Injections, Intraperitoneal

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  Subject Areas on Research

  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces organ- specific differential gene expression in male Japanese medaka (Oryzias latipes). 
  • A new synthetic protectin D1 analog 3-oxa-PD1n-3 DPA reduces neuropathic pain and chronic itch in mice. 
  • A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis. 
  • A prospective clinical and pathological examination of injection site reactions with the HIV-1 fusion inhibitor enfuvirtide. 
  • A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection. 
  • A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphotericin B and enhances adaptive immunity in murine cutaneous leishmaniasis. 
  • Adaptation after small bowel resection is attenuated by sialoadenectomy: the role for endogenous epidermal growth factor. 
  • Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels. 
  • Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature. 
  • An in vivo platform for translational drug development in pancreatic cancer. 
  • Anti-hypotensive treatment and endothelin blockade synergistically antagonize exercise fatigue in rats under simulated high altitude. 
  • Anticonvulsant action and long-term effects of gabapentin in the immature brain. 
  • Anxiolytic effects of acute morphine can be modulated by nitric oxide systems. 
  • Assessment of the protective effect of amifostine on radiation-induced pulmonary toxicity. 
  • Attenuation of the effect of punishment by thyrotropin-releasing hormone: comparisons with chlordiazepoxide. 
  • Biodistribution of O6-benzylguanine and its effectiveness against human brain tumor xenografts when given in polyethylene glycol or cremophor-EL. 
  • Blocking [211At]astatide accumulation in normal tissues: preliminary evaluation of seven potential compounds. 
  • Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice. 
  • Busulfan therapy of central nervous system xenografts in athymic mice. 
  • COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat. 
  • Central infusion of glucagon-like peptide-1-(7-36) amide (GLP-1) receptor antagonist attenuates lithium chloride-induced c-Fos induction in rat brainstem. 
  • Characterization and solubilization of pyrrole-imidazole polyamide aggregates. 
  • Cyclocreatine in cancer chemotherapy. 
  • Developmental differences in the acquisition of tolerance to ethanol. 
  • Differences in the central anorectic effects of glucagon-like peptide-1 and exendin-4 in rats. 
  • Differential effects of ethanol on memory in adolescent and adult rats. 
  • Direct measurement of fast axonal organelle transport in the sciatic nerve of rats treated with acrylamide. 
  • Diurnal variations in the toxicity and tissue levels of spermidine in mice. 
  • Dynamic gene expression changes precede dioxin-induced liver pathogenesis in medaka fish. 
  • Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration. 
  • Effect of pregabalin on cerebral outcome after cardiopulmonary bypass with deep hypothermic circulatory arrest in rats. 
  • Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats. 
  • Effects of nimodipine on the behavioral sequalae of experimental status epilepticus in prepubescent rats. 
  • Endotoxin-induced uveitis in the rat: observations on altered vascular permeability, clinical findings, and histology. 
  • Enhanced type 1 immunity after secondary viral challenge in mice primed as neonates. 
  • Epidermal growth factor augments adaptation following small bowel resection: optimal dosage, route, and timing of administration. 
  • Evidence for metabolism of fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A), a sevoflurane degradation product, by cysteine conjugate beta-lyase. 
  • Exogenous pyruvate prevents stress-evoked suppression of mitogen-stimulated proliferation. 
  • Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. 
  • Fibrous glass and cancer. 
  • Functional effects of lymphotoxin on crushed peripheral nerve. 
  • GBR12909 stimulates hypothalamo-pituitary-adrenal activity by inhibition of uptake at hypothalamic dopamine neurons. 
  • Genetic control of peripheral leukocyte response to endotoxin in mice. 
  • Hippocampal programmed cell death after status epilepticus: evidence for NMDA-receptor and ceramide-mediated mechanisms. 
  • INTRAPERITONEAL DEXTROSE ADMINISTRATION AS AN ALTERNATIVE EMERGENCY TREATMENT FOR HYPOGLYCEMIC YEARLING CALIFORNIA SEA LIONS (ZALOPHUS CALIFORNIANUS). 
  • In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus. 
  • In vivo modulation of macrophage tumoricidal activity: enhanced tumor cell killing by peritoneal macrophages from mice given injections of sodium periodate. 
  • Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats. 
  • Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program. 
  • Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin. 
  • Intracisternal injection of apolipoprotein A-IV inhibits gastric secretion in pylorus-ligated conscious rats. 
  • Intracisternal injection of pancreatic polypeptide stimulates gastric emptying in rats. 
  • Intranasal vaccination with the recombinant Listeria monocytogenes ΔactA prfA* mutant elicits robust systemic and pulmonary cellular responses and secretory mucosal IgA. 
  • Intraperitoneal chromic phosphate P 32 suspension therapy of malignant peritoneal cytology in endometrial carcinoma. 
  • Intraperitoneal fluid neopterin, nitrate, and tryptophan after regional administration of interleukin-12. 
  • Intravascular coagulation--a source of possible error in carbon-clearance determinations. 
  • Is Intraperitoneal Chemotherapy Dead? 
  • Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy. 
  • Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. 
  • Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. 
  • Localization of functionally different guinea-pig spleen cells in albumin gradients. 
  • Long-term effects of excitatory amino acid antagonists NBQX and MK-801 on the developing brain. 
  • Long-term neuroprotection by benzodiazepine full versus partial agonists after transient cerebral ischemia in the gerbil [corrected]. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity. 
  • Metformin prevents tobacco carcinogen--induced lung tumorigenesis. 
  • Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. 
  • Mitochondrial DNA damage as a peripheral biomarker for mitochondrial toxin exposure in rats. 
  • Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. 
  • Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation. 
  • Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease. 
  • Neurotoxicity of ethyl methacrylate in rats. 
  • Nicotine-alcohol interactions and cognitive function in rats. 
  • Organ distribution of Corynebacterium parvum labeled with iodine-125. 
  • PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. 
  • Peritonitis due to Neisseria mucosa in an adolescent receiving peritoneal dialysis. 
  • Pharmacokinetics and toxicity of intraperitoneal cisplatin combined with regional hyperthermia. 
  • Pharmacokinetics of intraperitoneal, intravenous, and subcutaneous recombinant human erythropoietin in patients on continuous ambulatory peritoneal dialysis. 
  • Phase I study of intraperitoneal recombinant human interleukin 12 in patients with Müllerian carcinoma, gastrointestinal primary malignancies, and mesothelioma. 
  • Phase I trial of intraperitoneal iododeoxyuridine with and without intravenous high-dose folinic acid in the treatment of advanced malignancies primarily confined to the peritoneal cavity: flow cytometric and pharmacokinetic analysis. 
  • Phenylmethylsulfonyl fluoride protects rats from Mipafox-induced delayed neuropathy. 
  • Protective response of the Ah receptor to ANIT-induced biliary epithelial cell toxicity in see-through medaka. 
  • Pulmonary toxicity after intraperitoneal mitomycin C: a case report of a rare complication of HIPEC. 
  • Purification and some properties of Cd-binding protein from rat liver. 
  • Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors. 
  • Repetitive intraperitoneal caspase-3 inhibitor and anesthesia reduces neuronal damage. 
  • Role of 14-3-3-mediated p38 mitogen-activated protein kinase inhibition in cardiac myocyte survival. 
  • Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors. 
  • Sex differences in the effects of delta9-tetrahydrocannabinol on spatial learning in adolescent and adult rats. 
  • Simian virus 40-induced retinopathy in the rat. 
  • Strain-specific spontaneous and NNK-mediated tumorigenesis in Pten+/- mice. 
  • Studies on cellular autophagocytosis. A histochemical study on sequential alterations of mitochondria in the glucagon-induced autophagic vacuoles of rat liver. 
  • Studies on cellular autophagocytosis. Cyclic AMP- and dibutyryl cyclic AMP-stimulated autophagy in rat liver. 
  • Suppression of alcohol intake after administration of the Chinese herbal medicine, NPI-028, and its derivatives. 
  • Tamoxifen Improves Glucose Tolerance in a Delivery-, Sex-, and Strain-Dependent Manner in Mice. 
  • Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance. 
  • The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice. 
  • The acute toxicity of drugs acting at cholinoceptive sites and twenty-four hour rhythms in brain acetylcholine. 
  • The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression. 
  • The distribution of cocaine in mice differs by age and strain. 
  • The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness. 
  • The efficacy of the appetite suppressant, diethylpropion, is dependent on both when it is given (day vs. night) and under conditions of high fat dietary restriction. 
  • The impact of dose rate on the neurotoxicity of acrylamide: the interaction of administered dose, target tissue concentrations, tissue damage, and functional effects. 
  • The pediatric preclinical testing program: description of models and early testing results. 
  • Therapeutic activity of the topoisomerase I inhibitor J-107088 [6-N-(1-hydroxymethyla-2-hydroxyl) ethylamino-12,13-dihydro-13-(beta-D-glucopyranosyl) -5H-indolo[2,3-a]-pyrrolo[3,4-c]-carbazole-5,7(6H)-dione]] against pediatric and adult central nervous system tumor xenografts. 
  • Thyrotropin-releasing hormone analog TA-0910 reduces voluntary alcohol intake of P rats subchronically in a limited scheduled access paradigm. 
  • Transplantation of rat insulinoma allografts with cyclosporin A. 
  • Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD. 
  • Treatment of intracranial alphavirus infections in mice by a combination of specific antibodies and an interferon inducer. 
  • Triphenyl phosphite-induced impairment of spatial alternation learning. 
  • Tumor resistance in rats immunized to fetal tissues. 
  • Use of poly-l-aspartic acid to inhibit aminoglycoside cochlear ototoxicity. 
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  Keywords of People

  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Schwartz-Bloom, Rochelle D., Professor Emeritus of Pharmacology & Cancer Biology, Duke Science & Society