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Subject Areas on Research
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2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
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2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
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A Planar Culture Model of Human Absorptive Enterocytes Reveals Metformin Increases Fatty Acid Oxidation and Export.
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A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function.
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A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection.
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A futile metabolic cycle activated in adipocytes by antidiabetic agents.
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A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
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A primer on concentrated insulins: what an internist should know.
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A quantitative measure of diabetes risk in community practice impacts clinical decisions: the PREVAIL initiative.
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A retrospective cohort study of economic outcomes and adherence to monotherapy with metformin, pioglitazone, or a sulfonylurea among patients with type 2 diabetes mellitus in the United States from 2003 to 2005.
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ASPIRE-2-PREVENT: a survey of lifestyle, risk factor management and cardioprotective medication in patients with coronary heart disease and people at high risk of developing cardiovascular disease in the UK.
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Acanthosis nigricans: a practical approach to evaluation and management.
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Accuracy and Longevity of an Implantable Continuous Glucose Sensor in the PRECISE Study: A 180-Day, Prospective, Multicenter, Pivotal Trial.
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Acetaminophen normalizes glucose homeostasis in mouse models for diabetes.
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Activated α2-macroglobulin binding to human prostate cancer cells triggers insulin-like responses.
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Adherence to Guidelines for Screening and Medication Use: Mortality and Onset of Major Macrovascular Complications in Elderly Persons With Diabetes Mellitus.
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Adherence to diabetes guidelines for screening, physical activity and medication and onset of complications and death.
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Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis.
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Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.
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Alcohol-associated risks for young adults with Type 1 diabetes: a narrative review.
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Alterations in calcium channel currents underlie defective insulin secretion in a transgenic mouse.
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Alzheimer’s disease: the new promise.
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An outcome model approach to transporting a randomized controlled trial results to a target population.
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Antidiabetic drug therapy of African-American and white community-dwelling elderly over a 10-year period.
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Antidiabetic therapies affect risk of pancreatic cancer.
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Antihyperglycemic Medication Use Among Medicare Beneficiaries With Heart Failure, Diabetes Mellitus, and Chronic Kidney Disease.
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Antihyperglycemic Therapies to Treat Patients With Heart Failure and Diabetes Mellitus.
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Antithrombotic treatment gap among patients with atrial fibrillation and type 2 diabetes.
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Are sulfonylureas passé?
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Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness.
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Assessing the Safety of Sitagliptin in Older Participants in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS).
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Association between diabetes mellitus and post-discharge outcomes in patients hospitalized with heart failure: findings from the EVEREST trial.
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Association between glycated haemoglobin levels and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease: a secondary analysis of the TECOS randomized clinical trial.
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Association of Adverse Pregnancy Outcomes With Glyburide vs Insulin in Women With Gestational Diabetes.
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Association of Prenatal Care Expansion With Use of Antidiabetic Agents During Pregnancies Among Latina Emergency Medicaid Recipients With Gestational Diabetes.
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Association of diabetes mellitus and glycemic control strategies with clinical outcomes after acute coronary syndromes.
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Association of diabetes mellitus and glycemic control strategies with clinical outcomes after acute coronary syndromes.
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Association of obesity with cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease: Insights from TECOS.
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Associations between β-blocker therapy and cardiovascular outcomes in patients with diabetes and established cardiovascular disease.
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Atherosclerotic disease in non-insulin-dependent diabetes mellitus: role of abnormal lipids and the place for lipid-altering therapies.
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Automated Insulin Delivery Systems: Hopes and Expectations of Family Members.
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Automated bolus advisor control and usability study (ABACUS): does use of an insulin bolus advisor improve glycaemic control in patients failing multiple daily insulin injection (MDI) therapy? [NCT01460446].
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Avoidance of weight gain is important for oral type 2 diabetes treatments in Sweden and Germany: patient preferences.
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BARI 2D: A Reanalysis Focusing on Cardiovascular Events.
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Barriers to prescribing glucose-lowering therapies with cardiometabolic benefits.
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Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).
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Baseline predictors of A1C reduction in adults using sensor-augmented pump therapy or multiple daily injection therapy: the STAR 3 experience.
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Be Careful What You Ask For: Effects of Benefit Descriptions on Diabetes Patients' Benefit-Risk Tradeoff Preferences.
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Bed rest worsens impairments in fat and glucose metabolism in older, overweight adults.
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Blood Pressure Control and the Association With Diabetes Mellitus Incidence: Results From SPRINT Randomized Trial.
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CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice.
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CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes.
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Capitalizing on prescribing pattern variation to compare medications for type 2 diabetes.
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Capsule Commentary on Min et al., Comparative Effectiveness of Insulin versus Combination Sulfonylurea and Insulin: a Cohort Study of Veterans with Type 2 Diabetes: How to Escalate Therapy for Patients who Fail Sulfonylureas.
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Cardiovascular Outcome Trial Update in Diabetes: New Evidence, Remaining Questions.
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Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From a Diabetes Care Editors' Expert Forum.
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Cardiovascular and Renal Outcomes with Efpeglenatide in Type 2 Diabetes.
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Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis.
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Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials.
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Causes of Death in a Contemporary Cohort of Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: Insights From the TECOS Trial.
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Central and peripheral effects of insulin/IGF-1 signaling in aging and cancer: antidiabetic drugs as geroprotectors and anticarcinogens.
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Challenges of optimizing glycaemic control in children with Type 1 diabetes: a qualitative study of parents' experiences and views.
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Changes in depressive symptoms and glycemic control in diabetes mellitus.
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Characteristics of clinical trials evaluating cardiovascular therapies for Coronavirus Disease 2019 Registered on ClinicalTrials.gov: a cross sectional analysis.
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Clinical Impact of Diabetes Mellitus on Outcomes After Transcatheter Aortic Valve Replacement: Insights From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.
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Clinical Outcomes in Patients With Type 2 Diabetes Mellitus and Peripheral Artery Disease: Results From the EXSCEL Trial.
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Clinical Outcomes of Metformin Use in Populations With Chronic Kidney Disease, Congestive Heart Failure, or Chronic Liver Disease: A Systematic Review.
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Clinical Phenotypes in Patients With Type 2 Diabetes Mellitus: Characteristics, Cardiovascular Outcomes and Treatment Strategies.
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Clinical associations of an updated medication effect score for measuring diabetes treatment intensity.
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Clinical correlates of histopathology in pediatric nonalcoholic steatohepatitis.
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Clinical pharmacology of benoxaprofen.
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Clinical pharmacology of insulin confounds stroke trials.
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Clinical progress note: Indications for and management of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in hospitalized patients.
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Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome.
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Closing the Loop in Adults, Children and Adolescents With Suboptimally Controlled Type 1 Diabetes Under Free Living Conditions: A Psychosocial Substudy.
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Combination insulin and sulfonylurea therapy in insulin-requiring type 2 diabetes mellitus.
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Comment on Davis et al. Effects of Severe Hypoglycemia on Cardiovascular Outcomes and Death in the Veterans Affairs Diabetes Trial. Diabetes Care 2019;42:157-163.
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Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations.
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Comparing off-pump and on-pump clinical outcomes and costs for diabetic cardiac surgery patients.
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Comparing the effects of ipragliflozin versus metformin on visceral fat reduction and metabolic dysfunction in Japanese patients with type 2 diabetes treated with sitagliptin: A prospective, multicentre, open-label, blinded-endpoint, randomized controlled study (PRIME-V study).
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Comparison of Group Medical Visits Combined With Intensive Weight Management vs Group Medical Visits Alone for Glycemia in Patients With Type 2 Diabetes: A Noninferiority Randomized Clinical Trial.
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Comparison of an Electronic Glycemic Management System Versus Provider-Managed Subcutaneous Basal Bolus Insulin Therapy in the Hospital Setting.
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Comparison of insulin glargine and liraglutide added to oral agents in patients with poorly controlled type 2 diabetes.
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Comparison of one-year outcomes following coronary artery stenting in diabetic versus nondiabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy [ESPRIT] Trial).
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Confirming the Bidirectional Nature of the Association Between Severe Hypoglycemic and Cardiovascular Events in Type 2 Diabetes: Insights From EXSCEL.
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Contemporary Medical Therapies for Patients with Peripheral Artery Disease and Concomitant Type 2 Diabetes Mellitus: a Review of Current Evidence.
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Controlled release of biologics for the treatment of type 2 diabetes.
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Controversial Issues: When the drugs don't work, can surgery provide a different outcome for diabetic adolescents?
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Coordinate regulation of the alpha(2)-macroglobulin signaling receptor and the low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor by insulin.
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Coordinating Cardiology clinics randomized trial of interventions to improve outcomes (COORDINATE) - Diabetes: rationale and design.
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Corrections needed to 2016 ESC and AHA guidelines on heart failure.
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Cost-effectiveness of diabetes treatment sequences to inform step therapy policies.
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Cost-effectiveness of sensor-augmented pump therapy in adults with type 1 diabetes in the United States.
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Current cardiovascular outcomes trials in type 2 diabetes: Perspectives and insight.
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Current practices in gestational diabetes mellitus diagnosis and management in the United States: survey of maternal-fetal medicine specialists.
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DCRM Multispecialty Practice Recommendations for the management of diabetes, cardiorenal, and metabolic diseases.
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Day-and-Night Closed-Loop Insulin Delivery in a Broad Population of Pregnant Women With Type 1 Diabetes: A Randomized Controlled Crossover Trial.
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Deintensification of Treatment With Sulfonylurea and Insulin After Severe Hypoglycemia Among Older Adults With Diabetes.
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Depression in persons with diabetes by age and antidiabetic treatment: a cross-sectional analysis with data from the Hordaland Health Study.
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Determinants of successful glycemic control among participants in the BARI 2D trial: a post-hoc analysis.
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Diabetes Technology and the Human Factor.
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Diabetes medication regimens and patient clinical characteristics in the national patient-centered clinical research network, PCORnet.
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Diabetes mellitus and insulin therapy in infective endocarditis.
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Diabetes on a cardiovascular ward: adherence to current recommendations.
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Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer.
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Diabetic kidney disease: a report from an ADA Consensus Conference.
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Dietary Insulin Load and Cancer Recurrence and Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803 (Alliance).
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Dietary treatment of diabetes mellitus in the pre-insulin era (1914-1922).
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Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats.
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Differential AMPK phosphorylation by glucagon and metformin regulates insulin signaling in human hepatic cells.
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Dipeptidyl-peptidase-4 inhibitors and pancreatic cancer: a cohort study.
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Direct antidiabetic effect of leptin through triglyceride depletion of tissues.
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Discontinuation of diabetes and lipid-lowering medications after bariatric surgery at Veterans Affairs medical centers.
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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.
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Does medication adherence following a copayment increase differ by disease burden?
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Does the presence of a pharmacist in primary care clinics improve diabetes medication adherence?
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Duration of type 2 diabetes does not appear to moderate hypoglycaemia rate with insulin degludec versus insulin glargine U100.
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Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial.
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Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial.
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Effect of Medicaid Policy Changes on Medication Adherence: Differences by Baseline Adherence.
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Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes Mellitus With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial.
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Effect of Once-Weekly Exenatide on Clinical Outcomes According to Baseline Risk in Patients With Type 2 Diabetes Mellitus: Insights From the EXSCEL Trial.
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Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes.
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Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOS.
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Effect of intracerebroventricular infusion of insulin on glucose-dependent insulinotropic peptide in dogs.
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Effect of once-weekly exenatide on hospitalization for acute coronary syndrome or coronary revascularization in patients with type 2 diabetes mellitus.
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Effect of predicted low suspend pump treatment on improving glycaemic control and quality of sleep in children with type 1 diabetes and their caregivers: the QUEST randomized crossover study.
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Effect of race on cardiometabolic responses to once-weekly exenatide: insights from the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).
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Effect of race on the glycaemic response to sitagliptin: Insights from the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS).
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Effectively identifying the inpatient with hyperglycemia to increase patient care and lower costs.
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Effects of Linagliptin on Cardiovascular and Kidney Outcomes in People With Normal and Reduced Kidney Function: Secondary Analysis of the CARMELINA Randomized Trial.
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Effects of Liraglutide on Cardiovascular Outcomes in Type 2 Diabetes Patients With and Without Baseline Metformin Use: Post Hoc Analyses of the LEADER Trial.
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Effects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial.
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Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.
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Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes.
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Effects of changes in potassium with valsartan use on diabetes risk: Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial.
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Effects of intensive glucose lowering in type 2 diabetes.
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Effects of ipragliflozin versus metformin in combination with sitagliptin on bone and muscle in Japanese patients with type 2 diabetes mellitus: Subanalysis of a prospective, randomized, controlled study (PRIME-V study).
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Effects of phentermine and phenformin on biomarkers of aging in rats.
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Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial.
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Efficacy and Safety of the Glucagon Receptor Antagonist RVT-1502 in Type 2 Diabetes Uncontrolled on Metformin Monotherapy: A 12-Week Dose-Ranging Study.
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Efficacy and safety of acarbose in metformin-treated patients with type 2 diabetes.
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Efficacy and safety of dapagliflozin in acute heart failure: Rationale and design of the DICTATE-AHF trial.
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Efficacy of metformin and fermentable fiber combination therapy in adolescents with severe obesity and insulin resistance: study protocol for a double-blind randomized controlled trial.
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Efpeglenatide and Clinical Outcomes With and Without Concomitant Sodium-Glucose Cotransporter-2 Inhibition Use in Type 2 Diabetes: Exploratory Analysis of the AMPLITUDE-O Trial.
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Eligibility of sodium-glucose co-transporter-2 inhibitors among patients with diabetes mellitus admitted for heart failure.
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Eligibility varies among the 4 sodium-glucose cotransporter-2 inhibitor cardiovascular outcomes trials: implications for the general type 2 diabetes US population.
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Enhanced Glucose Control Following Vertical Sleeve Gastrectomy Does Not Require a β-Cell Glucagon-Like Peptide 1 Receptor.
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Enhancement of endocrine pancreatic secretions by essential fatty acids.
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Exenatide and rimonabant: new treatments that may be useful in the management of diabetes and obesity.
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Exendin-4 increases blood glucose levels acutely in rats by activation of the sympathetic nervous system.
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Exploring the Possible Impact of Unbalanced Open-Label Drop-In of Glucose-Lowering Medications on EXSCEL Outcomes.
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Exploring the Relationship Between Efpeglenatide Dose and Cardiovascular Outcomes in Type 2 Diabetes: Insights From the AMPLITUDE-O Trial.
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Factors associated with insulin and narcotic independence after islet autotransplantation in patients with severe chronic pancreatitis.
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Factors associated with non-adherence to insulin and non-insulin medications in patients with poorly controlled diabetes.
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Factors influencing diabetes self-management in Chinese people with type 2 diabetes.
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Fear of hypoglycaemia in parents of young children with type 1 diabetes: a systematic review.
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Fibroblast growth factor 21 mediates specific glucagon actions.
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From Prescription to Transcription: Genome Sequence as Drug Target.
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Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action.
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GLP-1 agonist therapy for advanced heart failure with reduced ejection fraction: design and rationale for the functional impact of GLP-1 for heart failure treatment study.
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GLP-1 and energy balance: an integrated model of short-term and long-term control.
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GLP1 receptor agonists: from antihyperglycaemic to cardiovascular drugs.
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GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain.
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Gaps in Evidence-Based Therapy Use in Insured Patients in the United States With Type 2 Diabetes Mellitus and Atherosclerotic Cardiovascular Disease.
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Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes.
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Generalizability of glucagon-like peptide-1 receptor agonist cardiovascular outcome trials enrollment criteria to the US type 2 diabetes population.
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Glucagon receptor as a drug target: A witches' brew of eye of newt (peptides) and toe of frog (receptors).
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Glucagon-like peptide 1 (GLP-1).
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Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin.
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Glucose control in hospitalized patients.
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Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes.
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Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease.
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Glycemic Variability and Its Impact on Quality of Life in Adults With Type 1 Diabetes.
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Glycemic control in patients undergoing coronary artery bypass graft surgery: Clinical features, predictors, and outcomes.
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Glycemic management in diabetes and the associated cardiovascular risk: are we helping or hurting our patients?
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Guidelines for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes: JACC Guideline Comparison.
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Gut hormone pharmacology of a novel GPR119 agonist (GSK1292263), metformin, and sitagliptin in type 2 diabetes mellitus: results from two randomized studies.
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Gut peptides in the treatment of diabetes mellitus.
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Harmony Outcomes: A randomized, double-blind, placebo-controlled trial of the effect of albiglutide on major cardiovascular events in patients with type 2 diabetes mellitus-Rationale, design, and baseline characteristics.
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Heart failure event definitions in drug trials in patients with type 2 diabetes.
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Heterogeneity of Treatment Effects Among Patients With Type 2 Diabetes and Elevated Body Mass Index in a Study Comparing Group Medical Visits Focused on Weight Management and Medication Intensification.
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Heterogeneity of diabetes as a risk factor for major adverse cardiovascular events in anticoagulated patients with atrial fibrillation: an analysis of the ARISTOTLE trial.
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High hemoglobin A1c associated with increased adverse limb events in peripheral arterial disease patients undergoing revascularization.
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High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats.
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History of and factors associated with diabetic foot ulcers in Norway: the Nord-Trøndelag Health Study.
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History of hypertension, heart disease, and diabetes and ovarian cancer patient survival: evidence from the ovarian cancer association consortium.
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Home Use of an Artificial Beta Cell in Type 1 Diabetes.
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Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study.
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Hypertension Control in Adults With Diabetes Mellitus and Recurrent Cardiovascular Events: Global Results From the Trial Evaluating Cardiovascular Outcomes With Sitagliptin.
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Hypoglycemia Communication in Primary Care Visits for Patients with Diabetes.
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ISPAD Guidelines. Managing diabetes in preschool children.
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Impact of Chronic Sleep Disturbance for People Living With T1 Diabetes.
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Impact of Insurance Status on Outcomes and Use of Rehabilitation Services in Acute Ischemic Stroke: Findings From Get With The Guidelines-Stroke.
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Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions.
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Impact of Standardized Simulated Patients on First-Year Pharmacy Students' Knowledge Retention of Insulin Injection Technique and Counseling Skills.
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Impact of baseline insulin regimen on glycemic response to a group medical clinic intervention.
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Impact of emerging health insurance arrangements on diabetes outcomes and disparities: rationale and study design.
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Impact of glycemic control strategies on the progression of diabetic peripheral neuropathy in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Cohort.
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Impact of metformin use on the cardiovascular effects of dipeptidyl peptidase-4 inhibitors: An analysis of Medicare claims data from 2007 to 2015.
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Impact of the Discordance Between the American College of Cardiology/American Heart Association and American Diabetes Association Recommendations on Hypertension in Patients With Diabetes Mellitus in the United States.
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Importance of perioperative glycemic control in general surgery: a report from the Surgical Care and Outcomes Assessment Program.
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Improved glycemic control enhances the incretin effect in patients with type 2 diabetes.
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Improvements in health-related quality of life with liraglutide 3.0 mg compared with placebo in weight management.
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Improving blood pressure control through a clinical pharmacist outreach program in patients with diabetes mellitus in 2 high-performing health systems: the adherence and intensification of medications cluster randomized, controlled pragmatic trial.
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Improving the prediction of medication compliance: the example of bisphosphonates for osteoporosis.
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In CV disease, GLP-1 RAs and SGLT2 inhibitors reduce CV mortality.
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In-Hospital Initiation of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Reduced Ejection Fraction.
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Incidence of atrial fibrillation in a population with impaired glucose tolerance: the contribution of glucose metabolism and other risk factors. A post hoc analysis of the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial.
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Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle.
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Increasing copayments and adherence to diabetes, hypertension, and hyperlipidemic medications.
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Incretin mimetics as emerging treatments for type 2 diabetes.
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Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat-Fed Diabetic Mice.
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Initial injectable therapy in type 2 diabetes: Key considerations when choosing between glucagon-like peptide 1 receptor agonists and insulin.
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Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin.
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Insulin and longevity: antidiabetic biguanides as geroprotectors.
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Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen.
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Insulin pump therapy in toddlers and preschool children with type 1 diabetes mellitus.
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Insulin reverses the high-fat diet-induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease.
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Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction.
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Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial.
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Intensive insulin therapy and mortality in critically ill patients.
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Intensive insulin therapy in the neurocritical care setting is associated with poor clinical outcomes.
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International Variation in Outcomes Among People with Cardiovascular Disease or Cardiovascular Risk Factors and Impaired Glucose Tolerance: Insights from the NAVIGATOR Trial.
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International variation in characteristics and clinical outcomes of patients with type 2 diabetes and heart failure: Insights from TECOS.
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Interventions for Diabetic Retinopathy in Type 1 Diabetes: Systematic Review and Meta-Analysis.
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Intraarterial Microdosing: A Novel Drug Development Approach, Proof-of-Concept PET Study in Rats.
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Is iatrogenic sleep disturbance worth the effort in Type 1 diabetes?
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Islet α cells and glucagon--critical regulators of energy homeostasis.
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Isoflurane, but not halothane, induces protection of human myocardium via adenosine A1 receptors and adenosine triphosphate-sensitive potassium channels.
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JCL Roundtable. Obesity, Diabetes, and Liver Disease in Relation to Cardiovascular Risk.
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Jump starting shared medical appointments for diabetes with weight management: Rationale and design of a randomized controlled trial.
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LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.
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Lifetime cost-effectiveness simulation of once-weekly exenatide in type 2 diabetes: A cost-utility analysis based on the EXSCEL trial.
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Liraglutide and weight loss among patients with advanced heart failure and a reduced ejection fraction: insights from the FIGHT trial.
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Liraglutide in Weight Management.
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Liver dysfunction in paediatric obesity: a randomized, controlled trial of metformin.
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Long-term outcomes of analogue insulin compared with NPH for patients with type 2 diabetes mellitus.
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Longitudinal medical resources and costs among type 2 diabetes patients participating in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS).
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Low-density lipoprotein cholesterol treatment and outcomes in patients with type 2 diabetes and established cardiovascular disease: Insights from TECOS.
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Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
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Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
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Management of Preexisting Diabetes in Pregnancy: A Review.
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Management of Type 1 Diabetes With a Very Low-Carbohydrate Diet.
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Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
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Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).
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Management of newly treated diabetes in Medicare beneficiaries with and without heart failure.
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Measures of adherence to oral hypoglycemic agents at the primary care clinic level: the role of risk adjustment.
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Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial.
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Medication oversupply in patients with diabetes.
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Meta-analysis of rare events: an update and sensitivity analysis of cardiovascular events in randomized trials of rosiglitazone.
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Metabolic syndrome: evaluation of pathological and therapeutic outcomes.
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Metformin Use Is Associated with Improved Survival in Patients Undergoing Resection for Pancreatic Cancer.
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Metformin and/or clomiphene do not adversely affect liver or renal function in women with polycystic ovary syndrome.
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Metformin association with lower prostate cancer recurrence in type 2 diabetes: a systematic review and meta-analysis.
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Metformin does not affect risk of biochemical recurrence following radical prostatectomy: results from the SEARCH database.
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Metformin exposure is associated with improved progression-free survival in diabetic patients after resection for early-stage non-small cell lung cancer.
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Metformin for weight loss and metabolic control in overweight outpatients with schizophrenia and schizoaffective disorder.
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Metformin in the treatment of non-alcoholic steatohepatitis: a pilot open label trial.
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Metformin is associated with improved survival in endometrial cancer.
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Metformin prevents tobacco carcinogen--induced lung tumorigenesis.
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Metformin reverses fatty liver disease in obese, leptin-deficient mice.
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Metformin use and risk of prostate cancer: results from the REDUCE study.
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Metformin use in patients hospitalized with COVID-19: lower inflammation, oxidative stress, and thrombotic risk markers and better clinical outcomes.
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Metformin use is associated with better survival of diabetic patients with pancreatic cancer.
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Metformin, Diabetes, and Survival among U.S. Veterans with Colorectal Cancer.
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Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
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Methodology of a reevaluation of cardiovascular outcomes in the RECORD trial: study design and conduct.
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Modeling the Budgetary Impact of Payer Utilization Management Strategies: An Adapted Framework Based on Lessons Learned.
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Modification of postprandial hyperglycemia with insulin lispro improves glucose control in patients with type 2 diabetes.
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Mortality and Macrovascular Risk in Elderly With Hypertension and Diabetes: Effect of Intensive Drug Therapy.
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Multi-ethnic comparisons of diabetes in heart failure with reduced ejection fraction: insights from the HF-ACTION trial and the ASIAN-HF registry.
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N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents.
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Neurological Prognostication After Hypoglycemic Coma: Role of Clinical and EEG Findings.
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Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.
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Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone.
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New combination treatments in the management of diabetes: focus on sitagliptin-metformin.
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New strategies in pancreatic cancer: emerging epidemiologic and therapeutic concepts.
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New therapies for type 2 diabetes based on glucagon-like peptide 1.
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Newer second-line glucose-lowering drugs versus thiazolidinediones on cirrhosis risk among older US adult patients with type 2 diabetes.
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Nonalcoholic fatty liver disease in women.
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Once-Weekly Exenatide and Cardiovascular Outcomes in Type 2 Diabetes.
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One-year comparison of a high-monounsaturated fat diet with a high-carbohydrate diet in type 2 diabetes.
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One-year results from the first US-based enhanced recovery after cardiac surgery (ERAS Cardiac) program.
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One-year sustained glycemic control and weight reduction in type 2 diabetes after addition of liraglutide to metformin followed by insulin detemir according to HbA1c target.
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Opportunities for improving use of evidence-based therapy in patients with type 2 diabetes and cardiovascular disease.
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Opportunities to encourage mail order pharmacy delivery service use for diabetes prescriptions: a qualitative study.
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Optimizing perioperative glycemic control.
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Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries.
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Parents' experiences of managing their child's diabetes using an insulin pump: a qualitative study.
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Patient Preferences for Medications in Managing Type 2 Diabetes Mellitus: A Discrete Choice Experiment.
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Patient Self-Management of Diabetes Care in the Inpatient Setting: Pro.
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Patient-reported outcomes in patients with type 2 diabetes treated with liraglutide or glimepiride, both as add-on to metformin.
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Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: a longitudinal qualitative investigation.
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Performance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial: Heart and Lung Failure-Pediatric Insulin Titration Trial (HALF-PINT).
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Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity.
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Pharmacologic Treatment of Diabetes in Pregnancy.
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Pharmacological and surgical treatments for obesity.
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Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1.
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Physical activity and NIDDM in African-Americans. The Pitt County Study.
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Physical activity as a determinant of fasting and 2-h post-challenge glucose: a prospective cohort analysis of the NAVIGATOR trial.
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Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha.
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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.
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Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.
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Plasma glucose response to recreational diving in novice teenage divers with insulin-requiring diabetes mellitus.
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Poor glycemic control is a strong predictor of postoperative morbidity and mortality in patients undergoing vascular surgery.
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Positive Impact of Continuous-Flow Left Ventricular Assist Device Implantation on Glycemic Control in Patients with Type 2 Diabetes Mellitus and Advanced Chronic Systolic Heart Failure.
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Possible differential benefits of edetate disodium in post-myocardial infarction patients with diabetes treated with different hypoglycemic strategies in the Trial to Assess Chelation Therapy (TACT).
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Postoperative hyperglycemia after 4- vs 8-10-mg dexamethasone for postoperative nausea and vomiting prophylaxis in patients with type II diabetes mellitus: a retrospective database analysis.
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Predicting major adverse limb events in individuals with type 2 diabetes: Insights from the EXSCEL trial.
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Predictors of incident heart failure hospitalizations among patients with impaired glucose tolerance: insight from the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research study.
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Predictors of stroke in patients with impaired glucose tolerance: results from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research trial.
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Prescriber Continuity and Disease Control of Older Adults.
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Prevalence of diabetic peripheral neuropathy and relation to glycemic control therapies at baseline in the BARI 2D cohort.
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Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.
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Progesterone inhibits human infragenicular arterial smooth muscle cell proliferation induced by high glucose and insulin concentrations.
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Prospective relationships between body weight and physical activity: an observational analysis from the NAVIGATOR study.
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Protein kinase-zeta interacts with munc18c: role in GLUT4 trafficking.
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Psychometric Properties of the Four-Item Morisky Green Levine Medication Adherence Scale among Atherosclerosis Risk in Communities (ARIC) Study Participants.
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Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting.
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ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function.
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Randomized nutrition education intervention to improve carbohydrate counting in adolescents with type 1 diabetes study: is more intensive education needed?
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Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring.
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Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial.
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Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease.
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Re-adjudication of the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) with study-level meta-analysis of hospitalization for heart failure from cardiovascular outcomes trials with dipeptidyl peptidase-4 (DPP-4) inhibitors.
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Recombinant glucagon-like peptide-1 (7-36 amide) lowers fasting serum glucose in a broad spectrum of patients with type 2 diabetes.
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Reduced Cost-sharing for Preventive Drugs Preferentially Benefits Low-income Patients With Diabetes in High Deductible Health Plans With Health Savings Accounts.
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Regional, age and sex differences in baseline characteristics of patients enrolled in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS).
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Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin.
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Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy.
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Relation between sulfonylurea therapy, complications, and outcome for elderly patients with acute myocardial infarction.
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Relation of severe coronary artery narrowing to insulin or thiazolidinedione use in patients with type 2 diabetes mellitus (from the Bypass Angioplasty Revascularization Investigation 2 Diabetes Study).
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Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding.
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Relationship between adipose tissue insulin resistance and liver histology in nonalcoholic steatohepatitis: a pioglitazone versus vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis trial follow-up study.
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Reply to Suissa and Ariel: The FULFIL Trial.
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Repositioning metformin for cancer prevention and treatment.
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Response to: 'Pharmacokinetic/pharmacodynamic properties and efficacy/safety of U-500R from randomized clinical studies'.
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Results of a reevaluation of cardiovascular outcomes in the RECORD trial.
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Revisiting NPH Insulin for Type 2 Diabetes: Is a Step Back the Path Forward?
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Rosiglitazone versus placebo for men with prostate carcinoma and a rising serum prostate-specific antigen level after radical prostatectomy and/or radiation therapy.
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SPHK1 Is a Novel Target of Metformin in Ovarian Cancer.
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Safe and Efficacious Use of Automated Bolus Advisors in Individuals Treated With Multiple Daily Insulin Injection (MDI) Therapy: Lessons Learned From the Automated Bolus Advisor Control and Usability Study (ABACUS).
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Safely Converting an Entire Academic Medical Center From Sliding Scale to Basal Bolus Insulin via Implementation of the eGlycemic Management System.
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Secondary Prevention of Cardiovascular Disease in Patients With Type 2 Diabetes Mellitus: International Insights From the TECOS Trial (Trial Evaluating Cardiovascular Outcomes With Sitagliptin).
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Selective upregulated expression of the alpha2-macroglobulin signaling receptor in highly metastatic 1-LN prostate carcinoma cells.
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Self-management practices of Chinese Americans with type 2 diabetes.
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Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets.
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Severe insulin resistance in a patient with type 1 diabetes and stiff-man syndrome treated with insulin lispro.
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Sex differences in management and outcomes of patients with type 2 diabetes and cardiovascular disease: A report from TECOS.
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Sex differences in the complications, care and clinical outcomes of patients with type 2 diabetes in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).
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Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children.
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Simplifying therapy to assure glycemic control and engagement (STAGE) in poorly-controlled diabetes: A pilot study.
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Sitagliptin and risk of fractures in type 2 diabetes: Results from the TECOS trial.
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Slow and Steady Wins the Race: 25 Years Developing the GLP-1 Receptor as an Effective Target for Weight Loss.
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Sodium-Glucose Cotransporter-2 Inhibitors: Impact on Atherosclerosis and Atherosclerotic Cardiovascular Disease Events.
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Sodium-glucose co-transporter-2 inhibitor use and risk of lower-extremity amputation: Evolving questions, evolving answers.
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Standardization of the single-breath diffusing capacity in a multicenter clinical trial.
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Statins are Associated With Increased Biochemical Recurrence After Radical Prostatectomy in Diabetic Men but no Association was Seen in Men also Taking Metformin: Results From the SEARCH Database.
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Sulfonylurea Prescribing Patterns After the Introduction of DPP-4 Inhibitors and GLP-1 Receptor Agonists.
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Surgical Treatment of Diabetes: Making a Case for a Pragmatic Approach.
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Systemic management of diabetic retinopathy.
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Targeted Multiplex Gene Expression Profiling to Measure High-Fat Diet and Metformin Effects on Fetal Gene Expression in a Mouse Model.
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Targeting the Incretin/Glucagon System With Triagonists to Treat Diabetes.
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Technosphere insulin: inhaled prandial insulin.
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Testing a very low-carbohydrate adaption of the Diabetes Prevention Program among adults with prediabetes: study protocol for the Lifestyle Education about prediabetes (LEAP) trial.
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The Clinical Antipsychotic Trials Of Intervention Effectiveness (CATIE) Schizophrenia Trial: clinical comparison of subgroups with and without the metabolic syndrome.
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The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.
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The Pregnancy in Polycystic Ovary Syndrome study: baseline characteristics of the randomized cohort including racial effects.
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The balance of benefit and safety of rosiglitazone: important lessons for our system of drug development and postmarketing assessment.
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The contribution of enteroinsular hormones to the pathogenesis of type 2 diabetes mellitus.
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The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association.
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The effect of chronic twice daily exenatide treatment on β-cell function in new onset type 2 diabetes.
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The effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes.
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The effects of optimal perioperative glucose control on morbidly obese patients undergoing bariatric surgery.
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The emerging role of novel antihyperglycemic agents in the treatment of heart failure and diabetes: A focus on cardiorenal outcomes.
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The incretins and beta-cell health: contrasting glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 as a path to understand islet function in diabetes.
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The pathogenesis of insulin resistance in children: metabolic complications and the roles of diet, exercise and pharmacotherapy in the prevention of type 2 diabetes.
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The potential role and rationale for treatment of heart failure with sodium-glucose co-transporter 2 inhibitors.
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The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells.
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The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs.
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The utilization of video-conference shared medical appointments in rural diabetes care.
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Thiazolidinediones, peripheral oedema and congestive heart failure: what is the evidence?
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Three-year follow-up and event rates in the international REduction of Atherothrombosis for Continued Health Registry.
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Time of Day When Type 1 Diabetes Patients With Eating Disorder Symptoms Most Commonly Restrict Insulin.
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Time-dependent event accumulation in a cardiovascular outcome trial of patients with type 2 diabetes and established atherosclerotic cardiovascular disease.
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Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.
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Towards living guidelines on cardiorenal outcomes in diabetes: A pilot project of the Taskforce of the Guideline Workshop 2020.
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Translating the hemoglobin A1C with more easily understood feedback: a randomized controlled trial.
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Treatment of Type 2 diabetes mellitus in Chongqing of China: unaffordable care for the poor.
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Treatment of nonalcoholic fatty liver disease in children: TONIC trial design.
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Treatment preferences and medication adherence of people with Type 2 diabetes using oral glucose-lowering agents.
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Treatment with incretins does not increase the risk of pancreatic diseases compared to older anti-hyperglycaemic drugs, when added to metformin: real world evidence in people with Type 2 diabetes.
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Trends in glyburide compared with insulin use for gestational diabetes treatment in the United States, 2000-2011.
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Triglycerides: Emerging Targets in Diabetes Care? Review of Moderate Hypertriglyceridemia in Diabetes.
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Two diets with different haemoglobin A1c and antiglycaemic medication effects despite similar weight loss in type 2 diabetes.
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Type 2 Diabetes Mellitus and Heart Failure, A Scientific Statement From the American Heart Association and Heart Failure Society of America.
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Type 2 diabetes, thiazolidinediones: bad to the bone?
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Understanding the type 2 diabetes mellitus and cardiovascular disease risk paradox.
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Unsupervised home use of an overnight closed-loop system over 3-4 weeks: a pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes.
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Update on type 2 diabetes mellitus: understanding changes in the diabetes treatment paradigm.
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Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses.
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Urinary Angiotensinogen Could Be a Prognostic Marker of Renoprotective Effects of Alogliptin in Patients with Type 2 Diabetes.
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Use of Lipid-, Blood Pressure-, and Glucose-Lowering Pharmacotherapy in Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease.
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Use of an automated bolus calculator reduces fear of hypoglycemia and improves confidence in dosage accuracy in patients with type 1 diabetes mellitus treated with multiple daily insulin injections.
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Use of an insulin bolus advisor facilitates earlier and more frequent changes in insulin therapy parameters in suboptimally controlled patients with diabetes treated with multiple daily insulin injection therapy: results of the ABACUS trial.
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Use of an insulin bolus advisor improves glycemic control in multiple daily insulin injection (MDI) therapy patients with suboptimal glycemic control: first results from the ABACUS trial.
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Use of automated bolus advisors may improve adherence to multiple daily insulin injection therapy.
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Using a Budget Impact Model Framework to Evaluate Antidiabetic Formulary Changes and Utilization Management Tools.
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Using a low-carbohydrate diet to treat obesity and type 2 diabetes mellitus.
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Using genetics to enable studies on the prevention of Alzheimer's disease.
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Using insulin to prevent hyperglycemia in surgical patients.
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Utilizing mobile technologies to improve physical activity and medication adherence in patients with heart failure and diabetes mellitus: Rationale and design of the TARGET-HF-DM Trial.
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Validating a Budget Impact Model Using Payer Insight and Claims Data: A Framework and Case Study.
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Vanadyl sulfate inhibits NO production via threonine phosphorylation of eNOS.
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Venous thromboembolism and cardiovascular risk: results from the NAVIGATOR trial.
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Weight change in patients with type 2 diabetes starting basal insulin therapy: correlates and impact on outcomes.
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Wide clinic-level variation in adherence to oral diabetes medications in the VA.
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Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL).
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Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants.
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Keywords of People
-
Alexander, John Hunter Peel,
Professor of Medicine,
Medicine, Cardiology
-
Freemark, Michael Scott,
Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine,
Pediatrics, Endocrinology
-
O'Connor, Christopher Michael,
Adjunct Professor in the Department of Medicine,
Medicine, Clinical Pharmacology
-
Pitt, Geoffrey Stuart,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
-
Yancy Jr., William Samuel,
Professor of Medicine,
Medicine, General Internal Medicine