Hydrazones
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Subject Areas on Research
- A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation.
- Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones.
- Better late than never: a welcome publication of tardy clinical trial results.
- Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products.
- Chemical Modulation of Endocytic Sorting Augments Adeno-associated Viral Transduction.
- Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury.
- DUCCS and SWANS: when U.S. site-based research was highly successful.
- Dead letter office.
- Effect of levosimendan on survival and adverse events after cardiac surgery: a meta-analysis.
- Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy.
- Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity.
- In vitro and in vivo investigations for the development of cytostatic methylhydrazones.
- Inotropes in the management of acute heart failure.
- Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells.
- Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide.
- LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH).
- Levosimendan in Cardiac Surgery.
- Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery.
- Levosimendan in patients with left ventricular systolic dysfunction undergoing cardiac surgery on cardiopulmonary bypass: Rationale and study design of the Levosimendan in Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass (LEVO-CTS) trial.
- Modifying aroylhydrazone prochelators for hydrolytic stability and improved cytoprotection against oxidative stress.
- On the intractability of estrogen-related receptor alpha as a target for activation by small molecules.
- Pharmacological stimulation of the cholinergic antiinflammatory pathway.
- Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis.
- Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors.
- The disconnect between phase II and phase III trials of drugs for heart failure.
- The role of dynamin in HIV type 1 Env-mediated cell-cell fusion.
- Transport properties of the calcium ionophore ETH-129.
- Two Small Molecules Block Oral Epithelial Cell Invasion by Porphyromons gingivalis.
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Keywords of People
- Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology