Immunologic Factors

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  Subject Areas on Research

  • A blinded, randomized, multicenter study of an intravenous Staphylococcus aureus immune globulin. 
  • A case of atypical Bartonella henselae infection in a patient with methimazole-induced agranulocytosis. 
  • A review of chemotherapy trials for malignant mesothelioma. 
  • A systematic review of morphea treatments and therapeutic algorithm. 
  • A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation. 
  • ALSUntangled No. 16: cannabis. 
  • Acute graft-versus-host disease: are we close to bringing the bench to the bedside? 
  • Anti-DNA antibodies--quintessential biomarkers of SLE. 
  • Antiviral antibodies are necessary for control of simian immunodeficiency virus replication. 
  • Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. 
  • Association between high-dose erythropoiesis-stimulating agents, inflammatory biomarkers, and soluble erythropoietin receptors. 
  • Association of serum B-cell activating factor level and proportion of memory and transitional B cells with clinical response after rituximab treatment of bullous pemphigoid patients. 
  • Autoimmune hepatitis in a child with chronic hepatitis B virus infection. 
  • B cell-directed therapies for autoimmune disease and correlates of disease response and relapse. 
  • Biologics in organ transplantation. 
  • Biologics in relapsing polychondritis: a literature review. 
  • Biology and therapy with biologic agents in gynecologic cancer. 
  • CD19: a promising B cell target for rheumatoid arthritis. 
  • CD83: a regulatory molecule of the immune system with great potential for therapeutic application. 
  • Cardiogenic shock complicates successful treatment of refractory thrombotic thrombocytopenia purpura with rituximab. 
  • Certolizumab pegol plus MTX administered every 4 weeks is effective in patients with RA who are partial responders to MTX. 
  • Characterization of implantable biosensor membrane biofouling. 
  • Cognitive functioning in cancer patients: effect of previous treatment. 
  • Comèl-Netherton syndrome defined as primary immunodeficiency. 
  • Concerning the mechanism of pexelizumab's benefit in acute myocardial infarction. 
  • Controversies in the Management of Isolated Congenital Atrioventricular Block. 
  • Coronary artery thickening with mucosal lesions in Henoch-Schönlein purpura. 
  • Cost-effectiveness considerations in the treatment of essential thrombocythemia. 
  • Differential effects of donor-specific alloantibody. 
  • Diffuse glomerulonephritis induced in rabbits by small intravenous injections of horse serum. 
  • Does IVIg administration yield improved immune function in very premature neonates? 
  • Effect of B-cell depletion on viral replication and clinical outcome of simian immunodeficiency virus infection in a natural host. 
  • Effect of antipyretic analgesics on immune responses to vaccination. 
  • Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study. 
  • Effect of modulating macrophage phenotype on peripheral nerve repair. 
  • Effect of pexelizumab on mortality in patients with acute myocardial infarction or undergoing coronary artery bypass surgery: a systematic overview. 
  • Effects of granulocyte-macrophage colony stimulating factor produced in Chinese hamster ovary cells (regramostim), Escherichia coli (molgramostim) and yeast (sargramostim) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. 
  • Efficacy of remission-induction regimens for ANCA-associated vasculitis. 
  • Etanercept (enbrel)-associated inflammatory eye disease: case report and review of the literature. 
  • Evaluation of Kawasaki disease risk-scoring systems for intravenous immunoglobulin resistance. 
  • Fibroblastic rheumatism: a report of 4 cases with potential therapeutic implications. 
  • Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. 
  • HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response. 
  • Hepatitis C virus-related cryoglobulinemic vasculitis: emerging trends in therapy. 
  • High Blood Pressure Increases Risk of Death Among Human Immunodeficiency Virus Seropositive Individuals in Kenya 
  • Host-Directed Therapies for Tuberculosis. 
  • ICON: the early diagnosis of congenital immunodeficiencies. 
  • IFN-free therapy is associated with restoration of type I IFN response in HIV-1 patients with acute HCV infection who achieve SVR. 
  • Immune modulatory oligonucleotides in prevention of nasal allergen-induced Eustachian tube dysfunction in rats. 
  • Immune modulatory oligonucleotides in the prevention and treatment of OVA-induced eustachian tube dysfunction in rats. 
  • Immunochemotherapy and autologous stem-cell transplantation for untreated patients with mantle-cell lymphoma: CALGB 59909. 
  • Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD. 
  • Immunomodulator effect of picroliv and its potential in treatment against resistant Plasmodium yoelii (MDR) infection in mice. 
  • Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma. 
  • Immunotherapeutic agents for the management of BCG refractory non-muscle invasive bladder cancer. 
  • Immunotherapy and monoclonal antibody therapies. 
  • Immunotherapy for refractory pulmonary infection after adult cardiac surgery: immune dysregulation syndrome. 
  • Immunotherapy in neonatal sepsis: advances in treatment and prophylaxis. 
  • Immunotherapy in the treatment of food allergy: focus on oral tolerance. 
  • Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting. 
  • Intravenous immunoglobulin therapy in intractable childhood epilepsy: open-label study and review of the literature. 
  • Investigational therapies for non-muscle invasive bladder cancer. 
  • Lenalidomide enhances the function of chimeric antigen receptor T cells against the epidermal growth factor receptor variant III by enhancing immune synapses. 
  • Lenalidomide for refractory cutaneous manifestations of pediatric systemic lupus erythematosus. 
  • Lower concentrations of methyl-β-cyclodextrin combined with interleukin-2 can preferentially induce activation and proliferation of natural killer cells in human peripheral blood. 
  • Management of immune dysfunction after adult cardiac surgery. 
  • Mechanism of the anti-tumour effect of biochemotherapy in melanoma: preliminary results. 
  • Myelodysplastic syndromes. 
  • Myelodysplastic syndromes: clinical practice guidelines in oncology. 
  • NMR studies of an immunomodulatory benzodiazepine binding to its molecular target on the mitochondrial F(1)F(0)-ATPase. 
  • Neoadjuvant use of ipilimumab in locally advanced melanoma. 
  • New insights into Chlamydia intracellular survival mechanisms. 
  • Non-erythroid effects of erythropoietin. 
  • Novel chemotherapies in development for management of castration-resistant prostate cancer. 
  • Novel immunotherapeutic strategies in development for renal cell carcinoma. 
  • Pattern and predictors of the initiation of biologic agents for the treatment of rheumatoid arthritis in the United States: an analysis using a large observational data bank. 
  • Pharmacotherapy of severe asthma. 
  • Point-of-care washing of allogeneic red blood cells for the prevention of transfusion-related respiratory complications (WAR-PRC): a protocol for a multicenter randomised clinical trial in patients undergoing cardiac surgery. 
  • Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420. 
  • Predictors of clinical improvement in rituximab-treated refractory adult and juvenile dermatomyositis and adult polymyositis. 
  • Prescription Treatment Options. 
  • Proceedings from the American College of Rheumatology Reproductive Health Summit: the management of fertility, pregnancy, and lactation in women with autoimmune and systemic inflammatory diseases. 
  • Prolonged B-cell depletion in MuSK myasthenia gravis following rituximab treatment. 
  • Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review. 
  • Prospects of immune checkpoint modulators in the treatment of glioblastoma. 
  • Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease. 
  • Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung. 
  • Recombinant interferon-alpha2b added to oral cyclophosphamide either as induction or maintenance in treatment-naive follicular lymphoma: final analysis of CALGB 8691. 
  • Regression of atherosclerosis with therapeutic antibodies pipe cleaner or pipe dream? 
  • Regulatory B cells as inhibitors of immune responses and inflammation. 
  • Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review. 
  • Rituximab therapy for primary Sjögren's syndrome: an open-label clinical trial and mechanistic analysis. 
  • Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement. 
  • Rituximab-associated progressive multifocal leukoencephalopathy after lung transplantation. 
  • Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial. 
  • Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. 
  • Scavenging nucleic acid debris to combat autoimmunity and infectious disease. 
  • Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis. 
  • Specificity and sensitivity of glucocorticoid signaling in health and disease. 
  • Stromal gene signatures in large-B-cell lymphomas. 
  • Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial. 
  • Subcutaneous interferon alfa for the treatment of cutaneous pseudolymphoma. 
  • Successful management of refractory pediatric-onset complex aphthosis with lenalidomide. 
  • Successful treatment of refractory childhood pemphgus vulgaris with anti-CD20 monoclonal antibody (rituximab). 
  • Sweet host revenge: Galectins and GBPs join forces at broken membranes. 
  • Sézary syndrome: immunopathogenesis, literature review of therapeutic options, and recommendations for therapy by the United States Cutaneous Lymphoma Consortium (USCLC). 
  • The Pharmacogenomic Association of Fcγ Receptors and Cytochrome P450 Enzymes With Response to Rituximab or Cyclophosphamide Treatment in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. 
  • The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide. 
  • The clinical relevance of alloantibody in liver transplantation. 
  • The genome of the sea urchin Strongylocentrotus purpuratus. 
  • The n-hexane and chloroform fractions of Piper betle L. trigger different arms of immune responses in BALB/c mice and exhibit antifilarial activity against human lymphatic filarid Brugia malayi. 
  • The role of microparticles in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus. 
  • Tolerability of a new 10% liquid immunoglobulin for intravenous use, Privigen, at different infusion rates. 
  • Translational Research Working Group developmental pathway for immune response modifiers. 
  • Unusual clinical and immunologic manifestations of transplacentally acquired maternal T cells in severe combined immunodeficiency. 
  • Use of tumor necrosis factor inhibitors in uveitis. 
  • Vincristine therapy for severe platelet alloimmunization. 
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  Keywords of People

  • Allen, Nancy Bates, Professor of Medicine, Medicine, Rheumatology and Immunology
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Cohen-Wolkowiez, Michael, Professor of Pediatrics, Pediatrics, Infectious Diseases
  • Wray, Gregory Allan, Professor of Biology, Information Initiative at Duke