Hyperthermia, Induced

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  Subject Areas on Research

  • 1H MRI phase thermometry in vivo in canine brain, muscle, and tumor tissue. 
  • 31P magnetic resonance spectroscopy after combined hyperthermia and radiation. 
  • 31P magnetic resonance spectroscopy of animal uveal melanoma. 
  • 3D numerical reconstruction of the hyperthermia induced temperature distribution in human sarcomas using DE-MRI measured tissue perfusion: validation against non-invasive MR temperature measurements. 
  • A Multicenter Randomized Trial to Evaluate Hematologic Toxicities after Hyperthermic Intraperitoneal Chemotherapy with Oxaliplatin or Mitomycin in Patients with Appendiceal Tumors. 
  • A Plasmonic Gold Nanostar Theranostic Probe for In Vivo Tumor Imaging and Photothermal Therapy. 
  • A coaxial microwave applicator for transurethral hyperthermia of the prostate. 
  • A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C. 
  • A comparison of temperatures in canine solid tumours during local and whole-body hyperthermia administered alone and simultaneously. 
  • A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure. 
  • A method of MRI-based thermal modelling for a RF phased array. 
  • A method to convert MRI images of temperature change into images of absolute temperature in solid tumours. 
  • A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US. 
  • A new era for cancer treatment: gold-nanoparticle-mediated thermal therapies. 
  • A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model. 
  • A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas. 
  • A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer. 
  • A phase II trial testing the thermal dose parameter CEM43 degrees T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapy. 
  • A pilot Phase II trial of concurrent radiotherapy, chemotherapy, and hyperthermia for locally advanced cervical carcinoma. 
  • A pilot clinical trial of intravesical mitomycin-C and external deep pelvic hyperthermia for non-muscle-invasive bladder cancer. 
  • A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer. 
  • A role for the copper transporter Ctr1 in the synergistic interaction between hyperthermia and cisplatin treatment. 
  • A systematic review of regional hyperthermia therapy in bladder cancer. 
  • A theoretical model for input impedance of interstitial microwave antennas with choke. 
  • A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral doxil extravasation. 
  • Absence of whole body hyperthermia effect on cisplatin distribution in spontaneous canine tumors. 
  • Accuracy of real time noninvasive temperature measurements using magnetic resonance thermal imaging in patients treated for high grade extremity soft tissue sarcomas. 
  • Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia. 
  • Acute pancreatitis associated with administration of a nitric oxide synthase inhibitor in tumor-bearing dogs. 
  • An improved bolus configuration for commercial multielement ultrasound and microwave hyperthermia systems. 
  • An isolated limb infusion technique: a guide for the perfusionist. 
  • Analysis of prognostic variables which influence early and long-term response of pet animal tumors to radiation alone and radiation plus heat. 
  • Animal modeling and thermal dose. 
  • Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct. 
  • Appendiceal goblet cell carcinomatosis treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. 
  • Application of new technology in clinical hyperthermia. 
  • Automated temperature scanning for hyperthermia treatment monitoring. 
  • Automatic temperature controller for multielement array hyperthermia systems. 
  • Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia. 
  • Benign prostatic hyperplasia. New concepts in the 1990s. 
  • Biological and clinical aspects of hyperthermia in cancer therapy. 
  • Bladder cancer: chemohyperthermia for bladder cancer--clinically effective? 
  • CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels? 
  • Can we settle with single-band radiometric temperature monitoring during hyperthermia treatment of chestwall recurrence of breast cancer using a dual-mode transceiving applicator? 
  • Carcinogenic effects of hyperthermia. 
  • Cardiovascular and metabolic response of tumour-bearing dogs to whole body hyperthermia. 
  • Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas. 
  • Characteristics of microstrip muscle-loaded single-arm Archimedean spiral antennas as investigated by FDTD numerical computations. 
  • Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy. 
  • Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature. 
  • Characterization of tumour temperature distributions in hyperthermia based on assumed mathematical forms. 
  • Chemodosimetry of in vivo tumor liposomal drug concentration using MRI. 
  • Clinical application of thermal isoeffect dose. 
  • Clinical experience with a multi-element ultrasonic hyperthermia system: analysis of treatment temperatures. 
  • Clinical management of silicone intraocular lens condensation. 
  • Clinical outcome after neoadjuvant thermoradiotherapy in high grade soft tissue sarcomas. 
  • Cognitive dysfunction after cardiac surgery: revisiting etiology. 
  • Combination of transurethral and interstitial ultrasound applicators for high-temperature prostate thermal therapy. 
  • Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate. 
  • Combining radiation therapy with other treatment modalities. 
  • Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours. 
  • Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics. 
  • Computational techniques for fast hyperthermia temperature optimization. 
  • Conditional Survival After Cytoreductive Surgery with Heated Intraperitoneal Chemotherapy for Low- and High-Grade Appendiceal Primaries. 
  • Conformal microwave array (CMA) applicators for hyperthermia of diffuse chest wall recurrence. 
  • Consensus guidelines from The American Society of Peritoneal Surface Malignancies on standardizing the delivery of hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal cancer patients in the United States. 
  • Correction of breathing-induced errors in magnetic resonance thermometry of hyperthermia using multiecho field fitting techniques. 
  • Cost-effectiveness of hyperthermic intraperitoneal chemotherapy (HIPEC) at interval debulking of epithelial ovarian cancer following neoadjuvant chemotherapy. 
  • Cumulative minutes with T90 greater than Tempindex is predictive of response of superficial malignancies to hyperthermia and radiation. 
  • Current clinical and research approaches to optimizing regional chemotherapy: novel strategies generated through a better understanding of drug pharmacokinetics, drug resistance, and the development of clinically relevant animal models. 
  • Current status and future directions in appendiceal cancer with peritoneal dissemination. 
  • Current trends in regional therapy for melanoma: lessons learned from 225 regional chemotherapy treatments between 1995 and 2010 at a single institution. 
  • Cytokine and immuno-gene therapy for solid tumors. 
  • Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal cancer. 
  • Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis: outcomes from a single tertiary institution. 
  • Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Society of Surgical Oncology. 
  • Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for gallbladder cancer: a retrospective review. 
  • Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis from rectal cancer. 
  • Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal sarcomatosis. 
  • Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in sarcomatosis from gastrointestinal stromal tumor. 
  • Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for malignant peritoneal mesothelioma: mitomycin versus cisplatin. 
  • Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy in patients with peritoneal hepatocellular carcinoma. 
  • Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia. 
  • DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study. 
  • Design and analysis of annular antenna arrays with different reflectors. 
  • Design of a water coupling bolus with improved flow distribution for multi-element superficial hyperthermia applicators. 
  • Determination of continuous atracurium infusion rate in dogs undergoing whole-body hyperthermia. 
  • Directional power deposition from direct-coupled and catheter-cooled interstitial ultrasound applicators. 
  • Do surgical clips interfere with radiofrequency thermal ablation? 
  • Drug targeting using thermally responsive polymers and local hyperthermia. 
  • Dual-mode IVUS catheter for intracranial image-guided hyperthermia: feasibility study. 
  • Dual-mode IVUS transducer for image-guided brain therapy: preliminary experiments. 
  • Dual-mode intracranial catheter integrating 3D ultrasound imaging and hyperthermia for neuro-oncology: feasibility study. 
  • Durable palliation of breast cancer chest wall recurrence with radiation therapy, hyperthermia, and chemotherapy. 
  • Dynamic contrast-enhanced magnetic resonance imaging as a predictor of clinical outcome in canine spontaneous soft tissue sarcomas treated with thermoradiotherapy. 
  • Early macular morphological changes following plaque radiotherapy for uveal melanoma. 
  • Effect of 5-hydroxytryptamine on tissue blood flow and microwave heating of rat tumors. 
  • Effect of calcitonin gene related peptide vs sodium nitroprusside to increase temperature in spontaneous canine tumours during local hyperthermia. 
  • Effect of complex bolus-tissue load configurations on SAR distributions from dual concentric conductor applicators. Specific absorption rate. 
  • Effect of hyperthermia on cisplatin pharmacokinetics in normal dogs. 
  • Effect of practical layered dielectric loads on SAR patterns from dual concentric conductor microstrip antennas. 
  • Effect of temperature on kainic acid-induced seizures. 
  • Effect of whole body hyperthermia on carboplatin disposition and toxicity in dogs. 
  • Effective learning strategies for real-time image-guided adaptive control of multiple-source hyperthermia applicators. 
  • Effects of glutathione or polyamine depletion on in vivo thermosensitization. 
  • Effects of hyperthermia and irradiation on the growth of mouse melanoma tumors following immunotherapy. 
  • Effects of hyperthermia in neutralising mechanisms of drug resistance in non-muscle-invasive bladder cancer. 
  • Effects of intraoperative irradiation and intraoperative hyperthermia on canine sciatic nerve: neurologic and electrophysiologic study. 
  • Effects of temperature changes on cerebral biochemistry in spontaneous intracerebral hematoma. 
  • Efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in the management of malignant ascites. 
  • Efficacy of hyperthermic isolated limb perfusion for extremity-confined recurrent melanoma. 
  • Electromagnetic thermal therapy power optimization for multiple source applicators. 
  • Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia. 
  • Enhanced tumour uptake of radiolabelled antibodies by hyperthermia. Part II: Application of the thermal equivalency equation. 
  • Enhanced tumour uptake of radiolabelled antibodies by hyperthermia: Part I: Timing of injection relative to hyperthermia. 
  • Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition. 
  • Enhancement of melphalan-induced gastrointestinal toxicity in mice treated with regional hyperthermia and BSO-mediated glutathione depletion. 
  • Enhancement of radiotherapy by hyperthermia-regulated gene therapy. 
  • EphrinA I-targeted nanoshells for photothermal ablation of prostate cancer cells. 
  • Estimation of cell survival in tumours heated to nonuniform temperature distributions. 
  • Estimation of therapeutic gain in clinical trials involving hyperthermia and radiotherapy. 
  • Evaluation of a dual-arm Archimedean spiral array for microwave hyperthermia. 
  • Experimental method for the hyperthermic treatment of cells in tissue culture: initial application to pancreatic cancer cells. 
  • Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy. 
  • Feasibility of estimating the temperature distribution in a tumor heated by a waveguide applicator. 
  • Ferromagnetic hyperthermia and iodine 125 brachytherapy in the treatment of choroidal melanoma in a rabbit model. 
  • First international association of hyperthermic oncology Tsudomu Sugahara award. 
  • Flow patterns and heat convection in a rectangular water bolus for use in superficial hyperthermia. 
  • Focal gene induction in the liver of rats by a heat-inducible promoter using focused ultrasound hyperthermia: preliminary results. 
  • Frequency-dependent absorption of electromagnetic energy in biological tissue. 
  • From the RSNA refresher courses: MR imaging in hyperthermia. 
  • Further justification for development of non-invasive thermometry. 
  • Future directions in hyperthermia biology. 
  • Gadolinium-conjugated gold nanoshells for multimodal diagnostic imaging and photothermal cancer therapy. 
  • Genitourinary resection at the time of cytoreductive surgery and heated intraperitoneal chemotherapy for peritoneal carcinomatosis is not associated with increased morbidity or worsened oncologic outcomes: a case-matched study. 
  • Gold nanoparticles-mediated photothermal therapy and immunotherapy. 
  • Heat induces gene amplification in cancer cells. 
  • Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity. 
  • Heat-targeted drug delivery: A promising approach for organsparing treatment of bladder cancer.THERMODOX®. 
  • Heating patterns generated by phase modulation of a hexagonal array of interstitial antennas. 
  • Hematometra after thermal balloon endometrial ablation in a patient with cervical incompetence. 
  • High intensity focused ultrasound-induced gene activation in solid tumors. 
  • Hyperthermia MRI temperature measurement: evaluation of measurement stabilisation strategies for extremity and breast tumours. 
  • Hyperthermia and intravesical therapy: emerging one-two punch for bladder cancer? 
  • Hyperthermia and liposomes. 
  • Hyperthermia as a treatment for bladder cancer. 
  • Hyperthermia as adjunct to intravesical chemotherapy for bladder cancer. 
  • Hyperthermia classic commentary: 'Arrhenius relationships from the molecule and cell to the clinic' by William Dewey, Int. J. Hyperthermia, 10:457-483, 1994. 
  • Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence: a review of the randomised data. 
  • Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. 
  • Hyperthermia for locally advanced breast cancer. 
  • Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas. 
  • Hyperthermia mediated liposomal drug delivery. 
  • Hyperthermia quality assurance guidelines. 
  • Hyperthermia treatment planning and temperature distribution reconstruction: a case study. 
  • Hyperthermia-induced enhancement of melphalan activity against a melphalan-resistant human rhabdomyosarcoma xenograft. 
  • Hyperthermia-regulated immunogene therapy. 
  • Hyperthermia: an overview of current progress and problems. 
  • Hyperthermic effects on behavior. 
  • Hyperthermic modulation of radiolabelled antibody uptake in a human glioma xenograft and normal tissues. 
  • Hyperthermic sensitization by the radical initiator 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH). I. In vitro studies. 
  • Hyperthermic treatment of malignant diseases: current status and a view toward the future. 
  • IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. 
  • Image-guided percutaneous thermal ablation for the palliative treatment of chest wall masses. 
  • Immunonanoshells for targeted photothermal ablation in medulloblastoma and glioma: an in vitro evaluation using human cell lines. 
  • Immunonanoshells for targeted photothermal ablation of tumor cells. 
  • Immunotargeted nanoshells for integrated cancer imaging and therapy. 
  • Impact of distal pancreatectomy on outcomes of peritoneal surface disease treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. 
  • Improved hyperthermia treatment control using SAR/temperature simulation and PRFS magnetic resonance thermal imaging. 
  • Improved magnetic resonance thermal imaging by combining proton resonance frequency shift (PRFS) and apparent diffusion coefficient (ADC) data. 
  • In regard to Vasanathan et al. (Int J Radiat Oncol Biol Phys 2005;61:145-153). 
  • In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery. 
  • In vivo particle tracking and photothermal ablation using plasmon-resonant gold nanostars. 
  • Induction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy. 
  • Integrated endoscope for real-time 3D ultrasound imaging and hyperthermia: feasibility study. 
  • Intersociety Council on Radiation Oncology essay on the introduction of new medical treatments into practice. 
  • Interstitial hyperthermia and iridium brachytherapy in treatment of malignant glioma. A phase I clinical trial. 
  • Interstitial irradiation and hyperthermia for the treatment of recurrent malignant brain tumors. 
  • Interstitial microwave hyperthermia in a canine brain model. 
  • Interstitial microwave-induced hyperthermia and iridium brachytherapy for the treatment of obstructing biliary carcinomas. 
  • Intra-peritoneal cisplatin and whole abdomen hyperthermia for relapsed ovarian carcinoma. 
  • Intracranial dual-mode IVUS and hyperthermia using circular arrays: preliminary experiments. 
  • Intraoperative interstitial microwave-induced hyperthermia and brachytherapy. 
  • Intraperitoneal chemotherapy for peritoneal surface malignancy: experience with 1,000 patients. 
  • Intraperitoneal cisplatin and regional hyperthermia for ovarian carcinoma. 
  • Intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: current status and future directions. 
  • Intraperitoneal hyperthermic chemotherapy: an evolving paradigm for the treatment of peritoneal surface malignancies. 
  • Inverse techniques in hyperthermia: a sensitivity study. 
  • Isolated limb infusion for in-transit malignant melanoma of the extremity: a well-tolerated but less effective alternative to hyperthermic isolated limb perfusion. 
  • Local 42 degrees C hyperthermia improves vascular conductance of the R3230Ac rat mammary adenocarcinoma during sodium nitroprusside infusion. 
  • Local control and distant metastases in primary canine malignant melanomas treated with hyperthermia and/or radiotherapy. 
  • Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model. 
  • MRI-guided radiofrequency thermal ablation of implanted VX2 liver tumors in a rabbit model: demonstration of feasibility at 0.2 T. 
  • Magnetic fluid hyperthermia for bladder cancer: a preclinical dosimetry study. 
  • Magnetic induction heating of ferromagnetic implants for inducing localized hyperthermia in deep-seated tumors. 
  • Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects. 
  • Magnetic resonance imaging: a potential tool in assessing the addition of hyperthermia to neoadjuvant therapy in patients with locally advanced breast cancer. 
  • Magnetic resonance thermometry during hyperthermia for human high-grade sarcoma. 
  • Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia. 
  • Marked variability of melphalan plasma drug levels during regional hyperthermic isolated limb perfusion. 
  • Mathematical formulation and analysis of the nonlinear system reconstruction of the online image-guided adaptive control of hyperthermia. 
  • Microwave hyperthermia and its effect on tumor blood flow in rats. 
  • Microwave hyperthermia for choroidal melanoma in rabbits. 
  • Miniature microwave applicator for murine bladder hyperthermia studies. 
  • Minimally invasive intra-arterial regional therapy for metastatic melanoma: isolated limb infusion and percutaneous hepatic perfusion. 
  • Modelling aperture antennas in the near- and far-field regions using subarrays of equivalent uniformly illuminated apertures. 
  • Modest advances in survival for patients with colorectal-associated peritoneal carcinomatosis in the era of modern chemotherapy. 
  • Monitoring health outcomes following cytoreductive surgery plus intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis. 
  • Monitoring of neoadjuvant therapy response of soft-tissue and musculoskeletal sarcoma using fluorine-18-FDG PET. 
  • Monitoring the jugular-venous oxyhemoglobin saturation as a decision aid for normothermic cardiopulmonary bypass. 
  • Multi-spin echo spatial encoding provides three-fold improvement of temperature precision during intermolecular zero quantum thermometry. 
  • Multilayer conformal applicator for microwave heating and brachytherapy treatment of superficial tissue disease. 
  • NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment. 
  • Nanoparticles for thermal cancer therapy. 
  • Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. 
  • Non-invasive monitoring of intra-tumor drug concentration and therapeutic response using optical spectroscopy. 
  • Non-invasive thermometry using magnetic resonance diffusion imaging: potential for application in hyperthermic oncology. 
  • Non-invasive, quantitative monitoring of hyperthermia-induced EGFR activation in xenograft tumours. 
  • Nonuniform alteration of cis-diamminedichloroplatinum(II) tissue distribution in dogs with whole body hyperthermia. 
  • Novel approaches to treatment of hepatocellular carcinoma and hepatic metastases using thermal ablation and thermosensitive liposomes. 
  • Obesity and peritoneal surface disease: outcomes after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for appendiceal and colon primary tumors. 
  • Observations on the use of ferromagnetic implants for inducing hyperthermia. 
  • Ocular Surface Parameters Predicting Patient Satisfaction After a Single Vectored Thermal Pulsation Procedure for Management of Symptomatic Meibomian Gland Dysfunction. 
  • On the accuracy of noninvasive thermometry using molecular diffusion magnetic resonance imaging. 
  • Online feedback focusing algorithm for hyperthermia cancer treatment. 
  • Opportunities for near-infrared thermal ablation of colorectal metastases by guanylyl cyclase C-targeted gold nanoshells. 
  • Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity. 
  • Optimizing regional infusion treatment strategies for melanoma of the extremities. 
  • Optimizing regional therapy for melanoma. 
  • Outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface dissemination from ovarian neoplasms. 
  • Outcomes associated with cytoreductive surgery and intraperitoneal hyperthermic chemotherapy in colorectal cancer patients with peritoneal surface disease and hepatic metastases. 
  • Outcomes for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the elderly. 
  • Outcomes of Cytoreductive Surgery (CRS) with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients Older than 70 Years; Survival Benefit at Considerable Morbidity and Mortality: A Reply. 
  • Outcomes of Cytoreductive Surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients older than 70 years; survival benefit at considerable morbidity and mortality. 
  • Outcomes of Thermal Pulsation Treatment for Dry Eye Syndrome in Patients With Sjogren Disease. 
  • Outcomes of repeat cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal surface malignancy. 
  • Outcomes with cytoreductive surgery and HIPEC for peritoneal metastasis. 
  • Patient selection for cytoreduction and hyperthermic intraperitoneal chemoperfusion. 
  • Patterns of recurrence following complete response to regional chemotherapy for in-transit melanoma. 
  • Performance evaluation of a conformal thermal monitoring sheet sensor array for measurement of surface temperature distributions during superficial hyperthermia treatments. 
  • Perioperative systemic chemotherapy for appendiceal mucinous carcinoma peritonei treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. 
  • Peritoneal carcinomatosis in patients with gastric cancer, and the role for surgical resection, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy. 
  • Peritoneal surface disease (PSD) from appendiceal cancer treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC): overview of 481 cases. 
  • Peritoneal surface disease from colorectal cancer: comparison with the hepatic metastases surgical paradigm in optimally resected patients. 
  • Peritoneal surface disease with synchronous hepatic involvement treated with Cytoreductive Surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). 
  • Perturbations in hyperthermia temperature distributions associated with counter-current flow: numerical simulations and empirical verification. 
  • Pharmacokinetics & drug resistance of melphalan in regional chemotherapy: ILP versus ILI. 
  • Pharmacokinetics and toxicity of intraperitoneal cisplatin combined with regional hyperthermia. 
  • Pharmacokinetics of combined gene therapy expressing constitutive human GM-CSF and hyperthermia-regulated human IL-12. 
  • Phase I evaluation of doxorubicin and whole-body hyperthermia in dogs with lymphoma. 
  • Phase I study of melphalan alone and melphalan plus whole body hyperthermia in dogs with malignant melanoma. 
  • Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors. 
  • Phase I/II trial of intravenous Doxil and whole abdomen hyperthermia in patients with refractory ovarian cancer. 
  • Phase III evaluation of doxorubicin and whole-body hyperthermia in dogs with lymphoma. 
  • Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles. 
  • Physiological mechanisms underlying heat-induced radiosensitization. 
  • Practical induction heating coil designs for clinical hyperthermia with ferromagnetic implants. 
  • Preclinical assessment of comfort and secure fit of thermobrachytherapy surface applicator (TBSA) on volunteer subjects. 
  • Predicting postoperative morbidity following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CS+HIPEC) with preoperative FACT-C (Functional Assessment of Cancer Therapy) and patient-rated performance status. 
  • Predictors of outcome after hyperthermic isolated limb perfusion: role of tumor response. 
  • Progress toward a thermal dosimetry system. 
  • Prospective assessment of quality of life in ovarian cancer patients receiving whole abdomen hyperthermia and liposomal doxorubicin. 
  • Prospective thermal dosimetry: the key to hyperthermia's future. 
  • Pulmonary toxicity after intraperitoneal mitomycin C: a case report of a rare complication of HIPEC. 
  • Pulsatile blood flow effects on temperature distribution and heat transfer in rigid vessels. 
  • Quantitative estimation of the thermal dose-modifying factor for cis-diamminedichloroplatinum (CDDP) in tumour-bearing dogs. 
  • ROS production and angiogenic regulation by macrophages in response to heat therapy. 
  • RTOG quality assurance guidelines for clinical trials using hyperthermia for deep-seated malignancy. 
  • RTOG quality assurance guidelines for clinical trials using hyperthermia. 
  • RTOG quality assurance guidelines for interstitial hyperthermia. 
  • Radiation dosimetry of a conformal heat-brachytherapy applicator. 
  • Radiation patterns of dual concentric conductor microstrip antennas for superficial hyperthermia. 
  • Radiation plus local hyperthermia versus radiation plus the combination of local and whole-body hyperthermia in canine sarcomas. 
  • Radiation therapy and hyperthermia improve the oxygenation of human soft tissue sarcomas. 
  • Radiofrequency ablation: the effect of distance and baseline temperature on thermal dose required for coagulation. 
  • Randomized multicenter trial of hyperthermic isolated limb perfusion with melphalan alone compared with melphalan plus tumor necrosis factor: American College of Surgeons Oncology Group Trial Z0020. 
  • Randomized trial of hyperthermia and radiation for superficial tumors. 
  • Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors. 
  • Rationale for and measurement of liposomal drug delivery with hyperthermia using non-invasive imaging techniques. 
  • Re-setting the biologic rationale for thermal therapy. 
  • Re: Kapp editorial IJROBP 35:189-194; 1996. 
  • Real-time MRI-guided hyperthermia treatment using a fast adaptive algorithm. 
  • Regional hyperthermia by magnetic induction in a beagle dog model: analysis of thermal dosimetry. 
  • Regression of uveal melanoma after plaque radiotherapy and thermotherapy based on chromosome 3 status. 
  • Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy. 
  • Relationships among tumor temperature, treatment time, and histopathological outcome using preoperative hyperthermia with radiation in soft tissue sarcomas. 
  • Response of canine oral carcinomas to heat and radiation. 
  • Response of canine soft tissue sarcomas to radiation or radiation plus hyperthermia: a randomized phase II study. 
  • Restoration of foveal anatomy and function following chemoreduction for bilateral advanced retinoblastoma with total retinal detachment. 
  • Retinal tear and detachment after transpupillary thermotherapy for choroidal melanoma. 
  • Routine Admission to Intensive Care Unit After Cytoreductive Surgery and Heated Intraperitoneal Chemotherapy: Not Always a Requirement. 
  • SAR pattern perturbations from resonance effects in water bolus layers used with superficial microwave hyperthermia applicators. 
  • Sensitivity of hyperthermia trial outcomes to temperature and time: implications for thermal goals of treatment. 
  • Serious toxicity associated with annular microwave array induction of whole-body hyperthermia in normal dogs. 
  • Serum biomarker profiles and response to neoadjuvant chemotherapy for locally advanced breast cancer. 
  • Should interstitial thermometry be used for deep hyperthermia? 
  • Significance of diabetes on morbidity and mortality following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. 
  • Significance of diaphragmatic resections and thoracic chemoperfusion on outcomes of peritoneal surface disease treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). 
  • Significance of urinary tract involvement in patients treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). 
  • Simulation of electromagnetically induced hyperthermia: a finite element gridding method. 
  • Simulation techniques in hyperthermia treatment planning. 
  • Soft-tissue sarcomas: MR imaging and MR spectroscopy for prognosis and therapy monitoring. Work in progress. 
  • Survival and quality of life following cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colonic origin. 
  • Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme. 
  • Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the Treatment of Unresectable and Metastatic Cancers. 
  • Systemic anti-tumour effects of local thermally sensitive liposome therapy. 
  • TAT peptide-functionalized gold nanostars: enhanced intracellular delivery and efficient NIR photothermal therapy using ultralow irradiance. 
  • Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia. 
  • Technological Advances, Biologic Rationales, and the Associated Success of Chemotherapy With Hyperthermia in Improved Outcomes in Patients With Sarcoma. 
  • Temperature dependence of canine brain tissue diffusion coefficient measured in vivo with magnetic resonance echo-planar imaging. 
  • Temperature matters! And why it should matter to tumor immunologists. 
  • Temperature measurements in normal and tumor tissue of dogs undergoing whole body hyperthermia. 
  • Temperature sensitive peptides: engineering hyperthermia-directed therapeutics. 
  • Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment. 
  • The effects of clinically relevant hyperthermic temperatures on the kinetic binding parameters of a monoclonal antibody. 
  • The effects of hyperthermia and hyperthermia plus microwaves on rat brain energy metabolism. 
  • The effects of local hyperthermia on the catabolism of a radioiodinated chimeric monoclonal antibody. 
  • The endoscopic radiofrequency approach to management of GERD. 
  • The future of biology in driving the field of hyperthermia. 
  • The impact of temperature and urinary constituents on urine viscosity and its relevance to bladder hyperthermia treatment. 
  • The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz. 
  • The performance of a reduced-order adaptive controller when used in multi-antenna hyperthermia treatments with nonlinear temperature-dependent perfusion. 
  • The role of a combined regimen with intravesical chemotherapy and hyperthermia in the management of non-muscle-invasive bladder cancer: a systematic review. 
  • The role of hyperthermia in regional alkylating agent chemotherapy. 
  • The treatment of high-grade soft tissue sarcomas with preoperative thermoradiotherapy. 
  • The use of hyperthermia in the treatment of bladder cancer. 
  • The utility of thermal dose as a predictor of tumor and normal tissue responses to combined radiation and hyperthermia. 
  • Theoretical and measured electric field distributions within an annular phased array: consideration of source antennas. 
  • Theoretical characterization of dual concentric conductor microwave applicators for hyperthermia at 433 MHz. 
  • Therapy monitoring in human and canine soft tissue sarcomas using magnetic resonance imaging and spectroscopy. 
  • Thermal and SAR characterization of multielement dual concentric conductor microwave applicators for hyperthermia, a theoretical investigation. 
  • Thermal characteristics of thermobrachytherapy surface applicators for treating chest wall recurrence. 
  • Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors. 
  • Thermal dose fractionation affects tumour physiological response. 
  • Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy. 
  • Thermal dosimetry characteristics of deep regional heating of non-muscle invasive bladder cancer. 
  • Thermal dosimetry for bladder hyperthermia treatment. An overview. 
  • Thermal medicine, heat shock proteins and cancer. 
  • Thermoradiotherapy of recurrent malignant brain tumors. 
  • Those in gene therapy should pay closer attention to lessons from hyperthermia. 
  • Those in gene therapy should pay closer attention to lessons from hyperthermia. 
  • Thresholds for thermal damage to normal tissues: an update. 
  • Transient finite element analysis of thermal methods used to estimate SAR and blood flow in homogeneously and nonhomogeneously perfused tumour models. 
  • Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review. 
  • Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice. 
  • Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome. 
  • Tumor temperature distributions predict hyperthermia effect. 
  • Tumour cell kinetics as predictors of response in canine lymphoma treated with chemotherapy alone or combined with whole body hyperthermia. 
  • Two approaches for enhancing radioimmunotherapy: alpha emitters and hyperthermia. 
  • Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer. 
  • Ultrasound guided pO2 measurement of breast cancer reoxygenation after neoadjuvant chemotherapy and hyperthermia treatment. 
  • Unfocused laser illumination kills dye-targeted mouse neurons by selective photothermolysis. 
  • Use of nitroprusside to increase tissue temperature during local hyperthermia in normal and tumor-bearing dogs. 
  • Use of radiation and/or hyperthermia for treatment of mast cell tumors and lymphosarcoma in dogs. 
  • Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses. 
  • Using units of CEM 43 degrees C T90, local hyperthermia thermal dose can be delivered as prescribed. 
  • Utility of functional imaging in prediction or assessment of treatment response and prognosis following thermotherapy. 
  • Utility of treatment planning for thermochemotherapy treatment of nonmuscle invasive bladder carcinoma. 
  • Variations of focal regions versus numbers and positions of sources in two-dimensional media. 
  • Vascular-targeted photothermal therapy of an orthotopic murine glioma model. 
  • Vascularized tissue transfer for closure of irradiated wounds after soft tissue sarcoma resection. 
  • Verification of a hyperthermia model method using MR thermometry. 
  • Vesicoureteral reflux in children: a phantom study of microwave heating and radiometric thermometry of pediatric bladder. 
  • What potential does plasmonics-amplified synergistic immuno photothermal nanotherapy have for treatment of cancer? 
  • Where there's smoke, is there fire? 
  • Whole body hyperthermia and heat-sensitizing drugs: a pilot study in canine lymphoproliferative disease. 
  • Whole body hyperthermia in dogs using a radiant heating device: effect of surface cooling on temperature uniformity. 
  • Whole-body hyperthermia. Rationale and potential use for cancer treatment. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Charles, Hal Cecil, Associate Professor of Radiology, Radiology
  • Craciunescu, Oana, Associate Professor of Radiation Oncology, Radiation Oncology
  • Palmer, Gregory M., Associate Professor of Radiation Oncology, Radiation Oncology
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic