Hypersensitivity, Delayed

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  Subject Areas on Research

  • A human mononuclear leukocyte chemotactic factor: characterization, specificity and kinetics of production by homologous leukocytes. 
  • A phase II study of two HIV type 1 envelope vaccines, comparing their immunogenicity in populations at risk for acquiring HIV type 1 infection. AIDS Vaccine Evaluation Group. 
  • Active specific immunotherapy of Dukes B2 and C colorectal carcinoma: comparison of two doses of the vaccine. 
  • Adoptive transfer and specific active immunization of patients with malignant melanoma. 
  • Anti-glycoprotein D monoclonal antibody protects against herpes simplex virus type 1-induced diseases in mice functionally depleted of selected T-cell subsets or asialo GM1+ cells. 
  • Anti-receptor antibody-induced H-Y-specific delayed-type hypersensitivity responses in nonresponder mice. 
  • Anti-receptor antibody-induced suppression of murine H-Y-specific delayed-type hypersensitivity responses. 
  • Blunted stress responses in delayed type hypersensitivity in mice lacking the neuronal isoform of nitric oxide synthase. 
  • Bone marrow and thymus transplantation in ataxia-telangiectasia. 
  • Cardiac arrest/cardiopulmonary resuscitation augments cell-mediated immune function and transiently suppresses humoral immune function. 
  • Characterization of chemotactic activity produced in vivo by a cell-mediated immune reaction in the guinea pig. 
  • Clinical and immunologic features of selective IgA deficiency. 
  • Daily micronutrient supplements enhance delayed-hypersensitivity skin test responses in older people. 
  • Defective cellular immunity associated with chronic mucocutaneous moniliasis and recurrent staphylococcal botryomycosis: immunological reconstitution by allogeneic bone marrow. 
  • Defective mononuclear leukocyte chemotaxis: a previously unrecognized immune dysfunction. Studies in a patient with chronic mucocutaneous candidiasis. 
  • Delayed-type hypersensitivity reaction with iscador M given in combination with cytotoxic chemotherapy. 
  • Delayed-type hypersensitivity skin tests are an independent predictor of human immunodeficiency virus disease progression. Department of Veterans Affairs Cooperative Study Group. 
  • Delayed-type hypersensitivity testing in Tanzanian adults with HIV infection. 
  • Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance. 
  • Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring. 
  • Effective antibody therapy in herpes simplex virus ocular infection. Characterization of recipient immune response. 
  • Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation. 
  • Effector mechanisms in transplant rejection. 
  • Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: immunosuppression, immunogenicity, and relation to immunosuppressive tumor products. 
  • Effects of neoplasms on inflammation: depression of macrophage accumulation after tumor implantation. 
  • Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis. 
  • Enhanced macrophage tumoricidal activity and tumor suppression or regression caused by heat-killed Candida albicans. 
  • Flow cytometric detection of lymphocyte proliferation in eyes with immunogenic inflammation. 
  • Galactose-α-1,3-galactose and delayed anaphylaxis, angioedema, and urticaria in children. 
  • Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma. 
  • HSV-1 retinitis and delayed hypersensitivity in DBA/2 and C57BL/6 mice. 
  • Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VI. Evidence for different T cell receptors in cells that mediate H-21-restricted and H-2D-restricted cutaneous sensitivity responses. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VIII. Suppressor cell pathways in cutaneous sensitivity responses. 
  • Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance. 
  • Human mononuclear leukocyte chemotaxis: a quantitative assay for humoral and cellular chemotactic factors. 
  • IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response. 
  • Immune privilege and suppression of immunogenic inflammation in the anterior chamber of the eye. 
  • Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients. 
  • Immunological mechanisms of allograft rejection. 
  • Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor. 
  • Induction of immune responses by schistosome granuloma macrophages. 
  • Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis. 
  • Intranasal immunization is superior to vaginal, gastric, or rectal immunization for the induction of systemic and mucosal anti-HIV antibody responses. 
  • Introduction: Regulatory B Cell Special Issue-making all the pieces fit. 
  • Localization of functionally different guinea-pig spleen cells in albumin gradients. 
  • Long term disease-free survival and T cell and antibody responses in women with high-risk Her2+ breast cancer following vaccination against Her2. 
  • Lymphopenic immunologic deficiency in identical twins: lymphocyte allografting and graft-versus-host disease following treatment with albumin-gradient-separated paternal bone marrow cells. 
  • Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases. 
  • Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. 
  • Mice deficient in inducible nitric oxide synthase are susceptible to experimental autoimmune uveoretinitis. 
  • Monitoring cellular immune responses to cancer immunotherapy. 
  • Mucosal immunity to HIV-1: systemic and vaginal antibody responses after intranasal immunization with the HIV-1 C4/V3 peptide T1SP10 MN(A). 
  • Non-specific and specific immunotherapy in patients with melanoma. 
  • Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. 
  • Oral feeding with pig peripheral lymphocytes decreases the xenogeneic delayed type hypersensitivity reaction in galactosyltransferase knockout mice. 
  • Phenotypic characterization of skin-infiltrating T cells in cutaneous T-cell lymphoma: comparison with benign cutaneous T-cell infiltrates. 
  • Photoperiod controls the induction, retention, and retrieval of antigen-specific immunological memory. 
  • Photoperiod influences the effects of exercise and food restriction on an antigen-specific immune response in Siberian hamsters. 
  • Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer. 
  • Proceedings: Immunologic similarities between fetal cell antigens and tumor cell antigens in guinea pigs. 
  • Pyoderma gangrenosum, altered delayed hypersensitivity and polyarthritis. 
  • QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immunization in humans. 
  • Quantitating therapeutically relevant T-cell responses to cancer vaccines. 
  • Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. 
  • Role of macrophages in restricting herpes simplex virus type 1 growth after ocular infection. 
  • Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol. 
  • Serum immunoglobulins. 3. Abnormalities associated with chronic urticaria in children. 
  • Severe aplastic anemia associated with chronic mucocutaneous candidiasis. Immunologic and hematologic reconstitution after allogeneic bone marrow transplantation. 
  • Sex differences in photoperiodic and stress-induced enhancement of immune function in Siberian hamsters. 
  • Shifting Paradigms in Allergic Contact Dermatitis: The Role of Innate Immunity. 
  • Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune function. 
  • Short day lengths enhance skin immune responses in gonadectomised Siberian hamsters. 
  • Stressor-specific alterations in corticosterone and immune responses in mice. 
  • Successful tumour immunotherapy: possible role of antibodies to anti-inflammatory factors produced by neoplasms. 
  • The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. 
  • The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer. 
  • The functions and measurement of human B- and T-lymphocytes. 
  • The immunogenetics of the major histocompatibility chromosomal region in man. 
  • The immunologic constant of rejection. 
  • The prognostic significance of recall antigen testing in melanoma patients. 
  • Treatment of marrow graft recipients with thymopentin. 
  • Vaccination with the immediate-early protein ICP47 of herpes simplex virus-type 1 (HSV-1) induces virus-specific lymphoproliferation, but fails to protect against lethal challenge. 
  • Zinc and immunocompetence in elderly people: effects of zinc supplementation for 3 months. 
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  Keywords of People

  • Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology