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Subject Areas on Research
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A New Protocol for Anticoagulation With Tirofiban During Flow Diversion.
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A Phase 1 Randomized Study of Single Intravenous Infusions of the Novel Nitroxyl Donor BMS-986231 in Healthy Volunteers.
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A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours.
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A Phase II study of Bcl-2 antisense (oblimersen sodium) combined with gemtuzumab ozogamicin in older patients with acute myeloid leukemia in first relapse.
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A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse.
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A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics.
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A Southwest Oncology Group Randomized Phase II Study of doxorubicin and paclitaxel as frontline chemotherapy for women with metastatic breast cancer.
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A Trial of Hyperimmune Globulin to Prevent Congenital Cytomegalovirus Infection.
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A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis.
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A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
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A chronic sheep preparation for the study of drug pharmacokinetics in spinal and ventricular CSF.
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A comparison of 3% hypertonic saline and mannitol for brain relaxation during elective supratentorial brain tumor surgery.
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A computerized physician order entry set designed to improve safety of intravenous haloperidol utilization: a retrospective study in agitated hospitalized patients.
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A multi-centre randomized phase II study of nolatrexed versus doxorubicin in treatment of Chinese patients with advanced hepatocellular carcinoma.
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A phase I multicenter study of continuous oral administration of lonafarnib (SCH 66336) and intravenous gemcitabine in patients with advanced cancer.
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A phase I study of the safety and pharmacokinetics of edotecarin (J-107088), a novel topoisomerase I inhibitor, in patients with advanced solid tumors.
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A phase II pilot study of high-dose 24-hour continuous infusion of 5-FU and leucovorin and low-dose PALA for patients with colorectal cancer: a Southwest Oncology Group study.
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A phase II study of high-dose 24 hour continuous infusion 5-FU and leucovorin and low-dose PALA for patients with advanced pancreatic adenocarcinoma: a Southwest Oncology Group Study.
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A phase II study of recombinant interferon-gamma following combination chemotherapy for patients with extensive small cell lung cancer. CALGB.
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A phase II trial of 6-hydroxymethylacylfulvene (MGI-114, irofulven) in patients with relapsed or refractory non-small cell lung cancer.
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A phase II trial of docetaxel and bevacizumab in recurrent ovarian cancer within 12 months of prior platinum-based chemotherapy.
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A physiologic role for somatostatin 28 as a regulator of insulin secretion.
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A pilot study to determine the feasibility of continuous cefazolin infusion.
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A pooled analysis of coronary arterial patency and left ventricular function after intravenous thrombolysis for acute myocardial infarction.
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A randomized evaluation of bispectral index-augmented sedation assessment in neurological patients.
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A randomized phase II study of PX-12, an inhibitor of thioredoxin in patients with advanced cancer of the pancreas following progression after a gemcitabine-containing combination.
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A randomized study of alglucosidase alfa in late-onset Pompe's disease.
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A randomized trial comparing the efficacy and safety of imiglucerase (Cerezyme) infusions every 4 weeks versus every 2 weeks in the maintenance therapy of adult patients with Gaucher disease type 1.
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A randomized trial of intravenous heparin in conjunction with anistreplase (anisoylated plasminogen streptokinase activator complex) in acute myocardial infarction: the Duke University Clinical Cardiology Study (DUCCS) 1.
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A randomized trial of phenylephrine infusion versus bolus dosing for nausea and vomiting during Cesarean delivery in obese women.
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A randomized, open-label study of the safety and tolerability of fospropofol for patients requiring intubation and mechanical ventilation in the intensive care unit.
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A reliable and cost-effective neonatal aminoglycoside administration system.
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A retrospective analysis of cross-reacting cetuximab IgE antibody and its association with severe infusion reactions.
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A reversible aptamer improves outcome and safety in murine models of stroke and hemorrhage.
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A single infusion of zoledronic acid produces sustained remissions in Paget disease: data to 6.5 years.
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ASCO Value Framework Highlights the Relative Value of Treatment Options in Ovarian Cancer.
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Acute Treatment With Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure: The ATOMIC-AHF Study.
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Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans.
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Acute tolerance and reversal of the motor control effects of midazolam.
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Addition of bevacizumab to fluorouracil-based first-line treatment of metastatic colorectal cancer: pooled analysis of cohorts of older patients from two randomized clinical trials.
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Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer.
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Adolescent-onset nicotine self-administration modeled in female rats.
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Adrenocortical sensitivity to ACTH in humans.
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Adrenocortical sensitivity to low-dose ACTH administration in depressed patients.
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Aerobic training as an adjunctive therapy to enzyme replacement in Pompe disease.
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Alcohol spray vs. intradermal lidocaine before intravenous cannulation.
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Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty.
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Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
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Alterations in polyamine metabolism during continuous intravenous infusion of alpha-difluoromethylornithine showing correlation of thrombocytopenia with alpha-difluoromethylornithine plasma levels.
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Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice.
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An automated strategy for bedside aPTT determination and unfractionated heparin infusion adjustment in acute coronary syndromes: insights from PARAGON A.
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An evaluation of several biochemical markers for bone formation and resorption in a protocol utilizing cyclical parathyroid hormone and calcitonin therapy for osteoporosis.
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An individually, modified approach to desensitize infants and young children with Pompe disease, and significant reactions to alglucosidase alfa infusions.
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An initial multicenter, randomized controlled trial on the safety and efficacy of acadesine in patients undergoing coronary artery bypass graft surgery. SPI Research Group.
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An open-label clinical trial evaluating safety and pharmacokinetics of two dosing schedules of panitumumab in patients with solid tumors.
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Analysis of the brain bioavailability of peripherally administered magnesium sulfate: A study in humans with acute brain injury undergoing prolonged induced hypermagnesemia.
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Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.
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Angiographic outcomes with early eptifibatide therapy in non-ST-segment elevation acute coronary syndrome (from the EARLY ACS Trial).
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Anti-Myelin Oligodendrocyte Glycoprotein Optic Neuritis or Neuroretinitis?
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Antianginal effects of intravenous nitroglycerin over 24 hours.
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Anticoagulant responses to thrombin are enhanced during regression of atherosclerosis in monkeys.
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Antiemetics: American Society of Clinical Oncology clinical practice guideline update.
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Antimetabolite therapy for lesser-risk B-lineage acute lymphoblastic leukemia of childhood: a report from Children's Oncology Group Study P9201.
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Antiresorptive effect of a single infusion of microgram quantities of zoledronate in Paget's disease of bone.
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Antithrombotic potencies of enoxaparin in microvascular surgery: influence of dose and administration methods on patency rate of crushed arterial anastomoses.
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Application of antimicrobial stewardship to optimise management of community acquired pneumonia.
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Applying the new STEMI guidelines: 1. Reperfusion in acute ST-segment elevation myocardial infarction.
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Are Prophylactic Postoperative Antibiotics Necessary for Immediate Breast Reconstruction? Results of a Prospective Randomized Clinical Trial.
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Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI): a multicenter, randomized, double-blind, parallel-group, placebo-controlled study of pexelizumab in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention.
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Assessment of the optimal temporal window for intravenous CT cholangiography.
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Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients With Acute Ischemic Stroke.
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Association between timing of zoledronic acid infusion and hip fracture healing.
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Association of guideline publication and delays to treatment in pediatric status epilepticus.
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Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries.
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Atrial natriuretic hormone, vessel dilator, long acting natriuretic hormone, and kaliuretic hormone decrease circulating prolactin concentrations.
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Atrial natriuretic hormone, vessel dilator, long-acting natriuretic hormone, and kaliuretic hormone decrease the circulating concentrations of total and tree T4 and free T3 with reciprocal increase in TSH.
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Attenuation of counterregulatory responses to recurrent hypoglycemia by active thalamic inhibition: a mechanism for hypoglycemia-associated autonomic failure.
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Auto-SCT for AML in second remission: CALGB study 9620.
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Back to the Future With Intravenous Diuretics: Reinvigorating an Old Treatment Through New Care Settings.
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Barriers to mobility during hospitalization from the perspectives of older patients and their nurses and physicians.
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Behavioral indications for serotonin receptor hypersensitivity in panic disorder.
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Benefit of glycoprotein IIb/IIIa inhibition in patients with acute coronary syndromes and troponin t-positive status: the paragon-B troponin T substudy.
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Biased ligand of the angiotensin II type 1 receptor in patients with acute heart failure: a randomized, double-blind, placebo-controlled, phase IIB, dose ranging trial (BLAST-AHF).
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Bioactivity of intraduodenally and intravenously infused fragments of luminal cholecystokinin releasing factor (LCRF).
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Bisphosphonate-associated arthritis.
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Blocking of responses to endotoxin by E5564 in healthy volunteers with experimental endotoxemia.
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Bolus magnesium infusion in humans is associated with predominantly unfavourable changes in platelet aggregation and certain haemostatic factors.
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Brain neurotransmitter turnover rates during rat intravenous cocaine self-administration.
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Brain oxygenation and CNS oxygen toxicity after infusion of perfluorocarbon emulsion.
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Brief report: effect of intravenous methotrexate dose and infusion rate on neuropsychological function one year after diagnosis of acute lymphoblastic leukemia.
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Bronchospasm after intravenous adenosine administration.
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CACI in cardiac surgery.
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COVID-19 and ovarian cancer: Exploring alternatives to intravenous (IV) therapies.
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Candidal anastomotic infection in lung transplant recipients: successful treatment with a combination of systemic and inhaled antifungal agents.
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Carboplatin and vinblastine in advanced non-small-cell lung cancer: a phase II study.
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Cardiac remodeling after enzyme replacement therapy with acid alpha-glucosidase for infants with Pompe disease.
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Cardiac rupture, mortality and the timing of thrombolytic therapy: a meta-analysis.
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Case 4-2007. Aprotinin-induced cardiovascular collapse after a negative test dose in a patient scheduled for repeat mitral valve surgery.
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Catheter-related sepsis refractory to antibiotics treated successfully with adjunctive urokinase infusion.
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Ceftaroline fosamil for treatment of community-acquired pneumonia: findings from FOCUS 1 and 2 and potential role in therapy.
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Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease.
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Cerebral blood flow changes during sodium-lactate-induced panic attacks.
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Characteristics and outcome of patients in whom reperfusion with intravenous tissue-type plasminogen activator fails: results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) I trial.
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Characteristics of patients that do not initially respond to intravenous antihypertensives in the emergency department: subanalysis of the CLUE trial.
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Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT).
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Chemotherapy experts.
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Chemotherapy in the management of intraocular lymphoma.
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Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia.
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Chinese hamster ovary cell-derived recombinant human acid alpha-glucosidase in infantile-onset Pompe disease.
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Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions.
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Cholecystokinin does not stimulate prosomatostatin-derived peptides in man.
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Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels.
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Chronic inflammatory demyelinating polyradiculoneuropathy of childhood: treatment with high-dose intravenous immunoglobulin.
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Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes.
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Cisplatin and 5-fluorouracil infusion for metastatic colorectal carcinoma. Differences in survival in two patient groups with similar response rates.
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Cisplatin and infusional cytosine arabinoside for the treatment of colorectal adenocarcinoma: a phase II trial.
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Clevidipine in the treatment of perioperative hypertension: assessing safety events in the ECLIPSE trials.
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Clinical and therapeutic profile of patients presenting with acute coronary syndromes who do not have significant coronary artery disease.The Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy (PURSUIT) Trial Investigators.
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Clinical efficacy and safety of intracoronary vs. intravenous abciximab administration in STEMI patients undergoing primary percutaneous coronary intervention: a meta-analysis of randomized trials.
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Collaborative angiographic patency trial of recombinant staphylokinase (CAPTORS).
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Combination therapy with anti-HIV-1 antibodies maintains viral suppression.
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Combined Tc-99m sestamibi first-pass radionuclide angiography and cardiac SPECT imaging during arbutamine infusion delivered by a computerized closed-loop system.
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Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial. IMPACT-AMI Investigators.
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Combined treatment with vessel dilator and kaliuretic hormone in persons with congestive heart failure.
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Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias.
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Comparison of a single infusion of zoledronic acid with risedronate for Paget's disease.
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Comparison of caspofungin and amphotericin B for invasive candidiasis.
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Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised children and healthy adults.
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Comparison of postoperative pain outcomes after vertical or Pfannenstiel incision for major gynecologic surgery.
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Comparison of the effects of IL-1 alpha and TNF-alpha on phagocyte accumulation and murine antibacterial immunity.
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Comparison of the safety and efficacy of intravenous ciprofloxacin and intravenous ceftazidime in the treatment of selected infections.
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Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents.
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Comparison of vessel dilator and long-acting natriuretic peptide in the treatment of congestive heart failure.
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Compatibility and stability of bryostatin 1 in infusion devices.
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Compatibility of aminophylline and verapamil in intravenous admixtures.
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Complete atrioventricular block complicating inferior wall acute myocardial infarction treated with reperfusion therapy. TAMI Study Group.
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Complex Role for E-Prostanoid 4 Receptors in Hypertension.
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Concentrated albumin infusion as an aid to postoperative recovery after pelvic exenteration.
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Continuous IV Crotalidae Polyvalent Immune Fab (Ovine) (FabAV) for selected North American rattlesnake bite patients.
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Continuous infusion 5-fluorouracil as first-line therapy for metastatic breast cancer.
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Continuous infusion prochlorperazine: pharmacokinetics, antiemetic efficacy, and feasibility of high-dose therapy.
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Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
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Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST).
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Continuous intravenous epoprostenol for chronic thromboembolic pulmonary hypertension.
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Continuous intravenous infusion of epoprostenol for the treatment of portopulmonary hypertension.
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Continuous intravenous quinidine infusion for the treatment of atrial fibrillation or flutter: a case series.
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Continuous versus bolus dosing of Furosemide for patients hospitalized for heart failure.
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Control of plasma uric acid in adults at risk for tumor Lysis syndrome: efficacy and safety of rasburicase alone and rasburicase followed by allopurinol compared with allopurinol alone--results of a multicenter phase III study.
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Converting i.v. nitroglycerin therapy to nitroglycerin ointment therapy: a comparison of two methods.
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Coronary arterial thrombolysis with combined infusion of recombinant tissue-type plasminogen activator and urokinase in patients with acute myocardial infarction.
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Cost effectiveness of intraperitoneal compared with intravenous chemotherapy for women with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study.
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Cost impact of oral capecitabine compared to intravenous taxane-based chemotherapy in first-line metastatic breast cancer.
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Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure.
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Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial.
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Defining regional infusion treatment strategies for extremity melanoma: comparative analysis of melphalan and temozolomide as regional chemotherapeutic agents.
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Delays in fibrinolysis as primary reperfusion therapy for acute ST-segment elevation myocardial infarction.
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Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies.
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Design of the RELAXin in acute heart failure study.
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Determinants of the need for early acute intervention in patients treated conservatively after thrombolytic therapy for acute myocardial infarction. TAMI-5 Study Group.
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Dexmedetomidine infusion for sedation during fiberoptic intubation: a report of three cases.
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Dexmedetomidine pharmacodynamics: Part II: Crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers.
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Dexmedetomidine pharmacodynamics: part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers.
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Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans.
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Disposition of vessel dilator and long-acting natriuretic peptide in healthy humans after a one-hour infusion.
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Diuretic strategies in patients with acute decompensated heart failure.
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Duke procedure for super obesity: preliminary report with 3.5-year follow-up.
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Duration of eptifibatide infusion after percutaneous coronary intervention and outcomes among high-risk patients with non-ST-segment elevation acute coronary syndrome: insights from EARLY ACS.
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During acute hypercapnia vasopressin inhibits an angiotensin drive to ventilation in conscious dogs.
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Duvoglustat HCl Increases Systemic and Tissue Exposure of Active Acid α-Glucosidase in Pompe Patients Co-administered with Alglucosidase α.
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EDTA chelation therapy alone and in combination with oral high-dose multivitamins and minerals for coronary disease: The factorial group results of the Trial to Assess Chelation Therapy.
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Early diuretic strategies and the association with In-hospital and Post-discharge outcomes in acute heart failure.
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Early drop in systolic blood pressure and worsening renal function in acute heart failure: renal results of Pre-RELAX-AHF.
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Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study.
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Early intravenous heart failure therapy and outcomes among older patients hospitalized for acute decompensated heart failure: findings from the Acute Decompensated Heart Failure Registry Emergency Module (ADHERE-EM).
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Early management of acute severe asthma.
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Early versus delayed, provisional eptifibatide in acute coronary syndromes.
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Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.
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Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty. EPIC Investigators.
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Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial.
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Effect of Etelcalcetide vs Placebo on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: Two Randomized Clinical Trials.
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Effect of Ularitide on Cardiovascular Mortality in Acute Heart Failure.
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Effect of admission oral diuretic dose on response to continuous versus bolus intravenous diuretics in acute heart failure: an analysis from diuretic optimization strategies in acute heart failure.
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Effect of continuous complement inhibition using soluble complement receptor type 1 on survival of pig-to-primate cardiac xenografts.
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Effect of disodium EDTA chelation regimen on cardiovascular events in patients with previous myocardial infarction: the TACT randomized trial.
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Effect of eptifibatide on coronary flow reserve following coronary stent implantation (an ESPRIT substudy). Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy.
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Effect of glycemia on plasma incretins and the incretin effect during oral glucose tolerance test.
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Effect of infusion rate on thiopental dose-response relationships. Assessment of a pharmacokinetic-pharmacodynamic model.
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Effect of intravenous alpha-difluoromethylornithine on the polyamine levels of normal tissue and a transplantable fibrosarcoma.
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Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial.
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Effect of magnesium sulphate infusion on ex vivo platelet aggregation in swine.
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Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study.
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Effect of normal saline bolus on cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage.
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Effect of rifampicin on S-ketamine and S-norketamine plasma concentrations in healthy volunteers after intravenous S-ketamine administration.
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Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial.
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Effect of virtual reality on time perception in patients receiving chemotherapy.
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Effect of zoledronic acid on pain associated with bone metastasis in patients with prostate cancer.
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Effective initial therapy of advanced breast cancer with fluorouracil and high-dose, continuous infusion calcium leucovorin.
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Effective pelvic symptom control using initial chemoradiation without colostomy in metastatic rectal cancer.
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Effectiveness of Prevention Strategies for Contrast-Induced Nephropathy: A Systematic Review and Meta-analysis.
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Effects of C5 complement inhibitor pexelizumab on outcome in high-risk coronary artery bypass grafting: combined results from the PRIMO-CABG I and II trials.
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Effects of Serelaxin in Patients with Acute Heart Failure.
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Effects of cardiac glycosides on atrial contractile dysfunction after short-term atrial fibrillation.
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Effects of dose ranging of adenosine infusion on electrocardiographic findings during and after general anesthesia.
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Effects of kaliuretic peptide on sodium and water excretion in persons with congestive heart failure.
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Effects of low-dose atrial natriuretic peptide infusion on cardiac surgery-associated acute kidney injury: A multicenter randomized controlled trial.
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Effects of magnesium supplementation in a porcine model of myocardial ischemia and reperfusion.
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Effects of serelaxin in subgroups of patients with acute heart failure: results from RELAX-AHF.
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Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials.
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Efficacy and safety of a once-yearly intravenous zoledronic acid 5 mg for fracture prevention in elderly postmenopausal women with osteoporosis aged 75 and older.
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Efficacy and safety of recombinant factor XIII on reducing blood transfusions in cardiac surgery: a randomized, placebo-controlled, multicenter clinical trial.
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Efficacy and tolerance of high-dose intravenous amiodarone for recurrent, refractory ventricular tachycardia.
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Efficacy of intracoronary or intravenous VEGF165 in a pig model of chronic myocardial ischemia.
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Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome.
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Efficacy of pamidronate for osteoporosis in patients with cystic fibrosis following lung transplantation.
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Efficacy of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: one-year follow-up results of the Assessment of the Safety of a New Thrombolytic-3 (ASSENT-3) randomized trial in acute myocardial infarction.
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Enzyme replacement therapy with alglucosidase alfa in Pompe disease: Clinical experience with rate escalation.
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Ethylenecarbodiimide-fixed donor splenocyte infusions differentially target direct and indirect pathways of allorecognition for induction of transplant tolerance.
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Evaluation of Biomarkers of Oxidative Stress and Apoptosis in Patients With Severe Methotrexate Neurotoxicity: A Case Series.
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Evaluation of Kawasaki disease risk-scoring systems for intravenous immunoglobulin resistance.
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Evaluation of a prolonged infusion of recombinant tissue-type plasminogen activator (Duteplase) in preventing reocclusion following successful thrombolysis in acute myocardial infarction.
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Evaluation of continuous-infusion alpha-difluoromethylornithine therapy for colorectal carcinoma.
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FK 506 rescue therapy for resistant rejection episodes in liver transplant recipients.
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FK506 in combination with methotrexate for the prevention of graft-versus-host disease after marrow transplantation from matched unrelated donors.
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Failure of glucagon-like peptide-1 to induce panic attacks or anxiety in patients with panic disorder.
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Failure of low molecular weight dextran to prevent clotting during continuous renal replacement therapy.
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Feedback regulation of angiotensin converting enzyme activity and mRNA levels by angiotensin II.
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Ferric carboxymaltose in patients with iron-deficiency anemia and impaired renal function: the REPAIR-IDA trial.
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First experience with direct factor Xa inhibition in patients with stable coronary disease: a pharmacokinetic and pharmacodynamic evaluation.
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Fludarabine followed by alemtuzumab consolidation for previously untreated chronic lymphocytic leukemia: final report of Cancer and Leukemia Group B study 19901.
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Fluid removal in acute heart failure: diuretics versus devices.
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Frequency, clinical and angiographic characteristics, and outcomes of high-risk non-ST-segment elevation acute coronary syndromes patients with left circumflex culprit lesions.
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Gemcitabine for malignant mesothelioma: A phase II trial by the Cancer and Leukemia Group B.
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Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration.
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Genome-wide study of methotrexate clearance replicates SLCO1B1.
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Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal.
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Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats.
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Glutamine as indispensable nutrient in oncology: experimental and clinical evidence.
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Haemodynamic effects, safety, and pharmacokinetics of human stresscopin in heart failure with reduced ejection fraction.
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Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study.
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Heparin management in acute myocardial infarction (AMI).
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Hepatic haemodynamic changes following inhibition of endothelium-derived relaxing and hyperpolarising factors in anaesthetised miniature pigs.
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High-dose dexmedetomidine sedation for pediatric MRI.
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High-dose infusional doxorubicin and cyclophosphamide: a feasibility study of tandem high-dose chemotherapy cycles without stem cell support.
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Hospital variation in intravenous inotrope use for patients hospitalized with heart failure: insights from Get With The Guidelines.
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How magnesium therapy may influence clinical outcome in acute myocardial infarction: review of potential mechanisms.
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Human brain glycogen metabolism during and after hypoglycemia.
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Hydrostatic isolated limb perfusion with adeno-associated virus vectors enhances correction of skeletal muscle in Pompe disease.
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Hyperkalemia associated with intravenous labetalol therapy for acute hypertension in renal transplant recipients.
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Hyponatremia and Hypotonic Intravenous Fluids Are Associated With Unfavorable Outcomes of Bronchiolitis Admissions.
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Idarucizumab for Dabigatran Reversal - Full Cohort Analysis.
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Idarucizumab for Dabigatran Reversal.
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Idiopathic autoimmune thrombocytopenic purpura.
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Ifosfamide enantiomers: pharmacokinetics in children.
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Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart.
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Immunomodulatory and antimicrobial efficacy of intravenous immunoglobulin in bone marrow transplantation.
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Impact of Reduced Preincision Antibiotic Infusion Time on Surgical Site Infection Rates: A Retrospective Cohort Study.
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Impact of intravenous beta-blockade before primary angioplasty on survival in patients undergoing mechanical reperfusion therapy for acute myocardial infarction.
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Impact of intravenous lidocaine infusion on postoperative analgesia and recovery from surgery: a systematic review of randomized controlled trials.
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Impaired insulin response after oral but not intravenous glucose in heart- and liver-transplant recipients.
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Implementation of a smart pump champions program to decrease potential patient harm.
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In vitro intravenous fluid co-load rates with and without an intravenous fluid warming device.
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In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors.
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Incidence and predictors of bleeding events after fibrinolytic therapy with fibrin-specific agents: a comparison of TNK-tPA and rt-PA.
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Infiltration of sodium valproate with compartment syndrome and bullous reaction: case report and literature review.
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Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group.
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Infliximab maintenance therapy for fistulizing Crohn's disease.
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Influence of St. John's Wort on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics, and Clinical Effects: A Randomized Clinical Trial.
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Influence of intravenous amifostine on xerostomia, tumor control, and survival after radiotherapy for head-and- neck cancer: 2-year follow-up of a prospective, randomized, phase III trial.
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Influence of skin site on bioavailability of nitroglycerin ointment in congestive heart failure.
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Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial.
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Inhaled epoprostenol during one-lung ventilation.
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Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled Trial.
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Inhibition of the transcriptional activator protein nuclear factor kappaB prevents hemodynamic instability associated with the whole-body inflammatory response syndrome.
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Inotropic therapy for heart failure: an evidence-based approach.
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Insights derived from the thrombolysis and angioplasty in myocardial infarction (TAMI) trials.
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Insulin and glucosamine infusions increase O-linked N-acetyl-glucosamine in skeletal muscle proteins in vivo.
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Intensive concomitant chemoradiotherapy in locally advanced unresectable squamous cell carcinoma of the head and neck: a phase II study of radiotherapy with cisplatin and 7-week continuous infusional fluorouracil.
-
Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B.
-
Intestinal fatty-acid binding protein and metronidazole response in premature infants.
-
Intracranial haemorrhage with bolus thrombolytic agents.
-
Intracranial haemorrhage with bolus thrombolytic agents.
-
Intracranial pressure and hemodynamic effects of remifentanil versus alfentanil in patients undergoing supratentorial craniotomy.
-
Intraperitoneal chemotherapy following neoadjuvant chemotherapy and optimal interval tumor reductive surgery for advanced ovarian cancer.
-
Intravenous 6-thioguanine or cisplatin, fluorouracil and leucovorin for advanced non-small cell lung cancer: a randomized phase II study of the cancer and leukemia group B.
-
Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.
-
Intravenous Iron-Induced Hypophosphatemia: An Emerging Syndrome.
-
Intravenous acetaminophen analgesia after cardiac surgery: A randomized, blinded, controlled superiority trial.
-
Intravenous adenosine selectively increases blood flow to xenotransplanted intracerebral gliomas.
-
Intravenous fluids in sepsis: what to use and what to avoid.
-
Intravenous immune globulin prophylaxis in recipients of a marrow transplant.
-
Intravenous magnesium sulfate does not increase ventricular CSF ionized magnesium concentration of patients with intracranial hypertension.
-
Intravenous micronutrient therapy (Myers' Cocktail) for fibromyalgia: a placebo-controlled pilot study.
-
Intravenous thrombolysis in acute myocardial infarction.
-
Intraventricular CCK inhibits food intake and gastric emptying in baboons.
-
Irinotecan for malignant mesothelioma A phase II trial by the Cancer and Leukemia Group B.
-
Isoproterenol inhibits the increase in microvascular membrane permeability produced by bradykinin.
-
Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery.
-
Long-term control of bone turnover in Paget's disease with zoledronic acid and risedronate.
-
Long-term protection from myocardial ischemic events in a randomized trial of brief integrin beta3 blockade with percutaneous coronary intervention. EPIC Investigator Group. Evaluation of Platelet IIb/IIIa Inhibition for Prevention of Ischemic Complication.
-
Longitudinal Toxicity over Time (ToxT) analysis to evaluate tolerability: a case study of lenalidomide in the CALGB 50401 (Alliance) trial.
-
Low bias flow oscillation with heliox in oleic acid-induced lung injury.
-
Low lymphocyte ratio as a novel prognostic factor in acute heart failure: results from the Pre-RELAX-AHF study.
-
Low molecular weight heparin (dalteparin) compared to unfractionated heparin as an adjunct to rt-PA (alteplase) for improvement of coronary artery patency in acute myocardial infarction-the ASSENT Plus study.
-
Low-dose unenhanced CT for IV contrast bolus timing: is it reliable to assess hepatic steatosis?
-
Lurbinectedin versus pegylated liposomal doxorubicin or topotecan in patients with platinum-resistant ovarian cancer: A multicenter, randomized, controlled, open-label phase 3 study (CORAIL).
-
Maintenance of therapeutic plasma aprotinin levels during prolonged cardiopulmonary bypass using a large-dose regimen.
-
Maji: a new tool to prevent overhydration of children receiving intravenous fluid therapy in low-resource settings.
-
Management of myasthenic crisis: continuous anticholinesterase infusions.
-
Mannitol bolus preferentially shrinks non-infarcted brain in patients with ischemic stroke.
-
Massive pulmonary edema and death after prostacyclin infusion in a patient with pulmonary veno-occlusive disease.
-
Maximizing local control and organ preservation in stage IV squamous cell head and neck cancer With hyperfractionated radiation and concurrent chemotherapy.
-
Medical therapy for acute ischemic stroke.
-
Meta-analysis of high- versus low-chloride content in perioperative and critical care fluid resuscitation.
-
Meta-analysis of survival with platelet glycoprotein IIb/IIIa antagonists for percutaneous coronary interventions.
-
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants.
-
Methemoglobinemia after infusion of ifosfamide chemotherapy: first report of a potentially serious adverse reaction related to ifosfamide.
-
Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis.
-
Mitomycin C and menadione for the treatment of lung cancer: a phase II trial.
-
Modern medical management of acute ischemic stroke.
-
Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome.
-
Multiagent concurrent chemoradiotherapy for locoregionally advanced squamous cell head and neck cancer: mature results from a single institution.
-
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.
-
Multicenter phase II study of a 28-day regimen of orally administered eniluracil and fluorouracil in the treatment of patients with anthracycline- and taxane-resistant advanced breast cancer.
-
Multicenter randomized trial and a systematic overview of lidocaine in acute myocardial infarction.
-
Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. IMPACT Investigators.
-
NCIC CTG IND.181: phase I study of AT9283 given as a weekly 24 hour infusion in advanced malignancies.
-
Neoadjuvant chemoradiation for distal rectal cancer: 5-year updated results of a randomized phase 2 study of neoadjuvant combined modality chemoradiation for distal rectal cancer.
-
Neutrophil migration is defective during recombinant human granulocyte-macrophage colony-stimulating factor infusion after autologous bone marrow transplantation in humans.
-
Niacin-like reaction to infliximab infusion in systemic juvenile rheumatoid arthritis.
-
Nicotine and nonnicotine factors in cigarette addiction.
-
Ninety-six hour ketamine infusion with co-administered clonidine for treatment-resistant depression: A pilot randomised controlled trial.
-
Normalization of hematocrit in hemodialysis patients does not affect silent ischemia.
-
Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide.
-
Novel intravenous antithrombins.
-
OUTpatient intravenous LASix Trial in reducing hospitalization for acute decompensated heart failure (OUTLAST).
-
Occurrence and clinical significance of thrombocytopenia in a population undergoing high-risk percutaneous coronary revascularization. Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC) Study Group.
-
Open label study to assess infliximab safety and timing of onset of clinical benefit among patients with rheumatoid arthritis.
-
Open-label extension study following the Late-Onset Treatment Study (LOTS) of alglucosidase alfa.
-
Opioid Sensitivity in Children with and without Obstructive Sleep Apnea.
-
Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: a phase III analgesic trial for hospitalized sickle cell patients with painful episodes.
-
Opioid-volatile anesthetic synergy: a response surface model with remifentanil and sevoflurane as prototypes.
-
Optimizing hospital use of intravenous insulin therapy: improved management of hyperglycemia and error reduction with a new nomogram.
-
Oral high-dose multivitamins and minerals after myocardial infarction: a randomized trial.
-
Oral ondansetron pharmacokinetics: the effect of chemotherapy.
-
Outcomes in mild or rapidly improving stroke not treated with intravenous recombinant tissue-type plasminogen activator: findings from Get With The Guidelines-Stroke.
-
Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC.
-
Overview of randomized trials of intravenous heparin in patients with acute myocardial infarction treated with thrombolytic therapy.
-
Oxidative DNA base modifications in peripheral blood mononuclear cells of patients treated with high-dose infusional doxorubicin.
-
PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled, Phase 2 Study.
-
Paclitaxel by 96-hour continuous infusion in combination with cisplatin: a phase I trial in patients with advanced lung cancer.
-
Paclitaxel for the treatment of progressive or recurrent childhood brain tumors: a pediatric oncology phase II study.
-
Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile.
-
Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis.
-
Patient-controlled analgesia for conscious sedation during endoscopic retrograde cholangiopancreatography: a randomized controlled trial.
-
Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial.
-
Patterns of antihypertensive treatment in patients with acute severe hypertension from a nonneurologic cause: Studying the Treatment of Acute Hypertension (STAT) registry.
-
Pegnivacogin results in near complete FIX inhibition in acute coronary syndrome patients: RADAR pharmacokinetic and pharmacodynamic substudy.
-
Pembrolizumab for Treatment-Refractory Metastatic Castration-Resistant Prostate Cancer: Multicohort, Open-Label Phase II KEYNOTE-199 Study.
-
Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.
-
Pericardial effusion after intravenous recombinant tissue-type plasminogen activator for acute myocardial infarction.
-
Perioperative Antibiotic Prophylaxis in Total Joint Arthroplasty: A Single Dose Is as Effective as Multiple Doses.
-
Perioperative crystalloid and colloid fluid management in children: where are we and how did we get here?
-
Perioperative pharmacokinetics of methadone in adolescents.
-
Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: a randomized controlled trial.
-
Pharmacokinetic and phase I evaluation of carboplatin in dogs.
-
Pharmacokinetic and tolerance evaluation of actisomide, a new antiarrhythmic agent, in healthy volunteers.
-
Pharmacokinetic model-driven infusion of fentanyl: assessment of accuracy.
-
Pharmacokinetics and biochemical efficacy of pirmagrel, a thromboxane synthase inhibitor, in renal allograft recipients.
-
Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout.
-
Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23-29 wk.
-
Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation.
-
Pharmacokinetics and toxicity of 120-hour continuous-infusion hydroxyurea in patients with advanced solid tumors.
-
Pharmacokinetics of aprotinin in preoperative cardiac surgical patients.
-
Pharmacokinetics of doxorubicin administered i.v. as Myocet (TLC D-99; liposome-encapsulated doxorubicin citrate) compared with conventional doxorubicin when given in combination with cyclophosphamide in patients with metastatic breast cancer.
-
Pharmacokinetics of intravenous milrinone in patients undergoing cardiac surgery.
-
Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection.
-
Pharmacologically directed design of the dose rate and schedule of 2',2'-difluorodeoxycytidine (Gemcitabine) administration in leukemia.
-
Phase 1 study of N(1),N(11)‑diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma.
-
Phase 2, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia.
-
Phase I and pharmacokinetic study of 3'-C-ethynylcytidine (TAS-106), an inhibitor of RNA polymerase I, II and III,in patients with advanced solid malignancies.
-
Phase I clinical and plasma and cellular pharmacological study of topotecan without and with granulocyte colony-stimulating factor.
-
Phase I clinical trial of cisplatin given i.v. with 5-fluorouracil and high-dose folinic acid.
-
Phase I evaluation of diaziquone in childhood cancer. A Pediatric Oncology Group study.
-
Phase I evaluation of prolonged-infusion gemcitabine with fludarabine for relapsed or refractory acute myelogenous leukemia.
-
Phase I evaluation of prolonged-infusion gemcitabine with irinotecan for relapsed or refractory leukemia or lymphoma.
-
Phase I evaluation of prolonged-infusion gemcitabine with mitoxantrone for relapsed or refractory acute leukemia.
-
Phase I evaluation of zidovudine administered to infants exposed at birth to the human immunodeficiency virus.
-
Phase I study of 5-day continuous infusion fluorodeoxyuridine and high-dose folinic acid with oral hydroxyurea.
-
Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies.
-
Phase I study of Datelliptium chloride, hydrochloride given by 24-h continuous intravenous infusion.
-
Phase I study of mitomycin C and menadione in advanced solid tumors.
-
Phase I study of recombinant human endostatin in patients with advanced solid tumors.
-
Phase I trial of carboplatin and infusional cyclosporin in advanced malignancy.
-
Phase I trial of menadiol diphosphate (vitamin K3) in advanced malignancy.
-
Phase I trial of systemic oxaliplatin combination chemotherapy with hepatic arterial infusion in patients with unresectable liver metastases from colorectal cancer.
-
Phase I trial of temozolomide plus O6-benzylguanine for patients with recurrent or progressive malignant glioma.
-
Phase I/II study of preoperative oxaliplatin, fluorouracil, and external-beam radiation therapy in patients with locally advanced rectal cancer: Cancer and Leukemia Group B 89901.
-
Phase I/II study of the P-glycoprotein modulator PSC 833 in patients with acute myeloid leukemia.
-
Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer.
-
Phase II evaluation of high-dose intravenous cisplatin for treatment of adult malignant gliomas recurrent after chloroethylnitrosourea failure.
-
Phase II study of MGI-114 administered intravenously for 5 days every 28 days to patients with metastatic colorectal cancer.
-
Phase II study of carboplatin in children with progressive low-grade gliomas.
-
Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium.
-
Phase II study of didemnin B in advanced colorectal cancer.
-
Phase II study of docetaxel in advanced soft tissue sarcomas.
-
Phase II study of docetaxel in patients with pancreatic cancer previously untreated with cytotoxic chemotherapy.
-
Phase II study of infusional chemotherapy with doxorubicin, vincristine and etoposide plus cyclophosphamide and prednisone (I-CHOPE) in resistant diffuse aggressive non-Hodgkin's lymphoma: CALGB 9255. Cancer and Leukemia Group B.
-
Phase II study of intravenous 6-thioguanine in patients with advanced carcinoma of the pancreas.
-
Phase II study of intravenous 6-thioguanine in patients with advanced gastric carcinoma.
-
Phase II study of intravenous CI-958 in metastatic colorectal adenocarcinoma.
-
Phase II study of intravenous idarubicin in unfavorable non-Hodgkin's lymphoma.
-
Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group.
-
Phase II study of troxacitabine (BCH-4556) in patients with advanced non-small-cell lung cancer.
-
Phase II trial of 9-aminocamptothecin (NSC 603071) administered as a 120-hr continuous infusion weekly for three weeks in metastatic colorectal carcinoma.
-
Phase II trial of 9-aminocamptothecin administered as a 72-hour continuous infusion in metastatic colorectal carcinoma.
-
Phase II trial of cetuximab and carboplatin in relapsed platinum-sensitive ovarian cancer and evaluation of epidermal growth factor receptor expression: a Gynecologic Oncology Group study.
-
Phase II trial of gemcitabine plus irinotecan in patients with esophageal cancer: a Southwest Oncology Group (SWOG) trial.
-
Phase II trial of intravenous CI-980 (NSC 370147) in patients with metastatic colorectal carcinoma. Model for prospective evaluation of neurotoxicity.
-
Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma.
-
Phase II trial of karenitecin in patients with relapsed or refractory non-small cell lung cancer (CALGB 30004).
-
Phase II trial of postoperative adjuvant intraperitoneal cisplatin and fluorouracil and systemic fluorouracil chemotherapy in patients with resected gastric cancer.
-
Phase II trial of weekly dose-dense paclitaxel in extensive-stage small cell lung cancer: cancer and leukemia group B study 39901.
-
Phase II, randomized, multicenter, double-blind, placebo-controlled trial of a polyclonal anti-Staphylococcus aureus capsular polysaccharide immune globulin in treatment of Staphylococcus aureus bacteremia.
-
Phase III open-label randomized study of cytarabine in combination with amonafide L-malate or daunorubicin as induction therapy for patients with secondary acute myeloid leukemia.
-
Phase III randomized trial of doxorubicin + cisplatin versus doxorubicin + 24-h paclitaxel + filgrastim in endometrial carcinoma: a Gynecologic Oncology Group study.
-
Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma.
-
Phase III study of N,N-diethyl-2-[4-(phenylmethyl) phenoxy]ethanamine (BMS-217380-01) combined with doxorubicin versus doxorubicin alone in metastatic/recurrent breast cancer: National Cancer Institute of Canada Clinical Trials Group Study MA.19.
-
Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130.
-
Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer.
-
Phlegmonous gastritis: successful treatment with antibiotics and resolution documented by EUS.
-
Phosphodiesterase-5 inhibitors oppose hyperoxic vasoconstriction and accelerate seizure development in rats exposed to hyperbaric oxygen.
-
Photodynamic treatment in a rabbit model of glaucoma surgery.
-
Physiological responses to catecholamine infusions in type A and type B men.
-
Physiological role for cholecystokinin in reducing postprandial hyperglycemia in humans.
-
Plasma and cerebrospinal fluid pharmacokinetics of ondansetron in humans.
-
Plasminogen acceleration of urokinase thrombolysis.
-
Platelet inhibition to target reperfusion injury trial: Rationale and study design.
-
Platelet inhibition with cangrelor in patients undergoing PCI.
-
Pompe disease in infants: improving the prognosis by newborn screening and early treatment.
-
Population Pharmacokinetic Modeling to Evaluate Standard Magnesium Sulfate Treatments and Alternative Dosing Regimens for Women With Preeclampsia.
-
Population Pharmacokinetics and Exploratory Pharmacodynamics of Lorazepam in Pediatric Status Epilepticus.
-
Population pharmacokinetics of lidocaine administered during and after cardiac surgery.
-
Postnatal alterations in beta-adrenergic receptor binding in rat brain regions after continuous prenatal exposure to propranolol via maternal infusion.
-
Postoperative antibiotic therapy for children with perforated appendicitis: long course of intravenous antibiotics versus early conversion to an oral regimen.
-
Postoperative oxycodone toxicity in a patient with chronic pain and end-stage renal disease.
-
Prediction of enzymatic infarct size in ST-segment elevation myocardial infarction.
-
Predictors of 90-day readmission among patients with acute severe hypertension. The cross-sectional observational Studying the Treatment of Acute hyperTension (STAT) study.
-
Preliminary analysis of a randomized comparison of 5-fluorouracil versus 5-fluorouracil and high-dose continuous-infusion folinic acid in disseminated colorectal cancer.
-
Preliminary experience with intravenous P2Y12 platelet receptor inhibition as an adjunct to reduced-dose alteplase during acute myocardial infarction: results of the Safety, Tolerability and Effect on Patency in Acute Myocardial Infarction (STEP-AMI) angiographic trial.
-
Prenatal nicotine exposure and cognitive performance in rats.
-
Primary Immune Deficiency: Patients' Preferences for Replacement Immunoglobulin Therapy.
-
Prognosis on chronic dobutamine or milrinone infusions for stage D heart failure.
-
Prognostic importance of concomitant heparin with eptifibatide in acute coronary syndromes. PURSUIT Investigators. Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy.
-
Prolonged ketamine infusion modulates limbic connectivity and induces sustained remission of treatment-resistant depression.
-
Prophylactic intravenous amphotericin B in neutropenic autologous bone marrow transplant recipients.
-
Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators.
-
Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy.
-
Prostaglandin E1-Induced Periostitis and Reversibility with Discontinuation.
-
Proteolytic degradation of von Willebrand factor after DDAVP administration in normal individuals.
-
QTc interval prolongation associated with intravenous methadone.
-
Quality-of-life improvements in cutaneous T-cell lymphoma patients treated with denileukin diftitox (ONTAK).
-
Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET.
-
Quantification of nicotinic acetylcholine receptors in the human brain with PET: bolus plus infusion administration of 2-[18F]F-A85380.
-
Race, borderline hypertension, and hemodynamic responses to behavioral stress before and after beta-adrenergic blockade.
-
Randomised clinical trial: a phase 1, dose-ranging study of the anti-matrix metalloproteinase-9 monoclonal antibody GS-5745 versus placebo for ulcerative colitis.
-
Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff.
-
Randomized Evaluation of Heart Failure With Preserved Ejection Fraction Patients With Acute Heart Failure and Dopamine: The ROPA-DOP Trial.
-
Randomized Population Pharmacokinetic Analysis and Safety of Intravenous Acetaminophen for Acute Postoperative Pain in Neonates and Infants.
-
Randomized Trial of Intravenous Versus Intraperitoneal Chemotherapy Plus Bevacizumab in Advanced Ovarian Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study.
-
Randomized double-blind trial of midazolam/placebo and midazolam/fentanyl for sedation and analgesia in lower-extremity angiography.
-
Randomized phase II comparison of dose-intense gemcitabine: thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma.
-
Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer: CALGB 89904.
-
Randomized phase II study of neoadjuvant combined-modality chemoradiation for distal rectal cancer: Radiation Therapy Oncology Group Trial 0012.
-
Randomized study of continuous infusion fluorouracil versus fluorouracil plus cisplatin in patients with metastatic colorectal cancer.
-
Randomized trial of prostacyclin infusion in acute myocardial infarction.
-
Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease.
-
Randomized, double-blind trial of cefonicid and nafcillin in the treatment of skin and skin structure infections.
-
Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome.
-
Ranitidine improves lymphocyte function after severe head injury: results of a randomized, double-blind study.
-
Rapid infusion of Sandoglobulin in patients with primary humoral immunodeficiency.
-
Rationale and design of Apo-I Event Reduction in Ischemic Syndromes I (AEGIS-I): A phase 2b, randomized, placebo-controlled, dose-ranging trial to investigate the safety and tolerability of CSL112, a reconstituted, infusible, human apoA-I, after acute myocardial infarction.
-
Rationale and design of the allogeneiC human mesenchymal stem cells (hMSC) in patients with aging fRAilTy via intravenoUS delivery (CRATUS) study: A phase I/II, randomized, blinded and placebo controlled trial to evaluate the safety and potential efficacy of allogeneic human mesenchymal stem cell infusion in patients with aging frailty.
-
Real-time three-dimensional echocardiography to construct clinically ready, load-independent indices of myocardial contractile performance.
-
Rebound increase in thrombin generation and activity after cessation of intravenous heparin in patients with acute coronary syndromes.
-
Recovery of vision in a 47-year-old man with fulminant giant cell arteritis.
-
Rectal tissue and vaginal tissue from intravenous VRC01 recipients show protection against ex vivo HIV-1 challenge.
-
Reduced GABA synthesis in pyridoxine-dependent seizures.
-
Refractory Status Epilepticus in Children: Intention to Treat With Continuous Infusions of Midazolam and Pentobarbital.
-
Refractory adenovirus infection after simultaneous kidney-pancreas transplantation: successful treatment with intravenous ribavirin and pooled human intravenous immunoglobulin.
-
Refractory metastatic breast cancer: salvage therapy with fluorouracil and high-dose continuous infusion leucovorin calcium.
-
Regulation of islet hormone release and gastric emptying by endogenous glucagon-like peptide 1 after glucose ingestion.
-
Reinforcing effects of nicotine and non-nicotine components of cigarette smoke.
-
Relapse in Guillain-Barré syndrome after treatment with human immune globulin.
-
Relation of impaired Thrombolysis In Myocardial Infarction myocardial perfusion grades to residual thrombus following the restoration of epicardial patency in ST-elevation myocardial infarction.
-
Relationship of incorrect dosing of fibrinolytic therapy and clinical outcomes.
-
Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.
-
Renal Dysfunction and In-Hospital Outcomes in Patients With Acute Ischemic Stroke After Intravenous Thrombolytic Therapy.
-
Renal cell carcinoma treated with continuous-infusion interleukin-2 with ex vivo-activated killer cells.
-
Repeated ketamine infusions for antidepressant-resistant PTSD: Methods of a multicenter, randomized, placebo-controlled clinical trial.
-
Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial.
-
Reply: Efficacy of Subcutaneous vs. Intravenous Administration of Furosemide in Patients With Worsening Heart Failure: The Devil Is in the Details.
-
Resectable gastric carcinoma. An evaluation of preoperative and postoperative chemotherapy.
-
Respiratory effects of pressor and depressor agents in conscious rats.
-
Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor.
-
Results of high dose intravenous urokinase for acute myocardial infarction.
-
Results of the first clinical study of adjunctive CAldaret (MCC-135) in patients undergoing primary percutaneous coronary intervention for ST-Elevation Myocardial Infarction: the randomized multicentre CASTEMI study.
-
Rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis: the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. The Studies of Ocular Complications of AIDS (SOCA) Research Group in Collaboration with the AIDS Clinical Trials Group (ACTG).
-
Risks of intracranial hemorrhage among patients with acute ischemic stroke receiving warfarin and treated with intravenous tissue plasminogen activator.
-
Role of guanylate cyclase modulators in decompensated heart failure.
-
Safety and Efficacy of Remimazolam Compared With Placebo and Midazolam for Moderate Sedation During Bronchoscopy.
-
Safety and Outcomes of Intravenous tPA in Acute Ischemic Stroke Patients With Prior Stroke Within 3 Months: Findings From Get With The Guidelines-Stroke.
-
Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.
-
Safety and efficacy of quinupristin/dalfopristin for treatment of invasive Gram-positive infections in pediatric patients.
-
Safety and efficacy of tirofiban in stent-assisted coil embolization of intracranial aneurysms.
-
Safety and pharmacokinetics of multiple dose myo-inositol in preterm infants.
-
Safety and tolerance of intermittent intravenous and oral zidovudine therapy in human immunodeficiency virus-infected pediatric patients. Pediatric Zidovudine Phase I Study Group.
-
Safety profile of L-arginine infusion in moderately severe falciparum malaria.
-
Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive-stage small-cell lung cancer: a randomized phase III study of the Cancer and Leukemia Group B.
-
Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2.
-
Sequential changes in atrial pressures, dimensions, and plasma atrial natriuretic factor concentrations during volume loading in hemodynamically normal human subjects.
-
Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia.
-
Serelaxin in addition to standard therapy in acute heart failure: rationale and design of the RELAX-AHF-2 study.
-
Short-term adolescent nicotine exposure in rats elicits immediate and delayed deficits in T-lymphocyte function: critical periods, patterns of exposure, dose thresholds.
-
Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial.
-
Single infusion of zoledronate in Paget's disease of bone: a placebo-controlled, dose-ranging study.
-
Single-dose oritavancin in the treatment of acute bacterial skin infections.
-
Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults.
-
Site enrollment rate, outcomes, and study drug effects in a multicenter trial. Results from RELAX-AHF.
-
Successful use of chronic epoprostenol as a bridge to liver transplantation in severe portopulmonary hypertension.
-
Suppository administration of chemotherapeutic drugs with concomitant radiation for rectal cancer.
-
Survival of African-American and Caucasian men after sipuleucel-T immunotherapy: outcomes from the PROCEED registry.
-
Symbiotic relationship of IV-tPA and mechanical thrombectomy in a case of acute tandem ICA-MCA occlusion.
-
Systemic doxorubicin and intraarterial cisplatin preoperative chemotherapy plus postoperative adjuvant chemotherapy in patients with osteosarcoma.
-
Target: Stroke Was Associated With Faster Intravenous Thrombolysis and Improved One-Year Outcomes for Acute Ischemic Stroke in Medicare Beneficiaries.
-
Taxol-induced soft-tissue injury secondary to extravasation: characterization by histopathology and clinical course.
-
Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4).
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Thallium-201 myocardial imaging in patients with coronary artery disease: comparison of intravenous adenosine and oral dipyridamole.
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The Line Snuggler: A Central Line Bundling Innovation Evaluated in a High-Risk Pediatric Population.
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The Role of Adjunctive Therapies in the Management of Invasive Sino-Orbital Infection.
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The clinical and prognostic importance of positive blood cultures in adults.
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The corticotropin-releasing hormone test in patients with posttraumatic stress disorder.
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The effect of corticosteroids for acute optic neuritis on the subsequent development of multiple sclerosis. The Optic Neuritis Study Group.
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The effect of ionised magnesium on coagulation using thromboelastography.
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The effect of left-sided versus right-sided contrast infusion on attenuation of the main pulmonary artery when performing computed tomography angiograms of the chest.
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The effect of milrinone on hemodynamics and left ventricular function after emergence from cardiopulmonary bypass.
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The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone.
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The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle.
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The effects of mannitol on cerebral edema after large hemispheric cerebral infarct.
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The efficacy and resource utilization of remifentanil and fentanyl in fast-track coronary artery bypass graft surgery: a prospective randomized, double-blinded controlled, multi-center trial.
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The impact of Filgrastim schedule variation on hematopoietic recovery post-chemotherapy.
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The impact of docetaxel, estramustine, and low dose hydrocortisone on the quality of life of men with hormone refractory prostate cancer and their partners: a feasibility study.
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The impact of intravenous fluid administration on complication rates in bowel surgery within an enhanced recovery protocol: a randomized controlled trial.
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The lack of science behind the standard of care.
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The nitric oxide donor S-nitroso-N-acetylpenicillamine (SNAP) increases free radical generation and degrades left ventricular function after myocardial ischemia-reperfusion.
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The peripartum management of a patient with glutaric aciduria type 1.
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The prepuce as a donor site for reconstruction of an extravasation injury to the foot in a newborn.
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The role of intravenous acetaminophen in multimodal pain protocols for perioperative orthopedic patients.
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The safe administration of intravenous contrast material for urologists and radiologists.
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The use of bovine hemoglobin glutamer-250 (Hemopure) in surgical patients: results of a multicenter, randomized, single-blinded trial.
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The use of intravenous immune globulin in immunodeficiency diseases.
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The use of vasoactive agents via peripheral intravenous access during transport of critically III infants and children.
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The virologic, immunologic, and clinical effects of interleukin 2 with potent antiretroviral therapy in patients with moderately advanced human immunodeficiency virus infection: a randomized controlled clinical trial--AIDS Clinical Trials Group 328.
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Thrombolysis and adjunctive therapy in acute myocardial infarction: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
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Time to treatment and the impact of a physician on prehospital management of acute ST elevation myocardial infarction: insights from the ASSENT-3 PLUS trial.
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Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke.
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Timing of and risk factors for myocardial ischemic events after percutaneous coronary intervention (IMPACT-II). Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis.
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Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.
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Tissue plasminogen activator for the treatment of acute pulmonary embolism. A collaborative study by the PIOPED Investigators.
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Too much of a good thing? Tracing the history of the propofol infusion syndrome.
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Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm.
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Treatment of children symptomatic with human immunodeficiency virus infection.
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Treatment of dural sinus thrombosis by urokinase infusion.
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Treatment of established deep vein thrombosis: a review of the therapeutic armamentarium.
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Treatment of hyperkalaemia using intravenous and nebulised salbutamol.
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Treatment of postoperative hypertension after coronary artery bypass surgery. Double-blind comparison of intravenous isradipine and sodium nitroprusside.
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Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen.
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Ultrafiltration in decompensated heart failure with cardiorenal syndrome.
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Unfractionated heparin dosing and risk of major bleeding in non-ST-segment elevation acute coronary syndromes.
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Upper Extremity Peripheral Intravenous Line Infiltration With Concomitant Loss of Pulses Treated With Lipoaspiration: A Case Report.
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Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis.
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Use of Strategies to Improve Door-to-Needle Times With Tissue-Type Plasminogen Activator in Acute Ischemic Stroke in Clinical Practice: Findings from Target: Stroke.
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Use of nitroglycerin by bolus prevents intensive care unit admission in patients with acute hypertensive heart failure.
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Using negative control outcomes to assess the comparability of treatment groups among women with osteoporosis in the United States.
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Utilization of intravenous tissue plasminogen activator for ischemic stroke: are there sex differences?
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Vancomycin-resistant enterococci: risk related to the use of intravenous vancomycin in a university hospital.
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Vascular access site complications after percutaneous coronary intervention with abciximab in the Evaluation of c7E3 for the Prevention of Ischemic Complications (EPIC) trial.
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Ventilatory effects of angiotensin and vasopressin in conscious rats.
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Verapamil prolongs atrial fibrillation by evoking an intense sympathetic neurohumoral effect.
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Visual improvement despite radiologically stable disease after treatment with carboplatin in children with progressive low-grade optic/thalamic gliomas.
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Volume-mediated pulmonary responses in liver transplant candidates.
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Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever.
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Who merits a neck dissection after definitive chemoradiotherapy for N2-N3 squamous cell head and neck cancer?
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Zoledronic Acid in Reducing Clinical Fracture and Mortality after Hip Fracture.
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Zoledronic acid preserves bone mineral density in premenopausal women who develop ovarian failure due to adjuvant chemotherapy: final results from CALGB trial 79809.
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[Prostaglandin E1 for prevention of contrast medium-induced kidney dysfunction].
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[Three subanaesthetic dose ketamines mixed with butorphanol in the postoperative continuous intravenous analgesia].
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Keywords of People
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Alexander, John Hunter Peel,
Professor of Medicine,
Medicine, Cardiology
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Barker, Piers Christopher Andrew,
Professor of Pediatrics,
Pediatrics, Cardiology
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Esclamado, Ramon Mitra,
Professor Emeritus of Head and Neck Surgery & Communication Sciences,
Head and Neck Surgery & Communication Sciences
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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Muir, Kelly Walton,
Associate Professor of Ophthalmology,
Ophthalmology, Glaucoma
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O'Connor, Christopher Michael,
Richard Sean Stack, M.D. Distinguished Professor,
Medicine, Clinical Pharmacology
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering