Hydroxymethylglutaryl CoA Reductases
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Subject Areas on Research
- Adaptive immune response to therapy in hmgcr autoantibody myopathy.
- Altered carbohydrate, lipid, and xenobiotic metabolism by liver from rats flown on Cosmos 1887.
- Cholesterol homeostasis in the rat with a portacaval anastomosis.
- Cholesterol homeotasis in rats fed a purified diet.
- Clinical application of cardiovascular pharmacogenetics.
- Effect of type of diet and feeding status on modulation of hepatic HMG-CoA reductase in rats.
- Effects of dietary pectin and cellulose on hepatic and intestinal mixed-function oxidations and hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the rat.
- Fluorescent low density lipoprotein for observation of dynamics of individual receptor complexes on cultured human fibroblasts.
- Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells.
- Open-label, ascending dose, prospective cohort study evaluating the antiviral efficacy of Rosuvastatin therapy in serum and lipid fractions in patients with chronic hepatitis C.
- Pharmacometabolomics Meets Genetics: A "Natural" Clinical Trial of Statin Effects.
- Short-term changes in hepatic HMG-CoA reductase in rats fed diets containing cholesterol or oat bran.
- The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides.
- Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants.
- Using pharmacogenetics to improve drug safety and efficacy.