Hydrogen-Ion Concentration

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  Subject Areas on Research

  • "Cracked-mud" ciprofloxacin precipitates on a corneal graft. 
  • (i, i + 4) Ion pairs stabilize helical peptides derived from smooth muscle caldesmon. 
  • A calorimetric study of the interaction of ATP with rabbit muscle phosphofructokinase. 
  • A canine model of gastroesophageal reflux disease (GERD). 
  • A comparative study of the effect of arterial and venous occlusion after various periods of ischemia. 
  • A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments. 
  • A device for sampling arterialized earlobe blood in austere environments. 
  • A disrupted homologue of the human CLN3 or juvenile neuronal ceroid lipofuscinosis gene in Saccharomyces cerevisiae: a model to study Batten disease. 
  • A fine line between molecular umbrella transport and ionophoric activity. 
  • A kinetic study of protein-protein interactions. 
  • A kinetic study of the binding of an ADP fluorescent analog to mitochondrial ATPase. 
  • A novel thermostable branching enzyme from an extremely thermophilic bacterial species, Rhodothermus obamensis. 
  • A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. 
  • A pH-sensitive RNA tertiary interaction affects self-cleavage activity of the HDV ribozymes in the absence of added divalent metal ion. 
  • A pH-sensitive, neurogenic pathway mediates disease severity in a model of post-ERCP pancreatitis. 
  • A photolabile ligand for light-activated release of caged copper. 
  • A physicochemical study of fat absorption in rats. Limitation of methods in vitro. 
  • A quantitative fluorescent method for measurement of bacterial adherence and phagocytosis. 
  • A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles. 
  • A rapid capsaicin-activated current in rat trigeminal ganglion neurons. 
  • A rapid fluorescence assay for FtsZ assembly indicates cooperative assembly with a dimer nucleus. 
  • A stable dimer in the pH-induced equilibrium unfolding of the homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT). 
  • A synthetic mimic of the secretory granule for drug delivery. 
  • A vaginal fluid simulant. 
  • A very low-carbohydrate diet improves gastroesophageal reflux and its symptoms. 
  • ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations. 
  • ATP hydrolysis by a CFTR domain: pharmacology and effects of G551D mutation. 
  • Acid-base analysis of individuals following two weight loss diets. 
  • Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria. 
  • Acid-based parameters on pH-impedance testing predict symptom improvement with medical management better than impedance parameters. 
  • Acidic stress promotes a glioma stem cell phenotype. 
  • Acidification of interstitial fluid in hippocampal formation caused by seizures and by spreading depression. 
  • Activated conformers of Escherichia coli sulfite reductase heme protein subunit. 
  • Activation of protein kinase C by oleic acid. Determination and analysis of inhibition by detergent micelles and physiologic membranes: requirement for free oleate. 
  • Activation of the guinea pig granulocyte NAD(P)H-dependent superoxide generating enzyme: localization in a plasma membrane enriched particle and kinetics of activation. 
  • Activity and activation of the granulocyte superoxide-generating system. 
  • Acute effects of ethanol on myocardial blood flow in the nonischemic and ischemic heart. 
  • Acute histologic effects of extraesophageal reflux on vocal fold healing. 
  • Acute tubular necrosis. An experimental model detailing the biochemical events accompanying renal injury and recovery. 
  • Addressing biological uncertainties in engineering gene circuits. 
  • Affinity chromatography of H+-translocating adenosine triphosphatase isolated by chloroform extraction of Rhodospirillum rubrum chromatophores. Modification of binding affinity by divalent cations and activating anions. 
  • Aggregation of rabbit muscle phosphofructokinase. 
  • Agonist-dependent potentiation of vanilloid receptor transient receptor potential vanilloid type 1 function by stilbene derivatives. 
  • Alkali action on the urinary crystallization of calcium salts: contrasting responses to sodium citrate and potassium citrate. 
  • Alkaline low spin form of sulfite reductase hemeprotein subunit. 
  • Alkaline ribonuclease in rat liver: effect of hypophysectomy and fasting. 
  • Allostery in Callinectes sapidus hemocyanin: cooperative oxygen binding and interactions with L-lactate, calcium, and protons. 
  • Altered interaction of Cis-dichlorodiammineplatinum(II)--modified alpha 2-macroglobulin (alpha 2M) with the low density lipoprotein receptor-related protein/alpha 2M receptor but not the alpha 2M signaling receptor. 
  • Ambulatory pH monitoring in the management of reflux. 
  • Aminopyridines and sparteine as inhibitors of membrane potassium conductance: effects on Myxicola giant axons and the lobster neuromuscular junction. 
  • Amiodarone-liposome interaction: a multinuclear NMR and X-ray diffraction study. 
  • Amperometric glucose biosensor based on lipid film. 
  • Amphitrite ornata erythrocruorin. II. Molecular controls of function. 
  • An evaluation of the effect of methylene blue dye pH on apical leakage. 
  • Analysis of pH gradients resulting from mass transport limitations in engineered heart tissue. 
  • Analysis of quinolizidine alkaloids in Sophora flavescens Ait. by capillary electrophoresis with tris(2,2'-bipyridyl) ruthenium (II)-based electrochemiluminescence detection. 
  • Analysis of the effect of three different allosteric ligands on oxygen binding by hemocyanin of the shrimp, Penaeus setiferus. 
  • Anesthetic technique for cesarean delivery and neonatal acid-base status: a retrospective database analysis. 
  • Angiostatin is directly cytotoxic to tumor cells at low extracellular pH: a mechanism dependent on cell surface-associated ATP synthase. 
  • Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase. 
  • Anion modulation of the negative Bohr effect of haemoglobin from a primitive amphibian. 
  • Antennal hair erection in male mosquitoes: a new mechanical effector in insects. 
  • Antiarrhythmic drug action. Blockade of the inward sodium current. 
  • Apical and basolateral endocytic pathways of MDCK cells meet in acidic common endosomes distinct from a nearly-neutral apical recycling endosome. 
  • Application of the finite difference method to model pH and substrate concentration in a double-chamber microbial fuel cell. 
  • Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver. 
  • Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptors. 
  • Aspiration of gastric fluid in pulmonary allografts: effect of pH. 
  • Assembly and calcium-induced cooperativity of Limulus IV hemocyanin: a model system for analysis of structure-function relationships in the absence of subunit heterogeneity. 
  • Assembly dynamics of Mycobacterium tuberculosis FtsZ. 
  • Assessment of nitric oxide signals by triiodide chemiluminescence. 
  • Association of air pollution sources and aldehydes with biomarkers of blood coagulation, pulmonary inflammation, and systemic oxidative stress. 
  • Astringent-tasting compounds alter ion transport across isolated canine lingual epithelia. 
  • Attenuation of acid induced oesophagitis in VR-1 deficient mice. 
  • BACPTDP: a water-soluble camptothecin pro-drug with enhanced activity in hypoxic/acidic tumors. 
  • Bacterial community responses to a gradient of alkaline mountaintop mine drainage in Central Appalachian streams. 
  • Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. 
  • Bacterial vaginosis: diagnostic and pathogenetic findings during topical clindamycin therapy. 
  • Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons. 
  • Basic matrices for the matrix-assisted laser desorption/ionization mass spectrometry of proteins and oligonucleotides. 
  • Binding of native and reduced and carbamidomethylated hGH to rabbit liver plasma membranes. 
  • Binding of phosphate ligands to ribonuclease A. 
  • Bioaccessibility testing of cobalt compounds. 
  • Biochemical characterization of the human copper transporter Ctr1. 
  • Biochemical profile of stone-forming patients with diabetes mellitus. 
  • Biochemical properties of oncornavirus polypeptides. 
  • Biophysical and ultrastructural characterization of adeno-associated virus capsid uncoating and genome release. 
  • Bisulfite induces tandem double CC-->TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination. 
  • Blastomyces dermatitidis chemotactic factor: kinetics of production and biological characterization evaluated by a modified neutrophil chemotaxis assay. 
  • Bovine hepatic fructose 1,6-diphosphatase: -glycerophosphate hydrolysis-evidence for a shared active site. 
  • Brain ligatin: a membrane lectin that binds acetylcholinesterase. 
  • Brain resuscitation. Medical management and innovations. 
  • Brainstem bilirubin toxicity in the newborn primate may be promoted and reversed by modulating PCO2. 
  • CD8+ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from beta-chemokines. 
  • CE coupling with end-column electrochemiluminescence detection for chiral separation of disopyramide. 
  • CO binding by hemocyanins of Limulus polyphemus, Busycon carica, and Callinectes sapidus. 
  • Cadmium(II) removal by a hyperaccumulator fungus Phoma sp. F2 isolated from blende soil. 
  • Calcium release from pituitary secretory granules: modulation by thiols, disulfides, and dihydropyridine calcium channel blockers. 
  • Calcium stone disease: an overview. 
  • Calorimetric determination of the standard transformed enthalpy of a biochemical reaction at specified pH and pMg. 
  • Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient. 
  • Camptothecin analogues with enhanced antitumor activity at acidic pH. 
  • Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread. 
  • Capillary electrophoresis with electrochemiluminescence detection for measurement of aspartate aminotransferase and alanine aminotransferase activities in biofluids. 
  • Capillary electrophoresis with solid-state electrochemiluminescence detector. 
  • Capsaicin, acid and heat-evoked currents in rat trigeminal ganglion neurons: relationship to functional VR1 receptors. 
  • Carbodiimide-mediated coupling of benzenepentacarboxylate to human hemoglobin: structural and functional consequences. 
  • Cardiac and muscle fatigue due to relative functional overload induced by excessive stimulation, hypersensitive excitation-contraction coupling, or diminished performance capacity correlates with sarcoplasmic reticulum failure. 
  • Carrier-facilitated bulk liquid membrane transport of iron(III)-siderophore complexes utilizing first coordination sphere recognition. 
  • Catalytic microcontact printing on chemically functionalized H-terminated silicon. 
  • Catalytic properties of the HhaII restriction endonuclease. 
  • Catalytic scavenging of peroxynitrite by isomeric Mn(III) N-methylpyridylporphyrins in the presence of reductants. 
  • Catechol O-methyltransferase in red blood cells of schizophrenic, depressed, and normal human subjects. 
  • Cathepsin B1. A lysosomal enzyme that degrades native collagen. 
  • Cathepsin D of rabbit skin: an immunoenzymic study. 
  • Caution about overinterpretation of symptom indexes in reflux monitoring for refractory gastroesophageal reflux disease. 
  • Cell permeable fluorescent receptor for detection of H2PO4(-) in aqueous solvent. 
  • Cell surface F1Fo ATP synthase: a new paradigm? 
  • Cell wall mannan and cell surface hydrophobicity in Candida albicans serotype A and B strains. 
  • Cerebral autoregulation during moderate hypothermia in rats. 
  • Cerebral blood flow and oxygen delivery during hypoxemia and hemodilution: role of arterial oxygen content. 
  • Cerebrovascular adaptation to prolonged halothane anesthesia is not related to cerebrospinal fluid pH. 
  • Characteristics of cystine uptake by cultured LLC-PK1 cells. 
  • Characterization of additional components of the environmental pH-sensing complex in the pathogenic fungus Cryptococcus neoformans. 
  • Characterization of constitutive exocytosis in the yeast Saccharomyces cerevisiae. 
  • Characterization of inactive renin from human kidney and plasma. Evidence of a renal source of circulating inactive renin. 
  • Characterization of nuclear angiotensin-II-binding sites in rat liver and comparison with plasma membrane receptors. 
  • Characterization of prolidase activity using capillary electrophoresis with tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence detection and application to evaluate collagen degradation in diabetes mellitus. 
  • Characterization of purified rabbit uterine renin: influence of pregnancy on uterine inactive renin. 
  • Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation. 
  • Characterization of the effects of endotoxin on macrophage tumor cell killing. 
  • Characterization of the interaction between alpha2-macroglobulin and fibroblast growth factor-2: the role of hydrophobic interactions. 
  • Characterization of the ionizable groups interacting with anionic allosteric effectors of human hemoglobin. 
  • Characterization of the role of the amino-terminal proline in the enzymatic activity catalyzed by macrophage migration inhibitory factor. 
  • Characterizing RNA Excited States Using NMR Relaxation Dispersion. 
  • Characterizing reactive oxygen generation and bacterial inactivation by a zerovalent iron-fullerene nano-composite device at neutral pH under UV-A illumination. 
  • Chemical aspects of siderophore mediated iron transport. 
  • Chemical rescue, multiple ionizable groups, and general acid-base catalysis in the HDV genomic ribozyme. 
  • Chloride and pH dependence of cooperative interactions in Limulus polyphemus hemocyanin. 
  • Chloride masks effects of opposing positive charges in Hb A and Hb Hinsdale (beta 139 Asn-->Lys) that can modulate cooperativity as well as oxygen affinity. 
  • Chorda tympani and lingual nerve responses to astringent compounds in rodents. 
  • Cimetidine versus antacids in the prevention of stress erosions in critically ill patients. 
  • Clinical and biochemical presentation of gouty diathesis: comparison of uric acid versus pure calcium stone formation. 
  • Cloning and characterization of vmaA, the gene encoding a 69-kDa catalytic subunit of the vacuolar H+-ATPase during alkaline pH mediated growth of Aspergillus oryzae. 
  • Collagenase in bone of man. 
  • Colloid osmotic pressure of steer crystallins: implications for the origin of the refractive index gradient and transparency of the lens. 
  • Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours. 
  • Comparative properties of channel catfish (Ictalurus punctatus) and blue crab (Callinectes sapidus) acetylcholinesterases. 
  • Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit. 
  • Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease. 
  • Comparison of manufactured and black carbon nanoparticle concentrations in aquatic sediments. 
  • Comparison of various hemoglobin polyoxyethylene conjugate solutions as resuscitative fluids after hemorrhagic shock. 
  • Compatibility of aminophylline and verapamil in intravenous admixtures. 
  • Competition in oxygen-linked anion binding to normal and variant human hemoglobins. 
  • Concentration of carbon dioxide, interstitial pH and synaptic transmission in hippocampal formation of the rat. 
  • Concentration-dependent effects of anions on the anaerobic oxidation of hemoglobin and myoglobin. 
  • Concurrent aggregation and deposition of TiO2 nanoparticles in a sandy porous media. 
  • Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide. 
  • Conformational changes of beta-lactoglobulin induced by anionic phospholipid. 
  • Continuous arterial and venous blood gas monitoring during cardiopulmonary bypass. 
  • Coupled sodium-calcium transport in cultured chick heart cells. 
  • Crystallization and preliminary X-ray crystallographic investigations on several thermostable forms of a Bacillus subtilis lipase. 
  • Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning. 
  • Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells. 
  • Cysteine-rich regions of pig gastric mucin contain von willebrand factor and cystine knot domains at the carboxyl terminal(1). 
  • Cysteines in the transmembrane region of major histocompatibility complex antigens are fatty acylated via thioester bonds. 
  • Cytochrome P450 2C9 plays an important role in the regulation of exercise-induced skeletal muscle blood flow and oxygen uptake in humans. 
  • Cytochrome c oxidase binding of hydrogen peroxide. 
  • Cytosolic delivery of macromolecules 4. Head group-dependent membrane permeabilization by pH-sensitive detergents. 
  • Cytosolic delivery of macromolecules. II. Mechanistic studies with pH-sensitive morpholine lipids. 
  • Cytosolic delivery of macromolecules: I. Synthesis and characterization of pH-sensitive acyloxyalkylimidazoles. 
  • Deep Impact: Effects of Mountaintop Mining on Surface Topography, Bedrock Structure, and Downstream Waters. 
  • Degradation and resilience in Louisiana salt marshes after the BP-Deepwater Horizon oil spill. 
  • Degradation of collagen by a human granulocyte collagenolytic system. 
  • Degradation of proteoglycan in articular cartilage. 
  • Dehydration and delayed proton equilibria of red blood cells suspended in isosmotic phosphate buffers. Implications for studies of sickled cells. 
  • Deposition of silver nanoparticles in geochemically heterogeneous porous media: predicting affinity from surface composition analysis. 
  • Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate. 
  • Detecting solvent-driven transitions of poly(A) to double-stranded conformations by atomic force microscopy. 
  • Detection of hydrazine, methylhydrazine and isoniazid by capillary electrophoresis with a 4-pyridyl hydroquinone self-assembled microdisk platinum electrode. 
  • Determination of ranitidine in urine by capillary electrophoresis-electrochemiluminescent detection. 
  • Determination of the stoichiometry of electron uptake and the midpoint reduction potentials of milk xanthine oxidase at 25 degrees C by microcoulometry. 
  • Dicoumarol-sensitive NADPH: phenanthrenequinone oxidoreductase in channel catfish (Ictalurus punctatus). 
  • Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology. 
  • Differential developmental toxicity of naphthoic acid isomers in medaka (Oryzias latipes) embryos. 
  • Differential localization of placental extracellular superoxide dismutase as pregnancy progresses. 
  • Differential sensitivity to intracellular pH among high- and low-threshold Ca2+ currents in isolated rat CA1 neurons. 
  • Dilution of microbicide gels with vaginal fluid and semen simulants: effect on rheological properties and coating flow. 
  • Dipeptidyl peptidase IV (DPP IV/CD26) is a cell-surface plasminogen receptor. 
  • Direct electrochemistry of hemoglobin in egg-phosphatidylcholine films and its catalysis to H(2)O(2). 
  • Direct tris(2,2'-bipyridyl)ruthenium (II) electrochemiluminescence detection of polyamines separated by capillary electrophoresis. 
  • Discovery and characterization of human antibody inhibitors of pregnancy-associated plasma protein-A. 
  • Discovery of protein- and DNA-imperceptible nanoparticle hard coating using gel-based reaction tuning. 
  • Distal mean nocturnal baseline impedance on pH-impedance monitoring predicts reflux burden and symptomatic outcome in gastro-oesophageal reflux disease. 
  • Dog inactive renin: biochemical characterization and secretion into renal plasma and lymph. 
  • Dual-specific Cdc25B phosphatase: in search of the catalytic acid. 
  • Dynamic basis for dG•dT misincorporation via tautomerization and ionization. 
  • Dynamics of the helix--coil transition in poly-L-ornithine. 
  • ELEMENTARY STEPS IN ENZYME REACTIONS (AS STUDIED BY RELAXATION SPECTROMETRY). 
  • EPR spectroscopy of nitrite complexes of methemoglobin. 
  • Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction. 
  • Effect of hyperbaric oxygenation on left ventricular function. 
  • Effect of acidosis on glutamine transport by isolated rat renal brush-border and basolateral-membrane vesicles. 
  • Effect of alpha(alpha)-cross-linked hemoglobin and pyridoxalated hemoglobin polyoxyethylene conjugate solutions on gastrointestinal regional perfusion in hemorrhagic shock. 
  • Effect of carbon dioxide on human ovarian carcinoma cell growth. 
  • Effect of different coffees on esophageal acid contact time and symptoms in coffee-sensitive subjects. 
  • Effect of fluorocarbon-for-blood exchange on regional cerebral blood flow in rats. 
  • Effect of heme and non-heme ligands on subunit dissociation of normal and carboxypeptidase-digested hemoglobin. Gel filtration and flash photolysis studies. 
  • Effect of oxygen and allosteric effects on structural stability of oligomeric hemocyanins of the arthropod, Limulus polyphemus, and the mollusc, Helix pomatia. 
  • Effect of pH and anions on functional properties of hemoglobin from Lemur fulvus fulvus. 
  • Effect of pH on the microhardness of renal calculi. 
  • Effect of pH-adjustment of bupivacaine on onset and duration of epidural analgesia in parturients. 
  • Effect of pulmonary surfactant on the dissolution, stability and uptake of zinc oxide nanowires by human respiratory epithelial cells. 
  • Effect of serotonin on internal and external carotid artery blood flow in the baboon. 
  • Effect of steady illumination on the binding of carbon monoxide by carboxymethylated cytochrome c. 
  • Effect of temperature and pH on contraceptive gel viscosity. 
  • Effect of temperature during cardiopulmonary bypass on gastric mucosal perfusion. 
  • Effects of 10-hydroxycamptothecin, delivered from locally injectable poly(lactide-co-glycolide) microspheres, in a murine human oral squamous cell carcinoma regression model. 
  • Effects of acid-stress on epidermal mucous cells of the brown bullhead Ictalurus nebulosus (LeSeur): a morphometric study. 
  • Effects of age and exercise on physiological dead space during simulated dives at 2.8 ATA. 
  • Effects of amiloride on pH regulation in canine cardiac Purkinje fibers. 
  • Effects of heavy metals on the respiratory proteins of marine organisms in relation to environmental pollution. 
  • Effects of hyperoxia on ventilation and pulmonary hemodynamics during immersed prone exercise at 4.7 ATA: possible implications for immersion pulmonary edema. 
  • Effects of pH and medullary blood flow on oxygen transport and sodium reabsorption in the rat outer medulla. 
  • Efficient sporulation of yeast in media buffered near pH6. 
  • Electrochemical activation of electrodes for amperometric detection of nitric oxide. 
  • Electrochemiluminescence detection with integrated indium tin oxide electrode on electrophoretic microchip for direct bioanalysis of lincomycin in the urine. 
  • Electron paramagnetic resonance of the tungsten derivative of rat liver sulfite oxidase. 
  • Electron paramagnetic resonance properties and oxidation-reduction potentials of the molybdenum, flavin, and iron-sulfur centers of chicken liver xanthine dehydrogenase. 
  • Electrostatic Energetics of Bacillus subtilis Ribonuclease P Protein Determined by Nuclear Magnetic Resonance-Based Histidine pKa Measurements. 
  • Electrostatic recognition between superoxide and copper, zinc superoxide dismutase. 
  • Elementary steps in the reaction mechanism of chicken liver fatty acid synthase. Acylation of specific binding sites. 
  • Elementary steps in the reaction mechanism of chicken liver fatty acid synthase. pH dependence of NADPH binding and isotope rate effect for beta-ketoacyl reductase. 
  • Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease: A randomized, sham-controlled trial. 
  • Energetic contribution of non-essential 5' sequence to catalysis in a hepatitis delta virus ribozyme. 
  • Environmental and anthropogenic controls over bacterial communities in wetland soils. 
  • Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917. 
  • Environmental impacts of the coal ash spill in Kingston, Tennessee: an 18-month survey. 
  • Erosion of microbicide formulation coating layers: effects of contact and shearing with vaginal fluid or semen. 
  • Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury. 
  • Evaluating pH-induced gastrointestinal aggregation of Arachis hypogaea 1 fragments as potential components of peanut allergy. 
  • Evaluation of a sol-gel derived carbon composite electrode as an amperometric detector for capillary electrophoresis. 
  • Evidence for polymorphonuclear-leucocyte-derived proteinases in arthritic cartilage. 
  • Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport. 
  • Evolution of adverse changes in stored RBCs. 
  • Exploitation of intracellular pH gradients in the cellular delivery of macromolecules. 
  • Exploring the role of pH in modulating the effects of lidocaine in virtual ischemic tissue. 
  • Expression of spinach glycolate oxidase in Saccharomyces cerevisiae: purification and characterization. 
  • Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy. 
  • Extracellular pH modulates block of both sodium and calcium channels by nicardipine. 
  • Extracorporeal shock wave lithotripsy: the use of chemical treatments for improved stone comminution. 
  • Extraction and identification by mass spectrometry of undecaprenyl diphosphate-MurNAc-pentapeptide-GlcNAc from Escherichia coli. 
  • Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells. 
  • Fabrication of elastin-like polypeptide nanoparticles for drug delivery by electrospraying. 
  • Factors associated with survival in pediatric extracorporeal membrane oxygenation--a single-center experience. 
  • Factors influencing nonoxynol-9 permeation and bioactivity in cervical mucus. 
  • Farnesylation of nonpeptidic thiol compounds by protein farnesyltransferase. 
  • Fe(III)-complexes of the tripodal trishydroxamate siderophore basidiochrome: potential biological implications. 
  • Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. 
  • Fish brain cholinesterase: its inhibition by carbamates and automatic assay. 
  • Folate-targeted pH-responsive calcium zoledronate nanoscale metal-organic frameworks: Turning a bone antiresorptive agent into an anticancer therapeutic. 
  • Formulations which increase the size of lipoplexes prevent serum-associated inhibition of transfection. 
  • Free sphingosine formation from endogenous substrates by a liver plasma membrane system with a divalent cation dependence and a neutral pH optimum. 
  • Fullerol cluster formation in aqueous solutions: implications for environmental release. 
  • Functional analysis of the calcineurin-encoding gene cnaA from Aspergillus oryzae: evidence for its putative role in stress adaptation. 
  • Functional and structural properties of Murex fulvescens hemocyanin: isolation of two different subunits required for reassociation of a molluscan hemocyanin. 
  • Functional differences in the multiple hemocyanins of the horseshoe crab, Limulus polyphemus L. 
  • Functional photoacoustic microscopy of pH. 
  • Functional properties of carboxypeptidase-digested hemoglobins. 
  • Functional properties of hemoglobin Pôrto Alegre (alpha2A beta2 9Ser leads to Cys) and the reactivity of its extra cysteinyl residue. 
  • Functional properties of normal and sickle cell hemoglobins in polyethylene glycol 6000. 
  • Functional reconstitution of purified human Hv1 H+ channels. 
  • Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation. 
  • Future directions in hyperthermia biology. 
  • Gastroesophageal reflux disease in lung transplant recipients. 
  • Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity. 
  • Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase. 
  • Glutamine stability in biological tissues evaluated by fluorometric analysis. 
  • Glutathione S-transferase-mediated chlorothalonil metabolism in liver and gill subcellular fractions of channel catfish. 
  • Glycine receptor antagonism. Effects of ACEA-1021 on the minimum alveolar concentration for halothane in the rat. 
  • Gossypol: uncoupling of respiratory chain and oxidative phosphorylation. 
  • Growth hormone and prolactin binding to rabbit liver plasma membranes. 
  • Guanidine-induced equilibrium unfolding of a homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT). 
  • H-Ras peptide and protein substrates bind protein farnesyltransferase as an ionized thiolate. 
  • HDV ribozyme activity in monovalent cations. 
  • HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. 
  • Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions. 
  • Heller myotomy versus Heller myotomy with Dor fundoplication for achalasia: a prospective randomized double-blind clinical trial. 
  • Hemocyanin of the chambered nautilus: structure-function relationships. 
  • Hemocyanins in spiders, XIII. Kinetics of oxygen dissociation from individual subunits of Eurypelma and Cupiennius hemocyanin. 
  • Hemoglobin Abruzzo (beta143 (H21) His replaced by Arg). Consequences of altering the 2,3-diphosphoglycerate binding site. 
  • Hemoglobin Deer Lodge (beta 2 His replaced by Arg). Consequences of altering the 2,3-diphosphoglycerate binding site. 
  • Hemoglobin Kansas, a human hemoglobin with a neutral amino acid substitution and an abnormal oxygen equilibrium. 
  • Hemoglobin Raleigh (beta1 valine replaced by acetylalanine). Structural and functional characterization. 
  • Hemoglobin of the electric Atlantic torpedo, Torpedo nobiliana: a cooperative hemoglobin without Bohr effects. 
  • Hemoglobin providence. Functional consequences of two alterations of the 2,3-diphosphoglycerate binding site at position beta 82. 
  • Hemoglobins and hemocyanins: comparative aspects of structure and function. 
  • Hemoglobins of Boa constrictor amarali. 
  • Hemoglobins of the tadpole of the bullfrog, Rana catesbeiana. pH dependence of ligand binding and subunit dissociation equilibria and kinetics. 
  • Hierarchy of RNA functional dynamics. 
  • Human granulocyte collagenase. 
  • Hyaluronidase activity of alveolar macrophages. 
  • Hydrogen peroxide biosensor based on microperoxidase-11 entrapped in lipid membrane. 
  • Hydrolysis of N3-methyl-2'-deoxycytidine: model compound for reactivity of protonated cytosine residues in DNA. 
  • Hydrolysis of methylparathion in soils. 
  • Hyperoxia during reperfusion is a factor in reperfusion injury. 
  • Hypertonic hyperglycemia progresses to diabetes faster than normotonic hyperglycemia. 
  • Hypoxic cell death is reduced by pH buffering in a model of engineered heart tissue. 
  • Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans. 
  • Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist. 
  • Identification of calcium oxalate crystals using alizarin red S stain. 
  • Identification of chloride-binding sites in hemoglobin by nuclear-magnetic-resonance quadrupole-relaxation studies of hemoglobin digests. 
  • Identification of renin and renin-like enzymes in rat brain by a renin-specific antibody. 
  • Identification of the segments of the mouse transferrin receptor 1 required for mouse mammary tumor virus infection. 
  • Images of divalent cations in unstained symmetric and asymmetric lipid bilayers. 
  • Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme. 
  • Immune control of tuberculosis by IFN-gamma-inducible LRG-47. 
  • Immunoinhibition of intracellular protein digestion in macrophages. 
  • Immunological abnormalities in the tears of multiple sclerosis patients. 
  • Impact of renal medullary three-dimensional architecture on oxygen transport. 
  • Improved lung allograft function after fundoplication in patients with gastroesophageal reflux disease undergoing lung transplantation. 
  • In vitro reconstitution of demolybdosulfite oxidase by molybdate. 
  • In vivo measurement of regional brain tissue pH using positron emission tomography. 
  • Inclusion of a nitric oxide congener in the insufflation gas repletes S-nitrosohemoglobin and stabilizes physiologic status during prolonged carbon dioxide pneumoperitoneum. 
  • Induction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy. 
  • Influence of allosteric ligands on the activity and aggregation of rabbit muscle phosphofructokinase. 
  • Influence of lemakalim on the pulmonary vascular bed of the cat. 
  • Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis. 
  • Inhibition of Na+/H+ exchange stimulates CCK secretion in STC-1 cells. 
  • Inhibition of the vacuolar H(+)-pump with bafilomycin A1 does not induce acrosome reaction or activate proacrosin in mouse spermatozoa. 
  • Inhibitory effects of DuP 753 and EXP3174 on responses to angiotensin II in pulmonary vascular bed of the cat. 
  • Insensitivity of Diverse and Temporally Variable Particle-Associated Microbial Communities to Bulk Seawater Environmental Parameters. 
  • Interaction of synthetic HA2 influenza fusion peptide analog with model membranes. 
  • Interactions of nicotinamide adenine dinucleotides with varied states and forms of hemoglobin. 
  • Interconversion of two kinetically distinct states of the membrane-bound and solubilised H+-translocating ATPase from Rhodospirillum rubrum. 
  • Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. 
  • Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. 
  • Intraretinal pH in diabetic cats. 
  • Intravital fluorescence facilitates measurement of multiple physiologic functions and gene expression in tumors of live animals. 
  • Inverse design of molecules with optimal reactivity properties: acidity of 2-naphthol derivatives. 
  • Investigation of noncalcium interactions of fura-2 by classical and synchronous fluorescence spectroscopy. 
  • Investigation of the extraction behavior of the main monoglutamate folates from spinach by liquid chromatography-electrospray ionization tandem mass spectrometry. 
  • Involvement of His HC3 (146) beta in the Bohr effect of human hemoglobin. Studies of native and N-ethylmaleimide-treated hemoglobin A and hemoglobin Cowtown (beta 146 His replaced by Leu). 
  • Involvement of the distal histidine in the low affinity exhibited by Hb Chico (Lys beta 66----Thr) and its isolated beta chains. 
  • Ion regulation in the brain: implications for pathophysiology. 
  • Ionophore 4-BrA23187 transports Zn2+ and Mn2+ with high selectivity over Ca2+. 
  • Iron chelation properties of an extracellular siderophore exochelin MN. 
  • Iron chelation properties of an extracellular siderophore exochelin MS. 
  • Isoflurane for life-threatening bronchospasm: a 15-year single-center experience. 
  • Isolation from the mushroom Agaricus bisporus and chemical synthesis of gamma-L-glutaminyl-4-hydroxybenzene. 
  • Isorenin in dog brain and other tissues. 
  • Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway. 
  • Kinetic and equilibrium studies of the ribonuclease-catalyzed hydrolysis of uridine 2',3'-cyclic phosphate. 
  • Kinetic properties of iodinated ribonuclease A. 
  • Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation. 
  • Kinetic study of collagen fixation with polyepoxy fixatives. 
  • Kinetic study of prolidase activity in erythrocytes against different substrates using capillary electrophoresis with electrochemiluminescence detection. 
  • Kinetics of interaction of disopyramide with the cardiac sodium channel: fast dissociation from open channels at normal rest potentials. 
  • Kinetics of interaction of the lidocaine metabolite glycylxylidide with the cardiac sodium channel. Additive blockade with lidocaine. 
  • Kinetics of nonproteolytic incorporation of a protein ligand into thermally activated alpha 2-macroglobulin: evidence for a novel nascent state. 
  • Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment. 
  • Kinetics of release of serotonin from isolated secretory granules. II. Ion exchange determines the diffusivity of serotonin. 
  • Laparoscopic anti-reflux surgery for idiopathic pulmonary fibrosis at a single centre. 
  • Ligation of the alpha 2-macroglobulin signalling receptor on macrophages induces protein phosphorylation and an increase in cytosolic pH. 
  • Ligation-state hydrogen exchange: coupled binding and folding equilibria in ribonuclease P protein. 
  • Lipid bilayer ultrastructure. Electron density profiles and chain tilt angles as determined by X-ray diffraction. 
  • Lipid membrane immobilized horseradish peroxidase biosensor for amperometric determination of hydrogen peroxide. 
  • Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium. 
  • Lipid-coated microgels for the triggered release of doxorubicin. 
  • Local encoding of computationally designed enzyme activity. 
  • Long-term treatment of calcium nephrolithiasis with potassium citrate. 
  • Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation. 
  • Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells. 
  • Lung disease severity in idiopathic pulmonary fibrosis is more strongly associated with impedance measures of bolus reflux than pH parameters of acid reflux alone. 
  • Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. 
  • MIBG inhibits respiration: potential for radio- and hyperthermic sensitization. 
  • Magnetic resonance water proton relaxation in protein solutions and tissue: T(1rho) dispersion characterization. 
  • Maleylated-BSA induces hydrolysis of PIP2, fluxes of Ca2+, NF-kappaB binding, and transcription of the TNF-alpha gene in murine macrophages. 
  • Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia. 
  • Mas oncogene receptor coupling and peptide specificity in Balb 3T3 and vascular smooth muscle cells. 
  • Maternal insufflation during the second trimester equivalent produces hypercapnia, acidosis, and prolonged hypoxia in fetal sheep. 
  • Measurement and modulation of nonoxynol-9 diffusion and bioactivity against spermatozoa in human cervical mucus. 
  • Mechanical injury to neuronal/glial cultures in microplates: role of NMDA receptors and pH in secondary neuronal cell death. 
  • Metabolic factors associated with endotoxin-induced tolerance for hemorrhagic shock. 
  • Metabolic fate of gossypol: the metabolism of 14C-gossypol in rats. 
  • Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment. 
  • Microcantilever sensing and actuation with end-grafted stimulus-responsive elastin-like polypeptides. 
  • Microencapsulation of 2-octylcyanoacrylate tissue adhesive for self-healing acrylic bone cement. 
  • Mouse mammary tumor virus uses mouse but not human transferrin receptor 1 to reach a low pH compartment and infect cells. 
  • Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA. 
  • Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. 
  • NADPH-dependent oxygen reductase activity in pulmonary macrophages. 
  • NO waiting to exhale in asthma. 
  • Near-infrared optical responses in feline brain and skeletal muscle tissues during respiratory acid-base imbalance. 
  • Neurologic outcomes after coronary artery bypass grafting with and without cardiopulmonary bypass. 
  • Neutral proteinase of rabbit skin: an enzyme capable of degrading skin protein and inducing an inflammatory response. 
  • New insights into the proton-dependent oxygen affinity of Root effect haemoglobins. 
  • New technique for capillary electrophoresis directly coupled with end-column electrochemiluminescence detection. 
  • Nitration of tyrosine by hydrogen peroxide and nitrite. 
  • Noncovalent functionalization of carbon nanotubes by fluorescein-polyethylene glycol: supramolecular conjugates with pH-dependent absorbance and fluorescence. 
  • Noninvasive detection and monitoring of regional myocardial ischemia in situ using depth-resolved 31P NMR spectroscopy. 
  • Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis. 
  • Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. 
  • Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1. 
  • Omeprozole therapy in pediatric patients after liver and intestinal transplantation. 
  • Operational aspects of the desulfurization process of energy gases mimics in biotrickling filters. 
  • Optimization of the lariat ether carboxylic acid host structure for ferrioxamine B: demonstration of a second coordination shell chelate effect. 
  • Organization of skin stratum corneum extracellular lamellae: diffraction evidence for asymmetric distribution of cholesterol. 
  • Oxygen binding by Limulus polyphemus hemocyanin: allosteric modulation by chloride ions. 
  • Oxygen binding domains of Helisoma trivolvis hemoglobin. 
  • Oxygen transport by the circulatory system of the green iguana (Iguana iguana) at different body temperatures. 
  • PH-Dependent effects of quinidine on the kinetics of dV/dtmax in guinea pig ventricular myocardium. 
  • Paroxysmal nocturnal hemoglobinuria. Alternate-complement-pathway-mediated lysis induced by magnesium. 
  • Partial characterization of endogenous phosphorylation conditions for hen brain cytosolic and membrane proteins. 
  • Partial restoration of normal functional properties in carboxypeptidase A-digested hemoglobin. 
  • Particle phase acidity and oligomer formation in secondary organic aerosol. 
  • Pathophysiology of pH and Ca2+ in bloodstream and brain. 
  • Pathways of folding of reduced bovine pancreatic ribonuclease. 
  • Percutaneous cervical oesophageal cannulation in the dog for the performance of prolonged oesophageal pH and manometric studies. 
  • Permeability properties of rat renal lysosomes. 
  • Pharmacological characterization and immunoaffinity purification of metabotropic glutamate receptor from Drosophila overexpressed in Sf9 cells. 
  • Phase-lifetime spectrophotometry of deoxycholate-purified bacteriorhodopsin reconstituted into asolectin vesicles. 
  • Phase-lifetime spectrophotometry of membranes from ion flux mutants of Halobacterium halobium. 
  • Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange. 
  • Photoinduced electron transfer between the Rieske iron-sulfur protein and cytochrome c(1) in the Rhodobacter sphaeroides cytochrome bc(1) complex. Effects of pH, temperature, and driving force. 
  • Physical and chemical properties of rabbit muscle phosphofructokinase cross-linked with dimethyl suberimidate. 
  • Physico-chemical incompatibilities of parenteral admixtures Aramine and Solu-Cortef. 
  • Phytotoxicity of soluble graphitic nanofibers to model plant species. 
  • Pigment formation from L-tryptophan by a particulate fraction from an Achromobacter species. 
  • Polymerization of actin. IV. Role of Ca++ and H+ in the assembly of actin and in membrane fusion in the acrosomal reaction of echinoderm sperm. 
  • Polyvinyl pyrrolidone: a novel cryoprotectant in islet cell cryopreservation. 
  • Possible protein binding displacement interaction between glibenclamide and metolazone. 
  • Prenatal diagnosis of Pompe's disease (type II glycogenosis) in chorionic villus biopsy using maltose as a substrate. 
  • Prevalence, characteristics, and treatment outcomes of reflux hypersensitivity detected on pH-impedance monitoring. 
  • Prevention of recurrent calcium stone formation with potassium citrate therapy in patients with distal renal tubular acidosis. 
  • Probing the folding intermediate of Bacillus subtilis RNase P protein by nuclear magnetic resonance. 
  • Production of superoxide anion by an NADPH-oxidase from rat pulmonary macrophages. 
  • Profound increase in viscosity and aggregation of pig gastric mucin at low pH. 
  • Programmed population control by cell-cell communication and regulated killing. 
  • Properties and regulation of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans. 
  • Protein biosynthesis on chick oviduct polyribosomes. I. Changes during estrogen-mediated tissue differentiation. 
  • Protein purification: adsorption chromatography on controlled pore glass with the use of chaotropic buffers. 
  • Proteinase activity and stability of natural bromelain preparations. 
  • Proton NMR of Escherichia coli sulfite reductase: the unligated hemeprotein subunit. 
  • Protonation state of Glu142 differs in the green- and blue-absorbing variants of proteorhodopsin. 
  • Protonophore- and pH-insensitive glucose and sucrose accumulation detected by FRET nanosensors in Arabidopsis root tips. 
  • Pulmonary histopathology in an experimental model of chronic aspiration is independent of acidity. 
  • Pulmonary vasodilator responses to RP 52891 are mediated by activation of a glibenclamide-sensitive K+ATP channel. 
  • Purification and assembly of FtsZ. 
  • Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli. 
  • Purification and properties of sulfite oxidase from chicken liver. Presence of molybdenum in sulfite oxidase from diverse sources. 
  • Purification and properties of xanthine dehydroganase from Micrococcus lactilyticus. 
  • Pyrazinamide and pyrazinoic acid activity against tubercle bacilli in cultured human macrophages and in the BACTEC system. 
  • Quantitative Mapping of the Spatial Distribution of Nanoparticles in Endo-Lysosomes by Local pH. 
  • Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides. 
  • Quantitative protein stability measurement in vivo. 
  • Quantum dot penetration into viable human skin. 
  • Radium and barium removal through blending hydraulic fracturing fluids with acid mine drainage. 
  • Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. 
  • Rapid in vitro assembly of Caulobacter crescentus FtsZ protein at pH 6.5 and 7.2. 
  • Rapid radiometric method for pyrazinamide susceptibility testing of Mycobacterium tuberculosis. 
  • Rapid self-healing hydrogels. 
  • Re-evaluation of acid-base prediction rules in patients with chronic respiratory acidosis. 
  • Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors. 
  • Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion. 
  • Recent and innovative methods for detection of bacteremia and fungemia. 
  • Recombinant human gamma-interferon induces human monocyte polykaryon formation. 
  • Reductive dehalogenation of trichloroethene vapors in an anaerobic biotrickling filter. 
  • Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design. 
  • Regulation of interleukin-8 expression by cellular pH in human pancreatic adenocarcinoma cells. 
  • Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. 
  • Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893. 
  • Regulation of platelet heparanase during inflammation: role of pH and proteinases. 
  • Regulation of protein phosphorylation and motility of sperm by cyclic adenosine monophosphate and calcium. 
  • Regulation of reconstituted renal Na+/H+ exchanger by calcium-dependent protein kinases. 
  • Regulation of renal Na(+)-H+ exchanger by cAMP-dependent protein kinase. 
  • Regulation of the renal Na+-H+ exchanger. 
  • Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. 
  • Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy. 
  • Relationship between phosphaluria and acute hypercapnia in the rat. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with an adenosine 5'-triphosphate analog. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with aspartate analogs. 
  • Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with carbamyl phosphate. 
  • Relaxation spectra of enzymatic reactions. 
  • Relaxation spectra of ribonuclease. II. Isomerization of ribonuclease at neutral pH values. 
  • Relaxation spectra of ribonuclease. VII. The interaction of ribonuclease with uridine 2',3'-cyclic phosphate. 
  • Removal of 2-MIB and geosmin using UV/persulfate: contributions of hydroxyl and sulfate radicals. 
  • Renal medullary hypoxia during experimental cardiopulmonary bypass: a pilot study. 
  • Reproducibility of 24-hour intraesophageal pH monitoring. 
  • Respiratory physiology of house sparrows in relation to high-altitude flight. 
  • Reversible binding of platelet-derived growth factor-AA, -AB, and -BB isoforms to a similar site on the "slow" and "fast" conformations of alpha 2-macroglobulin. 
  • Ribozyme cleavage of a 2,5-phosphodiester linkage: mechanism and a restricted divalent metal-ion requirement. 
  • Robust IR-based detection of stable and fractionally populated G-C+ and A-T Hoogsteen base pairs in duplex DNA. 
  • Role of conserved tyrosine 343 in intramolecular electron transfer in human sulfite oxidase. 
  • Role of macrophages and dendritic cells in primary cytotoxic T lymphocyte responses. 
  • Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans. 
  • Roles of mucus adhesion and cohesion in cough clearance. 
  • SERS nanosensors and nanoreporters: golden opportunities in biomedical applications. 
  • SERS-based plasmonic nanobiosensing in single living cells. 
  • Safety profile of L-arginine infusion in moderately severe falciparum malaria. 
  • Saliva nicotine as an index of plasma levels in nicotine skin patch users. 
  • Scanning electron microscopy studies in muscular dystrophy. 
  • Selective association of spectrin with the cytoplasmic surface of human erythrocyte plasma membranes. Quantitative determination with purified (32P)spectrin. 
  • Selenium speciation in coal ash spilled at the Tennessee Valley Authority Kingston site. 
  • Self-association and oxygen-binding characteristics of the isolated subunits of Limulus polyphemus hemocyanin. 
  • Sensitive analysis of [D-Pen2,5]enkephalin in rat serum by capillary electrophoresis and laser-induced fluorescence detection. 
  • Separation of promethazine and thioridazine using capillary electrophoresis with end-column amperometric detection. 
  • Sickling times of individual erythrocytes at zero Po2. 
  • Simple model for hormone-activated adenylate cyclase systems. 
  • Simultaneous administration of glucose and hyperoxic gas achieves greater improvement in tumor oxygenation than hyperoxic gas alone. 
  • Simultaneous determination of guanine, uric acid, hypoxanthine and xanthine in human plasma by reversed-phase high-performance liquid chromatography with amperometric detection. 
  • Site-specific incorporation of 3-nitrotyrosine as a probe of pKa perturbation of redox-active tyrosines in ribonucleotide reductase. 
  • Skeletal muscle pH assessed by biochemical and 31P-MRS methods during exercise and recovery in men. 
  • Soluble proteins delivered to dendritic cells via pH-sensitive liposomes induce primary cytotoxic T lymphocyte responses in vitro. 
  • Sorption of 243Am(III) to multiwall carbon nanotubes. 
  • Specific activities of dolastatin 10 and peptide derivatives against Cryptococcus neoformans. 
  • Specificity analysis of antibodies to single-stranded micrococcal DNA in the sera of normal human subjects and patients with systemic lupus erythematosus. 
  • Spectral perturbations and oligomer/monomer formation in 124-kilodalton Avena phytochrome. 
  • Spectroscopic studies of the molybdenum-containing dimethyl sulfoxide reductase from Rhodobacter sphaeroides f. sp. denitrificans. 
  • Spermidine-Induced Attraction of Like-Charged Surfaces Is Correlated with the pH-Dependent Spermidine Charge: Force Spectroscopy Characterization. 
  • Spot hemoglobin. Studies on the Root effect hemoglobin of a marine teleost. 
  • Stability of oxidized Escherichia coli thioredoxin and its dependence on protonation of the aspartic acid residue in the 26 position. 
  • Statistical estimation of statistical mechanical models: helix-coil theory and peptide helicity prediction. 
  • Steady state kinetics of ATP synthesis and hydrolysis catalyzed by reconstituted chloroplast coupling factor. 
  • Steady state kinetics of soluble and membrane-bound mitochondrial ATPase. 
  • Steady-state kinetic study of fatty acid synthase from chicken liver. 
  • Steric factors moderate conformational fluidity and contribute to the high proton sensitivity of Root effect hemoglobins. 
  • Stimulation of the T3-T cell receptor-associated Ca2+ influx enhances the activity of the Na+/H+ exchanger in a leukemic human T cell line. 
  • Strain variation and morphogenesis of yeast- and mycelial-phase Candida albicans in low-sulfate, synthetic medium. 
  • Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans. 
  • Structural analysis of some soluble elastins by means of FT-IR and 2D IR correlation spectroscopy. 
  • Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia. 
  • Structural and functional studies of hemoglobin Suresnes (arg 141 alpha 2 replaced by His beta 2). Consequences of disrupting an oxygen-linked anion-binding site. 
  • Structural and pH dependence of excited state PCET reactions involving reductive quenching of the MLCT excited state of [RuII(bpy)2(bpz)]2+ by hydroquinones. 
  • Structural basis for the remarkable stability of Bacillus subtilis lipase (Lip A) at low pH. 
  • Structural basis for the root effect in haemoglobin. 
  • Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex. 
  • Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors. 
  • Structure and binding of the H4 histone tail and the effects of lysine 16 acetylation. 
  • Structure and oxygen equilibrium of the three coelomic cell hemoglobins of the echiuran worm Thalassema mellita (Conn). 
  • Structure of macromolecular aggregates. I. Aggregation-induced conformational changes in polypeptides. 
  • Structure of the major peanut allergen Ara h 1 may protect IgE-binding epitopes from degradation. 
  • Structure, function, and assembly in the hemocyanin system of the scorpion, Androctonus australis. 
  • Studies of the phosphoenzyme intermediate of the yeast plasma membrane proton-translocating ATPase. 
  • Studies on alpha-actinin-like proteins liberated during trypsin digestion of alpha-actinin and of myofibrils. 
  • Studies on photosystem I. Characteristics of "310 material" isolated from spinach chloroplasts. 
  • Sublethal effects of pentachlorophenol in abalone (Haliotis rufescens) veliger larvae as measured by (31)P-NMR. 
  • Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system. 
  • Suprastructures and dynamic properties of Mycobacterium tuberculosis FtsZ. 
  • Surface characterization of untreated and solvent-extracted rice straw. 
  • Synaptic cleft acidification and modulation of short-term depression by exocytosed protons in retinal bipolar cells. 
  • Synchronous luminescence: a new detection technique for multiple fluorescent probes used for DNA sequencing. 
  • Targeting cell surface F1F0 ATP synthase in cancer therapy. 
  • Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment. 
  • The ATP binding site of the yeast plasma membrane proton-translocating ATPase. 
  • The Aspergillus fumigatus P-type Golgi apparatus Ca2+/Mn2+ ATPase PmrA is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis. 
  • The Mechanism of HdeA Unfolding and Chaperone Activation. 
  • The Presence and Anti-HIV-1 Function of Tenascin C in Breast Milk and Genital Fluids. 
  • The absorption of oleic acid from emulsion and micellar solution. 
  • The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat. 
  • The activity of camptothecin analogues is enhanced in histocultures of human tumors and human tumor xenografts by modulation of extracellular pH. 
  • The anion in salt taste: a possible role for paracellular pathways. 
  • The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. 
  • The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins. 
  • The chloride transporter Na(+)-K(+)-Cl- cotransporter isoform-1 contributes to intracellular chloride increases after in vitro ischemia. 
  • The compact conformation of fibronectin is determined by intramolecular ionic interactions. 
  • The contribution of leukocytes and bacteria to the low pH of empyema fluid. 
  • The dose-related effects of nitric oxide synthase inhibition on cerebral blood flow during isoflurane and pentobarbital anesthesia. 
  • The effect of depressing glial function in rat brain in situ on ion homeostasis, synaptic transmission, and neuron survival. 
  • The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment. 
  • The effect of systemic acidosis on perfusion of replanted extremities. 
  • The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients. 
  • The effects of atrial fibrillation on myocardial blood flow and energetics. 
  • The effects of ethanol on pancreatic blood flow in awake and anesthetized dogs. 
  • The effects of plasma and brain magnesium concentrations on lidocaine-induced seizures in the rat. 
  • The fate of inorganic phosphate and pH in regional myocardial ischemia and infarction: a noninvasive 31P NMR study. 
  • The hemoglobin of the crossopterygian fish, Latimeria chalumnae (Smith). Subunit structure and oxygen equilibria. 
  • The impact of tumor physiology on camptothecin-based drug development. 
  • The influence of xenon, nitrous oxide and nitrogen on gas bubble expansion during cardiopulmonary bypass. 
  • The interaction of aspartate aminotransferase with alpha-methylaspartic acid. 
  • The international standard for atrial natriuretic factor. Calibration by an international collaborative study. 
  • The ionic and metabolic responses associated with neuronal depression of Leão's type in cerebral cortex and in hippocampal formation. 
  • The nature of the axial ligands of spinach cytochrome. 
  • The nicotinamide adenine dinucleotides as allosteric effectors of human hemoglobin. 
  • The novel alkali tolerance function of tfxG in Sinorhizobium meliloti. 
  • The pathogenesis of the low pleural fluid pH in esophageal rupture. 
  • The pleuropulmonary consequences of esophageal rupture: an experimental model. 
  • The relationship between intracellular and extracellular pH in spontaneous canine tumors. 
  • The relationship of Mo, molybdopterin, and the cyanolyzable sulfur in the Mo cofactor. 
  • The role of leukotrienes in the late hemodynamic manifestations of group B streptococcal sepsis in piglets. 
  • The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification. 
  • The role of tyrosine 343 in substrate binding and catalysis by human sulfite oxidase. 
  • The stability of silver nanoparticles in a model of pulmonary surfactant. 
  • The use of high-frequency oscillating ventilation to facilitate stability during neonatal thoracoscopic operations. 
  • The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells. 
  • The vomiting infant. 
  • The water permeability of lens aquaporin-0 depends on its lipid bilayer environment. 
  • Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST. 
  • Thermodynamic effects of reduction of the active-site disulfide of Escherichia coli thioredoxin explored by differential scanning calorimetry. 
  • Time-dependent effects of prolonged hypercapnia on cerebrovascular parameters in dogs: acid-base chemistry. 
  • Toward Hyperpolarized 19 F Molecular Imaging via Reversible Exchange with Parahydrogen. 
  • Transdermal nicotine replacement in pregnancy: maternal pharmacokinetics and fetal effects. 
  • Transport properties of the calcium ionophore ETH-129. 
  • Treatment Response in Patients with Stones, and Low Urinary pH and Hypocitraturia Stratified by Body Mass Index. 
  • Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution. 
  • Tryptic cleavage of rat liver sulfite oxidase. Isolation and characterization of molybdenum and heme domains. 
  • ULTRAVIOLET ROTATORY DISPERSION OF ASPARTIC AMINOTRANSFERASE. 
  • Ultrasonic attenuation measurements in phospholipid dispersions. 
  • Umbilical cord blood gases for term healthy newborns. 
  • Underwater life support based on immobilized oxygen carriers. 
  • Urea tolerance as a molecular adaptation of elasmobranch hemoglobins. 
  • Urinary and biliary excretion of 14C-gossypol in swine. 
  • Urologic sepsis/shock. 
  • Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein. 
  • Vanilloid receptor activation by 2- and 10-microm particles induces responses leading to apoptosis in human airway epithelial cells. 
  • Vascular renin-angiotensin: a possible autocrine or paracrine system in control of vascular function. 
  • Vinculin tail conformation and self-association is independent of pH and H906 protonation. 
  • Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide. 
  • Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes. 
  • WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification. 
  • Will hyperthermia conquer the elusive hypoxic cell? Implications of heat effects on tumor and normal-tissue microcirculation. 
  • Xanthine urolithiasis. 
  • Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge. 
  • pH dependence of [3H]norepinephrine uptake into catecholamine storage vesicles isolated from rat brain, heart and adrenal medulla. 
  • pH dependence of adenosine 5'-triphosphate synthesis and hydrolysis catalyzed by reconstituted chloroplast coupling factor. 
  • pH dependence of kinetics and steady-state block of cardiac sodium channels by lidocaine. 
  • pH effects on measurements of ionized calcium and ionized magnesium in blood. 
  • pH stability of individual folates during critical sample preparation steps in prevision of the analysis of plant folates. 
  • pH-dependent conformational change of gastric mucin leads to sol-gel transition. 
  • pH-dependent conformational changes of ferricytochrome c induced by electrode surface microstructure. 
  • pH-sensitive NMDA inhibitors improve outcome in a murine model of SAH. 
  • pH-stat cooling improves cerebral metabolic recovery after circulatory arrest in a piglet model of aortopulmonary collaterals. 
  • pKa does not predict pH potentiation of sodium channel blockade by lidocaine and W6211 in guinea pig ventricular myocardium. 
  • trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1. 
  • vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly. 
  • α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide. 
• 

  Keywords of People

  • Bennett, Vann, George B. Geller Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • Charles, Hal Cecil, Associate Professor of Radiology, Radiology
  • Cohen, Seth Morris, Associate Professor of Surgery, Surgery, Head and Neck Surgery and Communication Sciences
  • Craciunescu, Oana, Associate Professor of Radiation Oncology, Radiation Oncology
  • Dwyer, Gary, Research Scientist, Senior, Earth and Ocean Sciences
  • Erickson, Harold Paul, James B. Duke Professor of Cell Biology, Biomedical Engineering
  • Hsu-Kim, Heileen, Mary Milus Yoh and Harold L. Yoh, Jr. Associate Professor of Civil and Environmental Engineering, Civil and Environmental Engineering
  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology, Neuroanesthesia
  • Katz, David F., Nello L. Teer, Jr. Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering, Biomedical Engineering
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship
  • Liton, Paloma Borrajo, Associate Professor in Ophthalmology, Pathology
  • MacFall, James R., Adjunct Professor in the Department of Radiology, Radiology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Moon, Richard Edward, Professor of Anesthesiology, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • Nielsen, Karen Cristina, Associate Professor of Anesthesiology, Anesthesiology, Ambulatory
  • Oas, Terrence Gilbert, Professor of Biochemistry, Duke Cancer Institute
  • Preminger, Glenn Michael, James F. Glenn, M.D. Professor of Urology, Surgery
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology
  • Yancy Jr., William Samuel, Associate Professor of Medicine, Medicine, General Internal Medicine