Hypothermia, Induced
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Subject Areas on Research
- A clinical comparison of mitral valve repair versus valve replacement in ischemic mitral regurgitation.
- A comfortable hypothesis reevaluated. Cerebral metabolic depression and brain protection during ischemia.
- A prospective, multicenter pilot study to evaluate the feasibility and safety of using the CoolGard System and Icy catheter following cardiac arrest.
- A structured educational intervention to improve targeted temperature management utilization after cardiac arrest.
- Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial.
- American Clinical Neurophysiology Society Guideline 5: Minimum Technical Standards for Pediatric Electroencephalography.
- An evidence-based review of the practice of cardiopulmonary bypass in adults: a focus on neurologic injury, glycemic control, hemodilution, and the inflammatory response.
- Analysis of injury in complex organ preservation.
- Anesthetic management of deep hypothermic circulatory arrest for cerebral aneurysm clipping.
- Association Between Therapeutic Hypothermia and Survival After In-Hospital Cardiac Arrest.
- Bispectral analysis during cardiopulmonary bypass: the effect of hypothermia on the hypnotic state.
- Blockade of the extracellular signal-regulated kinase pathway by U0126 attenuates neuronal damage following circulatory arrest.
- Brain injury and protective effects of hypothermia using triphenyltetrazolium chloride in neonatal rat.
- Brain injury following trial of hypothermia for neonatal hypoxic-ischaemic encephalopathy.
- Cardiopulmonary Bypass Strategy for a Cyanotic Child With Hemoglobin SC Disease.
- Cardiopulmonary bypass and the central nervous system: potential for cerebral protection.
- Cardiopulmonary bypass time does not affect cerebral blood flow.
- Case 4--1998. Cardiopulmonary bypass and hypothermic circulatory arrest for basilar artery aneurysm clipping.
- Cerebral blood flow values during cardiopulmonary bypass: relatively absolute or absolutely relative?
- Cerebral physiologic effects of burst suppression doses of propofol during nonpulsatile cardiopulmonary bypass. CNS Subgroup of McSPI.
- Cerebral protection.
- Changes in cerebral and somatic oxygenation during stage 1 palliation of hypoplastic left heart syndrome using continuous regional cerebral perfusion.
- Characterization of Death in Neonatal Encephalopathy in the Hypothermia Era.
- Childhood outcomes after hypothermia for neonatal encephalopathy.
- Clinical predictors of survival in patients treated with therapeutic hypothermia following cardiac arrest.
- Clinical seizures in neonatal hypoxic-ischemic encephalopathy have no independent impact on neurodevelopmental outcome: secondary analyses of data from the neonatal research network hypothermia trial.
- Communication Challenges in Neonatal Encephalopathy.
- Comparing two strategies of cardiopulmonary bypass cooling on jugular venous oxygen saturation in neonates and infants.
- Comparison of myocardial protection with nifedipine and potassium.
- Conduction block after cardioplegic arrest: prevention by augmented atrial hypothermia.
- Contemporary management and outcomes of acute type A aortic dissection: An analysis of the STS adult cardiac surgery database.
- Continuous jugular venous versus nasopharyngeal temperature monitoring during hypothermic cardiopulmonary bypass for cardiac surgery.
- Corrected transposition with severe intracardiac deformities with Wolff-Parkinson-White syndrome in a child. Electrophysiologic investigation and surgical correction.
- Correspondence regarding "Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy".
- Current advances in the use of therapeutic hypothermia.
- Deep hypothermia in infant cardiac surgery.
- Differential age effects of mean arterial pressure and rewarming on cognitive dysfunction after cardiac surgery.
- Discrete cerebral hypothermia in the management of traumatic brain injury: a randomized controlled trial.
- Does moderate hypothermia really carry less bleeding risk than deep hypothermia for circulatory arrest? A propensity-matched comparison in hemiarch replacement.
- Effect of Depth and Duration of Cooling on Death or Disability at Age 18 Months Among Neonates With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
- Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
- Effect of deep hypothermia and circulatory arrest on cerebral blood flow and metabolism.
- Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial.
- Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy: secondary analyses of the NICHD whole-body cooling trial.
- Effect of local hypothermia on early wound repair.
- Effect of mild hypothermia during and after transient in vitro ischemia on metabolic disturbances in hippocampal slices at different stages of development.
- Effect of temperature during cardiopulmonary bypass on gastric mucosal perfusion.
- Effect of temperature on kainic acid-induced seizures.
- Effects of aortopulmonary collaterals on cerebral cooling and cerebral metabolic recovery after circulatory arrest.
- Effects of cold ischemia on reflow patterns in the rat cremaster muscle microcirculation.
- Effects of internal mammary artery dissection on phrenic nerve perfusion and function.
- Effects of moderate versus deep hypothermic circulatory arrest and selective cerebral perfusion on cerebrospinal fluid proteomic profiles in a piglet model of cardiopulmonary bypass.
- Elevated temperature after hypoxic-ischemic encephalopathy: risk factor for adverse outcomes.
- Endothelial dysfunction in cerebral microcirculation during hypothermic cardiopulmonary bypass in newborn lambs.
- Evolution of encephalopathy during whole body hypothermia for neonatal hypoxic-ischemic encephalopathy.
- Feasibility and safety of combined percutaneous coronary intervention and therapeutic hypothermia following cardiac arrest.
- Feasibility and safety of moderate hypothermia after massive hemispheric infarction.
- Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy.
- Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study).
- Feeling the heat.
- Hemodilution during cardiopulmonary bypass increases cerebral infarct volume after middle cerebral artery occlusion in rats.
- Hyperammonemia in the ICU.
- Hypocarbia and adverse outcome in neonatal hypoxic-ischemic encephalopathy.
- Hypothermia and operative mortality during on-pump coronary artery bypass grafting.
- Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation.
- Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain.
- Impact of percutaneous coronary intervention performance reporting on cardiac resuscitation centers: a scientific statement from the American Heart Association.
- Induced hypothermia for neonates with hypoxic-ischemic encephalopathy.
- Induction of hypothermia after intraoperative hypoxic brain insult.
- Integrating neurocritical care approaches into neonatology: should all infants be treated equitably?
- Intermittent perfusion protects the brain during deep hypothermic circulatory arrest.
- Interrater reliability of the bedside shivering assessment scale.
- Interventional strategies associated with improvements in survival for out-of-hospital cardiac arrests in Singapore over 10 years.
- Intestinal mast cells mediate gut injury and systemic inflammation in a rat model of deep hypothermic circulatory arrest.
- Long-term neuroprotection by benzodiazepine full versus partial agonists after transient cerebral ischemia in the gerbil [corrected]
- Low-flow cardiopulmonary bypass produces greater pulmonary dysfunction than circulatory arrest.
- Management of cardiogenic shock.
- Mild hypothermia reduces infarct size resulting from temporary but not permanent focal ischemia in rats.
- Moderate hypothermia induces marked increase in levels and nuclear accumulation of SUMO2/3-conjugated proteins in neurons.
- Modified ultrafiltration improves cerebral metabolic recovery after circulatory arrest.
- Monitoring the brain during cardiac surgery in children.
- Monitoring the jugular-venous oxyhemoglobin saturation as a decision aid for normothermic cardiopulmonary bypass.
- Myocardial function is normal after rapid cooling of the in vivo neonatal heart.
- Neurologic outcome after cardiopulmonary bypass with deep hypothermic circulatory arrest in rats: description of a new model.
- Neurologic outcomes after coronary artery bypass grafting with and without cardiopulmonary bypass.
- No association between intraoperative hypothermia or supplemental protective drug and neurologic outcomes in patients undergoing temporary clipping during cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial.
- Organ protective mechanisms common to extremes of physiology: a window through hibernation biology.
- Outcome of term infants using apgar scores at 10 minutes following hypoxic-ischemic encephalopathy.
- Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy.
- Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy.
- Parent Experience of Neonatal Encephalopathy.
- Perioperative fever and outcome in surgical patients with aneurysmal subarachnoid hemorrhage.
- Perioperative hypothermia (33 degrees C) does not increase the occurrence of cardiovascular events in patients undergoing cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial.
- Perioperative hypothermia: use and therapeutic implications.
- Perioperative temperature and cardiac surgery.
- Pharmacologic protection from ischemic neuronal injury.
- Pharmacological correction of hypothermic P(50) shift does not alter outcome from focal cerebral ischemia in rats.
- Phenobarbital and temperature profile during hypothermia for hypoxic-ischemic encephalopathy.
- Plasma Glycoproteomic Study of Therapeutic Hypothermia Reveals Novel Markers Predicting Neurologic Outcome Post-cardiac Arrest.
- Post-myocardial infarction cardiogenic shock is a systemic illness in need of systemic treatment: is therapeutic hypothermia one possibility?
- Postoperative hyperthermia is associated with cognitive dysfunction after coronary artery bypass graft surgery.
- Predictive performance of a gentamicin population pharmacokinetic model in neonates receiving full-body hypothermia.
- Prospective randomized trial of normothermic versus hypothermic cardiopulmonary bypass on cognitive function after coronary artery bypass graft surgery.
- Randomized clinical trial progress to inform care for out-of-hospital cardiac arrest.
- Recovery of cerebral metabolism and mitochondrial oxidation state is delayed after hypothermic circulatory arrest.
- Renal medullary and urinary oxygen tension during cardiopulmonary bypass in the rat.
- Respiratory controversies in the critical care setting. Conference summary.
- Right ventricular sensitivity to metabolic injury during cardiopulmonary bypass.
- Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement.
- Serum lactates correlate with mortality after operations for complex congenital heart disease.
- Supraventricular conduction abnormalities following cardiac operations. A complication of inadequate atrial preservation.
- Surgical treatment of supraventricular tachyarrhythmias.
- Temperature during coronary artery bypass surgery affects quality of life.
- Temperature profile and outcomes of neonates undergoing whole body hypothermia for neonatal hypoxic-ischemic encephalopathy.
- Temperatures achieved in human and canine neocortex during intraoperative passive or active focal cooling.
- The Use of Whole Body Cooling in the Treatment of Hypoxic-Ischemic Encephalopathy.
- The effect of duration of hypothermic cardioplegia on ventricular function.
- The effect of temperature on cerebral metabolism and blood flow in adults during cardiopulmonary bypass.
- The electrophysiological effects of calcium channel blockade during standard hyperkalemic hypothermic cardioplegic arrest.
- The incidence of unacceptable movement with motor evoked potentials during craniotomy for aneurysm clipping.
- The relation between cerebral metabolic rate and ischemic depolarization. A comparison of the effects of hypothermia, pentobarbital, and isoflurane.
- The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery.
- The thermoresponsiveness of ventromedial hypothalamic (VMH) neurons following repeated scrotal thermal stimulation of rats maintained at normothermic or acutely hypothermic core temperatures.
- Therapeutic Hypothermia for Patients with Out-of-Hospital Cardiac Arrest in North Carolina.
- Therapeutic hypothermia in post-cardiac arrest.
- Transcranial Doppler blood flow velocity versus 133Xe clearance cerebral blood flow during mild hypothermic cardiopulmonary bypass.
- Translational research in acute central nervous system injury: lessons learned and the future.
- Traumatic brain injury and hypothermia.
- Treatment of chemotherapy-induced alopecia.
- Variability in Postarrest Targeted Temperature Management Practice: Implications of the 2015 Guidelines.
- Volatile anesthetic sedation during therapeutic hypothermia after cardiac arrest in the ICU: a journey of a thousand miles begins with a single step.
- Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy.
- Xenon neuroprotection in experimental stroke: interactions with hypothermia and intracerebral hemorrhage.
- [Anatomical correction of transposition of the great arteries in 7 newborn infants]
- pH-stat cooling improves cerebral metabolic recovery after circulatory arrest in a piglet model of aortopulmonary collaterals.
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Keywords of People
- Berger, Miles, Assistant Professor of Anesthesiology, Duke Science & Society
- James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology, Neuroanesthesia
- Milano, Carmelo Alessio, Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery
- Muh, Carrie Rebecca, Adjunct Assistant Professor in the Department of Neurosurgery, Neurosurgery
- Nielsen, Karen Cristina, Associate Professor of Anesthesiology, Anesthesiology, Ambulatory
- Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
- Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology
- Zhang, Zhiquan, Assistant Professor in Anesthesiology, Anesthesiology