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Subject Areas on Research
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A reappraisal of the results of stopping therapy in childhood leukemia.
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Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep.
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Activity of intrathecal 4-hydroperoxycyclophosphamide in a nude rat model of human neoplastic meningitis.
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Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type.
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Advantages of the combined spinal epidural (CSE) technique.
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An unusual presentation of chronic myelogenous leukemia: a review of isolated central nervous system relapse.
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Analysis of glycosaminoglycans in cerebrospinal fluid from patients with mucopolysaccharidoses by isotope-dilution ultra-performance liquid chromatography-tandem mass spectrometry.
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Antimetabolite therapy for lesser-risk B-lineage acute lymphoblastic leukemia of childhood: a report from Children's Oncology Group Study P9201.
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Apolipoprotein A-IV acts centrally in the brain to reduce the severity of gastric ulceration in the rat.
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Behavioural testing and histological assessments of rabbit spinal cord following intrathecal administration of ondansetron.
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CT-guided cervical transforaminal steroid injections: where should the needle tip be located?
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Chronic CSF leak into the peritoneal cavity shown by radionuclide cisternography. Successful treatment with an epidural blood patch.
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Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity.
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Comparison of Tc99m-DTPA and indium-111 DTPA studies of baclofen pump function.
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Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice.
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Cytokinetically based induction chemotherapy and splenectomy for childhood acute nonlymphocytic leukemia.
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Determination of the effective therapeutic dose of intrathecal sufentanil for extracorporeal shock wave lithotripsy.
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Dexamethasone for the prophylaxis of postoperative nausea and vomiting associated with neuraxial morphine administration: a systematic review and meta-analysis.
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Different patterns of relapse associated with three intensive treatment regimens for pediatric E-rosette positive T-cell leukemia: a Pediatric Oncology Group study.
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ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity.
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Effect of administration of high dose intrathecal clonidine or morphine prior to sciatic nerve section on c-Fos expression in rat lumbar spinal cord.
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Effects of cranial radiation in children with high risk T cell acute lymphoblastic leukemia: a Pediatric Oncology Group report.
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Immunoreactivity, pharmacokinetics and bone marrow dosimetry of intrathecal radioimmunoconjugates.
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In vivo diffusion-weighted magnetic resonance microscopy of rat spinal cord: effect of ischemia and intrathecal hyperbaric 5% lidocaine.
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Inadvertent Intrafacet Injection during Lumbar Interlaminar Epidural Steroid Injection: A Comparison of CT Fluoroscopic and Conventional Fluoroscopic Guidance.
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Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation.
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Intradiscal injection of simvastatin results in radiologic, histologic, and genetic evidence of disc regeneration in a rat model of degenerative disc disease.
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Intramedullary contrast injection in the setting of a split spinal cord.
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Intrathecal administration of 131I radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.
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Intrathecal administration of a novel apoE-derived therapeutic peptide improves outcome following perinatal hypoxic-ischemic injury.
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Intrathecal administration of antisense oligonucleotide against p38α but not p38β MAP kinase isoform reduces neuropathic and postoperative pain and TLR4-induced pain in male mice.
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Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model.
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Intrathecal busulfan treatment of human neoplastic meningitis in athymic nude rats.
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Intrathecal endotoxin: Intrathecal endotoxin: the role of the central nervous system in septic shock.
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Intrathecal enzyme replacement for cognitive decline in mucopolysaccharidosis type I, a randomized, open-label, controlled pilot study.
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Intrathecal ketorolac tromethamine produces analgesia after chronic constriction injury of sciatic nerve in rat.
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Intrathecal melphalan therapy of human neoplastic meningitis in athymic nude rats.
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Intrathecal morphine for analgesia after postpartum bilateral tubal ligation.
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Intrathecal morphine for postpartum bilateral tubal ligation.
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Intrathecal morphine suppresses immune function in rats with inflammatory-induced pain.
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Intrathecal sufentanil for extracorporeal shock wave lithotripsy provides earlier discharge of the outpatient than intrathecal lidocaine.
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Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection.
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Low-dose naloxone infusion for the treatment of intractable nausea and vomiting after intrathecal morphine in a parturient.
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Maculopathy as a complication of blood-brain barrier disruption in patients with central nervous system lymphoma.
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Meningitis due to Mycobacterium bovis BCG--reactivation or accidental intrathecal inoculation?
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Modified LSA2-L2 treatment in 53 children with E-rosette-positive T-cell leukemia: results and prognostic factors (a Pediatric Oncology Group Study).
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Mouse spinal cord compression injury is ameliorated by intrathecal cationic manganese(III) porphyrin catalytic antioxidant therapy.
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Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model.
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Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism.
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Novel intrathecal and subcutaneous catheter delivery systems in the mouse.
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Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy.
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Oxidative changes in cerebral spinal fluid phosphatidylcholine during treatment for acute lymphoblastic leukemia.
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Persistent Catechol-O-methyltransferase-dependent Pain Is Initiated by Peripheral β-Adrenergic Receptors.
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Persistent pain associated with long-term intrathecal morphine administration.
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Phase I clinical trial of mafosfamide in infants and children aged 3 years or younger with newly diagnosed embryonal tumors: a pediatric brain tumor consortium study (PBTC-001).
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Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004).
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Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion.
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Pilot study of systemic and intrathecal mafosfamide followed by conformal radiation for infants with intracranial central nervous system tumors: a pediatric brain tumor consortium study (PBTC-001).
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Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines.
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Prognostic factors that increase the risk for reduced white matter volumes and deficits in attention and learning for survivors of childhood cancers.
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Pupillary response in patients receiving intrathecal sufentanil.
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Radiation dose exposure for lumbar spine epidural steroid injections: a comparison of conventional fluoroscopy data and CT fluoroscopy techniques.
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Re: Toxicity of intrathecal melphalan.
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Reducing Patient Radiation Exposure From CT Fluoroscopy-Guided Lumbar Spine Pain Injections by Targeting the Planning CT.
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Refractory status epilepticus after inadvertent intrathecal injection of tranexamic acid treated by magnesium sulfate.
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Regional treatment of epidermal growth factor receptor vIII-expressing neoplastic meningitis with a single-chain immunotoxin, MR-1.
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Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors.
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Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury.
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Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions.
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Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty.
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Second central nervous system prophylaxis in children with acute lymphoblastic leukemia who relapse after elective cessation of therapy.
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Seesaw nystagmus following whole brain irradiation and intrathecal methotrexate.
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Self-extraction of intrathecal pump opioid.
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Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea, and vomiting in women undergoing cesarean delivery with intrathecal morphine: a systematic review and meta-analysis.
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Short small-interfering RNAs produce interferon-α-mediated analgesia.
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Small-dose intrathecal lidocaine versus ropivacaine for anorectal surgery in an ambulatory setting.
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Spinal anesthesia for orthopedic surgery: a detailed video assessment of quality.
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Spinal cord neural anatomy in rats examined by in vivo magnetic resonance microscopy.
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Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1.
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Sprouting of substance P-expressing primary afferent central terminals and spinal micturition reflex NK1 receptor dependence after spinal cord injury.
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Standardization of health care provider competencies for intrathecal access procedures.
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Targeted therapy for glioblastoma multiforme neoplastic meningitis with intrathecal delivery of an oncolytic recombinant poliovirus.
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Tetanus neonatorum: clinico-epidemiological profile.
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The effect of intrathecal neuropeptide Y on the flexor reflex in rats after carrageenan-induced inflammation.
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The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat.
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The use of an intrathecal pump to manage intractable cancer pain in a pediatric patient: a case report.
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The use of nalmefene for intrathecal opioid-associated nausea in postpartum patients.
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Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury.
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Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.
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Tissue distribution and radiation dosimetry of astatine-211-labeled chimeric 81C6, an alpha-particle-emitting immunoconjugate.
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Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1β and ERK signaling in the spinal cord of mice.
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Transversus abdominis plane block for analgesia after Cesarean delivery: a systematic review and meta-analysis.
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Treatment of HER2-positive breast carcinomatous meningitis with intrathecal administration of alpha-particle-emitting (211)At-labeled trastuzumab.
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Treatment of neoplastic meningitis with intrathecal 9-nitro-camptothecin.
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Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess.
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Use of neostigmine in the management of acute postoperative pain and labour pain: a review.
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[Analgesic effect of intrathecal injection of Herpes simplex virus type I amplicon vector-mediated human preproenkephalin gene on chronic neuropathic pain: experiment with rats].
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[Effect of intrathecal katemine on the expression of nNOS in spinal dorsal horn in rats with formalin pain].
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[Effect of intrathecal pumping morphine on immunological function in rats with formalin pain].
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[Effect of intrathecal pumping tramadol on the immune function in rats with formalin pain].
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[Intrathecal administration of HSV-I amplicon vector-mediated HPPE gene therapy of nocicepion in rats with formalin pain].
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p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.
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β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain.
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Keywords of People
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Gunn, Michael Dee,
Professor of Medicine,
Immunology
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Siriwetchadarak, Rapipen,
Assistant Professor of Neurosurgery,
Neurosurgery
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Warner, David Samuel,
Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine,
Neurobiology
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Wiggins, Walter,
Assistant Professor of Radiology,
Radiology, Neuroradiology