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Subject Areas on Research
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28-day toxicology test: indenopyridine RTI 4587-056 in male Sprague-Dawley rats.
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A 25-year experience with postresection short-bowel syndrome secondary to radiation therapy.
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A Neural Circuit for Gut-Induced Reward.
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A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities.
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A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.
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A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity.
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A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolites.
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A mathematical model to evaluate the routine use of fecal microbiota transplantation to prevent incident and recurrent Clostridium difficile infection.
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A mouse model of juvenile hemochromatosis.
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A multidisciplinary approach to the treatment of intestinal failure.
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A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation.
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Adenine nucleotides of ischemic intestine do not reflect injury.
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Analysis of results of radiation therapy for stage IB carcinoma of the cervix.
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Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2.
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Aquacultured rainbow trout (Oncorhynchus mykiss) possess a large core intestinal microbiota that is resistant to variation in diet and rearing density.
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Ascaris suum, an intestinal parasite, produces morphine.
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Assessment of quality of life after pediatric intestinal transplantation by parents and pediatric recipients using the child health questionnaire.
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Atypical presentation of inflammatory bowel disease in the elderly.
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Autologous gastrointestinal reconstruction: review of the optimal nontransplant surgical options for adults and children with short bowel syndrome.
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B cells contribute to ischemia/reperfusion-mediated tissue injury.
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Basiliximab decreases the incidence of acute rejection after intestinal transplantation.
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Bi-directionality of Brain-Gut Interactions in Patients With Inflammatory Bowel Disease.
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Blocking Cyclin-Dependent Kinase 4/6 During Single Dose Versus Fractionated Radiation Therapy Leads to Opposite Effects on Acute Gastrointestinal Toxicity in Mice.
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Bmp signaling is required for intestinal growth and morphogenesis.
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CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells.
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Caenorhabditis elegans beta-G spectrin is dispensable for establishment of epithelial polarity, but essential for muscular and neuronal function.
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Campath-1H in intestinal and multivisceral transplantation: preliminary data.
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Can Glycine Mitigate COVID-19 Associated Tissue Damage and Cytokine Storm?
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Caspase-7 activates ASM to repair gasdermin and perforin pores.
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Cell biology: A guardian angel of cell integrity.
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Cellular Sites and Mechanisms Linking Reduction of Dipeptidyl Peptidase-4 Activity to Control of Incretin Hormone Action and Glucose Homeostasis.
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Characterization of a human plasma membrane heme transporter in intestinal and hepatocyte cell lines.
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Combination regimens with statin, niacin, and intestinally active LDL-lowering drugs: alternatives to high-dose statin therapy?
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Comparison of fecal biota from specific pathogen free and feral mice.
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Comparison of short bowel syndrome acquired early in life and during adolescence.
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Comparison of the intestinal and serum antibody response in patients with dermatitis herpetiformis.
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Complex drug interactions of HIV protease inhibitors 1: inactivation, induction, and inhibition of cytochrome P450 3A by ritonavir or nelfinavir.
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Conserved roles for Hnf4 family transcription factors in zebrafish development and intestinal function.
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Contribution of neutral processes to the assembly of gut microbial communities in the zebrafish over host development.
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Control of ingestion in 6-day-old rat pups: termination of intake by gastric fill alone?
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Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge.
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Corroborating evidence refutes batch effect as explanation for fetal bacteria.
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Cost and quality of life after intestinal transplantation.
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Cytoplasmic sharing through apical membrane remodeling.
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Debromination of polybrominated diphenyl ether-99 (BDE-99) in carp (Cyprinus carpio) microflora and microsomes.
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Deciphering the tête-à-tête between the microbiota and the immune system.
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Decompression sickness risk reduced by native intestinal flora in pigs after H2 dives.
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Degeneration of the central nervous system associated with celiac disease.
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Detection of intestinal dysplasia using angle-resolved low coherence interferometry.
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Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis.
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Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice.
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Disaccharidase activities and fat assimilation in pediatric patients after intestinal transplantation.
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Distal ventriculoperitoneal shunt failure secondary to Clostridium difficile colitis.
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Does the intestinal microflora synthesize pyrroloquinoline quinone?
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Effects of dietary pectin and cellulose on hepatic and intestinal mixed-function oxidations and hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the rat.
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Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus.
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Electrical stimulation of the conus medullaris to control the bladder in the paraplegic patient. A 10-year review.
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Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif.
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Engineering Microbiomes-Looking Ahead.
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Enteric conversion of bladder-drained pancreas allografts: experience in 95 patients.
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Enteroaggregative Escherichia coli Subclinical Infection and Coinfections and Impaired Child Growth in the MAL-ED Cohort Study.
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Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice.
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Epidermal growth factor receptor expression and signaling are essential in glutamine's cytoprotective mechanism in heat-stressed intestinal epithelial-6 cells.
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Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells.
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Estimation of liver and intestine lipids of rat by silicic acid column chromatography.
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Evaluating outcomes of enterocystoplasty in patients with spina bifida: a review of the literature.
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Evidence for a core gut microbiota in the zebrafish.
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Experience with the duodenal switch operation in the presence of intestinal malrotation.
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Experiences with bladder reconstruction in children.
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Expression of functional domains of beta G-spectrin disrupts epithelial morphology in cultured cells.
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Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid.
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Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice.
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Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy.
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Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.
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Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine.
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Gastrointestinal dysfunction in the critically ill: nutritional implications.
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General Anesthesia Alters the Diversity and Composition of the Intestinal Microbiota in Mice.
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Genetic control of single lumen formation in the zebrafish gut.
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Genetically induced microtubule disruption in the mouse intestine impairs intracellular organization and transport.
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Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses.
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Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis.
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Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans.
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Glutamine prevents apoptosis in intestinal epithelial cells and induces differential protective pathways in heat and oxidant injury models.
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Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota.
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Gross intestinal morphometry and allometry in primates.
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Gross intestinal morphometry and allometry in ruminants.
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Growth of Intestinal Neomucosa on Pedicled Gastric Wall Flap, a Novel Technique in an Animal Model.
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Gut flora-based therapy in liver disease? The liver cares about the gut.
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Gut immune maturation depends on colonization with a host-specific microbiota.
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Gut microbes out of control in HIV infection.
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Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway.
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HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies.
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Helminth-induced reprogramming of the stem cell compartment inhibits type 2 immunity.
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Hemochromatosis drives acute lethal intestinal responses to hyperyersiniabactin-producing Yersinia pseudotuberculosis.
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High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
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Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation.
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Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.
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Human syngeneic intestinal transplantation: evaluation of enterocyte viability with serum levels of intestinal fatty acid binding protein.
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Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm.
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IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria.
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IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis.
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IL-10-producing regulatory B10 cells inhibit intestinal injury in a mouse model.
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Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties.
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Immunofluorescence localization of an adducin-like protein in the chromosomes of mouse oocytes.
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Implication of gut microbiota in nonalcoholic fatty liver disease.
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In vivo imaging and genetic analysis link bacterial motility and symbiosis in the zebrafish gut.
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Increased loss of CCR5+ CD45RA- CD4+ T cells in CD8+ lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeys.
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Inflammasome, Inflammation, and Tissue Homeostasis.
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Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88.
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Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate.
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Inhibition of cholesterol transport in an intestine cell model by pine-derived phytosterols.
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Inhibition of gastric emptying in response to intestinal lipid is dependent on chylomicron formation.
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Initial experience using rapamycin immunosuppression in pediatric intestinal transplant recipients.
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Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism.
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Insulin-like signalling to the maternal germline controls progeny response to osmotic stress.
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Interaction of ethanol and acute hypoxia (7620 m) on vitamin A distribution in rat organs.
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Interorgan regulation of Drosophila intestinal stem cell proliferation by a hybrid organ boundary zone.
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Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice.
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Intestinal Inflammation Promotes MDL-1+ Osteoclast Precursor Expansion to Trigger Osteoclastogenesis and Bone Loss.
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Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia.
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Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization.
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Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates.
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Intestinal and hepatic complications of human bone marrow transplantation. Part II.
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Intestinal ischemia-reperfusion injury causes pulmonary endothelial cell ATP depletion.
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Intestinal lengthening for short bowel syndrome.
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Intestinal lengthening in adult patients with short bowel syndrome.
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Intestinal malrotation in neonates with nonbilious emesis.
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Intestinal mast cells mediate gut injury and systemic inflammation in a rat model of deep hypothermic circulatory arrest.
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Intestinal mucin is a chaperone of multivalent copper.
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Intestinal permeability and inflammation mediate the association between nutrient density of complementary foods and biochemical measures of micronutrient status in young children: results from the MAL-ED study.
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Intestinal transplantation: a single-center experience.
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Intestinal transplantation: the University of Wisconsin experience.
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Intestine Transplantation Across a Positive Crossmatch With Preformed Donor-Specific Antibodies.
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Irritable Bowel Syndrome: Pathophysiology and Current Therapeutic Approaches.
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Isolated intestinal transplantation for intestinal failure.
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L-Threonine induces heat shock protein expression and decreases apoptosis in heat-stressed intestinal epithelial cells.
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Lack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A).
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Lack of utility of intestinal fatty acid binding protein levels in predicting intestinal allograft rejection.
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Lactobacillus rhamnosus GG treatment improves intestinal permeability and modulates inflammatory response and homeostasis of spleen and colon in experimental model of Pseudomonas aeruginosa pneumonia.
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Lactose drives Enterococcus expansion to promote graft-versus-host disease.
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Late graft loss and long-term outcome after isolated intestinal transplantation in children.
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Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain.
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Liver and intestine transplantation in the United States 1998-2007.
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Liver and intestine transplantation in the United States, 1997-2006.
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Long-term outcomes and quality of life after intestine transplantation.
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Long-term results of intestinal transplantation for pseudo-obstruction in children.
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Low Cost Gastroschisis Silo for Sub-Saharan Africa: Testing in a Porcine Model.
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Lubiprostone Is Effective in Treating Functional Bowel Disease With Constipation.
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Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut.
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Magnamosis: magnetic compression anastomosis with comparison to suture and staple techniques.
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Magnetic Compression Anastomosis (Magnamosis) for Functional Undiversion of Ileostomy in Pediatric Patients.
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Magnetic resonance imaging for detection of arterial and venous occlusion in canine muscle flaps and bowel segments.
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Mammalian intestinal allometry, phylogeny, trophic level and climate.
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Management of the bladder outlet in patients requiring enterocystoplasty.
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Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.
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Melphalan-induced toxicity in nude mice following pretreatment with buthionine sulfoximine.
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Metabolic Teamwork in the Stem Cell Niche.
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Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): potential contribution of intestinal metabolism to presystemic clearance and bioactivation.
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Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function.
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Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract.
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Microbiota and the gut-liver axis: bacterial translocation, inflammation and infection in cirrhosis.
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Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish.
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Modulation of decompression sickness risk in pigs with caffeine during H(2) biochemical decompression.
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Modulation of intestinal sulfur assimilation metabolism regulates iron homeostasis.
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Molecular basis for the enterocyte tropism exhibited by Salmonella typhimurium type 1 fimbriae.
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Monoclonal antibodies to the common gamma-chain as cytokine receptor antagonists in vivo: effect on intrathymic and intestinal intraepithelial T lymphocyte development.
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Morphogenesis and Compartmentalization of the Intestinal Crypt.
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Moving beyond microbiome-wide associations to causal microbe identification.
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NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma.
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NK cell recruitment limits tissue damage during an enteric helminth infection.
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Natural history of pediatric intestinal failure: initial report from the Pediatric Intestinal Failure Consortium.
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Non-alcoholic fatty liver disease: lumen-liver interactions and possible role for probiotics.
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Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis.
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Novel mechanism of rapamycin in GVHD: increase in interstitial regulatory T cells.
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Nutrient tasting and signaling mechanisms in the gut. IV. There is more to taste than meets the tongue.
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Omeprozole therapy in pediatric patients after liver and intestinal transplantation.
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On the likelihood of decompression sickness during H(2) biochemical decompression in pigs.
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Organ uptake and release of inorganic nitrate and nitrite in the pig.
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P38MAP kinase, but not phosphoinositol-3 kinase, signal downstream of glutamine-mediated fibronectin-integrin signaling after intestinal injury.
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PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo.
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Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock.
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Pathologic features of enteric infection with Yersinia enterocolitica.
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Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas.
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Physiology, Development, and Disease Modeling in the Drosophila Excretory System.
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Pneumatosis intestinalis. Surgical management and clinical outcome.
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Postoperative short bowel syndrome.
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Posttransplant infection in enteric versus bladder-drained simultaneous pancreas-kidney transplant recipients.
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Predicting outcome of procedures to slow intestinal transit.
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Predictors of Enteral Autonomy in Children with Intestinal Failure: A Multicenter Cohort Study.
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Pregnancy with prolonged fetal exposure to an angiotensin-converting enzyme inhibitor.
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Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption, and improving recovery of bowel function in patients undergoing colorectal cancer surgery.
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Prenatal ultrasonographic findings associated with short bowel syndrome in two fetuses with gastroschisis.
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Promotion of the development of enteric neurons and glia by neuropoietic cytokines: interactions with neurotrophin-3.
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Prospective evaluation of Peristeen® transanal irrigation system with the validated neurogenic bowel dysfunction score sheet in the pediatric population.
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Pulmonary endothelial cell ATP depletion following intestinal ischemia.
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Quality of life after intestinal transplantation.
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Quality of life after pediatric intestinal transplantation: the perception of pediatric recipients and their parents.
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Race affects outcome among infants with intestinal failure.
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Rapid changes in the gut microbiome during human evolution.
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Regulation of cholecystokinin synthesis and secretion in rat intestine.
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Regulation of expression of transcobalamin II receptor in the rat.
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Regulation of intestinal cholecystokinin and somatostatin mRNA by bombesin in rats.
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Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification.
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Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates.
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Results of solitary pancreas transplantation with enteric drainage: is there a benefit from monitoring urinary amylase levels?
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Role of an intestinal rehabilitation program in the treatment of advanced intestinal failure.
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Role of murine intestinal interleukin-1 receptor 1-expressing lymphoid tissue inducer-like cells in Salmonella infection.
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Role of platelet activating factor in the inflammatory and secretory effects of Clostridium difficile toxin A.
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Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease.
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Sensitization of Vascular Endothelial Cells to Ionizing Radiation Promotes the Development of Delayed Intestinal Injury in Mice.
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Short bowel syndrome after laparoscopic procedures.
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Short bowel syndrome after trauma.
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Short bowel syndrome following bariatric surgical procedures.
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Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats.
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Starvation causes changes in the intestinal transcriptome and microbiome that are reversed upon refeeding.
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Stem Cell-Derived Models of Viral Infections in the Gastrointestinal Tract.
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Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts.
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Studies on the epidemiology of antibiotic-associated Clostridium difficile colitis.
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Study of host-microbe interactions in zebrafish.
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Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors.
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Swim exercise in Caenorhabditis elegans extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegeneration.
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Swirl Sign - Intestinal Volvulus after Roux-en-Y Gastric Bypass.
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Terry Lechler: the cytoskeleton is skin deep. Interview by Nicole LeBrasseur.
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The Caenorhabditis elegans ABL-1 tyrosine kinase is required for Shigella flexneri pathogenesis.
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The Mycobacterium tuberculosis 71-kDa heat-shock protein induces proliferation and cytokine secretion by murine gut intraepithelial lymphocytes.
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The Skin and Intestinal Microbiota and Their Specific Innate Immune Systems.
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The composition of the zebrafish intestinal microbial community varies across development.
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The intestinal lymph fistula model--a novel approach to study ghrelin secretion.
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The intestinal tuft cell nanostructure in 3D.
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The intestine is a major contributor to circulating succinate in mice.
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The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut.
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The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila.
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The structure of a molybdopterin precursor. Characterization of a stable, oxidized derivative.
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The yin yang of bacterial polysaccharides: lessons learned from B. fragilis PSA.
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Thresholds for thermal damage to normal tissues: an update.
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Tissue-specific migration pathways by phenotypically distinct subpopulations of memory T cells.
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Total parenteral nutrition-related gastroenterological complications.
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Toxic effect of the roasted and unroasted beans of Cassia occidentalis in goats.
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Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.
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Transcriptional programmes underlying cellular identity and microbial responsiveness in the intestinal epithelium.
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Transcriptomics integrated with metabolomics reveals the effect of Bisphenol F (BPF) exposure on intestinal inflammation.
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Treatment of intestinal failure: intestinal transplantation.
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Urinary diversion in the genitourinary cancer survivor.
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Use of Everolimus After Multivisceral Transplantation: A Report of Two Cases.
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Use of L-glutamine in total parenteral nutrition.
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Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose.
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Viable bacterial colonization is highly limited in the human intestine in utero.
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Viscera affectum anno: the gut beyond eating behaviours.
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Volumetric arc intensity-modulated therapy for spine body radiotherapy: comparison with static intensity-modulated treatment.
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[A case of congenital malabsorption of lactose].
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c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
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mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium.
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n-3 Canola oil effectively replaces fish oil as a new safe dietary source of DHA in feed for juvenile Atlantic salmon.
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βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1.
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Keywords of People
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Bradford, William Dalton,
Professor of Pathology,
Pathology
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Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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Karhausen, Jorn,
Adjunct Associate Professor in the Department of Anesthesiology,
Anesthesiology, Cardiothoracic
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Wax, Adam P.,
Professor of Biomedical Engineering,
Biomedical Engineering