Infant, Premature, Diseases

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  Subject Areas on Research

  • A multi-institution analysis of predictors of timing of inguinal hernia repair among premature infants. 
  • A randomized, controlled trial of platelet transfusions in thrombocytopenic premature infants. 
  • Acute paraplegia in a preterm infant with cerebral sinovenous thrombosis. 
  • Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants. 
  • Adrenal function links to early postnatal growth and blood pressure at age 6 in children born extremely preterm. 
  • Ampicillin dosing in premature infants for early-onset sepsis: exposure-driven efficacy, safety, and stewardship. 
  • Anidulafungin for neonatal hematogenous Candida meningoencephalitis: identification of candidate regimens for humans using a translational pharmacological approach. 
  • Antenatal Betamethasone for Women at Risk for Late Preterm Delivery. 
  • Antenatal magnesium sulfate and spontaneous intestinal perforation in infants less than 25 weeks gestation. 
  • Antenatal magnesium sulfate exposure and acute cardiorespiratory events in preterm infants. 
  • Antenatal magnesium sulphate may prevent cerebral palsy in preterm infants--but are we convinced? Evaluation of an apparently conclusive meta-analysis with trial sequential analysis. 
  • Antibiotic use and misuse in the neonatal intensive care unit. 
  • Antifungal agents and therapy for infants and children with invasive fungal infections: a pharmacological perspective. 
  • Approach to infants born at 22 to 24 weeks' gestation: relationship to outcomes of more-mature infants. 
  • Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight. 
  • Association between Hyperbilirubinemia and Hearing Screen Failure in the Neonatal Intensive Care Unit in Infants Born Preterm. 
  • Association between postmenstrual age and furosemide dosing practices in very preterm infants. 
  • Association of chorioamnionitis and its duration with neonatal morbidity and mortality. 
  • Association of in utero magnesium exposure and spontaneous intestinal perforations in extremely low birth weight infants. 
  • Bacterial endocarditis in infants and children. 
  • Between-hospital variation in treatment and outcomes in extremely preterm infants. 
  • Black Race Is Associated with a Lower Risk of Bronchopulmonary Dysplasia. 
  • Blood stream infection is associated with altered heptavalent pneumococcal conjugate vaccine immune responses in very low birth weight infants. 
  • CT findings and temporal course of persistent pulmonary interstitial emphysema in neonates: a multiinstitutional study. 
  • Candida virulence properties and adverse clinical outcomes in neonatal candidiasis. 
  • Care of the Neonatal Intensive Care Unit Graduate after Discharge. 
  • Case 1: Neonatal Trauma Following Motor Vehicle Collision in Pregnancy. 
  • Case report: total parenteral nutrition extravasation associated with spinal cord compression and necrosis. 
  • Caspofungin for the treatment of azole resistant candidemia in a premature infant. 
  • Causes and timing of death in extremely premature infants from 2000 through 2011. 
  • Changes in cerebral blood volume and cytochrome aa3 during hypertensive peaks in preterm infants. 
  • Clinical characteristics and response to prophylactic fluconazole of preterm VLBW neonates with baseline and acquired fungal colonisation in NICU: data from a multicentre RCT. 
  • Clinical trial design in neonatal pharmacology: effect of center differences, with lessons from the Pediatric Oncology Cooperative Research experience. 
  • Comparative effectiveness of surfactant preparations in premature infants. 
  • Comparative estimates of neonatal gestational maturity by electrographic and fetal ultrasonographic criteria. 
  • Congenital ocular defects associated with an abnormality of the human chromosome 1: trisomy 1q32-qter. 
  • Creatine kinase brain isoenzyme: relationship of cerebrospinal fluid concentration to the neurologic condition of newborns and cellular localization in the human brain. 
  • Critical appraisal of the role of Ureaplasma in the development of bronchopulmonary dysplasia with metaanalytic techniques. 
  • Definitions of cardiovascular insufficiency and relation to outcomes in critically ill newborn infants. 
  • Delay in retinal photoreceptor development in very preterm compared to term infants. 
  • Development of an integrated risk scale for prediction of shunt placement after neonatal intraventricular hemorrhage. 
  • Development of behaviors in preterm infants: relation to sleeping and waking. 
  • Developmental outcome of very low birth weight infants at four years of age as a function of biological risk and psychosocial risk. 
  • Discordance in Antenatal Corticosteroid Use and Resuscitation Following Extremely Preterm Birth. 
  • Disparities in the use of antenatal corticosteroids among women with hypertension in North Carolina. 
  • Do red cell transfusions increase the risk of necrotizing enterocolitis in premature infants? 
  • Does IVIg administration yield improved immune function in very premature neonates? 
  • Dosing and Safety of Off-label Use of Caffeine Citrate in Premature Infants. 
  • Ductus arteriosus in premature infants beyond the second week of life. 
  • Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units. 
  • Early sepsis does not increase the risk of late sepsis in very low birth weight neonates. 
  • Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH Consensus Development Panel on the Effect of Corticosteroids for Fetal Maturation on Perinatal Outcomes. 
  • Effect of fluconazole prophylaxis on candidiasis and mortality in premature infants: a randomized clinical trial. 
  • Effect of gestational age and birth weight on the risk of strabismus among premature infants. 
  • Effect of methicillin-resistant Staphylococcus aureus colonization in the neonatal intensive care unit on total hospital cost. 
  • Elucidating the role of genomics in neonatal sepsis. 
  • Empiric antifungal therapy and outcomes in extremely low birth weight infants with invasive candidiasis. 
  • Empirical antibiotic therapy for suspected early-onset bacterial sepsis. 
  • Evaluation and validation of a prediction model for extubation success in very preterm infants. 
  • Factors associated with feeding progression in extremely preterm infants. 
  • Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy. 
  • Feeding practices and other risk factors for developing transfusion-associated necrotizing enterocolitis. 
  • Furosemide Exposure and Prevention of Bronchopulmonary Dysplasia in Premature Infants. 
  • Gastroschisis: the effect of labor and ruptured membranes on neonatal outcome. 
  • Gastrostomy Tube Feeding in Extremely Low Birthweight Infants: Frequency, Associated Comorbidities, and Long-term Outcomes. 
  • Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants. 
  • Genetic variants associated with severe retinopathy of prematurity in extremely low birth weight infants. 
  • Genetic variation in dopamine neurotransmission and motor development of infants born extremely-low-birthweight. 
  • Genomic analyses: a neonatology perspective. 
  • Gestational age at birth and outcomes after neonatal cardiac surgery: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database. 
  • Health, Physical Growth, and Neurodevelopmental Outcomes in Preterm Infants of Women With Hypertensive Disorders of Pregnancy. 
  • Hemophagocytic lymphohistiocytosis in the premature neonate. 
  • High mortality rates for very low birth weight infants in developing countries despite training. 
  • High-frequency oscillatory ventilation compared with conventional mechanical ventilation in the treatment of respiratory failure in preterm infants. 
  • Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. 
  • Identification of Extremely Premature Infants at Low Risk for Early-Onset Sepsis. 
  • Idiopathic colonic perforation in the neonate. 
  • Immunotherapy in neonatal sepsis: advances in treatment and prophylaxis. 
  • Implementing a Parent Education Program in the Special Care Nursery. 
  • Individual and center-level factors affecting mortality among extremely low birth weight infants. 
  • Infection in late preterm infants. 
  • Influence of gestational age on death and neurodevelopmental outcome in premature infants with severe intracranial hemorrhage. 
  • Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial. 
  • Intestinal fatty-acid binding protein and metronidazole response in premature infants. 
  • Intrauterine epidermal necrosis. 
  • Intussusception in the Neonate: A Case Study. 
  • Iron overload following red blood cell transfusion and its impact on disease severity. 
  • Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants? 
  • Late-onset sepsis in very low birth weight infants from singleton and multiple-gestation births. 
  • Limitation of pulsatility index as a diagnostic tool in the newborn. 
  • Management of 239 patients with hypoplastic left heart syndrome and related malformations from 1993 to 2007. 
  • Meningitis in preterm neonates: importance of cerebrospinal fluid parameters. 
  • Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018. 
  • Natural history of neonatal herpes simplex virus infections in the acyclovir era. 
  • Negative Temperature Differential in Preterm Infants Less Than 29 Weeks Gestational Age: Associations With Infection and Maternal Smoking. 
  • Neonatal Thermoregulation: A Golden Hour Protocol Update. 
  • Neonatal candidiasis: epidemiology, risk factors, and clinical judgment. 
  • Neonatal complications after the administration of indomethacin for preterm labor. 
  • Neonatal fungal infections: when to treat? 
  • Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. 
  • Neurodevelopmental and Behavioral Outcomes in Extremely Premature Neonates With Ventriculomegaly in the Absence of Periventricular-Intraventricular Hemorrhage. 
  • Neurodevelopmental outcome of extremely low birth weight infants with Candida infection. 
  • Neurodevelopmental outcome of infants with unilateral or bilateral periventricular hemorrhagic infarction. 
  • Neurodevelopmental outcomes following neonatal late-onset sepsis and blood culture-negative conditions. 
  • Neurologic Outcome After Prematurity: Perspectives of Parents and Clinicians. 
  • Nursery neurobiologic risk score: levels of risk and relationships with nonmedical factors. 
  • Nursing care and the development of sleeping and waking behaviors in preterm infants. 
  • Nursing care of the premature infant with severe combined immunodeficiency disease. 
  • Nutrition and hearing loss: a neglected cause and global health burden. 
  • Optimal body temperature in transitional extremely low birth weight infants using heart rate and temperature as indicators. 
  • Outcomes of Extremely Preterm Infants With Birth Weight Less Than 400 g. 
  • PROLONGED RUPTURE OF FETAL MEMBRANES. 
  • PaCO2 in surfactant, positive pressure, and oxygenation randomised trial (SUPPORT). 
  • Patterns of Oxygenation, Mortality, and Growth Status in the Surfactant Positive Pressure and Oxygen Trial Cohort. 
  • Patterns of phlebotomy blood loss and transfusions in extremely low birth weight infants. 
  • Pediatric Obstructive Sleep Apnea in High-Risk Populations: Clinical Implications. 
  • Perioperative methylprednisolone and outcome in neonates undergoing heart surgery. 
  • Pharmacokinetic profile of caffeine in the premature newborn infant with apnea. 
  • Pharmacological resolution of a multiloculated Candida spp. liver abscess in a preterm neonate. 
  • Population pharmacokinetics of sildenafil in extremely premature infants. 
  • Postconception age and other risk factors associated with mortality following Gram-negative rod bacteremia. 
  • Predicting time to hospital discharge for extremely preterm infants. 
  • Probiotic Use and Safety in the Neonatal Intensive Care Unit: A Matched Cohort Study. 
  • Progressive hepatic injury in prolonged parenteral alimentation. 
  • Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infants. 
  • Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants. 
  • Recovery from disseminated candidiasis in a premature neonate. 
  • Regarding: Optimal timing for inguinal hernia repair in premature infants: A systematic review and meta-analysis. 
  • Relationship of neonatal treatments with the development of necrotizing enterocolitis in preterm infants. 
  • Respiratory Medications in Infants <29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium. 
  • Risk factors and prevention of late-onset sepsis in premature infants. 
  • Risk factors for necrotizing enterocolitis in preterm infants: how race, gender, and health status contribute. 
  • Risk of neonatal and childhood morbidity among preterm infants exposed to marijuana. 
  • Safety of sildenafil in extremely premature infants: a phase I trial. 
  • Safety of sildenafil in premature infants with severe bronchopulmonary dysplasia (SILDI-SAFE): a multicenter, randomized, placebo-controlled, sequential dose-escalating, double-masked, safety study. 
  • Serum tocopherol levels in very preterm infants after a single dose of vitamin E at birth. 
  • Sildenafil Exposure in the Neonatal Intensive Care Unit. 
  • Sleep-Wake States and Feeding Progression in Preterm Infants. 
  • Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin. 
  • Surfactant Administration in Preterm Infants: Drug Development Opportunities. 
  • Survival and Neurodevelopmental Outcomes among Periviable Infants. 
  • Survival, Morbidities, and Developmental Outcomes among Low Birth Weight Infants with Congenital Heart Defects. 
  • Systemic Torulopsis glabrata infection in a neonate. 
  • The Association Between Very Premature Infant Body Temperatures Over Time and Respiratory Care. 
  • The Association of Hydrocortisone Dosage on Mortality in Infants Born Extremely Premature. 
  • The association of rapid volume expansion and intraventricular hemorrhage in the preterm infant. 
  • The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants. 
  • The use of antifungal therapy in neonatal intensive care. 
  • Thermoregulation and heat loss prevention after birth and during neonatal intensive-care unit stabilization of extremely low-birthweight infants. 
  • Thinner Retinal Nerve Fiber Layer in Very Preterm Versus Term Infants and Relationship to Brain Anatomy and Neurodevelopment. 
  • Thyroid hormone levels in term and preterm neonates. 
  • Tracheostomy After Operations for Congenital Heart Disease: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database. 
  • Transient myeloproliferative disease: keeping a high index of suspicion. 
  • Treatment and prophylaxis of invasive candidiasis. 
  • Treatment outcomes of necrotizing enterocolitis for preterm infants. 
  • Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012. 
  • Unilateral shoulder swelling in a preterm neonate. 
  • Uptake of a Guideline for the Administration of a Rescue Course of Antenatal Corticosteroids. 
  • Urine bombesin-like peptide elevation precedes clinical evidence of bronchopulmonary dysplasia. 
  • Urine gastrin-releasing peptide in the first week correlates with bronchopulmonary dysplasia and post-prematurity respiratory disease. 
  • Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. 
  • Use of Placental/Umbilical Blood Sampling for Neonatal Admission Blood Cultures: Benefits, Challenges, and Strategies for Implementation. 
  • Use of Reflux Medications in Premature Infants After Hospital Discharge. 
  • Use of a Midliner Positioning System for Prevention of Dolichocephaly in Preterm Infants. 
  • Use of antihypotensive therapies in extremely preterm infants. 
  • Value of sonography in the diagnosis of intracranial hemorrhage and periventricular leukomalacia: a postmortem study of 35 cases. 
  • Variation in Gastrostomy Tube Placement in Premature Infants in the United States. 
  • Very late onset infections in the neonatal intensive care unit. 
  • Very low birth weight neonates who survive early-onset sepsis do not have an increased risk of developing late-onset sepsis. 
  • Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003. 
  • Vocal fold paralysis following surgical ductal closure in extremely low birth weight infants: a case series of feeding and respiratory complications. 
  • When to suspect fungal infection in neonates: A clinical comparison of Candida albicans and Candida parapsilosis fungemia with coagulase-negative staphylococcal bacteremia. 
  • Wide range of perioperative drugs and doses used in inguinal hernia repairs for premature infants. 
  • Wide variation in caffeine discontinuation timing in premature infants. 
  • Zygomycosis in neonates: an uncommon but life-threatening infection. 
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  Keywords of People

  • Bradford, William Dalton, Professor of Pathology, Pathology
  • Cohen-Wolkowiez, Michael, Kiser-Arena Distinguished Professor, Pediatrics, Infectious Diseases
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology