Hyperlipidemias

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  Subject Areas on Research

  • 2015 ACC/AHA Focused Update of Secondary Prevention Lipid Performance Measures: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures. 
  • A Cost Analysis of Universal versus Targeted Cholesterol Screening in Pediatrics. 
  • A comparison of the effectiveness of lipid-lowering therapy between HIV- and non-HIV-infected subjects with hyperlipidaemia. 
  • A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia: a randomized, controlled trial. 
  • A new extended-release niacin (Niaspan): efficacy, tolerability, and safety in hypercholesterolemic patients. 
  • A review of decision aids to assess cardiovascular risk. 
  • Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. 
  • Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice. 
  • Adverse effects of corticosteroids on the cardiovascular system. 
  • African American-Caucasian American differences in aortic valve replacement in patients with severe aortic stenosis. 
  • Analytical performance and clinical utility of a direct LDL-cholesterol assay in a hyperlipidemic pediatric population. 
  • Assessing the accuracy of a point-of-care analyzer for hyperlipidaemia in western Kenya. 
  • Association between statin use and uveitis: results from the Pacific Ocular Inflammation study. 
  • Association of serum triiodothyronine with B-type natriuretic peptide and severe left ventricular diastolic dysfunction in heart failure with preserved ejection fraction. 
  • Atherosclerotic disease in non-insulin-dependent diabetes mellitus: role of abnormal lipids and the place for lipid-altering therapies. 
  • Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E. 
  • Can group medical clinics improve lipid management in diabetes? 
  • Cannabis Use and Electrocardiographic Myocardial Injury. 
  • Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species. 
  • Carbohydrate restriction is effective in improving atherogenic dyslipidemia even in the absence of weight loss. 
  • Cardiometabolic comorbidities and epithelial ovarian cancer risk among African-American women in the African-American Cancer Epidemiology Study (AACES). 
  • Cardiovascular risk factors in young adult survivors of childhood acute lymphoblastic leukemia. 
  • Cases from the Osler Medical Service at Johns Hopkins University. Zieve syndrome. 
  • Central corneal thickness and its associations with ocular and systemic factors: the Singapore Malay Eye Study. 
  • Co-occurring reasons for medication nonadherence within subgroups of patients with hyperlipidemia. 
  • Combination drug therapy for combined hyperlipidemia. 
  • Complications of human immunodeficiency virus therapy. 
  • Continuity of medication management in Medicaid patients with chronic comorbid conditions: An examination by mental health status. 
  • Coronary Plaque Characterization in Psoriasis Reveals High-Risk Features That Improve After Treatment in a Prospective Observational Study. 
  • Countering clinical inertia in lipid management: Expert workshop summary. 
  • Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood. 
  • Diabetes medication regimens and patient clinical characteristics in the national patient-centered clinical research network, PCORnet. 
  • Diet-induced obese mice retain endogenous leptin action. 
  • Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. 
  • Dual hepatic metabolism of cerivastatin--clarifications. 
  • Dyslipidaemia and microvascular disease in the retina. 
  • Dyslipoproteinemia and premature atherosclerosis in pediatric systemic lupus erythematosus. 
  • Effect of Massachusetts health reform on chronic disease outcomes. 
  • Effect of extended-release niacin on new-onset diabetes among hyperlipidemic patients treated with ezetimibe/simvastatin in a randomized controlled trial. 
  • Effect of heparin on vitamin A induced hyperlipidemia in rats. 
  • Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: an observational study. 
  • Effect of switching to a high-deductible health plan on use of chronic medications. 
  • Effectiveness and tolerability of adding ezetimibe to niacin-based regimens for treatment of primary hyperlipidemia. 
  • Effectiveness of an App and Provider Counseling for Obesity Treatment in Primary Care. 
  • Effects of exercise and weight loss on cardiac risk factors associated with syndrome X. 
  • Effects of exercise on plasma lipoproteins. 
  • Effects of nurse-managed protocols in the outpatient management of adults with chronic conditions: a systematic review and meta-analysis. 
  • Effects of the amount and intensity of exercise on plasma lipoproteins. 
  • Estimating the likelihood of significant coronary artery disease. 
  • Evaluation and clinical application of a direct low-density lipoprotein cholesterol assay in normolipidemic and hyperlipidemic adults. 
  • Evidence supporting secondary prevention strategies. 
  • Extended-release niacin for modifying the lipoprotein profile. 
  • Gender and racial differences in lipoprotein subclass distributions: the STRRIDE study. 
  • General medical burden in bipolar disorder: findings from the LiTMUS comparative effectiveness trial. 
  • Genetically determined height and coronary artery disease. 
  • Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis. 
  • Guideline-directed therapies for comorbidities and clinical outcomes among individuals with atrial fibrillation. 
  • Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. 
  • Health burden associated with visual impairment in Singapore: the Singapore epidemiology of eye disease study. 
  • Heart disease epidemic in Pakistan: women and men at equal risk. 
  • Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance. 
  • High-sensitivity C-reactive protein elevation in patients with prior myocardial infarction in the United States. 
  • Homocysteine testing in patients with acute ischemic stroke. 
  • Hostility during late adolescence predicts coronary risk factors at mid-life. 
  • Hyperlipidaemia in HIV-infected patients on lopinavir/ritonavir monotherapy in resource-limited settings. 
  • Hyperlipidemia and transplantation: etiologic factors and therapy. 
  • Hyperlipidemia in children and adolescents. 
  • Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease. 
  • Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP. 
  • Impact of Gender on Satisfaction and Confidence in Cholesterol Control Among Veterans at Risk for Cardiovascular Disease. 
  • Impact of Pulmonary Hypertension on Survival Following Device Closure of Atrial Septal Defects. 
  • Increasing copayments and adherence to diabetes, hypertension, and hyperlipidemic medications. 
  • Influence of clinical trial enrollment on the quality of care and outcomes for patients with non-ST-segment elevation acute coronary syndromes. 
  • Influence of ethnicity on the efficacy and utilization of bariatric surgery in the USA. 
  • Interference from lipemia in cell count by hematology analyzers. 
  • Interventions to Improve Statin Tolerance and Adherence in Patients at Risk for Cardiovascular Disease : A Systematic Review for the 2020 U.S. Department of Veterans Affairs and U.S. Department of Defense Guidelines for Management of Dyslipidemia. 
  • Ischemic cranial nerve 6 palsy and lipemia retinalis in a patient with hypertriglyceridemia. 
  • Juvenile idiopathic arthritis and future risk for cardiovascular disease: a multicenter study. 
  • Lack of effect of lovastatin on restenosis after coronary angioplasty. Lovastatin Restenosis Trial Study Group. 
  • Lipid management in patients with unstable angina pectoris and non-ST-segment elevation acute myocardial infarction (from CRUSADE). 
  • Lipid testing in patients with rheumatoid arthritis and key cardiovascular-related comorbidities: a medicare analysis. 
  • Lipids and diabetic retinopathy. 
  • Lipids, statins, and clinical outcomes in heart failure: rethinking the data. 
  • Lipoprotein(a) Testing Patterns in a Large Health System. 
  • Long-term cardiovascular outcomes in patients with atrial fibrillation and atherothrombosis in the REACH Registry. 
  • Long-term efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in hyperlipidaemic patients with diabetes or metabolic syndrome. 
  • Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia. 
  • Long-term safety and efficacy of triple combination ezetimibe/simvastatin plus extended-release niacin in patients with hyperlipidemia. 
  • Management of Dyslipidemia for Cardiovascular Disease Risk Reduction: Synopsis of the 2020 Updated U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline. 
  • Management of hyperlipidemia in older adults. 
  • Medication discontinuation after curative surgery for sporadic primary hyperparathyroidism. 
  • Menorrhagia in patients with type I glycogen storage disease. 
  • Metabolic effects associated with atypical antipsychotic treatment in the developmentally disabled. 
  • Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia. 
  • Metabolic syndrome: definition, pathophysiology, and mechanisms. 
  • Modeling statin myopathy in a human skeletal muscle microphysiological system. 
  • Molecular approaches for the treatment of atherosclerosis. 
  • Multiple-dose efficacy and safety of an extended-release form of niacin in the management of hyperlipidemia. 
  • Obesity in American-Indian children: prevalence, consequences, and prevention. 
  • Patient-reported medication adherence barriers among patients with cardiovascular risk factors. 
  • Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. 
  • PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies. 
  • Prevalence of conventional risk factors in patients with coronary heart disease. 
  • Prevalence of obesity and cardiovascular risk factors among manufacturing company employees in Kentucky. 
  • Primary Prevention of Heart Failure in Women. 
  • Rationale and design of a nurse-led intervention to extend the HIV treatment cascade for cardiovascular disease prevention trial (EXTRA-CVD). 
  • Relation between previous lipid-lowering therapy and infarct size (creatine kinase-MB level) in patients presenting with acute myocardial infarction. 
  • Relation of Cannabis Use to Elevated Atherosclerotic Cardiovascular Disease Risk Score. 
  • Relations between deletion polymorphism of the angiotensin-converting enzyme gene and insulin resistance, glucose intolerance, hyperinsulinemia, and dyslipidemia. 
  • Relationship between antecedent angina pectoris and short-term prognosis after thrombolytic therapy for acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group. 
  • Response to Letter Regarding Article, "Hyperlipidemia in Early Adulthood Increases Long-Term Risk of Coronary Heart Disease". 
  • Results from a practice-based lipid clinic model in achieving low density lipoprotein cholesterol goals. 
  • Retinal arteriolar emboli and long-term mortality: pooled data analysis from two older populations. 
  • Retinal vein occlusion: an approach to diagnosis, systemic risk factors and management. 
  • Review: in adult outpatients, nurse-managed protocols improve hemoglobin A1c levels and blood pressure. 
  • Risk factors for stroke on left ventricular assist devices. 
  • Screening for metabolic and reproductive complications in obese children and adolescents. 
  • Sex and age differences in lipid response to chronic infection with the hepatitis C virus in the United States National Health and Nutrition Examination Surveys. 
  • Sex-Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors. 
  • Specialty Pharmaceuticals for Hyperlipidemia--Impact on Insurance Premiums. 
  • Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network. 
  • Statin therapy--time to turn the focus from efficacy to implementation? 
  • Stroke in patients with acute coronary syndromes: incidence and outcomes in the platelet glycoprotein IIb/IIIa in unstable angina. Receptor suppression using integrilin therapy (PURSUIT) trial. The PURSUIT Investigators. 
  • Submucosal resection of giant gastric lipoma. 
  • Syndrome X and diabetes: what is the mystery? 
  • Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. 
  • Targeting cardiovascular risk associated with both low density and high density lipoproteins using statin-niacin combination therapy. 
  • The Cardiovascular Intervention Improvement Telemedicine Study (CITIES): rationale for a tailored behavioral and educational pharmacist-administered intervention for achieving cardiovascular disease risk reduction. 
  • The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer. 
  • The importance of family history in cerebrovascular disease. 
  • The relation between methods and recommendations in clinical practice guidelines for hypertension and hyperlipidemia. 
  • The retina in type 5 hyperlipoproteinemia. 
  • The significance of coronary calcification detected by fluoroscopy. A report of 360 patients. 
  • Therapy Insight: cardiovascular disease in pediatric systemic lupus erythematosus. 
  • Thrombogenicity markers for early diagnosis and prognosis in COVID-19: a change from the current paradigm? 
  • Track: A randomized controlled trial of a digital health obesity treatment intervention for medically vulnerable primary care patients. 
  • Treatment of hyperlipidemia by specialists versus generalists as secondary prevention of coronary artery disease. 
  • Treatment of hyperlipidemia with combined niacin-statin regimens. 
  • Triglycerides: Emerging Targets in Diabetes Care? Review of Moderate Hypertriglyceridemia in Diabetes. 
  • Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack. 
  • Use of combination antihypertensive therapy initiation in older Americans without prevalent cardiovascular disease. 
  • Using "old" medications to fight new COVID-19: Re-purposing with a purpose. 
  • Using BMI to determine cardiovascular risk in childhood: how do the BMI cutoffs fare? 
  • Vascular factors and risk for neuropsychiatric symptoms in Alzheimer's disease: the Cache County Study. 
  • Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. 
  • Weight-loss talks: what works (and what doesn't). 
  • Which is the true channel? 
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  Keywords of People

  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Olsen, Maren Karine, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Yancy Jr., William Samuel, Professor of Medicine, Medicine, General Internal Medicine