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Subject Areas on Research
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A comparative evaluation of nasal and parenteral vaccine adjuvants to elicit systemic and mucosal HIV-1 peptide-specific humoral immune responses in cynomolgus macaques.
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A comparative study of monoclonal gammopathies and immunoglobulin levels in Japanese and United States elderly.
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Activation of human B lymphocytes. XIII. Characterization of multiple populations of naturally occurring immunoregulatory cells of polyclonally induced in vitro human B cell function.
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Agglutination of Naegleria fowleri and Naegleria gruberi by antibodies in human serum.
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Aggregate complexes of HIV-1 induced by multimeric antibodies.
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Alterations in HLA-DP and HLA-DQ antigen frequency in patients with dermatitis herpetiformis.
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Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome.
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Altered lung gene expression in CCSP-null mice suggests immunoregulatory roles for Clara cells.
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An in vitro analogue of immune dysfunction with altered immunoglobulin production in the aged.
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Analysis of autoantibodies to plasminogen in the serum of patients with rheumatoid arthritis.
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Anaphylactic reactions after gamma globulin administration in patients with hypogammaglobulinemia. Detection of IgE antibodies to IgA.
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Anaphylactic reactions to plasma infusions in patients with hypogammaglobulinemia and anti-IgA antibodies.
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Anaphylaxis after administration of gamma globulin for hypogammaglobulinemia.
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Anti-EBV serologic tests for nasopharyngeal carcinoma.
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Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women.
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Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.
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Anticardiolipin antibodies and osteonecrosis of the femoral head.
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Apical and basolateral endocytic pathways of MDCK cells meet in acidic common endosomes distinct from a nearly-neutral apical recycling endosome.
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Application of Epstein-Barr virus (EBV) serology to the diagnosis of North American nasopharyngeal carcinoma.
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Application of Epstein-Barr virus serology to the diagnosis and staging of North American patients with nasopharyngeal carcinoma.
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Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.
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B-cell lymphopenia and hypogammaglobulinemia in thymoma patients.
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Biofilms in the large bowel suggest an apparent function of the human vermiform appendix.
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Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques.
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Brefeldin A rapidly disrupts plasma membrane polarity by blocking polar sorting in common endosomes of MDCK cells.
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Broadly neutralizing antibody specificities detected in the genital tract of HIV-1 infected women.
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CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation.
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CD28 is required for germinal center formation.
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COMPASS identifies T-cell subsets correlated with clinical outcomes.
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Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair in vitro models of synaptic plasticity in rat hippocampus.
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Characterization of circulating and cutaneous IgA immune complexes in patients with dermatitis herpetiformis.
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Characterization of the mucosal immune response to dietary antigens in patients with dermatitis herpetiformis.
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Circulating IgA immune complexes in patients with psoriasis.
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Clinical application of whole-genome sequencing in patients with primary immunodeficiency.
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Clinicopathologic features and outcomes of lymphoplasmacytic lymphoma patients with monoclonal IgG or IgA paraprotein expression.
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Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk.
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Comparison of the intestinal and serum antibody response in patients with dermatitis herpetiformis.
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Concomitant Waldenstrom macroglobulinemia and IgA plasmablastic myeloma in a patient with untreated IgM paraproteinemia: sequential development of biclonal B-cell neoplasms over a 10-year period in a single individual.
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Control of simian/human immunodeficiency virus viremia and disease progression after IL-2-augmented DNA-modified vaccinia virus Ankara nasal vaccination in nonhuman primates.
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Correction of severe combined immunodeficiency by fetal liver cells.
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Correlation of vaccine-elicited systemic and mucosal nonneutralizing antibody activities with reduced acute viremia following intrarectal simian immunodeficiency virus SIVmac251 challenge of rhesus macaques.
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Cost-effectiveness analysis of strategies for diagnosing celiac disease.
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Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques.
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Cutaneous endothelial cell activation in normal skin of patients with dermatitis herpetiformis associated with increased serum levels of IL-8, sE-Selectin, and TNF-alpha.
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Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization.
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DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.
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DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory.
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Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency.
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Definition of distinct compartments in polarized Madin-Darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling.
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Depression of cell-mediated immunity in atopic eczema.
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Dermatitis herpetiformis and the mucosal immune response.
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Dermatitis herpetiformis.
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Dermatitis herpetiformis.
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Dermatitis herpetiformis: the skin and the gut.
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Dermatomyositis associated with IgA deposition.
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Development of multiple monoclonal serum immunoglobulins (multiclonal gammopathy) following both HLA-identical unfractionated and T cell-depleted haploidentical bone marrow transplantation in severe combined immunodeficiency.
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Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel.
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Does chronic Chlamydia pneumoniae infection increase the risk of myocardial injury? Insights from patients with non-ST-elevation acute coronary syndromes.
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Early relapse after autologous hematopoietic cell transplantation remains a poor prognostic factor in multiple myeloma but outcomes have improved over time.
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Effect of bismuth salts on systemic and mucosal immune responses to orally administered cholera toxin.
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Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis.
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Effective induction of simian immunodeficiency virus-specific systemic and mucosal immune responses in primates by vaccination with proviral DNA producing intact but noninfectious virions.
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Elevated IgA concentration in milk produced by mothers delivered of preterm infants.
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Elevated serum secretory immunoglobulin A levels in patients with head and neck carcinoma.
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Enteroviral meningoencephalitis as a complication of X-linked hyper IgM syndrome.
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Enzyme immunoassay for detection of human immunodeficiency virus-specific immunoglobulin A antibodies.
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Evaluation of hyperviscosity in monoclonal gammopathies.
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Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6).
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Fate of four cadaveric donor renal allografts with mesangial IgA deposits.
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Frequency of celiac disease in individuals with Down syndrome in the United States.
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Function of the secretory immune system in bronchogenic carcinoma. Immunoglobulin A levels in respiratory secretions.
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GM-CSF DNA: an adjuvant for higher avidity IgG, rectal IgA, and increased protection against the acute phase of a SHIV-89.6P challenge by a DNA/MVA immunodeficiency virus vaccine.
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Generation of human IgG, IgA, and IgM anti-melanoma monoclonal antibodies utilizing lymphocytes of an actively immunized melanoma patient.
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Graft versus host disease-related secretory immunoglobulin A deficiency in bone marrow transplant recipients. Findings in labial saliva.
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HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life.
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HIV-1 specific IgA detected in vaginal secretions of HIV uninfected women participating in a microbicide trial in Southern Africa are primarily directed toward gp120 and gp140 specificities.
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HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge.
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HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.
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HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine.
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HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.
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HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition.
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Heavy-chain receptor editing unbound.
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Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues.
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Heterogeneity of lymphocyte subpopulations in severe combined immunodeficiency. Evidence against a stem cell defect.
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Human nasopharyngeal-associated lymphoreticular tissues. Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils.
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Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses.
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IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens.
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Identification of selective immunoglobulin a deficiency by renal biopsy.
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Idiopathic monoclonal (IgA) gammopathy in a dog.
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IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis.
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IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model.
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IgA antibodies against reticulin and endomysium in the serum and gastrointestinal secretions of patients with dermatitis herpetiformis.
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IgA immune complexes in patients with dermatitis herpetiformis occur in the absence of IgA rheumatoid factor.
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IgA in saliva of breast-fed and bottle-fed infants.
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IgA-binding structures in dermatitis herpetiformis skin are independent of elastic-microfibrillar bundles.
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IgA-containing circulating immune complexes in dermatitis herpetiformis, Henoch-Schönlein purpura, systemic lupus erythematosus and other diseases.
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IgA-containing circulating immune complexes in gluten-sensitive enteropathy.
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IgA-containing circulating immune complexes in patients with igA nephropathy.
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IgA-containing immune complexes in patients with psoriatic arthritis.
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Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses.
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Immune-correlates analysis of an HIV-1 vaccine efficacy trial.
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Immunization with Salmonella enterica serovar Typhimurium-derived outer membrane vesicles delivering the pneumococcal protein PspA confers protection against challenge with Streptococcus pneumoniae.
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Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients.
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Immunoblot analysis of anti-Ureaplasma urealyticum antibody in pregnant women and newborn infants.
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Immunofluorescent studies on the trabecular meshwork in open-angle glaucoma.
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Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes.
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Immunoglobulin localization in benign and malignant lesions of the human mammary gland.
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Immunoglobulin localization in the normal human mammary gland: variation with the menstrual cycle.
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Immunoglobulin prophylaxis in patients with antibody deficiency syndromes and anti-IgA antibodies.
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Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques.
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In-vitro inhibitory effect of maternal breastmilk components on rotavirus vaccine replication and association with infant seroconversion to live oral rotavirus vaccine.
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Incompatible bone-marrow transplantation in lymphopenic immunologic deficiency. Circumvention of fatal graft-versus-host disease by immunologic enhancement.
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Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses.
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Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine.
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Kernel-based logistic regression model for protein sequence without vectorialization.
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Lessons learned from HIV-1 vaccine trials: new priorities and directions.
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Leukocytoclastic vasculitis as the presenting feature of dermatitis herpetiformis.
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Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeys.
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Long term use of intravenous immune globulin in patients with primary immunodeficiency diseases: inadequacy of current dosage practices and approaches to the problem.
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Longitudinal changes in serum immunoglobulin levels in older humans.
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Management of dermatitis herpetiformis.
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Maternal Humoral Immune Responses Do Not Predict Postnatal HIV-1 Transmission Risk in Antiretroviral-Treated Mothers from the IMPAACT PROMISE Study.
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Maternal antibody interference contributes to reduced rotavirus vaccine efficacy in developing countries.
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Maternal cholera immunisation and scecretory IgA in breast milk.
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Maternal cytomegalovirus-specific immune responses and symptomatic postnatal cytomegalovirus transmission in very low-birth-weight preterm infants.
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Membrane receptors and in vitro responsiveness of lymphocytes in human immunodeficiency.
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Memory B cell and other immune responses in children receiving two doses of an oral killed cholera vaccine compared to responses following natural cholera infection in Bangladesh.
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Microbial biofilms in the gut: visualization by electron microscopy and by acridine orange staining.
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Mucosal and systemic adjuvant activity of alphavirus replicon particles.
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Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.
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Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates.
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Neo-epitope tissue transglutaminase autoantibodies as a biomarker of the gluten sensitive skin disease--dermatitis herpetiformis.
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Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection.
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Neutrophil CD11b, L-selectin and Fc IgA receptors in patients with dermatitis herpetiformis.
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No prognostic significance of chronic infection with Chlamydia pneumoniae in acute coronary syndromes: insights from the Global Utilization of Strategies to Open Occluded Arteries IV Acute Coronary Syndromes trial.
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Non-specific and specific immunotherapy in patients with melanoma.
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Noninvasive measurement of mucosal immunity in a free-ranging baboon population.
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Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node.
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Novel intranasal pertussis vaccine based on bacterium-like particles as a mucosal adjuvant.
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Ocular cicatricial pemphigoid with granular IgA and complement deposition.
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Optimization of mucosal responses after intramuscular immunization with integrase defective lentiviral vector.
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Oral immunogenicity of the plant proteinase bromelain.
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Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection.
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Passively transmitted gp41 antibodies in babies born from HIV-1 subtype C-seropositive women: correlation between fine specificity and protection.
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Pathophysiology of dermatitis herpetiformis: a model for cutaneous manifestations of gastrointestinal inflammation.
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Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial.
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Plasma therapy in immunodeficiency diseases.
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Plasma therapy in immunodeficiency diseases.
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Platelet factor 4/heparin antibody (IgG/M/A) in healthy subjects: a literature analysis of commercial immunoassay results.
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Preexisting vaccinia virus immunity decreases SIV-specific cellular immunity but does not diminish humoral immunity and efficacy of a DNA/MVA vaccine.
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Present status of pyoderma gangrenosum. Review of 21 cases.
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Prevalence of antibodies to rotavirus in different age-groups of infants in Bochum, West Germany.
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Prevalence of celiac disease and gluten sensitivity in the United States clinical antipsychotic trials of intervention effectiveness study population.
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Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.
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Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells.
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Randomized trial comparing the safety and antibody responses to live attenuated versus inactivated influenza vaccine when administered to breastfeeding women.
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Randomized, Double-Blind Evaluation of Late Boost Strategies for HIV-Uninfected Vaccine Recipients in the RV144 HIV Vaccine Efficacy Trial.
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Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1.
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Response of the secretory immune system to bronchogenic carcinoma of the lung.
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RhoB-dependent modulation of postendocytic traffic in polarized Madin-Darby canine kidney cells.
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SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses.
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Salt-split human skin substrate for the immunofluorescent screening of serum from patients with cicatricial pemphigoid and a new method of immunoprecipitation with IgA antibodies.
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Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women.
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Secretory immune response in patients with oropharyngeal carcinoma.
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Seroconversion patterns to four human rotavirus serotypes in hospitalized infants with acute rotavirus gastroenteritis.
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Serum IL-8 in patients with dermatitis herpetiformis is produced in response to dietary gluten.
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Serum IgD and IgE concentrations in immunodeficiency diseases.
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Serum immunogbulin cocentrations during normal pregnancy.
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Severe combined immunodeficiency with leukopenia (reticular dysgenesis) in siblings: immunologic and histopathologic findings.
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Soluble interleukin-2 receptor levels in patients with dermatitis herpetiformis.
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Streptokinase promotes development of dipeptidyl peptidase IV (CD26) autoantibodies after fibrinolytic therapy in myocardial infarction patients.
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Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses.
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The 120-kDa soluble ectodomain of type XVII collagen is recognized by autoantibodies in patients with pemphigoid and linear IgA dermatosis.
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The common mucosal immune system: from basic principles to enteric vaccines with relevance for the female reproductive tract.
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The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines.
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The differentiated form of nasopharyngeal carcinoma contains Epstein-Barr virus DNA.
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The nephrotic syndrome in congenital syphilis: an immunopathy.
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The pathogenesis of dermatitis herpetiformis.
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The pathogenesis of dermatitis herpetiformis: recent advances.
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Transient hypogammaglobulinemia of infancy: review of the literature, clinical and immunologic features of 11 new cases, and long-term follow-up.
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Transplantation outcomes for severe combined immunodeficiency, 2000-2009.
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Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.
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Value of day 100 screening studies for predicting the development of chronic graft-versus-host disease after allogeneic bone marrow transplantation.
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Vancomycin-associated linear IgA dermatosis. A report of three cases.
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[IgA pemphigus. Successful treatment with mycophenolate mofetil].
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Keywords of People
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Buckley, Rebecca Hatcher,
James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine,
Immunology
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Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
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Weinhold, Kent James,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, in the School of Medicine,
Immunology