Intestinal Absorption

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  Subject Areas on Research

  • A comparison of oral and rectal absorption of L-dopa esters in rats and mice. 
  • A physicochemical study of fat absorption in rats. Limitation of methods in vitro. 
  • A simplified single stage total hepatectomy in the rat with maintenance of gastrointestinal absorptive function. 
  • Adjustment of iron intake for dietary enhancers and inhibitors in population studies: bioavailable iron in rural and urban residing Russian women and children. 
  • Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex. 
  • An overview of calcium homeostasis in humans. 
  • Analysis of the E399D mutation in SLC11A2. 
  • Assessment and significance of bacterial overgrowth in the small bowel. 
  • Calcium stone disease: an overview. 
  • Clinical and biochemical presentation of gouty diathesis: comparison of uric acid versus pure calcium stone formation. 
  • Commentary on: ferrokinetics in the syndrome of familial hypoferremic microcytic anemia with iron malabsorption. 
  • Comparison of Glucosamine Absorption After Administration of Oral Liquid, Chewable, and Tablet Formulations to Dogs. 
  • Complexation hydrogels for oral protein delivery: an in vitro assessment of the insulin transport-enhancing effects following dissolution in simulated digestive fluids. 
  • Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women. 
  • Differences in the absorption, metabolism and biliary excretion of a diastereomeric pair of alphavbeta3-antagonists in rat: limited role of P-glycoprotein. 
  • Diminished and erratic absorption of ergocalciferol in adult cystic fibrosis patients. 
  • Disorders of iron metabolism. 
  • Disorders of iron metabolism. 
  • Disorders of iron metabolism. 
  • Duke procedure for super obesity: preliminary report with 3.5-year follow-up. 
  • Effect of bacterial or porcine lipase with low- or high-fat diets on nutrient absorption in pancreatic-insufficient dogs. 
  • Effect of inhalation of coal fly ash on vitamin A distribution in organs of the rat. 
  • Effect of simultaneous didanosine administration on itraconazole absorption in healthy volunteers. 
  • Effects of estrogen/progestin agents on plasma retinoids and chylomicron remnant metabolism. 
  • Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice. 
  • Eventual attenuation of hypocalciuric response to hydrochlorothiazide in absorptive hypercalciuria. 
  • Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. 
  • Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice. 
  • GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats. 
  • Genes that modify the hemochromatosis phenotype in mice. 
  • Hypercalciuria and altered intestinal calcium absorption occurring independently of vitamin D in incomplete distal renal tubular acidosis. 
  • Hypolipidemic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis(trimethylamin e- carboxyborane)-dicopper(II) in rodents and its effect on lipid metabolism. 
  • In vitro and in vivo evaluation of a water-in-oil microemulsion system for enhanced peptide intestinal delivery. 
  • Influence of age on the pharmacokinetics and pharmacodynamics of oral transmucosal fentanyl citrate. 
  • Intestinal iron absorption: current concepts circa 2000. 
  • Iron homeostasis. 
  • Iron metabolism: iron deficiency and iron overload. 
  • Liposomal amphotericin B: clinical experience and perspectives. 
  • Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut. 
  • Metabolism and transport of galactose by rat intestine. 
  • Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir. 
  • Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish. 
  • Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock. 
  • Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection. 
  • Quinidine as a probe for the role of p-glycoprotein in the intestinal absorption and clinical effects of fentanyl. 
  • Recent advances in disorders of iron metabolism: mutations, mechanisms and modifiers. 
  • Regulation of iron absorption in Hfe mutant mice. 
  • Results of bariatric surgery. 
  • Robotically handled whole-tissue culture system for the screening of oral drug formulations. 
  • Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine. 
  • Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats. 
  • Role of the microvillus in the absorption of disaccharides. 
  • Short-chain alkyl esters of L-dopa as prodrugs for rectal absorption. 
  • Small-bowel malabsorption and gastrointestinal malignancy. 
  • Synthesis and evaluation of compounds that facilitate the gastrointestinal absorption of heparin. 
  • Synthesis of C3 heteroatom-substituted azetidinones that display potent cholesterol absorption inhibitory activity. 
  • The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine. 
  • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. 
  • The absorption of oleic acid from emulsion and micellar solution. 
  • The absorption of tristearin and stearic acid and tripalmitin and palmitic acid. Studies on the rate-limiting steps in rats. 
  • The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone. 
  • The intestinal glucose-apelin cycle controls carbohydrate absorption in mice. 
  • The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. 
  • The molecular regulation of iron metabolism. 
  • The regulation of the lymphatic secretion of glucagon-like peptide-1 (GLP-1) by intestinal absorption of fat and carbohydrate. 
  • The role of duodenal cytochrome b in intestinal iron absorption remains unclear. 
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system. 
  • Transplantation of the entire small bowel in inbred rats using cyclosporine. 
  • Understanding heme transport. 
  • Use of fluconazole in a patient with documented malabsorption of ketoconazole. 
  • Use of ketoconazole to probe the pathogenetic importance of 1,25-dihydroxyvitamin D in absorptive hypercalciuria. 
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  Keywords of People

  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Integrative Immunobiology