Immunologic Factors

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  Subject Areas on Research

  • A blinded, randomized, multicenter study of an intravenous Staphylococcus aureus immune globulin. 
  • A novel model for IFN-γ-mediated autoinflammatory syndromes. 
  • A review of chemotherapy trials for malignant mesothelioma. 
  • A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation. 
  • Acute graft-versus-host disease: are we close to bringing the bench to the bedside? 
  • Anti-DNA antibodies--quintessential biomarkers of SLE. 
  • Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. 
  • Association between high-dose erythropoiesis-stimulating agents, inflammatory biomarkers, and soluble erythropoietin receptors. 
  • Association of serum B-cell activating factor level and proportion of memory and transitional B cells with clinical response after rituximab treatment of bullous pemphigoid patients. 
  • Autoimmune hepatitis in a child with chronic hepatitis B virus infection. 
  • B cell-directed therapies for autoimmune disease and correlates of disease response and relapse. 
  • Biologics in organ transplantation. 
  • Biology and therapy with biologic agents in gynecologic cancer. 
  • CD19: a promising B cell target for rheumatoid arthritis. 
  • CD83: a regulatory molecule of the immune system with great potential for therapeutic application. 
  • Cardiogenic shock complicates successful treatment of refractory thrombotic thrombocytopenia purpura with rituximab. 
  • Certolizumab pegol plus MTX administered every 4 weeks is effective in patients with RA who are partial responders to MTX. 
  • Characterization of implantable biosensor membrane biofouling. 
  • Cognitive functioning in cancer patients: effect of previous treatment. 
  • Combined plasmapheresis and intravenous immune globulin for the treatment of severe maternal red cell alloimmunization. 
  • Comèl-Netherton syndrome defined as primary immunodeficiency. 
  • Controversies in the Management of Isolated Congenital Atrioventricular Block. 
  • Coronary artery thickening with mucosal lesions in Henoch-Schönlein purpura. 
  • Cost-effectiveness considerations in the treatment of essential thrombocythemia. 
  • Diffuse glomerulonephritis induced in rabbits by small intravenous injections of horse serum. 
  • Does IVIg administration yield improved immune function in very premature neonates? 
  • Effect of modulating macrophage phenotype on peripheral nerve repair. 
  • Effect of pexelizumab on mortality in patients with acute myocardial infarction or undergoing coronary artery bypass surgery: a systematic overview. 
  • Effects of granulocyte-macrophage colony stimulating factor produced in Chinese hamster ovary cells (regramostim), Escherichia coli (molgramostim) and yeast (sargramostim) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. 
  • Efficacy of remission-induction regimens for ANCA-associated vasculitis. 
  • Fibroblastic rheumatism: a report of 4 cases with potential therapeutic implications. 
  • HIV vaccines: where we are and where we are going. 
  • Hepatitis C virus-related cryoglobulinemic vasculitis: emerging trends in therapy. 
  • High Blood Pressure Increases Risk of Death Among Human Immunodeficiency Virus Seropositive Individuals in Kenya 
  • Host-Directed Therapies for Tuberculosis. 
  • ICON: the early diagnosis of congenital immunodeficiencies. 
  • Immune modulatory oligonucleotides in prevention of nasal allergen-induced Eustachian tube dysfunction in rats. 
  • Immune modulatory oligonucleotides in the prevention and treatment of OVA-induced eustachian tube dysfunction in rats. 
  • Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD. 
  • Immunotherapy for refractory pulmonary infection after adult cardiac surgery: immune dysregulation syndrome. 
  • Immunotherapy in neonatal sepsis: advances in treatment and prophylaxis. 
  • Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting. 
  • Intravenous immunoglobulin therapy in intractable childhood epilepsy: open-label study and review of the literature. 
  • Management of immune dysfunction after adult cardiac surgery. 
  • Mechanism of the anti-tumour effect of biochemotherapy in melanoma: preliminary results. 
  • Myelodysplastic syndromes: clinical practice guidelines in oncology. 
  • NMR studies of an immunomodulatory benzodiazepine binding to its molecular target on the mitochondrial F(1)F(0)-ATPase. 
  • Neoadjuvant use of ipilimumab in locally advanced melanoma. 
  • New insights into Chlamydia intracellular survival mechanisms. 
  • Non-erythroid effects of erythropoietin. 
  • Novel chemotherapies in development for management of castration-resistant prostate cancer. 
  • Novel immunotherapeutic strategies in development for renal cell carcinoma. 
  • Pattern and predictors of the initiation of biologic agents for the treatment of rheumatoid arthritis in the United States: an analysis using a large observational data bank. 
  • Pharmacotherapy of severe asthma. 
  • Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420. 
  • Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis. 
  • Predictors of clinical improvement in rituximab-treated refractory adult and juvenile dermatomyositis and adult polymyositis. 
  • Proceedings from the American College of Rheumatology Reproductive Health Summit: the management of fertility, pregnancy, and lactation in women with autoimmune and systemic inflammatory diseases. 
  • Prolonged B-cell depletion in MuSK myasthenia gravis following rituximab treatment. 
  • Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review. 
  • Prospects of immune checkpoint modulators in the treatment of glioblastoma. 
  • Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease. 
  • Recombinant interferon-alpha2b added to oral cyclophosphamide either as induction or maintenance in treatment-naive follicular lymphoma: final analysis of CALGB 8691. 
  • Regression of atherosclerosis with therapeutic antibodies pipe cleaner or pipe dream? 
  • Regulatory B cells as inhibitors of immune responses and inflammation. 
  • Response to steroids predicts response to rituximab in pediatric chronic immune thrombocytopenia. 
  • Rituximab therapy for primary Sjögren's syndrome: an open-label clinical trial and mechanistic analysis. 
  • Rituximab versus cyclophosphamide for ANCA-associated vasculitis with renal involvement. 
  • Rituximab-associated progressive multifocal leukoencephalopathy after lung transplantation. 
  • Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial. 
  • Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. 
  • Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. 
  • Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis. 
  • Stromal gene signatures in large-B-cell lymphomas. 
  • Subcutaneous interferon alfa for the treatment of cutaneous pseudolymphoma. 
  • Successful management of refractory pediatric-onset complex aphthosis with lenalidomide. 
  • Successful treatment of refractory childhood pemphgus vulgaris with anti-CD20 monoclonal antibody (rituximab). 
  • Sézary syndrome: immunopathogenesis, literature review of therapeutic options, and recommendations for therapy by the United States Cutaneous Lymphoma Consortium (USCLC). 
  • The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide. 
  • The clinical relevance of alloantibody in liver transplantation. 
  • The genome of the sea urchin Strongylocentrotus purpuratus. 
  • The role of microparticles in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus. 
  • Tolerability of a new 10% liquid immunoglobulin for intravenous use, Privigen, at different infusion rates. 
  • Translational Research Working Group developmental pathway for immune response modifiers. 
  • Transmission of human immunodeficiency virus to sexual partners of hemophiliacs. 
  • Unusual clinical and immunologic manifestations of transplacentally acquired maternal T cells in severe combined immunodeficiency. 
  • Use of tumor necrosis factor inhibitors in uveitis. 
  • Vincristine therapy for severe platelet alloimmunization. 
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  Keywords of People

  • Allen, Nancy Bates, Professor of Medicine, Medicine, Rheumatology and Immunology
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Cohen-Wolkowiez, Michael, Professor of Pediatrics, Pediatrics, Infectious Diseases
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology