Immunoglobulin E

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  Subject Areas on Research

  • A Collective Review on Hazards of Powder on Surgical and Examination Gloves. 
  • A cell culture system that enhances mononuclear cell IgE synthesis induced by recombinant human interleukin-4. 
  • A mast cell-thermoregulatory neuron circuit axis regulates hypothermia in anaphylaxis. 
  • A retrospective analysis of cross-reacting cetuximab IgE antibody and its association with severe infusion reactions. 
  • Abnormalities in the regulation of human IgE synthesis. 
  • Abnormalities in the regulation of human IgE synthesis. 
  • Abnormalities of leukotaxis in atopic dermatitis. 
  • Acrodermatitis enteropathica-like eruption and food allergy. 
  • Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic asthma. 
  • Allergic lung responses are increased in prostaglandin H synthase-deficient mice. 
  • Allergic response to medical products in patients with alpha-gal syndrome. 
  • Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. 
  • An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response. 
  • An individually, modified approach to desensitize infants and young children with Pompe disease, and significant reactions to alglucosidase alfa infusions. 
  • Anaphylactic reactions after gamma globulin administration in patients with hypogammaglobulinemia. Detection of IgE antibodies to IgA. 
  • Anaphylaxis after administration of gamma globulin for hypogammaglobulinemia. 
  • Anaphylaxis to meperidine. 
  • Antibody formation after drug administration during cardiac surgery: parameters for aprotinin use. 
  • Antibody responses to protein, polysaccharide, and phi X174 antigens in the hyperimmunoglobulinemia E (hyper-IgE) syndrome. 
  • Autoimmune Theories of Chronic Spontaneous Urticaria. 
  • Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry. 
  • Beta-arrestin-2 regulates the development of allergic asthma. 
  • Blocking CCR7 at the ocular surface impairs the pathogenic contribution of dendritic cells in allergic conjunctivitis. 
  • Body mass index-percentile and diagnostic accuracy of childhood asthma. 
  • Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. 
  • Chronic aspiration shifts the immune response from Th1 to Th2 in a murine model of asthma. 
  • Clinical and immunologic features of selective IgA deficiency. 
  • Clinical efficacy and immune regulation with peanut oral immunotherapy. 
  • Common "allergic' skin diseases. 
  • Comparison of pooled fresh frozen serum to proficiency testing material in College of American Pathologists surveys: cortisol and immunoglobulin E. 
  • Depression of cell-mediated immunity in atopic eczema. 
  • Determinants of exhaled nitric oxide levels in healthy, nonsmoking African American adults. 
  • Diagnosis and treatment of anaphylactic/anaphylactoid reactions. 
  • Effect of bismuth salts on systemic and mucosal immune responses to orally administered cholera toxin. 
  • Effects of protamine on histamine release from human lung. 
  • Elevated IgE and atopy in patients treated for early-onset ADA-SCID. 
  • Emerging therapeutics for ocular surface disease. 
  • Eosinophils Mediate Tissue Injury in the Autoimmune Skin Disease Bullous Pemphigoid. 
  • Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis. 
  • Establishment of experimental eosinophilic vasculitis by IgE-mediated cutaneous reverse passive arthus reaction. 
  • Extreme hyperimmunoglobulinemia E and undue susceptibility to infection. 
  • FOXP3 expression following bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning. 
  • Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE. 
  • Food allergy in a patient with adenosine deaminase deficiency undergoing enzyme replacement with polyethylene glycol-modified adenosine deaminase. 
  • Galactose-α-1,3-galactose and delayed anaphylaxis, angioedema, and urticaria in children. 
  • Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells. 
  • Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. 
  • Harboring of particulate allergens within secretory compartments by mast cells following IgE/FcepsilonRI-lipid raft-mediated phagocytosis. 
  • Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy. 
  • Human IgE biosynthesis in vitro: studies with atopic and normal blood mononuclear cells and subpopulations. 
  • Human IgE synthesis in vitro: a reassessment. 
  • Hyper IgM syndrome associated with defective CD40-mediated B cell activation. 
  • Hyperimmunoglobulinemia E syndrome: radiographic observations. 
  • IgE Fc receptor positive T and B lymphocytes in patients with the hyper IgE syndrome. 
  • IgE Fc receptor positive T, B and NK cells in patients with the hyper-IgE syndrome. 
  • IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era. 
  • Immunodeficiency. 
  • Immunology in the Clinic Review Series; focus on allergies: immunotherapy for food allergy. 
  • In Vitro and In Vivo IgE-/Antigen-Mediated Mast Cell Activation. 
  • In vitro studies of IgE synthesis by human blood mononuclear cells. 
  • Increased peanut-specific IgA levels in saliva correlate with food challenge outcomes after peanut sublingual immunotherapy. 
  • Intranasal immunization is superior to vaginal, gastric, or rectal immunization for the induction of systemic and mucosal anti-HIV antibody responses. 
  • Involvement of corneal lymphangiogenesis in a mouse model of allergic eye disease. 
  • L-Selectin is required for the development of airway hyperresponsiveness but not airway inflammation in a murine model of asthma. 
  • L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity. 
  • Laboratory animal allergy: an update. 
  • Links between anxiety and allergies: psychobiological reality or possible methodological bias? 
  • Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID). 
  • Mast cell desensitization inhibits calcium flux and aberrantly remodels actin. 
  • Mast cell regulation of inflammation and gene expression during antigen-induced bladder inflammation in mice. 
  • Mechanism of pokeweed mitogen inhibition of rhIL-4-induced human IgE synthesis. 
  • Molecular editing of cellular responses by the high-affinity receptor for IgE. 
  • Mononuclear cells from patients with the hyper-IgE syndrome produce little IgE when they are stimulated with recombinant human interleukin-4. 
  • Multicenter clinical trials on a novel polyherbal formulation in allergic rhinitis. 
  • Neonatal Job's syndrome featuring a vesicular eruption. 
  • New roles for mast cells in pathogen defense and allergic disease. 
  • Nitric oxide production and mononuclear cell nitric oxide synthase activity in malaria-tolerant Papuan adults. 
  • Nitric oxide production and nitric oxide synthase activity in malaria-exposed Papua New Guinean children and adults show longitudinal stability and no association with parasitemia. 
  • Obesity's effect on asthma extends to diagnostic criteria. 
  • Ocular allergy modulation to hi-dose antigen sensitization is a Treg-dependent process. 
  • Particulate allergens potentiate allergic asthma in mice through sustained IgE-mediated mast cell activation. 
  • Penicillin allergy: A practical guide for clinicians. 
  • Production of TNF-alpha by murine bone marrow derived mast cells activated by the bacterial fimbrial protein, FimH. 
  • Receptor signaling in immune cell development and function. 
  • Recombinant human IL-4 induces IgE and IgG synthesis by normal and atopic donor mononuclear cells. Similar dose response, time course, requirement for T cells, and effect of pokeweed mitogen. 
  • Reduced allergy and immunoglobulin E among adults with intracranial meningioma compared to controls. 
  • Regulation of IgE synthesis: introduction. 
  • Regulation of mast cell survival and function by tuberous sclerosis complex 1. 
  • Respiratory symptoms among crab processing workers in Alaska: epidemiological and environmental assessment. 
  • Role of JAK3 in CD40-mediated signaling. 
  • Safety of a peanut oral immunotherapy protocol in children with peanut allergy. 
  • Safety of open food challenges in the office setting. 
  • Serum IgD and IgE concentrations in immunodeficiency diseases. 
  • Serum IgD concentrations in normal infants, children, and adults and in patients with elevated IgE. 
  • Severe combined immunodeficiency with natural killer-cell predominance: abrogation of graft-versus-host disease and immunologic reconstitution with HLA-identical bone marrow cells. 
  • Structure of the major peanut allergen Ara h 1 may protect IgE-binding epitopes from degradation. 
  • Sugammadex hypersensitivity and underlying mechanisms: a randomised study of healthy non-anaesthetised volunteers. 
  • Surfactant protein D decreases pollen-induced IgE-dependent mast cell degranulation. 
  • Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. 
  • The clinical and environmental determinants of airway transcriptional profiles in allergic asthma. 
  • The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity. 
  • The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace. 
  • The mast cell activator compound 48/80 is safe and effective when used as an adjuvant for intradermal immunization with Bacillus anthracis protective antigen. 
  • The relation of stress and family environment to atopic dermatitis symptoms in children. 
  • The relationship between symptoms and IgG and IgE antibodies in an office environment. 
  • Type B CpG oligodeoxynucleotides induce Th1 responses to peanut antigens: modulation of sensitization and utility in a truncated immunotherapy regimen in mice. 
  • Using the galactose-α-1,3-galactose enzyme-linked immunosorbent assay to predict anaphylaxis in response to cetuximab. 
  • Variability of IgE protein measurement in cell-culture supernatants: results from a multicenter collaborative study. 
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  Keywords of People

  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor Emeritus of Pediatrics, in the School of Medicine, Pediatrics, Allergy and Immunology
  • Zhong, Xiaoping, Professor of Pediatrics, Integrative Immunobiology