Sleep Initiation and Maintenance Disorders
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Subject Areas on Research
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A 12-week, randomized, double-blind, placebo-controlled study evaluating the effect of eszopiclone 2 mg on sleep/wake function in older adults with primary and comorbid insomnia.
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A WASO sub-group analysis of a 6-month study of eszopiclone 3 mg.
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A case of fatal familial insomnia: diagnostic and therapeutic approaches.
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A comparison of placebo and no-treatment during a hypnotic clinical trial.
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A comparison of rates of residual insomnia symptoms following pharmacotherapy or cognitive-behavioral therapy for major depressive disorder.
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A comparison of the efficacy of stimulus control for medicated and nonmedicated insomniacs.
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A compendium of placebo-controlled trials of the risks/benefits of pharmacological treatments for insomnia: the empirical basis for U.S. clinical practice.
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A multi-component cognitive-behavioral intervention for sleep disturbance in veterans with PTSD: a pilot study.
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A pilot study investigating the utility of the cognitive-behavioral model of insomnia in early-stage lung cancer patients.
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A polysomnography study of eszopiclone in elderly patients with insomnia.
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A primary care "friendly" cognitive behavioral insomnia therapy.
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A randomized, double-blind, placebo-controlled trial of eszopiclone for the treatment of insomnia in patients with chronic low back pain.
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A team approach: comprehensive evaluation for functional decline in older patients.
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Accuracy of sleep perceptions among insomnia sufferers and normal sleepers.
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Actigraphy-Derived Sleep Efficiency Is Associated With Endothelial Function in Men and Women With Untreated Hypertension.
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Adverse Effects of Hypnotic Medications.
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Ambulatory cassette polysomnography: findings from a large cohort of drug-free insomnia patients.
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An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia.
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An exploratory analysis of the association of circadian rhythm dysregulation and insomnia with suicidal ideation over the course of treatment in individuals with depression, insomnia, and suicidal ideation.
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Are Patients with Childhood Onset of Insomnia and Depression More Difficult to Treat Than Are Those with Adult Onsets of These Disorders? A Report from the TRIAD Study.
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Assessing depression symptoms in those with insomnia: an examination of the beck depression inventory second edition (BDI-II).
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Assessing insomnia severity in depression: comparison of depression rating scales and sleep diaries.
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Association of Sleep and β-Amyloid Pathology Among Older Cognitively Unimpaired Adults.
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Associations between sleep difficulties and risk factors for cardiovascular disease in veterans and active duty military personnel of the Iraq and Afghanistan conflicts.
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Behavioral Treatment of Insomnia and Sleep Disturbances in School-Aged Children and Adolescents.
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Behavioral insomnia therapy for fibromyalgia patients: a randomized clinical trial.
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Blinding and bias in a hypnotic clinical trial.
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British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders.
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British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: An update.
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Change in sleep symptoms across Cognitive Processing Therapy and Prolonged Exposure: a longitudinal perspective.
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Circadian Preference as a Moderator of Depression Outcome Following Cognitive Behavioral Therapy for Insomnia Plus Antidepressant Medications: A Report From the TRIAD Study.
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Classifying insomnia in a clinically useful way.
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Clinical Management of Insomnia Disorder.
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Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.
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Clinical and imaging findings suggesting human herpesvirus 6 encephalitis.
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Clinical features of depression in Asia: results of a large prospective, cross-sectional study.
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Clinical profile of suvorexant for the treatment of insomnia over 3 months in women and men: subgroup analysis of pooled phase-3 data.
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Cognitive Behavioral Insomnia Therapy for Those With Insomnia and Depression: A Randomized Controlled Clinical Trial.
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Cognitive and behavioral anomalies among insomnia patients with mixed restless legs and periodic limb movement disorder.
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Cognitive behavioral therapy for patients with primary insomnia or insomnia associated predominantly with mixed psychiatric disorders: a randomized clinical trial.
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Cognitive behavioral therapy for treatment of chronic primary insomnia: a randomized controlled trial.
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Cognitive-behavioral therapy for primary insomnia.
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Cognitive-behavioral treatment for comorbid insomnia and osteoarthritis pain in primary care: the lifestyles randomized controlled trial.
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Comorbid Insomnia and Sleep Apnea are Associated with Greater Downstream Health Care Utilization and Chronic Opioid Use after Arthroscopic Hip Surgery.
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Comparative effects of nefazodone and fluoxetine on sleep in outpatients with major depressive disorder.
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Comparison of diary-derived bladder and sleep measurements across OAB individuals, primary insomniacs, and healthy controls.
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Comparison of polysomnographic data in age-, sex- and Axis I psychiatric diagnosis matched HIV-seropositive and HIV-seronegative insomnia patients.
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Contribution of cancer symptoms, dysfunctional sleep related thoughts, and sleep inhibitory behaviors to the insomnia process in breast cancer survivors: a daily process analysis.
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Cost-effectiveness of digital cognitive behavioral therapy (Sleepio) for insomnia: a Markov simulation model in the United States.
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Current, emerging, and newly available insomnia medications.
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D1 and D2 antagonists reverse the effects of appetite suppressants on weight loss, food intake, locomotion, and rebalance spiking inhibition in the rat NAc shell.
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Daytime sleepiness, poor sleep quality, eveningness chronotype, and common mental disorders among Chilean college students.
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Defining insomnia: quantitative criteria for insomnia severity and frequency.
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Depression and insomnia in women.
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Design of the National Adaptive Trial for PTSD-related Insomnia (NAP Study), VA Cooperative Study Program (CSP) #2016.
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Differential effects of nefazodone and cognitive behavioral analysis system of psychotherapy on insomnia associated with chronic forms of major depression.
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Do our methods lead to insomniacs' madness?: Daytime testing after laboratory and home-based polysomnographic studies.
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Does cognitive-behavioral insomnia therapy alter dysfunctional beliefs about sleep?
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Does physiological hyperarousal enhance error rates among insomnia sufferers?
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Does pretreatment insomnia or anxiety predict acute response to bupropion SR?
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Dose-response effects of cognitive-behavioral insomnia therapy: a randomized clinical trial.
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Down Syndrome Disintegrative Disorder: New-Onset Autistic Regression, Dementia, and Insomnia in Older Children and Adolescents With Down Syndrome.
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Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind, randomized, placebo-controlled clinical trials in the HUMMINGBIRD clinical program.
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Effectiveness of Sequential Psychological and Medication Therapies for Insomnia Disorder: A Randomized Clinical Trial.
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Effects of a Course of Right Unilateral Ultrabrief Pulse Electroconvulsive Therapy Combined With Venlafaxine on Insomnia Symptoms in Elderly Depressed Patients.
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Effects of an Internet-Based Cognitive Behavioral Therapy for Insomnia Program on Work Productivity: A Secondary Analysis.
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Efficacy and Safety of Doxepin 1 mg and 3 mg in a 12-week Sleep Laboratory and Outpatient Trial of Elderly Subjects with Chronic Primary Insomnia.
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Efficacy and safety of doxepin 3 and 6 mg in a 35-day sleep laboratory trial in adults with chronic primary insomnia.
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Efficacy of Cognitive-Behavioral Therapy for Insomnia Combined With Antidepressant Pharmacotherapy in Patients With Comorbid Depression and Insomnia: A Randomized Controlled Trial.
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Efficacy of Digital Cognitive Behavioral Therapy for the Treatment of Insomnia Symptoms Among Pregnant Women: A Randomized Clinical Trial.
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Efficacy of Transcendental Meditation to Reduce Stress Among Health Care Workers: A Randomized Clinical Trial.
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Efficacy of felbamate in therapy for partial epilepsy in children.
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Esmirtazapine in non-elderly adult patients with primary insomnia: efficacy and safety from a randomized, 6-week sleep laboratory trial.
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Eszopiclone co-administered with fluoxetine in patients with insomnia coexisting with major depressive disorder.
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Eszopiclone coadministered with escitalopram in patients with insomnia and comorbid generalized anxiety disorder.
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Evaluating lemborexant for the treatment of insomnia.
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Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression.
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Evaluation of temazepam and diphenhydramine as hypnotics in a nursing-home population.
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Extended-release bupropion for patients with major depressive disorder presenting with symptoms of reduced energy, pleasure, and interest: findings from a randomized, double-blind, placebo-controlled study.
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Family conflict in childhood: a predictor of later insomnia.
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Functional decline in older adults.
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Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms.
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Group interventions for co-morbid insomnia and osteoarthritis pain in primary care: the lifestyles cluster randomized trial design.
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Home is where sleep is: an ecological approach to test the validity of actigraphy for the assessment of insomnia.
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How many nights are enough? The short-term stability of sleep parameters in elderly insomniacs and normal sleepers.
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Hypnotic Medications and Suicide: Risk, Mechanisms, Mitigation, and the FDA.
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Hypnotics should be considered for the initial treatment of chronic insomnia. Pro.
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Impact of sleep complaints and depression outcomes among participants in the standard medical intervention and long-term exercise study of exercise and pharmacotherapy for depression.
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Improving sleep with mindfulness and acceptance: a metacognitive model of insomnia.
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Incidence and remission of insomnia among elderly adults in a biracial cohort.
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Incidence and remission of insomnia among elderly adults: an epidemiologic study of 6,800 persons over three years.
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Increasing access to and utilization of cognitive behavioral therapy for insomnia (CBT-I): a narrative review.
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Individual- and Ad-Level Predictors of Perceptions of Serious and Actionable Risks in Direct-to-Consumer Prescription Drug TV Advertising.
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Information without Implementation: A Practical Example for Developing a Best Practice Education Control Group.
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Insomnia Patients With Objective Short Sleep Duration Have a Blunted Response to Cognitive Behavioral Therapy for Insomnia.
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Insomnia and heart disease: a review of epidemiologic studies.
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Insomnia and the eye of the beholder: are there clinical markers of objective sleep disturbances among adults with and without insomnia complaints?
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Insomnia disorder.
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Insomnia in HIV-infected patients: pathophysiologic implications.
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Insomnia in United States military veterans: An integrated theoretical model.
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Insomnia in patients with depression: a STAR*D report.
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Insomnia in women.
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Insomnia is frequent in schizophrenia and associated with night eating and obesity.
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Insomnia symptoms as a cause of type 2 diabetes Incidence: a 20 year cohort study.
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Integration of behavioral and relaxation approaches into the treatment of chronic pain and insomnia. NIH Technology Assessment Panel on Integration of Behavioral and Relaxation Approaches into the Treatment of Chronic Pain and Insomnia.
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Introduction: Definitions, measurements, and management in insomnia.
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Is insomnia associated with deficits in neuropsychological functioning? Evidence from a population-based study.
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Joint analysis of stochastic processes with application to smoking patterns and insomnia.
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Long-Term Trazodone Use and Cognition: A Potential Therapeutic Role for Slow-Wave Sleep Enhancers.
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Long-term efficacy and safety of zolpidem extended-release 12.5 mg, administered 3 to 7 nights per week for 24 weeks, in patients with chronic primary insomnia: a 6-month, randomized, double-blind, placebo-controlled, parallel-group, multicenter study.
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Long-term issues in the treatment of sleep disorders.
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Long-term, non-nightly administration of zolpidem in the treatment of patients with primary insomnia.
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Longitudinal associations between parent-child relationship quality and insomnia for aging parents: The mediating role of depressive symptoms.
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Maternal insomnia and children's family socialization environments.
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Mental health antecedents of early midlife insomnia: evidence from a four-decade longitudinal study.
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More on melatonin.
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Multicenter, double-blind comparison of sertraline and placebo in the treatment of posttraumatic stress disorder.
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NREM sleep EEG frequency spectral correlates of sleep complaints in primary insomnia subtypes.
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Natural sleep and its seasonal variations in three pre-industrial societies.
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Neurovegetative symptoms in chronic pain and depression.
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New Developments in Insomnia Medications of Relevance to Mental Health Disorders.
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Nightly treatment of primary insomnia with eszopiclone for six months: effect on sleep, quality of life, and work limitations.
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Nocturnal blood pressure non-dipping, posttraumatic stress disorder, and sleep quality in women.
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Nonsuicidal self-injury, sleep quality, and shame response to a laboratory stress task.
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Novel sublingual low-dose zolpidem tablet reduces latency to sleep onset following spontaneous middle-of-the-night awakening in insomnia in a randomized, double-blind, placebo-controlled, outpatient study.
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Objective but Not Subjective Short Sleep Duration Associated with Increased Risk for Hypertension in Individuals with Insomnia.
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Omitted Conflict of Interest Disclosures.
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Open trial of nefazodone for combat-related posttraumatic stress disorder.
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Optimizing computation of overnight decline in delta power: Evidence for slower rate of decline in delta power in insomnia patients.
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Orexin receptor antagonists for the treatment of insomnia and potential treatment of other neuropsychiatric indications.
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Osteoarthritis and sleep: the Johnston County Osteoarthritis Project.
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PTSD symptoms and tinnitus severity: An analysis of veterans with posttraumatic headaches.
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Panel discussion: changing how we think about insomnia.
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Pharmacological advances in the treatment of insomnia.
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Pilot prospective study of post-surgery sleep and EEG predictors of post-operative delirium.
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Polysomnographic assessment of DIMS: empirical evaluation of its diagnostic value.
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Practice guideline: Treatment for insomnia and disrupted sleep behavior in children and adolescents with autism spectrum disorder: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
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Pre-treatment insomnia as a predictor of single and combination antidepressant outcomes: a CO-MED report.
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Predictors of depression recovery in HIV-infected individuals managed through measurement-based care in infectious disease clinics.
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Pretherapy cognitive dispositions and treatment outcome in cognitive behavior therapy for insomnia.
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Prevalence of and characteristics associated with insomnia and obstructive sleep apnea among veterans with knee and hip osteoarthritis.
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Prevalence of insomnia disorder and sleep apnea in a sample of veterans at risk for cardiovascular disease.
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Prevalence rates and correlates of insomnia disorder in post-9/11 veterans enrolling in VA healthcare.
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Provider-supported self-management cognitive behavioral therapy for insomnia (Tele-Self CBTi): Protocol for a randomized controlled trial.
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Psychological Pathways Linking Parent-Child Relationships to Objective and Subjective Sleep Among Older Adults.
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Psychomotor performance deficits and their relation to prior nights' sleep among individuals with primary insomnia.
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Racial/ethnic differences in sleep quality among older adults with osteoarthritis.
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Randomized controlled trial of digital cognitive behavior therapy for prenatal insomnia symptoms: effects on postpartum insomnia and mental health.
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Recognizing and managing insomnia in primary care and specialty settings.
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Recommended patient-reported core set of symptoms to measure in adult cancer treatment trials.
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Reducing Suicidal Ideation Through Insomnia Treatment (REST-IT): A Randomized Clinical Trial.
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Regularity and Timing of Sleep Patterns and Behavioral Health Among Adolescents.
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Relationship Between Attitudes and Beliefs About Sleep, Sleep Disturbance, and Pain Interference in Patients With Spinal Pain.
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Relaxation therapy for insomnia: nighttime and day time effects.
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Relaxation to assist sleep medication withdrawal.
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Residual sleep disturbances following PTSD treatment in active duty military personnel.
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Residual symptoms after remission of major depressive disorder with citalopram and risk of relapse: a STAR*D report.
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Review of the histamine system and the clinical effects of H1 antagonists: basis for a new model for understanding the effects of insomnia medications.
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Safety and efficacy of suvorexant during 1-year treatment of insomnia with subsequent abrupt treatment discontinuation: a phase 3 randomised, double-blind, placebo-controlled trial.
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Selegiline transdermal system for the treatment of major depressive disorder: an 8-week, double-blind, placebo-controlled, flexible-dose titration trial.
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Sensitivity and specificity of polysomnographic criteria for defining insomnia.
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Sequential psychological and pharmacological therapies for comorbid and primary insomnia: study protocol for a randomized controlled trial.
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Serious and actionable risks, plus disclosure: Investigating an alternative approach for presenting risk information in prescription drug television advertisements.
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Short-term improvement in insomnia symptoms predicts long-term improvements in sleep, pain, and fatigue in older adults with comorbid osteoarthritis and insomnia.
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Should Internet Cognitive Behavioral Therapy for Insomnia Be the Primary Treatment Option for Insomnia?: Toward Getting More SHUTi.
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Should we be anxious when assessing anxiety using the Beck Anxiety Inventory in clinical insomnia patients?
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Single-Item Measures for Detecting Sleep Problems in United States Military Veterans.
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Sleep Disturbance, Diabetes, and Cardiovascular Disease in Postmenopausal Veteran Women.
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Sleep EEG predictors and correlates of the response to cognitive behavioral therapy for insomnia.
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Sleep complaints among elderly persons: an epidemiologic study of three communities.
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Sleep difficulties and alcohol use motives in female rape victims with posttraumatic stress disorder.
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Sleep disorder symptoms are associated with greater posttraumatic stress and anger symptoms in US Army service members seeking treatment for posttraumatic stress disorder.
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Sleep disturbance and baroreceptor sensitivity in women with posttraumatic stress disorder.
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Sleep disturbance in euthymic bipolar patients.
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Sleep disturbances, circadian activity, and nocturnal light exposure characterize high risk for and current depression in adolescence.
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Sleep in the laboratory and sleep at home: comparisons of older insomniacs and normal sleepers.
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Sleep quality and prostate cancer aggressiveness: Results from the REDUCE trial.
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Social class and gender patterning of insomnia symptoms and psychiatric distress: a 20-year prospective cohort study.
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Subtyping primary insomnia: is sleep state misperception a distinct clinical entity?
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Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia.
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Suvorexant in Elderly Patients with Insomnia: Pooled Analyses of Data from Phase III Randomized Controlled Clinical Trials.
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Suvorexant in Patients With Insomnia: Results From Two 3-Month Randomized Controlled Clinical Trials.
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Suvorexant in Patients with Insomnia: Pooled Analyses of Three-Month Data from Phase-3 Randomized Controlled Clinical Trials.
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Telemedicine-delivered cognitive-behavioral therapy for insomnia in alcohol use disorder (AUD): study protocol for a randomized controlled trial.
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Testing proportionality in the proportional odds model fitted with GEE.
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Testing the reliability and validity of DSM-IV-TR and ICSD-2 insomnia diagnoses. Results of a multitrait-multimethod analysis.
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The Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea: Synopsis of the 2019 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guidelines.
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The association of comorbid conditions with patient-reported outcomes in Veterans with hip and knee osteoarthritis.
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The association of fatigue with depression and insomnia in HIV-seropositive patients: a pilot study.
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The changing perspective on chronic insomnia management.
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The consensus sleep diary: standardizing prospective sleep self-monitoring.
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The effect of insomnia definitions, terminology, and classifications on clinical practice.
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The effect of vestibular stimulation in a four-hour sleep phase advance model of transient insomnia.
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The empirical identification of insomnia subtypes: a cluster analytic approach.
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The impact of eszopiclone on sleep and cognition in patients with schizophrenia and insomnia: a double-blind, randomized, placebo-controlled trial.
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The incidence and temporal patterning of insomnia: a second study.
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The influence of menopause status and postmenopausal use of hormone therapy on presentation of major depression in women.
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The longitudinal course of insomnia symptoms: inequalities by sex and occupational class among two different age cohorts followed for 20 years in the west of Scotland.
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The pharmacologic management of insomnia in patients with HIV.
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The possibility of preventing functional impairment due to sleep loss by pharmacologically enhancing sleep.
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The role of pre-sleep arousal in the connection between insomnia and suicide risk.
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The sleep effects of lurasidone: a placebo-controlled cross-over study using a 4-h phase-advance model of transient insomnia.
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The treatment of primary insomnia.
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Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia.
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Trajectories of Insomnia in Adults After Traumatic Brain Injury.
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Treating insomnia in depression: Insomnia related factors predict long-term depression trajectories.
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Treating the health, quality of life, and functional impairments in insomnia.
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Treatment of comorbid sleep disorders and posttraumatic stress disorder in active duty military: Design and methodology of a randomized clinical trial.
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Treatment of insomnia in depressed insomniacs: effects on health-related quality of life, objective and self-reported sleep, and depression.
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Understanding the sleep-wake cycle: sleep, insomnia, and the orexin system.
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Using difficulty resuming sleep to define nocturnal awakenings.
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Veterans Affairs Primary Care Provider Perceptions of Insomnia Treatment.
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What Is Insomnia?
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Work-Related Stress, Psychosocial Resources, and Insomnia Symptoms Among Older Black Workers.
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Worsening Anxiety, Irritability, Insomnia, or Panic Predicts Poorer Antidepressant Treatment Outcomes: Clinical Utility and Validation of the Concise Associated Symptom Tracking (CAST) Scale.
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Zolpidem for persistent insomnia in SSRI-treated depressed patients.
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Keywords of People