations in rabbits. 
  • Efficacy of adhesion barriers. Resorbable hydrogel, oxidized regenerated cellulose and hyaluronic acid. 
  • Encapsulation of PEGylated low-molecular-weight PEI polyplexes in hyaluronic acid hydrogels reduces aggregation 
  • Endoscopic Therapy for High Grade Vesicoureteral Reflux-First Line Therapy or Too Good to be True? 
  • Evaluating an incobotulinumtoxinA and Cohesive Polydensified Matrix® hyaluronic acid filler combination to treat moderate-to-severe periorbital and perioral rhytids. 
  • Evaluation of a panel of non-invasive serum markers to differentiate mild from moderate-to-advanced liver fibrosis in chronic hepatitis C patients. 
  • Evidence against posttranslational glycosylation of rat glucocorticoid receptors. 
  • Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated. 
  • Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. 
  • Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis. 
  • Facial Filler Complications. 
  • Fecal Incontinence: Etiology, Diagnosis, and Management. 
  • Genetic immunization with LYVE-1 cDNA yields function-blocking antibodies against native protein. 
  • Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family. 
  • Histopathological changes associated with dextranomer/hyaluronic acid injection for pediatric vesicoureteral reflux. 
  • Hyaluronan Hydrogels for a Biomimetic Spongiosa Layer of Tissue Engineered Heart Valve Scaffolds. 
  • Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity. 
  • Hyaluronan fragments contribute to the ozone-primed immune response to lipopolysaccharide. 
  • Hyaluronan interactions with innate immunity in lung biology. 
  • Hyaluronan molecular weight distribution is associated with the risk of knee osteoarthritis progression. 
  • Hyaluronic Acid Hydrogel Integrated with Mesenchymal Stem Cell-Secretome to Treat Endometrial Injury in a Rat Model of Asherman's Syndrome. 
  • Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery 
  • Hyaluronic acid based low viscosity hydrogel as a novel carrier for Convection Enhanced Delivery of CAR T cells. 
  • Hyaluronic acid, an accurate serum marker for severe hepatic fibrosis in patients with non-alcoholic fatty liver disease. 
  • Hyaluronidase activity of alveolar macrophages. 
  • Hydrogel Design of Experiments Methodology to Optimize Hydrogel for iPSC-NPC Culture 
  • IFNgamma primes macrophages for inflammatory activation by high molecular weight hyaluronan. 
  • Impact of toll-like receptor 4 deficiency on the response to uterine ischemia/reperfusion in mice. 
  • In vitro culture of human peripheral blood monocytes induces hyaluronan binding and up-regulates monocyte variant CD44 isoform expression. 
  • In vivo downregulation of innate and adaptive immune responses in corneal allograft rejection by HC-HA/PTX3 complex purified from amniotic membrane. 
  • Indocyanine green-loaded nanoparticles for image-guided tumor surgery. 
  • Integrating light-sheet imaging with virtual reality to recapitulate developmental cardiac mechanics 
  • Intracameral Delivery of Layer-by-Layer Coated siRNA Nanoparticles for Glaucoma Therapy. 
  • Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels. 
  • Is the appearance of the dextranomer/hyaluronic acid mound predictive of reflux resolution? 
  • Macroporous Dual-compartment Hydrogels for Minimally Invasive Transplantation of Primary Human Hepatocytes. 
  • Microgel-Assisted Delivery of Adenosine to Accelerate Fracture Healing. 
  • Microporous annealed particle hydrogel stiffness, void space size, and adhesion properties impact cell proliferation, cell spreading, and gene transfer. 
  • Microrheology of hyaluronan solutions: implications for the endothelial glycocalyx. 
  • Middle ear packing: comparison of materials in an animal model of mucosal trauma. 
  • Modified technique for removal of Soemmerring ring and in-the-bag secondary intraocular lens placement in aphakic eyes. 
  • Multivariate comparison of the efficacy of intraureteral versus subtrigonal techniques of dextranomer/hyaluronic acid injection. 
  • N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding. 
  • Non-viral DNA delivery from porous hyaluronic acid hydrogels in mice 
  • Ortho Isomeric Mn(III) N-Alkyl- and Alkoxyalkylpyridylporphyrins-Enhancers of Hyaluronan Degradation Induced by Ascorbate and Cupric Ions. 
  • Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages. 
  • Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells. 
  • Patient-preferred sites of restylane injection in periocular and facial soft-tissue augmentation. 
  • Periocular fillers and related anatomy. 
  • Phosphorylation of the group A Streptococcal CovR response regulator causes dimerization and promoter-specific recruitment by RNA polymerase. 
  • Platelet hyaluronidase-2: an enzyme that translocates to the surface upon activation to function in extracellular matrix degradation. 
  • Porous hyaluronic acid hydrogels for localized nonviral DNA delivery in a diabetic wound healing model 
  • Postoperative ureteral obstruction after subureteral injection of dextranomer/hyaluronic Acid copolymer. 
  • Predicting success in the endoscopic management of pediatric vesicoureteral reflux. 
  • Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. 
  • Procoagulant effects of intraocular sodium hyaluronate (Healon) after phakic diabetic vitrectomy. A prospective, randomized study. 
  • Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis. 
  • Recruited exudative macrophages selectively produce CXCL10 after noninfectious lung injury. 
  • Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies. 
  • Regulation of lung injury and repair by Toll-like receptors and hyaluronan. 
  • Retained Dermal Filler in the Upper Eyelid Masquerading as Periorbital Edema. 
  • Reversing facial fillers: interactions between hyaluronidase and commercially available hyaluronic-acid based fillers. 
  • Review of Periorbital and Upper Face: Pertinent Anatomy, Aging, Injection Techniques, Prevention, and Management of Complications of Facial Fillers. 
  • Role of hyaluronan and hyaluronan-binding proteins in human asthma. 
  • Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using an in vitro matrigel model. 
  • Screening of hyaluronic acid-poly(ethylene glycol) composite hydrogels to support intervertebral disc cell biosynthesis using artificial neural network analysis. 
  • Self-Healing of Hyaluronic Acid to Improve In Vivo Retention and Function. 
  • Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project. 
  • Should intra-articular hyaluronic acid be used routinely for knee osteoarthritis pain? 
  • Single center experience with endoscopic management of vesicoureteral reflux in children. 
  • Surface-and hydrogel-mediated delivery of nucleic acid nanoparticles 
  • Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain 
  • TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. 
  • TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44. 
  • The carbohydrates in frog retinal rod outer segments. 
  • The posterior temporal supraSMAS minimally invasive lifting technique using soft-tissue fillers. 
  • The role of hyaluronan degradation products as innate alloimmune agonists. 
  • The role of hyaluronic acid in atherosclerosis and intimal hyperplasia. 
  • The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels 
  • Three dimensional tubular structure self-assembled by vascular mesenchymal cells at stiffness interfaces of hydrogels 
  • Ultrastructural features of diffuse malignant mesotheliomas. 
  • Unilateral vesicoureteral reflux: does endoscopic injection based on the cystoscopic appearance of the ureteral orifice decrease the incidence of de-novo contralateral reflux? 
  • Utility of dextranomer/hyaluronic acid injection in setting of bladder and ureteral anomalies. 
  • Utilizing cell–matrix interactions to modulate gene transfer to stem cells inside hyaluronic acid hydrogels 
  • Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis. 
  • Variation in osteoarthritis biomarkers from activity not food consumption. 
  • Variation of serum hyaluronan with activity in individuals with knee osteoarthritis. 
  • Viscoelastic response of a model endothelial glycocalyx. 
  • Vocal fold injection as a treatment for glottic insufficiency: pro. 
  • Will we be able to repair osteoarthritic joints? New drugs and surgical techniques for cartilage problems. 
  • hapln1 Defines an Epicardial Cell Subpopulation Required for Cardiomyocyte Expansion During Heart Morphogenesis and Regeneration. 
  • pH-Sensitive nanocarrier assisted delivery of adenosine to treat osteoporotic bone loss. 
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  Keywords of People

  • Routh, Jonathan Charles, Paul H. Sherman, M.D. Distinguished Associate Professor of Surgery, Pediatrics
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics