-
Subject Areas on Research
-
A Voucher System To Speed Review Could Promote A New Generation Of Insecticides To Fight Vector-Borne Diseases.
-
A mutation in the intracellular loop III/IV of mosquito sodium channel synergizes the effect of mutations in helix IIS6 on pyrethroid resistance.
-
A negative charge in transmembrane segment 1 of domain II of the cockroach sodium channel is critical for channel gating and action of pyrethroid insecticides.
-
A randomized longitudinal factorial design to assess malaria vector control and disease management interventions in rural Tanzania.
-
A residue in the transmembrane segment 6 of domain I in insect and mammalian sodium channels regulate differential sensitivities to pyrethroid insecticides.
-
A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids.
-
Action of six pyrethrins purified from the botanical insecticide pyrethrum on cockroach sodium channels expressed in Xenopus oocytes.
-
Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish.
-
Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish.
-
Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids.
-
Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure.
-
Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels.
-
Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells.
-
An alanine in segment 3 of domain III (IIIS3) of the cockroach sodium channel contributes to the low pyrethroid sensitivity of an alternative splice variant.
-
An examination of the proconvulsant actions of pyrethroid insecticides using pentylenetetrazol and amygdala kindling seizure models.
-
An important role of a pyrethroid-sensing residue F1519 in the action of the N-alkylamide insecticide BTG 502 on the cockroach sodium channel.
-
An invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvae.
-
Analysis of the action of lidocaine on insect sodium channels.
-
Anti-Müllerian hormone and lifestyle, reproductive, and environmental factors among women in rural South Africa.
-
Bayesian isotonic regression and trend analysis.
-
Bayesian multivariate logistic regression.
-
Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation.
-
Benzo[a]pyrene impairs neurodifferentiation in PC12 cells.
-
Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade.
-
Chlordanes in the indoor and outdoor air of three U.S. cities.
-
Chlorpyrifos accumulation patterns for child-accessible surfaces and objects and urinary metabolite excretion by children for 2 weeks after crack-and-crevice application.
-
Chlorpyrifos developmental neurotoxicity: interaction with glucocorticoids in PC12 cells.
-
Chlorpyrifos exposure of developing zebrafish: effects on survival and long-term effects on response latency and spatial discrimination.
-
Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes.
-
Chlorpyrifos targets developing glia: effects on glial fibrillary acidic protein.
-
Chronology of sodium channel mutations associated with pyrethroid resistance in Aedes aegypti.
-
Co-exposure to pyridostigmine bromide, DEET, and/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity.
-
Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity.
-
Comparative field evaluation of combinations of long-lasting insecticide treated nets and indoor residual spraying, relative to either method alone, for malaria prevention in an area where the main vector is Anopheles arabiensis.
-
Comparative toxicities of selected compounds to nauplii of Balanus amphitrite amphitrite Darwin and Artemia sp.
-
Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions.
-
Contact toxicity of permethrin-impregnated fabric to Hyalomma anatolicum excavatum (Acari: Ixodidae): effects of laundering and exposure and recovery times.
-
Contamination of rural surface and ground water by endosulfan in farming areas of the Western Cape, South Africa.
-
Cost of microbial larviciding for malaria control in rural Tanzania.
-
Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure.
-
Current-use flame retardants: Maternal exposure and neurodevelopment in children of the CHAMACOS cohort.
-
DSC1 channel-dependent developmental regulation of pyrethroid susceptibility in Drosophila melanogaster.
-
Detection of endocrine disrupting chemicals in samples of second trimester human amniotic fluid.
-
Development of a methyl bromide collection system for fumigated farmland.
-
Developmental cholinotoxicants: nicotine and chlorpyrifos.
-
Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling.
-
Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood.
-
Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression.
-
Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling.
-
Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos.
-
Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats.
-
Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions.
-
Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel.
-
Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target?
-
Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: effects on neurospecific proteins indicate changing vulnerabilities.
-
Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation.
-
Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells.
-
Developmental neurotoxicity of chlorpyrifos: what is the vulnerable period?
-
Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood.
-
Developmental neurotoxicity of succeeding generations of insecticides.
-
Diazinon and parathion diverge in their effects on development of noradrenergic systems.
-
Discovery of a Novel Series of Tricyclic Oxadiazine 4a-Methyl Esters Based on Indoxacarb as Potential Sodium Channel Blocker/Modulator Insecticides.
-
Distinct roles of the DmNav and DSC1 channels in the action of DDT and pyrethroids.
-
Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells.
-
Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes.
-
Does early-life exposure to organophosphate insecticides lead to prediabetes and obesity?
-
Does mechanism matter? Unrelated neurotoxicants converge on cell cycle and apoptosis during neurodifferentiation.
-
Does the developmental neurotoxicity of chlorpyrifos involve glial targets? Macromolecule synthesis, adenylyl cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells.
-
Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos?
-
Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging.
-
Effect of a fluvalinate-resistance-associated sodium channel mutation from varroa mites on cockroach sodium channel sensitivity to fluvalinate, a pyrethroid insecticide.
-
Effects of an insecticidal dip containing d-limonene in the cat.
-
Effects of daily dermal application of DEET and epermethrin, alone and in combination, on sensorimotor performance, blood-brain barrier, and blood-testis barrier in rats.
-
Effects of dietary exposure to the pyrethroid pesticide esfenvalerate on medaka (Oryzias latipes).
-
Effects of permethrin-impregnated bed nets on malaria vectors of northern Guatemala.
-
Effects of subchronic exposure to a complex mixture of persistent contaminants in male rats: systemic, immune, and reproductive effects.
-
Efficacy of permethrin-treated bed nets in the prevention of mortality in young children in an area of high perennial malaria transmission in western Kenya.
-
Elucidation of pyrethroid and DDT receptor sites in the voltage-gated sodium channel.
-
Environmental contaminants and body fat distribution.
-
Environmentally relevant xenoestrogen tissue concentrations correlated to biological responses in mice.
-
Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay.
-
Evidence for Dual Binding Sites for 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) in Insect Sodium Channels.
-
Evolutionary adaptation of the amino acid and codon usage of the mosquito sodium channel following insecticide selection in the field mosquitoes.
-
Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood.
-
Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood.
-
Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily.
-
Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood.
-
Fine scale spatial investigation of multiple insecticide resistance and underlying target-site and metabolic mechanisms in Anopheles gambiae in central Côte d'Ivoire.
-
Fundulus heteroclitus adapted to PAHs are cross-resistant to multiple insecticides.
-
Genome-wide study of DNA methylation alterations in response to diazinon exposure in vitro.
-
Gestational and perinatal exposure to diazinon causes long-lasting neurobehavioral consequences in the rat.
-
Guidelines for developmental neurotoxicity and their impact on organophosphate pesticides: a personal view from an academic perspective.
-
Household perceptions and subjective valuations of indoor residual spraying programmes to control malaria in northern Uganda.
-
Identification and expression of the ecdysone receptor in the harpacticoid copepod, Amphiascus tenuiremis, in response to fipronil.
-
Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides.
-
Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates.
-
Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure.
-
Impregnated bed nets for malaria control: biological success and social responsibility.
-
Increasing uptake and bioactivation with development positively modulate diazinon toxicity in early life stage medaka (Oryzias latipes).
-
Index of suspicion.
-
Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats.
-
Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
-
Insect sodium channels and insecticide resistance.
-
Insight into the Mode of Action of Haedoxan A from Phryma leptostachya.
-
Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies.
-
Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells.
-
Isolation and insecticidal activity of mellamide from Aspergillus melleus.
-
Isolation and insecticidal/anthelmintic activity of xanthonol, a novel bis-xanthone, from a non-sporulating fungal species.
-
Mammary gland morphology in Sprague-Dawley rats following treatment with an organochlorine mixture in utero and neonatal genistein.
-
Maternal serum level of the DDT metabolite DDE in relation to fetal loss in previous pregnancies.
-
Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells.
-
Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells.
-
Molecular Mechanism of Action and Selectivity of Sodium Ch annel Blocker Insecticides.
-
Molecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb.
-
Molecular basis of selective resistance of the bumblebee BiNav1 sodium channel to tau-fluvalinate.
-
Molecular biology of insect sodium channels and pyrethroid resistance.
-
Molecular determinants on the insect sodium channel for the specific action of type II pyrethroid insecticides.
-
Molecular evidence of sequential evolution of DDT- and pyrethroid-resistant sodium channel in Aedes aegypti.
-
Monitoring community response to malaria control using insecticide-impregnated bed nets, curtains and residual spray at Nsukka, Nigeria.
-
More than a Mite Contagious: Crusted Scabies.
-
Morphologic effects of subtoxic neonatal chlorpyrifos exposure in developing rat brain: regionally selective alterations in neurons and glia.
-
Mosquito coil emissions and health implications.
-
Multiple mutations and mutation combinations in the sodium channel of permethrin resistant mosquitoes, Culex quinquefasciatus.
-
Mutations in the transmembrane helix S6 of domain IV confer cockroach sodium channel resistance to sodium channel blocker insecticides and local anesthetics.
-
Mutations of two acidic residues at the cytoplasmic end of segment IIIS6 of an insect sodium channel have distinct effects on pyrethroid resistance.
-
Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems.
-
Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood.
-
Neurobehavioral impairments caused by developmental imidacloprid exposure in zebrafish.
-
Neurological deficits induced by malathion, DEET, and permethrin, alone or in combination in adult rats.
-
Nonenzymatic functions of acetylcholinesterase splice variants in the developmental neurotoxicity of organophosphates: chlorpyrifos, chlorpyrifos oxon, and diazinon.
-
Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin.
-
Organophosphate exposure during a critical developmental stage reprograms adenylyl cyclase signaling in PC12 cells.
-
Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition.
-
Organophosphate-induced acetylcholinesterase inhibition and embryonic retinal cell necrosis in vivo in the teleost (Oryzias latipes).
-
Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells.
-
Parasites and progress: ethical decision-making and the Santee-Cooper Malaria study, 1944-1949.
-
Perinatal diazinon exposure compromises the development of acetylcholine and serotonin systems.
-
Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain.
-
Permethrin-impregnated bed nets for malaria control in northern Guatemala: epidemiologic impact and community acceptance.
-
Permethrin-impregnated curtains and bed-nets prevent malaria in western Kenya.
-
Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion.
-
Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats.
-
Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure.
-
Persistent organic pollutants in two dolphin species with focus on toxaphene and polybrominated diphenyl ethers.
-
Potency of combined estrogenic pesticides.
-
Prenatal and Early Postnatal Odorant Exposure Heightens Odor-Evoked Mitral Cell Responses in the Mouse Olfactory Bulb.
-
Prenatal chlorpyrifos exposure elicits presynaptic serotonergic and dopaminergic hyperactivity at adolescence: critical periods for regional and sex-selective effects.
-
Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor.
-
Prenatal dexamethasone, as used in preterm labor, worsens the impact of postnatal chlorpyrifos exposure on serotonergic pathways.
-
Prospective surveillance of semen quality in the workplace.
-
Pthiriasis capitis.
-
Pyridostigmine bromide intake during the Persian Gulf War is not associated with postwar handgrip strength.
-
Recent declines in PAH, PCB, and toxaphene levels in the northern Great Lakes as determined from high resolution sediment cores.
-
Reduction of malaria prevalence by indoor residual spraying: a meta-regression analysis.
-
Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation.
-
Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel.
-
Semi-field evaluation of the cumulative effects of a "Lethal House Lure" on malaria mosquito mortality.
-
Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats.
-
Serotonergic systems targeted by developmental exposure to chlorpyrifos: effects during different critical periods.
-
Stage sensitivity of medaka (Oryzias latipes) eggs and embryos to permethrin.
-
Stage-dependent differences in effects of carbaryl on population growth rate in Japanese medaka (Oryzias latipes).
-
Stage-specific toxicity of cypermethrin to medaka (Oryzias latipes) eggs and embryos using a refined methodology for an in vitro fertilization bioassay.
-
Suppression of a P450 hydroxylase gene in plant trichome glands enhances natural-product-based aphid resistance.
-
Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior.
-
Synergism of chlorpyrifos against the German cockroach, Blattella germanica.
-
Synergistic interaction between two cockroach sodium channel mutations and a tobacco budworm sodium channel mutation in reducing channel sensitivity to a pyrethroid insecticide.
-
Testicular germ-cell apoptosis in stressed rats following combined exposure to pyridostigmine bromide, N,N-diethyl m-toluamide (DEET), and permethrin.
-
The Drosophila Sodium Channel 1 (DSC1): The founding member of a new family of voltage-gated cation channels.
-
The Receptor Site and Mechanism of Action of Sodium Channel Blocker Insecticides.
-
The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent.
-
The effectiveness of insecticide-impregnated bed nets in reducing cases of malaria infection: a meta-analysis of published results.
-
The influence of individual preventive measures on the clinical severity of malaria among Nigerian children.
-
The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine.
-
Three sodium channel mutations from Aedes albopictus confer resistance to Type I, but not Type II pyrethroids.
-
Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium.
-
Toxicity of a formulation of the insecticide indoxacarb to the tarnished plant bug, Lygus lineolaris (Hemiptera: Miridae), and the big-eyed bug, Geocoris punctipes (Hemiptera: Lygaeidae).
-
Toxicity of stormwater runoff after dormant spray application of diazinon and esfenvalerate (Asana) in a French prune orchard, Glenn county, California, USA.
-
Transcriptional biomarkers distinguish between vulnerable periods for developmental neurotoxicity of chlorpyrifos: Implications for toxicogenomics.
-
Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells.
-
Ultraviolet photolysis of chlorpyrifos: developmental neurotoxicity modeled in PC12 cells.
-
Unrelated developmental neurotoxicants elicit similar transcriptional profiles for effects on neurotrophic factors and their receptors in an in vitro model.
-
Use of alternative bioassays to explore the impact of pyrethroid resistance on LLIN efficacy.
-
Use of non-mammalian alternative models for neurotoxicological study.
-
Use of protein phosphatase inhibitors.
-
Using charcoal as base material reduces mosquito coil emissions of toxins.
-
Ventral hippocampal alpha 7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze.
-
Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits.
-
Keywords of People