Hydrazines

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  Subject Areas on Research

  • A longitudinal study of quality of life in advanced non-small cell lung cancer: Cancer and Leukemia Group B (CALGB) 8931. 
  • A phase II evaluation of elesclomol sodium and weekly paclitaxel in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube or primary peritoneal cancer: An NRG oncology/gynecologic oncology group study. 
  • Activity of VNP40101M (Cloretazine) in the treatment of CNS tumor xenografts in athymic mice. 
  • Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells. 
  • Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase. 
  • Cancer cachexia: Are we ready to take a step forward? 
  • Carbohydrate histochemistry of surface epithelium of rat trachea: backscatter and x-ray imaging. 
  • Characterization of glomerular thromboxane receptors in murine lupus nephritis. 
  • Characterization of thromboxane receptor blocking effects of SQ 29548 in the feline pulmonary vascular bed. 
  • Cisplatin, vinblastine, and hydrazine sulfate in advanced, non-small-cell lung cancer: a randomized placebo-controlled, double-blind phase III study of the Cancer and Leukemia Group B. 
  • Clinical results in cachexia therapeutics. 
  • Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors. 
  • Cytogenetic changes induced by 1-(N1-methylhydrazinomethyl)-N-isopropyl benzamide in Ehrlich ascites tumor cells. 
  • Detection of hydrazine, methylhydrazine and isoniazid by capillary electrophoresis with a 4-pyridyl hydroquinone self-assembled microdisk platinum electrode. 
  • Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat. 
  • Electrically conductive "alkylated" graphene paper via chemical reduction of amine-functionalized graphene oxide paper. 
  • Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. 
  • Enantiomeric metabolic interactions and stereoselective human methadone metabolism. 
  • Health-related quality of life and pain with selinexor in patients with advanced dedifferentiated liposarcoma. 
  • Hydrazine sulfate in cancer patients with weight loss. A placebo-controlled clinical experience. 
  • Hyperbaric oxygen reduces cerebral blood flow by inactivating nitric oxide. 
  • Hypoxia modulates nitric oxide-induced regulation of NMDA receptor currents and neuronal cell death. 
  • Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma. 
  • Imine hydrogels with tunable degradability for tissue engineering 
  • Influence of SQ 29,548 on vasoconstrictor responses in the hindquarters vascular bed of the cat. 
  • Influence of SQ 30741 on thromboxane receptor-mediated responses in the feline pulmonary vascular bed. 
  • Initial testing of VNP40101M (Cloretazine) by the pediatric preclinical testing program. 
  • Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials. 
  • KPT-330 Prevents Aortic Valve Calcification via a Novel C/EBPβ Signaling Pathway. 
  • Modulation of thromboxane receptor activation in rat glomerular mesangial cells. 
  • Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity. 
  • Neuroendocrine differentiation is an independent prognostic factor in chemotherapy-treated nonsmall cell lung carcinoma. 
  • Once weekly selinexor, carfilzomib and dexamethasone in carfilzomib non-refractory multiple myeloma patients. 
  • Optimizing a dansylhydrazine (DNSH) based method for measuring airborne acrolein and other unsaturated carbonyls. 
  • Overall survival of patients with triple-class refractory multiple myeloma treated with selinexor plus dexamethasone vs standard of care in MAMMOTH. 
  • Patterning small-molecule biocapture surfaces: microcontact insertion printing vs. photolithography. 
  • Peroxynitrite formation in nitric oxide-exposed submitochondrial particles: detection, oxidative damage and catalytic removal by Mn-porphyrins. 
  • Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program. 
  • Phase I study of temozolomide and laromustine (VNP40101M) in patients with relapsed or refractory leukemia. 
  • Phase I trial of VNP40101M (Cloretazine) in children with recurrent brain tumors: a pediatric brain tumor consortium study. 
  • Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme. 
  • Placebo-controlled randomized study of hydrazine sulfate in lung cancer. 
  • Presynaptic inhibition of dopamine synthesis in rat striatum: effects of chronic dopamine depletion and receptor blockade. 
  • Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation. 
  • Prostacyclin protects against elevated blood pressure and cardiac fibrosis. 
  • Pulmonary alveolar epithelial uptake of S-nitrosothiols is regulated by L-type amino acid transporter. 
  • Regulation of rat hepatic cytochrome P450IIE1 in primary monolayer hepatocyte culture. 
  • Role of growth factors and thrombopoietic agents in the treatment of chronic hepatitis C. 
  • Selinexor for the treatment of patients with previously treated multiple myeloma. 
  • Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial. 
  • Selinexor plus low-dose bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma. 
  • Solvent properties of hydrazine in the preparation of metal chalcogenide bulk materials and films. 
  • Spatially addressable chemoselective C-terminal ligation of an intein fusion protein from a complex mixture to a hydrazine-terminated surface. 
  • The effect of chronic L-dopa administration on supersensitive pre- and postsynaptic dopaminergic receptors in rat brain. 
  • The lipid-rich core region of human atherosclerotic fibrous plaques. Prevalence of small lipid droplets and vesicles by electron microscopy. 
  • Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors. 
  • Thromboxane A2modulates the fibrinolytic system in glomerular mesangial cells. 
  • Thromboxane binding and signal transduction in rat glomerular mesangial cells. 
  • Ultrastructural discrimination of lipid droplets and vesicles in atherosclerosis: value of osmium-thiocarbohydrazide-osmium and tannic acid-paraphenylenediamine techniques. 
  • XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53. 
  • iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors.