Hypersensitivity

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  Subject Areas on Research

  • A comparison of adverse reaction rates for PAS C versus plasma platelet units. 
  • A pooled multisite analysis of the effects of atopic medical conditions in glioma risk in different ethnic groups. 
  • A retrospective study of complications of therapeutic plasma exchange in myasthenia. 
  • A systematic review and meta-analysis of neuromodulators to treat chronic airway hypersensitivity. 
  • Abnormalities of chemotactic lymphokine synthesis and mononuclear leukocyte chemotaxis in Wiskott-Aldrich syndrome. 
  • Advances in asthma/allergy. 
  • Allergen-induced airway disease is mouse strain dependent. 
  • Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse. 
  • Allergic lung responses are increased in prostaglandin H synthase-deficient mice. 
  • Allergic reactions to E. coli L-asparaginase do not affect outcome in childhood B-precursor acute lymphoblastic leukemia: a Children's Oncology Group Study. 
  • Allergies, obesity, other risk factors and survival from pancreatic cancer. 
  • An extension of the sign test for replicated measurements. 
  • Antibody desensitization therapy in highly sensitized lung transplant candidates. 
  • Approaching a Scientific Consensus on the Association between Allergies and Glioma Risk: A Report from the Glioma International Case-Control Study. 
  • Are allergens more abundant and/or more stable than other proteins in pollens and dust? 
  • Aseptic lymphocyte-dominated vasculitis-associated lesion: a clinicopathologic review of an underrecognized cause of prosthetic failure. 
  • Assessment of autoantibodies to meningioma in a population-based study. 
  • Assessment of type of allergy and antihistamine use in the development of glioma. 
  • Association between glioma and history of allergies, asthma, and eczema: a case-control study with three groups of controls. 
  • Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking. 
  • Brucellosis. Indications for splenectomy. 
  • Characterization of a novel high-dose ovalbumin-induced murine model of allergic sinonasal inflammation. 
  • Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception. 
  • Corneal Scheimpflug topography values to distinguish between normal eyes, ocular allergy, and keratoconus in children. 
  • Data quality from a longitudinal study of adolescent health at schools near industrial livestock facilities. 
  • Disease-Specific Expression of Conjunctiva Associated Lymphoid Tissue (CALT) in Mouse Models of Dry Eye Disease and Ocular Allergy. 
  • EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity. 
  • Early childcare enrollment and childhood wheezing phenotypes. 
  • Early-Life Intranasal Colonization with Nontypeable Haemophilus influenzae Exacerbates Juvenile Airway Disease in Mice. 
  • Early-life antibiotic exposure increases the risk of developing allergic symptoms later in life: A meta-analysis. 
  • Effect of beta-adrenergic blockade and sympathetic stimulation on canine bronchial mast cell response to immune degranulation in vivo. 
  • Effect of different coffees on esophageal acid contact time and symptoms in coffee-sensitive subjects. 
  • Emerging therapeutics for ocular surface disease. 
  • Escape from tolerance in the human X-linked autoimmunity-allergic disregulation syndrome and the Scurfy mouse. 
  • Exogenous leptin enhances markers of airway fibrosis in a mouse model of chronic allergic airways disease. 
  • Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE. 
  • HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. 
  • Home environmental and lifestyle factors associated with asthma, rhinitis and wheeze in children in Beijing, China. 
  • IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses. 
  • IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era. 
  • In-Flight Injuries Involving Children on Commercial Airline Flights. 
  • Incidence of allergic reactions with fresh frozen plasma or cryo-supernatant plasma in the treatment of thrombotic thrombocytopenic purpura. 
  • Induction and Characterization of the Allergic Eye Disease Mouse Model. 
  • International consensus statement on allergy and rhinology: Olfaction. 
  • Iron supplementation decreases severity of allergic inflammation in murine lung. 
  • L-selectin and intercellular adhesion molecule 1 mediate lymphocyte migration to the inflamed airway/lung during an allergic inflammatory response in an animal model of asthma. 
  • Laboratory animal allergy: an update. 
  • Linking immune responses with fibrosis in allergic eye disease. 
  • Livedo reticularis: a form of allergic vasculitis. Report of 3 cases. 
  • Maternal PUFA status and offspring allergic diseases up to the age of 18 months. 
  • Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases. 
  • Meibomian gland dysfunction is suppressed via selective inhibition of immune responses by topical LFA-1/ICAM antagonism with lifitegrast in the allergic eye disease (AED) model. 
  • Metal Hypersensitivity and Total Knee Arthroplasty. 
  • Metal hypersensitivity: can it mimic infection? 
  • Methacholine-induced cutaneous flare response: bivariate analysis of responsiveness and sensitivity. 
  • Methods to Investigate the Roles for β-Arrestin-2 in Allergic Inflammatory Airway Disease. 
  • New perspectives on the origins and heterogeneity of mast cells. 
  • New reagents on the horizon for immune tolerance. 
  • New roles for mast cells in modulating allergic reactions and immunity against pathogens. 
  • New roles for mast cells in pathogen defense and allergic disease. 
  • Nutrition: an integral component in the health care of children. The interdisciplinary team in action. 
  • Nutritional and antigenic effects of two bovine milk preparations in infants. 
  • Occupational health issues of oral health care workers in Edo State, Nigeria. 
  • Ocular allergy modulation to hi-dose antigen sensitization is a Treg-dependent process. 
  • Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses. 
  • Opportunities to enhance the AAAAI Physician Burnout Survey. 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions. 
  • Payer database and geospatial analysis to evaluate practice patterns in treating allergy in North Carolina. 
  • Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch. 
  • Phenotypes of Recurrent Wheezing in Preschool Children: Identification by Latent Class Analysis and Utility in Prediction of Future Exacerbation. 
  • Physiologic response to chronic house dust mite exposure in mice is dependent on lot characteristics. 
  • Presidential address. Reflections on the 1970s and a look to the future. 
  • Prevention of laboratory animal allergy. 
  • Primary and secondary allergies to laboratory animals. 
  • Prospective study of breast-feeding in relation to wheeze, atopy, and bronchial hyperresponsiveness in the Avon Longitudinal Study of Parents and Children (ALSPAC). 
  • Pseudotumor with superimposed periprosthetic infection following metal-on-metal total hip arthroplasty: a case report. 
  • Recombinant human IL-4 induces IgE and IgG synthesis by normal and atopic donor mononuclear cells. Similar dose response, time course, requirement for T cells, and effect of pokeweed mitogen. 
  • Reconstitution of the human biome as the most reasonable solution for epidemics of allergic and autoimmune diseases. 
  • Reduced allergy and immunoglobulin E among adults with intracranial meningioma compared to controls. 
  • Regulatory B cells that produce IL-10: a breath of fresh air in allergic airway disease. 
  • Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model. 
  • Risk factors for development of systemic lupus erythematosus: allergies, infections, and family history. 
  • Risk factors for increased airway responsiveness to methacholine challenge among laboratory animal workers. 
  • Risk-stratified management to remove low-risk penicillin allergy labels in the patients with COVID-19 in the intensive care unit. 
  • Role of immune stimulation in the etiology of multiple myeloma: a case control study. 
  • Scavenger Receptor BI Attenuates IL-17A-Dependent Neutrophilic Inflammation in Asthma. 
  • Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease. 
  • Serum IgD concentrations in normal infants, children, and adults and in patients with elevated IgE. 
  • Serum immunoglobulins. 3. Abnormalities associated with chronic urticaria in children. 
  • Serum immunoglobulins. I. Levels in normal children and in uncomplicated childhood allergy. 
  • Serum immunoglobulins. II. Levels in children subject to recurrent infection. 
  • Survey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women. 
  • Systemic hypersensitivity reaction to endovascular stainless steel stent. 
  • T helper subsets in allergic eye disease. 
  • TLR4 signaling attenuates ongoing allergic inflammation. 
  • Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study. 
  • The clinical and environmental determinants of airway transcriptional profiles in allergic asthma. 
  • The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace. 
  • The impact of infectious and allergic diseases on the quality of life. 
  • The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. 
  • The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development. 
  • The toxicology of climate change: environmental contaminants in a warming world. 
  • Tissue lesions in hypersensitivity. 
  • Traffic-related air pollution induces non-allergic eosinophilic airway inflammation and cough hypersensitivity in guinea-pigs. 
  • United Airway Disease Among Crop Farmers. 
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  Keywords of People

  • Bradford, William Dalton, Professor of Pathology, Pathology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor Emeritus of Pediatrics, in the School of Medicine, Pediatrics, Allergy and Immunology
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology