Insecticides

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  Subject Areas on Research

  • A Voucher System To Speed Review Could Promote A New Generation Of Insecticides To Fight Vector-Borne Diseases. 
  • A randomized longitudinal factorial design to assess malaria vector control and disease management interventions in rural Tanzania. 
  • A research agenda to underpin malaria eradication. 
  • A solid phase extraction reversed-phase HPLC method for the simultaneous determination of methoprene, permethrin and selected metabolites in rat plasma and urine. 
  • Absorption, distribution, metabolism and excretion of daily oral doses of [14C]methyl parathion in hens. 
  • Alteration in cytoskeletal protein levels in sciatic nerve on post-treatment of diisopropyl phosphorofluoridate (DFP)-treated hen with phenylmethylsulfonyl fluoride. 
  • Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure. 
  • Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells. 
  • An examination of the proconvulsant actions of pyrethroid insecticides using pentylenetetrazol and amygdala kindling seizure models. 
  • An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae. 
  • Anti-Müllerian hormone and lifestyle, reproductive, and environmental factors among women in rural South Africa. 
  • Bayesian isotonic regression and trend analysis. 
  • Bayesian multivariate logistic regression. 
  • Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation. 
  • Benzo[a]pyrene impairs neurodifferentiation in PC12 cells. 
  • Binding of pyridostigmine bromide, N,N-diethyl-m-toluamide and permethrin, alone and in combinations, to human serum albumin. 
  • Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade. 
  • Chemical and pharmacokinetic considerations in structure-activity relationships: panel discussion. 
  • Chick microsomal oxidases. Isolation, properties, and stimulation by embryonic exposure to 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane. 
  • Chlordanes in the indoor and outdoor air of three U.S. cities. 
  • Chlorpyrifos accumulation patterns for child-accessible surfaces and objects and urinary metabolite excretion by children for 2 weeks after crack-and-crevice application. 
  • Chlorpyrifos developmental neurotoxicity: interaction with glucocorticoids in PC12 cells. 
  • Chlorpyrifos exposure of developing zebrafish: effects on survival and long-term effects on response latency and spatial discrimination. 
  • Chlorpyrifos oxon interacts with the mammalian multidrug resistance protein, P-glycoprotein. 
  • Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes. 
  • Chlorpyrifos targets developing glia: effects on glial fibrillary acidic protein. 
  • Chronology of sodium channel mutations associated with pyrethroid resistance in Aedes aegypti. 
  • Co-exposure to pyridostigmine bromide, DEET, and/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity. 
  • Combined exposure to DEET (N,N-diethyl-m-toluamide) and permethrin-induced release of rat brain mitochondrial cytochrome c. 
  • Combined exposure to DEET (N,N-diethyl-m-toluamide) and permethrin: pharmacokinetics and toxicological effects. 
  • Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity. 
  • Comparative field evaluation of combinations of long-lasting insecticide treated nets and indoor residual spraying, relative to either method alone, for malaria prevention in an area where the main vector is Anopheles arabiensis. 
  • Comparative toxicities of selected compounds to nauplii of Balanus amphitrite amphitrite Darwin and Artemia sp. 
  • Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions. 
  • Contact toxicity of permethrin-impregnated fabric to Hyalomma anatolicum excavatum (Acari: Ixodidae): effects of laundering and exposure and recovery times. 
  • Contamination of rural surface and ground water by endosulfan in farming areas of the Western Cape, South Africa. 
  • Cost of microbial larviciding for malaria control in rural Tanzania. 
  • Coumaphos: delayed neurotoxic effect following dermal administration in hens. 
  • Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure. 
  • Current-use flame retardants: Maternal exposure and neurodevelopment in children of the CHAMACOS cohort. 
  • DEET (N,N-diethyl-m-toluamide) alone and in combination with permethrin increased urinary excretion of 6beta-hydroxycortisol in rats, a marker of hepatic CYP3A induction. 
  • Delayed neurotoxicity from continous low-dose oral administration of leptophos to hens. 
  • Delayed neurotoxicity from long-term low-level topical administration of leptophos to the comb of hens. 
  • Delayed neurotoxicity induced by organophosphorus compounds in the wild mallard duckling: effect of leptophos. 
  • Delayed neurotoxicity of O-ethyl O-2,4-dichlorophenyl phenylphosphonothioate: effects of a single oral dose on hens. 
  • Delayed neurotoxicity of O-ethyl O-4-nitrophenyl phenylphosphonothioate: subchronic (90 days) oral administration in hens. 
  • Delayed neurotoxicity of O-ethyl O-4-nitrophenyl phenylphosphonothioate: toxic effects of a single oral dose on the nervous system of hens. 
  • Delayed neurotoxicity of leptophos and related compounds: differential effects of subchronic oral administration of pure, technical grade and degradation products on the hen. 
  • Delayed neurotoxicity of leptophos: toxic effects on the nervous system of hens. 
  • Delayed neurotoxicity of phenylphosphonothioate esters. 
  • Delayed neurotoxicity of subchronic oral administration of leptophos to hens: recovery during four months after exposure. 
  • Detection of endocrine disrupting chemicals in samples of second trimester human amniotic fluid. 
  • Determination of diazinon, chlorpyrifos, and their metabolites in rat plasma and urine by high-performance liquid chromatography. 
  • Development of a methyl bromide collection system for fumigated farmland. 
  • Developmental cholinotoxicants: nicotine and chlorpyrifos. 
  • Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling. 
  • Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood. 
  • Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression. 
  • Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling. 
  • Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos. 
  • Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats. 
  • Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions. 
  • Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel. 
  • Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target? 
  • Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: effects on neurospecific proteins indicate changing vulnerabilities. 
  • Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation. 
  • Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. 
  • Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period? 
  • Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood. 
  • Developmental neurotoxicity of succeeding generations of insecticides. 
  • Diazinon and parathion diverge in their effects on development of noradrenergic systems. 
  • Differential metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate by rat and chicken hepatic microsomes. 
  • Disposition, elimination and metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate after subchronic dermal application in male cats. 
  • Distribution and metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate after a single oral dose in one-week old chicks. 
  • Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells. 
  • Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes. 
  • Does early-life exposure to organophosphate insecticides lead to prediabetes and obesity? 
  • Does mechanism matter? Unrelated neurotoxicants converge on cell cycle and apoptosis during neurodifferentiation. 
  • Does the developmental neurotoxicity of chlorpyrifos involve glial targets? Macromolecule synthesis, adenylyl cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells. 
  • Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos? 
  • Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging. 
  • Effect of subchronic dermal application of O-ethyl O-4-nitrophenyl phenylphosphonothioate on producing delayed neurotoxicity in hens. 
  • Effects of an insecticidal dip containing d-limonene in the cat. 
  • Effects of daily dermal application of DEET and epermethrin, alone and in combination, on sensorimotor performance, blood-brain barrier, and blood-testis barrier in rats. 
  • Effects of dietary exposure to the pyrethroid pesticide esfenvalerate on medaka (Oryzias latipes). 
  • Effects of permethrin-impregnated bed nets on malaria vectors of northern Guatemala. 
  • Effects of sub-chronic in vivo chlorpyrifos exposure on muscarinic receptors and adenylate cyclase of rat striatum. 
  • Effects of subchronic exposure to a complex mixture of persistent contaminants in male rats: systemic, immune, and reproductive effects. 
  • Efficacy of permethrin-treated bed nets in the prevention of mortality in young children in an area of high perennial malaria transmission in western Kenya. 
  • Environmental contaminants and body fat distribution. 
  • Environmental pollutants alter taste responses in the gerbil. 
  • Environmentally relevant xenoestrogen tissue concentrations correlated to biological responses in mice. 
  • Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. 
  • Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood. 
  • Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood. 
  • Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily. 
  • Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood. 
  • Fundulus heteroclitus adapted to PAHs are cross-resistant to multiple insecticides. 
  • Genome-wide study of DNA methylation alterations in response to diazinon exposure in vitro. 
  • Gestational and perinatal exposure to diazinon causes long-lasting neurobehavioral consequences in the rat. 
  • Gossypol: antagonistic effect on toxicity of insecticides to Spodoptera littoralis. 
  • Guidelines for developmental neurotoxicity and their impact on organophosphate pesticides: a personal view from an academic perspective. 
  • High performance liquid chromatographic determination of diazinon, permethrin, DEET (N, N-diethyl-m-toluamide), and their metabolites in rat plasma and urine. 
  • High-pressure liquid chromatography of neurotoxic phenylphosphonothioate esters and related compounds. 
  • Household perceptions and subjective valuations of indoor residual spraying programmes to control malaria in northern Uganda. 
  • Human antibody response to Anopheles gambiae saliva: an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control. 
  • Identification and expression of the ecdysone receptor in the harpacticoid copepod, Amphiascus tenuiremis, in response to fipronil. 
  • Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates. 
  • Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure. 
  • Impregnated bed nets for malaria control: biological success and social responsibility. 
  • Increased 8-hydroxy-2'-deoxyguanosine, a biomarker of oxidative DNA damage in rat urine following a single dermal dose of DEET (N, N-diethyl-m-toluamide), and permethrin, alone and in combination. 
  • Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine. 
  • Increasing uptake and bioactivation with development positively modulate diazinon toxicity in early life stage medaka (Oryzias latipes). 
  • Index of suspicion. 
  • Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats. 
  • Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. 
  • Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats. 
  • Interaction between neurotoxicities induced by organophosphorus and long-chain hexacarbon compounds. 
  • Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies. 
  • Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells. 
  • Isolation and insecticidal activity of mellamide from Aspergillus melleus. 
  • Isolation and insecticidal/anthelmintic activity of xanthonol, a novel bis-xanthone, from a non-sporulating fungal species. 
  • Late acute, delayed neurotoxic and cholinergic effects of S,S,S-tributyl phosphorotrithioite (Merphos) in hens. 
  • Mammary gland morphology in Sprague-Dawley rats following treatment with an organochlorine mixture in utero and neonatal genistein. 
  • Maternal exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring in late puberty. 
  • Maternal serum level of the DDT metabolite DDE in relation to fetal loss in previous pregnancies. 
  • Metabolism and pharmacokinetics of a single oral dose of O-4-bromo-2,5-dichlorophenyl O-methyl phenylphosphonothioate (Leptophos) in hens. 
  • Methyl parathion: a review of health effects. 
  • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. 
  • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. 
  • Monitoring community response to malaria control using insecticide-impregnated bed nets, curtains and residual spray at Nsukka, Nigeria. 
  • More than a Mite Contagious: Crusted Scabies. 
  • Morphologic effects of subtoxic neonatal chlorpyrifos exposure in developing rat brain: regionally selective alterations in neurons and glia. 
  • Mosquito coil emissions and health implications. 
  • Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems. 
  • Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood. 
  • Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish. 
  • Neurological deficits induced by malathion, DEET, and permethrin, alone or in combination in adult rats. 
  • Neurotoxicity resulting from coexposure to pyridostigmine bromide, deet, and permethrin: implications of Gulf War chemical exposures. 
  • Nonenzymatic functions of acetylcholinesterase splice variants in the developmental neurotoxicity of organophosphates: chlorpyrifos, chlorpyrifos oxon, and diazinon. 
  • Organophosphate exposure during a critical developmental stage reprograms adenylyl cyclase signaling in PC12 cells. 
  • Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition. 
  • Organophosphate-induced acetylcholinesterase inhibition and embryonic retinal cell necrosis in vivo in the teleost (Oryzias latipes). 
  • Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. 
  • P-glycoprotein involvement in cuticular penetration of [14C]thiodicarb in resistant tobacco budworms. 
  • Parasites and progress: ethical decision-making and the Santee-Cooper Malaria study, 1944-1949. 
  • Pattern of neurotoxicity of n-hexane, methyl n-butyl ketone, 2,5-hexanediol, and 2,5-hexanedione alone and in combination with O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens. 
  • Perinatal diazinon exposure compromises the development of acetylcholine and serotonin systems. 
  • Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain. 
  • Permethrin-impregnated bed nets for malaria control in northern Guatemala: epidemiologic impact and community acceptance. 
  • Permethrin-impregnated curtains and bed-nets prevent malaria in western Kenya. 
  • Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion. 
  • Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats. 
  • Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure. 
  • Persistent organic pollutants in two dolphin species with focus on toxaphene and polybrominated diphenyl ethers. 
  • Pharmacokinetic profile and placental transfer of a single intravenous injection of [(14)C]chlorpyrifos in pregnant rats. 
  • Pharmacokinetics and metabolism of a topically applied dose of O-4-bromo-2,5-dichlorophenyl O-methyl phenylphosphonothioate in hens. 
  • Pharmacokinetics of a neurotoxic oral dose of leptophos in hens. 
  • Physiological disposition and metabolism of O-ethyl-O-4-nitrophenyl phenylphosphonothioate in male cats following a single dermal administration. 
  • Placental transfer and pharmacokinetics of a single dermal dose of [14C]methyl parathion in rats. 
  • Potency of combined estrogenic pesticides. 
  • Prenatal and Early Postnatal Odorant Exposure Heightens Odor-Evoked Mitral Cell Responses in the Mouse Olfactory Bulb. 
  • Prenatal chlorpyrifos exposure elicits presynaptic serotonergic and dopaminergic hyperactivity at adolescence: critical periods for regional and sex-selective effects. 
  • Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor. 
  • Prenatal dexamethasone, as used in preterm labor, worsens the impact of postnatal chlorpyrifos exposure on serotonergic pathways. 
  • Prospective surveillance of semen quality in the workplace. 
  • Pyridostigmine bromide intake during the Persian Gulf War is not associated with postwar handgrip strength. 
  • Recent declines in PAH, PCB, and toxaphene levels in the northern Great Lakes as determined from high resolution sediment cores. 
  • Reduction of malaria prevalence by indoor residual spraying: a meta-regression analysis. 
  • Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation. 
  • Role of acid phosphatase in delayed neurotoxicity induced by leptophos in hens. 
  • Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel. 
  • Semi-field evaluation of the cumulative effects of a "Lethal House Lure" on malaria mosquito mortality. 
  • Sensitivity of the cat to delayed neurotoxicity induced by O-ethyl O-4-nitrophenyl phenylphosphonothioate. 
  • Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats. 
  • Sequential thin-layer chromatography of phosfolan, mephosfolan and related compounds. 
  • Serotonergic systems targeted by developmental exposure to chlorpyrifos: effects during different critical periods. 
  • Simultaneous determination of chlorpyrifos, permethrin, and their metabolites in rat plasma and urine by high-performance liquid chromatography. 
  • Simultaneous determination of malathion, permethrin, DEET (N,N-diethyl-m-toluamide), and their metabolites in rat plasma and urine using high performance liquid chromatography. 
  • Simultaneous determination of pyridostigmine bromide, N,N-diethyl-m-toluamide, permethrin, and their metabolites in rat plasma and urine by high-performance liquid chromatography. 
  • Stage sensitivity of medaka (Oryzias latipes) eggs and embryos to permethrin. 
  • Stage-dependent differences in effects of carbaryl on population growth rate in Japanese medaka (Oryzias latipes). 
  • Stage-specific toxicity of cypermethrin to medaka (Oryzias latipes) eggs and embryos using a refined methodology for an in vitro fertilization bioassay. 
  • Subchronic dermal application of N,N-diethyl m-toluamide (DEET) and permethrin to adult rats, alone or in combination, causes diffuse neuronal cell death and cytoskeletal abnormalities in the cerebral cortex and the hippocampus, and Purkinje neuron loss in the cerebellum. 
  • Suppression of a P450 hydroxylase gene in plant trichome glands enhances natural-product-based aphid resistance. 
  • Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior. 
  • Testicular germ-cell apoptosis in stressed rats following combined exposure to pyridostigmine bromide, N,N-diethyl m-toluamide (DEET), and permethrin. 
  • The absorption, distribution, excretion, and metabolism of a single oral dose of O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens. 
  • The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent. 
  • The effectiveness of insecticide-impregnated bed nets in reducing cases of malaria infection: a meta-analysis of published results. 
  • The influence of individual preventive measures on the clinical severity of malaria among Nigerian children. 
  • The joint neurotoxic action of inhaled methyl butyl ketone vapor and dermally applied O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens: potentiating effect. 
  • The organophosphate pesticide chlorpyrifos affects form deprivation myopia. 
  • The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine. 
  • Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium. 
  • Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance. 
  • Toxicity of a formulation of the insecticide indoxacarb to the tarnished plant bug, Lygus lineolaris (Hemiptera: Miridae), and the big-eyed bug, Geocoris punctipes (Hemiptera: Lygaeidae). 
  • Toxicity of stormwater runoff after dormant spray application of diazinon and esfenvalerate (Asana) in a French prune orchard, Glenn county, California, USA. 
  • Toxicokinetics and metabolism of delayed neurotoxic organophosphorus esters. 
  • Transcriptional biomarkers distinguish between vulnerable periods for developmental neurotoxicity of chlorpyrifos: Implications for toxicogenomics. 
  • Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells. 
  • Ultraviolet photolysis of chlorpyrifos: developmental neurotoxicity modeled in PC12 cells. 
  • Unrelated developmental neurotoxicants elicit similar transcriptional profiles for effects on neurotrophic factors and their receptors in an in vitro model. 
  • Urinary excretion of metabolites following a single dermal dose of [14C]methyl parathion in pregnant rats. 
  • Use of protein phosphatase inhibitors. 
  • Using charcoal as base material reduces mosquito coil emissions of toxins. 
  • Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze. 
  • Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits. 
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  Keywords of People

  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Duke Innovation & Entrepreneurship