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Subject Areas on Research
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1-(m-[211At]astatobenzyl)guanidine: synthesis via astato demetalation and preliminary in vitro and in vivo evaluation.
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125I embedded in an orbital prosthesis for retreatment of recurrent retinoblastoma.
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125I-labeled anti-epidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts.
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131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment.
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211At- and 131I-labeled bisphosphonates with high in vivo stability and bone accumulation.
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3-[211At]astato-4-fluorobenzylguanidine: a potential therapeutic agent with prolonged retention by neuroblastoma cells.
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5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.
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A controlled trial of two low-dose heparin regimens for the prevention of postoperative deep vein thrombosis.
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A method for the radiohalogenation of proteins resulting in decreased thyroid uptake of radioiodine.
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A phase II study of external beam radiotherapy combined with permanent source brachytherapy for intermediate-risk, clinically localized adenocarcinoma of the prostate: preliminary results of RTOG P-0019.
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A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost.
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A polar substituent-containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB).
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A procedure for the preferential radioiodination of small amounts of protein in the presence of excess lipids.
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A prospective quality-of-life study in men with clinically localized prostate carcinoma treated with radical prostatectomy, external beam radiotherapy, or interstitial brachytherapy.
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A radioiodinated MIBG-octreotate conjugate exhibiting enhanced uptake and retention in SSTR2-expressing tumor cells.
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ACTH receptors in the adrenal: specific binding of ACTH-125I and its relation to adenyl cyclase.
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Abnormalities of cardiac sympathetic function in pacing-induced heart failure as assessed by [123I]metaiodobenzylguanidine scintigraphy.
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Abundant tyrosine residues in the antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Application to radiolabeling.
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Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein.
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Acute urinary toxicity following transperineal prostate brachytherapy using a modified Quimby loading method.
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Adenosine triphosphate activates ion permeabilities in biliary epithelial cells.
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Adequacy of Lymph Node Yield for Papillary Thyroid Cancer: An Analysis of 23,131 Patients.
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Adjuvant radioactive iodine therapy is associated with improved survival for patients with intermediate-risk papillary thyroid cancer.
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Adrenergic receptors in premenstrual dysphoric disorder. II. Neutrophil beta2-adrenergic receptors: Gs protein coupling, phase of menstrual cycle and prediction of luteal phase symptom severity.
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Adrenergic receptors.
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Aggressive variants of papillary thyroid cancer: incidence, characteristics and predictors of survival among 43,738 patients.
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Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts.
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An alternative and expedient synthesis of radioiodinated 4-iodophenylalanine.
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Angiotensinogen synthesis in the liver is independent of physiological estrogen levels.
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Antidepressant effects of nicotine in an animal model of depression.
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Antiepidermal growth factor variant III scFv fragment: effect of radioiodination method on tumor targeting and normal tissue clearance.
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Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma.
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Association between ankyrin and the cytoplasmic domain of band 3 isolated from the human erythrocyte membrane.
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Association between human erythrocyte calmodulin and the cytoplasmic surface of human erythrocyte membranes.
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Association of brain ankyrin with brain membranes and isolation of active proteolytic fragments of membrane-associated ankyrin-binding protein(s).
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Autodegradation of 125I-labeled human epidermal cell surface proteins.
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Binding of native and reduced and carbamidomethylated hGH to rabbit liver plasma membranes.
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Binding of purified and radioiodinated capsular polysaccharides from Cryptococcus neoformans serotype A strains to capsule-free mutants.
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Biologically effective dose (BED) correlation with biochemical control after low-dose rate prostate brachytherapy for clinically low-risk prostate cancer.
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Blocking [211At]astatide accumulation in normal tissues: preliminary evaluation of seven potential compounds.
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Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ.
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Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours.
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Brain phantom: high-resolution imaging with SPECT and I-123.
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Captopril renography in the diagnosis of renovascular disease.
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Carbohydrate recognition systems in amphibians: primitive alpha 2-macroglobulin receptors.
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Carcinoid tumors: iodine-131 MIBG scintigraphy.
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Cardiac cryosurgery: regional myocardial blood flow of ventricular cryolesions.
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Carrier-free 131I-meta-iodobenzylguanidine: comparison of production from meta-diazobenzylguanidine and from meta-trimethylsilylbenzylguanidine.
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Catabolism of radioiodinated murine monoclonal antibody F(ab')2 fragment labeled using N-succinimidyl 3-iodobenzoate and Iodogen methods.
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Catabolism of streptokinase and polyethylene glycol-streptokinase: evidence for transport of intact forms through the biliary system in the mouse.
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Cellular uptake and processing of surfactant lipids and apoprotein SP-A by rat lung.
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Characterization of a rat type 2 angiotensin II receptor stably expressed in 293 cells.
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Characterization of angiotensin II-receptor subtypes in podocytes.
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Characterization of liposomes containing iodine-125-labeled radiographic contrast agents.
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Chimeric anti-tenascin antibody 81C6: increased tumor localization compared with its murine parent.
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Cholera toxin and cell growth: role of membrane gangliosides.
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Circulating IgA immune complexes in patients with psoriasis.
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Clinical review 99: The management of Graves' disease in children, with special emphasis on radioiodine treatment.
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Clinical studies on the radioimmunodetection of tumors containing alpha-fetoprotein.
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Combination external beam radiation and brachytherapy boost with androgen suppression for treatment of intermediate-risk prostate cancer: an initial report of CALGB 99809.
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Comparative tissue distribution in mice of the alpha-emitter 211At and 131I as labels of a monoclonal antibody and F(ab')2 fragment.
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Comparison of [125I]HIPDm and [125I]iodoantipyrine in quantifying regional cerebral blood flow in rats.
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Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies.
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Comparison of radical prostatectomy and iodine 125 interstitial radiotherapy for the treatment of clinically localized prostate cancer: a 7-year biochemical (PSA) progression analysis.
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Comparison of radiohaloanalogues of meta-iodobenzylguanidine (MIBG) for a combined gene- and targeted radiotherapy approach to bladder carcinoma.
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Comparison of various methods for delivering radiolabeled monoclonal antibody to normal rat brain.
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Comparison of ¹²³I-metaiodobenzylguanidine (MIBG) and ¹³¹I-MIBG semi-quantitative scores in predicting survival in patients with stage 4 neuroblastoma: a report from the Children's Oncology Group.
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Covalent labeling of the beta-adrenergic ligand-binding site with para-(bromoacetamidyl)benzylcarazolol. A highly potent beta-adrenergic affinity label.
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Cytotoxicity of alpha-particle-emitting 5-[211At]astato-2'-deoxyuridine in human cancer cells.
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D-Amino acid peptide residualizing agents bearing N-hydroxysuccinimido- and maleimido-functional groups and their application for trastuzumab radioiodination.
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Design, synthesis, and functional assessment of Cmpd-15 derivatives as negative allosteric modulators for the β2-adrenergic receptor.
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Detection of oncornavirus antigenic activity in human urothelial tissues.
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Development and characterization of a monoclonal antibody to human embryonal carcinoma.
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Development of a fluorescent ligand-binding assay using the AcroWell filter plate.
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Development of a radioimmunoassay for fetal antigen 2.
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Developmental regulation of insulin-like growth factor binding protein production: studies in fetal, postnatal, and pregnant sheep.
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Differential localization of cholecystokinin-8 binding sites in the rat vs. the guinea pig brain.
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Differential solubilization of placental lactogen (PL)- and growth hormone-binding sites: further evidence for a unique PL receptor in fetal and maternal liver.
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Distribution and dosimetry of I-123-labeled monoclonal antibody 81C6 in patients with anaplastic glioma.
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Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts.
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Domains of the parathyroid hormone (PTH) receptor required for regulation by G protein-coupled receptor kinases (GRKs).
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Dosimetric quantifiers for low-dose-rate prostate brachytherapy: is V(100) superior to D(90)?
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Dosimetry and cancer control after low-dose-rate prostate brachytherapy.
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Dosimetry and dose-response relationships in newly diagnosed patients with malignant gliomas treated with iodine-131-labeled anti-tenascin monoclonal antibody 81C6 therapy.
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Dosimetry and radiographic analysis of 131I-labeled anti-tenascin 81C6 murine monoclonal antibody in newly diagnosed patients with malignant gliomas: a phase II study.
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Dosimetry of 131I-labeled 81C6 monoclonal antibody administered into surgically created resection cavities in patients with malignant brain tumors.
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Down regulation of macrophage mannose/N-acetylglucosamine receptors by elevated glucose concentrations.
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Early macular morphological changes following plaque radiotherapy for uveal melanoma.
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Editorial comment.
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Effect of fibronectin amount and conformation on the strength of endothelial cell adhesion to HEMA/EMA copolymers.
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Effect of radioiodination on the binding of monoclonal antibody DF3 to breast carcinoma cells.
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Effects of calcium on ACTH stimulation of the adrenal: separation of hormone binding from adenyl cyclase activation.
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Effects of characteristic x-rays on assay of I-123 by dose calibrator.
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Effects of fetal dexamethasone exposure on postnatal control of cardiac adenylate cyclase: beta-adrenergic receptor coupling to Gs regulatory protein.
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Effects of insulin-like growth factors I and II and insulin on the immortalized hypothalamic GTI-7 cell line.
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Effects of specific activity on meta-[(131)I]iodobenzylguanidine kinetics in isolated rat heart.
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Efficacy and Safety of Low-Dose Iodine Plaque Brachytherapy for Juxtapapillary Choroidal Melanoma.
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Enhanced binding and inertness to dehalogenation of alpha-melanotropic peptides labeled using N-succinimidyl 3-iodobenzoate.
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Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia.
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Enhanced tumor localization and in vivo stability of a monoclonal antibody radioiodinated using N-succinimidyl 3-(tri-n-butylstannyl)benzoate.
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Enhanced tumour uptake and in vitro radiotoxicity of no-carrier-added [131I]meta-iodobenzylguanidine: implications for the targeted radiotherapy of neuroblastoma.
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Enhanced tumour uptake of radiolabelled antibodies by hyperthermia. Part II: Application of the thermal equivalency equation.
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Enhanced tumour uptake of radiolabelled antibodies by hyperthermia: Part I: Timing of injection relative to hyperthermia.
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Enzyme occupancy measurement of intracellular protein tyrosine phosphatase 1B using photoaffinity probes.
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Equivalent uniform dose, D(90), and V(100) correlation with biochemical control after low-dose-rate prostate brachytherapy for clinically low-risk prostate cancer.
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Evaluation of an 131I-labeled HER2-specific single domain antibody fragment for the radiopharmaceutical therapy of HER2-expressing cancers.
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Evaluation of an anti-p185(HER2) (scFv-C(H)2-C(H)3)2 fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-D-GEEEK.
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Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas.
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Evaluation of meta-[211At]astatobenzylguanidine in an athymic mouse human neuroblastoma xenograft model.
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Fabrication and testing of a device capable of reducing the incidence of ventricular shunt promoted metastasis.
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Failure to visualize experimentally produced emboli and thrombi using 131I streptokinase.
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Ferromagnetic hyperthermia and iodine 125 brachytherapy in the treatment of choroidal melanoma in a rabbit model.
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First reported case of unilateral Graves' disease in the left lobe of a bilobar thyroid gland.
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Fluorine-18-labeled [Nle4,D-Phe7]-alpha-MSH, an alpha-melanocyte stimulating hormone analogue.
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Future alternatives to heparin: low-molecular-weight heparin and hirudin.
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Gastrointestinal toxicity of transperineal interstitial prostate brachytherapy.
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Growth factor receptors as molecular targets for cancer diagnosis and therapy.
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Health physics consequences of out-patient treatment of non-Hodgkin's lymphoma with 131I-radiolabeled anti-B1 antibody.
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Health-related quality of life in men receiving prostate brachytherapy on RTOG 98-05.
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Hematologic toxicity of high-dose iodine-131-metaiodobenzylguanidine therapy for advanced neuroblastoma.
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Hepatocyte uptake of alpha 1-proteinase inhibitor-trypsin complexes in vitro: evidence for a shared uptake mechanism for proteinase complexes of alpha 1-proteinase inhibitor and antithrombin III.
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Human IgG2 constant region enhances in vivo stability of anti-tenascin antibody 81C6 compared with its murine parent.
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Human melanoma and leukemia associated antigens difined by nonhuman primate antisera.
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Human/murine chimeric 81C6 F(ab')(2) fragment: preclinical evaluation of a potential construct for the targeted radiotherapy of malignant glioma.
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Hyperthermic modulation of radiolabelled antibody uptake in a human glioma xenograft and normal tissues.
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Hypoparathyroidism after I-131 therapy with subsequent return of parathyroid function.
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I-131, I-123, and F-18 FDG-PET imaging in a patient with diffuse sclerosing variant of papillary thyroid cancer.
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INITIAL ADOPTION OF RECOMBINANT HUMAN THYROID-STIMULATING HORMONE FOLLOWING THYROIDECTOMY IN THE MEDICARE THYROID CANCER PATIENT POPULATION.
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Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe.
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Immunodiagnosis of tumors in vivo using radiolabeled monoclonal antibody A2B5.
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Immunoreactivity, pharmacokinetics and bone marrow dosimetry of intrathecal radioimmunoconjugates.
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Improved therapeutic efficacy of a monoclonal antibody radioiodinated using N-succinimidyl-3-(tri-n-butylstannyl)benzoate.
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In regards to Wallner et al: (125)I versus (103)PD for low-risk prostate cancer: preliminary PSA outcomes from a prospective randomized multicenter trial (Int J Radiat Oncol Biol Phys 2003;57:1297-1303).
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In vitro and in vivo behavior of radiolabeled chimeric anti-EGFRvIII monoclonal antibody: comparison with its murine parent.
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In vitro cytotoxicity of (211)at-astatide and (131)I-iodide to glioma tumor cells expressing the sodium/iodide symporter.
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In vivo imaging of brain nicotinic acetylcholine receptors with 5-[123I]iodo-A-85380 using single photon emission computed tomography.
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In vivo imaging of intracranial human glioma xenografts comparing specific with nonspecific radiolabeled monoclonal antibodies.
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In vivo lysis of L5178Y cells in the establishment of the tumor-dormant state in DBA/2 mice.
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In vivo quantitation of regional cerebral blood flow in glioma and cerebral infarction: validation of the HIPDm-SPECT method.
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In vivo studies with [125I]5-I-A-85380, a nicotinic acetylcholine receptor radioligand.
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In vivo tumor localization using tumor-specific monkey xenoantibody, alloantibody, and murine monoclonal xenoantibody.
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Incorporating patient-specific CT-based ophthalmic anatomy in modeling iodine-125 eye plaque brachytherapy dose distributions.
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Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII-specific scFv.
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Influence of circulating antigen on blood pool activity of a radioiodinated monoclonal antibody.
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Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy.
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Insular thyroid cancer: a population-level analysis of patient characteristics and predictors of survival.
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Interaction sites of the C-terminal region of the cGMP phosphodiesterase inhibitory subunit with the GDP-bound transducin alpha-subunit.
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Interaction sites of the COOH-terminal region of the gamma subunit of cGMP phosphodiesterase with the GTP-bound alpha subunit of transducin.
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Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United States.
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Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results.
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Intrathecal administration of 131I radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.
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Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot.
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Intravitreal triamcinolone acetonide for acute radiation papillopathy.
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Iodine 131-labeled metaiodobenzylguanidine scintigraphy and biochemical analyses in suspected pheochromocytoma.
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Iodine-123 MIBG imaging before treatment of heart failure with carvedilol to predict improvement of left ventricular function and exercise capacity.
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Iodine-125 interstitial irradiation of virally induced dog brain tumours.
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Iodine-131 metaiodobenzylguanidine treatment for metastatic carcinoid. Results in 98 patients.
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Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results.
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Iodine-131-metaiodobenzylguanidine uptake in metastatic carcinoid tumor to the orbit.
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Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine.
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Knowledge of pathologically versus clinically negative lymph nodes is associated with reduced use of radioactive iodine post-thyroidectomy for low-risk papillary thyroid cancer.
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Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[18F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios.
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Labeling a TCO-functionalized single domain antibody fragment with 18F via inverse electron demand Diels Alder cycloaddition using a fluoronicotinyl moiety-bearing tetrazine derivative.
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Labeling monoclonal antibodies with halogen nuclides.
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Labeling proteins using aryl iodide acylation agents: influence of meta vs para substitution on in vivo stability.
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Large scale purification of factor X by hydrophobic chromatography.
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Localization of I-131-labeled goat and primate anti-carcinoembryonic antigen(CEA) antibodies in patients with cancer.
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Localization of RNA tumor virus polypeptides. I. Isolation of further virus substructures.
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Locally increased uptake of fluorine-18-fluorodeoxyglucose after intracavitary administration of iodine-131-labeled antibody for primary brain tumors.
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Long term response in a patient with neoplastic meningitis secondary to melanoma treated with (131)I-radiolabeled antichondroitin proteoglycan sulfate Mel-14 F(ab')(2): a case study.
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Long-Term Outcomes of 125 Patients With Metastatic Pheochromocytoma or Paraganglioma Treated With 131-I MIBG.
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Long-term results of a phase II trial of ultrasound-guided radioactive implantation of the prostate for definitive management of localized adenocarcinoma of the prostate (RTOG 98-05).
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Long-term results of an RTOG Phase II trial (00-19) of external-beam radiation therapy combined with permanent source brachytherapy for intermediate-risk clinically localized adenocarcinoma of the prostate.
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Low-Risk Thyroid Cancer in Elderly: Total Thyroidectomy/RAI Predominates but Lacks Survival Advantage.
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Lymphovascular invasion is associated with survival for papillary thyroid cancer.
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Measurement and Variation in Estimation of Quality of Life Effects of Patients Undergoing Treatment for Papillary Thyroid Carcinoma.
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Measurement of endothelial permeability to 125I-low density lipoproteins in rabbit arteries by use of en face preparations.
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Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.
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Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.
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Membrane receptors as general markers for plasma membrane isolation procedures. The use of 125-I-labeled wheat germ agglutinin, insulin, and cholera toxin.
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Meta-[131I]iodobenzylguanidine uptake and meta-[211At]astatobenzylguanidine treatment in human medulloblastoma cell lines.
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Meta-iodobenzylguanidine and analogues: chemistry and biology.
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Meta-iodobenzylguanidine derivatives containing a second guanidine moiety.
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Metaiodobenzylguanidine imaging in diabetes mellitus: assessment of cardiac sympathetic denervation and its relation to autonomic dysfunction and silent myocardial ischemia.
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Method for radioiodination of proteins using N-succinimidyl 3-hydroxy-4-iodobenzoate.
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Mineral metabolites and CKD progression in African Americans.
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Minimally invasive follicular carcinoma: predictors of vascular invasion and impact on patterns of care.
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Modular nanotransporters: a multipurpose in vivo working platform for targeted drug delivery.
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Molecular Imaging in the Head and Neck: Diagnosis and Therapy.
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Molecular imaging of alkylguanine-DNA alkyltransferase: further evaluation of radioiodinated derivatives of O6-benzylguanine.
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Monitor peptide binding sites are expressed in the rat liver and small intestine.
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Monoclonal antibodies to tissue-specific cell surface antigens. I. Characterization of an antibody to a prostate tissue antigen.
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Monoclonal antibody F(ab')2 fragment labeled with N-succinimidyl 2,4-dimethoxy-3-halobenzoates: in vivo comparison of iodinated and astatinated fragments.
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Monoclonal antibody and F(ab')2 fragment delivery to tumor in patients with glioma: comparison of intracarotid and intravenous administration.
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Monoclonal antibody localization in subcutaneous and intracranial human glioma xenografts: paired-label and imaging analysis.
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Multi-species prostate implant treatment plans incorporating 192Ir and 125I using a Greedy Heuristic based 3D optimization algorithm.
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Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy.
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N-Succinimidyl guanidinomethyl iodobenzoate protein radiohalogenation agents: influence of isomeric substitution on radiolabeling and target cell residualization.
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N-succinimidyl 3-[(131)I]iodo-4-phosphonomethylbenzoate ([(131)I]SIPMB), a negatively charged substituent-bearing acylation agent for the radioiodination of peptides and mAbs.
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N-succinimidyl 4-methyl-3-(tri-n-butylstannyl)benzoate: synthesis and potential utility for the radioiodination of monoclonal antibodies.
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N-succinimidyl 5-(trialkylstannyl)-3-pyridinecarboxylates: a new class of reagents for protein radioiodination.
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Nearest neighbor analysis for brain synapsin I. Evidence from in vitro reassociation assays for association with membrane protein(s) and the Mr = 68,000 neurofilament subunit.
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Nepsilon-(3-[*I]Iodobenzoyl)-Lys5-Nalpha-maleimido-Gly1-GEEEK ([*I]IB-Mal-D-GEEEK): a radioiodinated prosthetic group containing negatively charged D-glutamates for labeling internalizing monoclonal antibodies.
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Neuroendocrine effects of dehydration in mice lacking the angiotensin AT1a receptor.
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New MIBG preparation to improve targeted radiotherapy and reduce toxic side-effects in neuroblastoma patients undergoing combination treatment.
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New therapeutic options in the management of childhood brain tumors.
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Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin.
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No-carrier-added (4-fluoro-3-[131I]iodobenzyl)guanidine and (3-[211At]astato-4-fluorobenzyl)guanidine.
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No-carrier-added iodine-131-FIBG: evaluation of an MIBG analog.
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No-carrier-added meta-[123I]iodobenzylguanidine: synthesis and preliminary evaluation.
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No-carrier-added synthesis of a 4-methyl-substituted meta-iodobenzylguanidine analogue.
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No-carrier-added synthesis of meta-[131I]iodobenzylguanidine.
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Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe.
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Nutritional regulation of the placental lactogen receptor in fetal liver: implications for fetal metabolism and growth.
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O6-3-[125I]iodobenzyl-2'-deoxyguanosine ([125I]IBdG): synthesis and evaluation of its usefulness as an agent for quantification of alkylguanine-DNA alkyltransferase (AGT).
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O6-3-[131I]iodobenzylguanine: improved synthesis and further evaluation of a potential agent for imaging of alkylguanine-DNA alkyltransferase.
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Observations on the Effects of Residualization and Dehalogenation on the Utility of N-Succinimidyl Ester Acylation Agents for Radioiodination of the Internalizing Antibody Trastuzumab.
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On the feasibility of polyurethane based 3D dosimeters with optical CT for dosimetric verification of low energy photon brachytherapy seeds.
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Oncornavirus-like protein expression in human prostatic tissue.
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Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.
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Organ distribution of Corynebacterium parvum labeled with iodine-125.
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Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors.
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PDGF-stimulated fibroblast proliferation is enhanced synergistically by receptor-recognized alpha 2-macroglobulin.
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Painful acute radiation thyroiditis induced by 131I treatment of Graves' disease.
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Patterns of use and cost for inappropriate radioactive iodine treatment for thyroid cancer in the United States: use and misuse.
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Periocular triamcinolone for prevention of macular edema after iodine 125 plaque radiotherapy of uveal melanoma.
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Periocular triamcinolone for prevention of macular edema after plaque radiotherapy of uveal melanoma: a randomized controlled trial.
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Permanent source brachytherapy for prostate cancer. American College of Radiology. ACR Appropriateness Criteria.
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Pharmacodynamics of basic fibroblast growth factor: route of administration determines myocardial and systemic distribution.
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Pharmacokinetics and tumor localization of 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies.
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Pharmacokinetics of a radioiodinated monoclonal antibody F(ab')2 fragment in a xenograft model with circulating antigen.
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Pharmacokinetics of radiolabeled monoclonal antibody B6.2 in patients with metastatic breast cancer.
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Phase 1 trial study of 131I-labeled chimeric 81C6 monoclonal antibody for the treatment of patients with non-Hodgkin lymphoma.
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Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab')2--a preliminary report.
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Phase II study on the effect of disease sites, age, and prior therapy on response to iodine-131-metaiodobenzylguanidine therapy in refractory neuroblastoma.
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Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas.
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Phase-1 clinical trial results of high-specific-activity carrier-free 123I-iobenguane.
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Photoaffinity cross-linking of a radioiodinated probe, 125I-A55453, into alpha 1-adrenergic receptors.
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Photoaffinity labeling of mammalian alpha 1-adrenergic receptors. Identification of the ligand binding subunit with a high affinity radioiodinated probe.
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Polyethylene glycol modification of serpins improves therapeutic potential.
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Positively charged templates for labeling internalizing antibodies: comparison of N-succinimidyl 5-iodo-3-pyridinecarboxylate and the D-amino acid peptide KRYRR.
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Postimplant analysis of transperineal interstitial permanent prostate brachytherapy: evidence for a learning curve in the first year at a single institution.
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Postoperative Surveillance in Older Adults With T1N0M0 Low-risk Papillary Thyroid Cancer.
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Preclinical Development of [211At]meta- astatobenzylguanidine ([211At]MABG) as an Alpha Particle Radiopharmaceutical Therapy for Neuroblastoma.
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Predictors of Survival in 211 Patients with Stage IV Pulmonary and Gastroenteropancreatic MIBG-Positive Neuroendocrine Tumors Treated with 131I-MIBG.
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Preparation and biological evaluation of an astatine-211 labeled biotin conjugate: biotinyl-3-[211 At]astatoanilide.
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Preparation and characterization of anti-tenascin monoclonal antibody-streptavidin conjugates for pretargeting applications.
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Preparation and preliminary evaluation of 4-[211At]astato-N-piperidinoethyl benzamide.
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Preparation of 5-[131I]iodo- and 5-[211At]astato-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil by a halodestannylation reaction.
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Preparation of N-succinimidyl 3-[*I]iodobenzoate: an agent for the indirect radioiodination of proteins.
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Prognostic significance of amino acid transport imaging in patients with brain tumors.
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Prolonged exercise alters beta-adrenergic responsiveness in healthy sedentary humans.
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Prostate brachytherapy: a descriptive analysis from CaPSURE.
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Protein radiohalogenation: observations on the design of N-succinimidyl ester acylation agents.
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Quantitative SPECT reconstruction of iodine-123 data.
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Quantitative imaging of iodine-131 distributions in brain tumors with pinhole SPECT: a phantom study.
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Radioactive Iodine Treatment Is Associated with Improved Survival for Patients with Hürthle Cell Carcinoma.
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Radioactive sources embedded in suture are associated with improved postimplant dosimetry in men treated with prostate brachytherapy.
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Radiohalogenation of a monoclonal antibody using an N-succinimidyl 3-(tri-n-butylstannyl)benzoate intermediate.
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Radioimmunotargeting of malignant glioma by monoclonal antibody D2C7 reactive against both wild-type and variant III mutant epidermal growth factor receptors.
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Radioimmunotherapy of breast cancer xenografts with monoclonal antibody ICR12 against c-erbB2 p185: comparison of iodogen and N-succinimidyl 4-methyl-3-(tri-n-butylstannyl)benzoate radioiodination methods.
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Radioimmunotherapy of intracerebral human glioma xenografts with 131I-labeled F(ab')2 fragments of monoclonal antibody Mel-14.
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Radioiodinated B6.2 monoclonal antibody: further characterization of a potential radiopharmaceutical for the identification of breast tumors.
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Radioiodinated O(6)-Benzylguanine derivatives containing an azido function.
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Radioiodinated antibody targeting of the HER-2/neu oncoprotein.
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Radioiodinated antibody targeting of the HER-2/neu oncoprotein: effects of labeling method on cellular processing and tissue distribution.
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Radioiodinated ganglioside GM1: a potential tool for the investigation of ganglioside function in vivo.
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Radioiodinated metaiodobenzylguanidine in the diagnosis and therapy of carcinoid tumors.
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Radioiodination and astatination of octreotide by conjugation labeling.
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Radioiodination of a monoclonal antibody using N-succinimidyl 5-iodo-3-pyridinecarboxylate.
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Radioiodination of antibodies via N-succinimidyl 2,4-dimethoxy-3-(trialkylstannyl)benzoates.
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Radioiodination of internalizing monoclonal antibodies using N-succinimidyl 5-iodo-3-pyridinecarboxylate.
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Radioiodination of proteins using N-succinimidyl 4-hydroxy-3-iodobenzoate.
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Radioiodination via D-amino acid peptide enhances cellular retention and tumor xenograft targeting of an internalizing anti-epidermal growth factor receptor variant III monoclonal antibody.
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Radioiodine and 211At-labeled guanidinomethyl halobenzoyl octreotate conjugates: potential peptide radiotherapeutics for somatostatin receptor-positive cancers.
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Radiolabelling of glucose-Tyr3-octreotate with 125I and analysis of its metabolism in rats: comparison with radiolabelled DOTA-Tyr3-octreotate.
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Radiosynthesis and preliminary evaluation of 5-[123/125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine: a radioligand for nicotinic acetylcholine receptors.
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Rapid measurements of diastolic intramyocardial vascular volume.
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Re: Dosimetric consequences of increased seed strength for I-125 prostate implants. Radiother Oncol. 2003 Sep;68(3):295-7.
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Reagents for astatination of biomolecules: comparison of the in vivo distribution and stability of some radioiodinated/astatinated benzamidyl and nido-carboranyl compounds.
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Receptor binding sites for atrial natriuretic factor are expressed by brown adipose tissue.
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Receptors for sensory neuropeptides in human inflammatory diseases: implications for the effector role of sensory neurons.
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Recombinant human thyrotropin for the diagnosis and treatment of a highly functional metastatic struma ovarii.
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Regarding "A moment with endocrinology and metabolism" Maryland Medical Journal November 1993.
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Regional cerebral blood flow response to oral amphetamine challenge in healthy volunteers.
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Regional pulmonary distribution of iodine-125-labeled oleic acid. Its relationship to the pattern of oleic acid edema and pulmonary blood flow.
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Regulation of factor IXa in vitro in human and mouse plasma and in vivo in the mouse. Role of the endothelium and the plasma proteinase inhibitors.
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Response to the Letter by Katiman E., et al.
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Results of a phase II trial of transrectal ultrasound-guided permanent radioactive implantation of the prostate for definitive management of localized adenocarcinoma of the prostate (radiation therapy oncology group 98-05).
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Role of Thyroid RFA in the Treatment of Autonomously Functioning Thyroid Nodules.
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SIB-DOTA: a trifunctional prosthetic group potentially amenable for multi-modal labeling that enhances tumor uptake of internalizing monoclonal antibodies.
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SPECT/CT localization of oral radioiodine activity: a retrospective study and in-vitro assessment.
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Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results.
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Semiquantitative mIBG scoring as a prognostic indicator in patients with stage 4 neuroblastoma: a report from the Children's oncology group.
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Site-specific radioiodination of an anti-HER2 single domain antibody fragment with a residualizing prosthetic agent.
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Sodium-iodide symporter (NIS)-mediated accumulation of [(211)At]astatide in NIS-transfected human cancer cells.
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Solutions to problems in dose calibrator assay of iodine-123.
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Specific and high-level targeting of radiolabeled octreotide analogues to human medulloblastoma xenografts.
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Specific imaging of human brain tumor xenografts utilizing radiolabelled monoclonal antibodies (MAbs).
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Specificity, cross-reactivity, and affinity of 125I-labeled antiglioma antibodies for monolayers of cultured glioma cells.
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Stability of the beta-adrenergic receptor/adenylyl cyclase pathway of pediatric myocardium after brain death.
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Studying regional brain function: a challenge for SPECT.
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Substance P and substance K receptor binding sites in the human gastrointestinal tract: localization by autoradiography.
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Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein.
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Sulfhydryl-reactive, cleavable, and radioiodinatable benzophenone photoprobes for study of protein-protein interaction.
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Surgical management of strabismus following choroidal melanoma plaque brachytherapy.
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Synergistic interaction between anti-p185HER-2 ricin A chain immunotoxins and radionuclide conjugates for inhibiting growth of ovarian and breast cancer cells that overexpress HER-2.
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Synthesis and biological evaluation of an 123I-labeled bicyclic nucleoside analogue (BCNA) as potential SPECT tracer for VZV-tk reporter gene imaging.
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Synthesis and evaluation of glycosylated octreotate analogues labeled with radioiodine and 211At via a tin precursor.
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Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors.
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Synthesis and preliminary biological evaluation of (3-iodobenzoyl)norbiotinamide and ((5-iodo-3-pyridinyl)carbonyl)norbiotinamide: two radioiodinated biotin conjugates with improved stability.
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Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression.
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Synthesis of carrier-free 131I-meta-iodobenzyl-guanidine by novel routes to enhance therapeutic efficiency in neuroblastoma.
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Synthesis of iodine-125 labeled (+/-)-15-(4-azidobenzyl)carazolol: a potent beta-adrenergic photoaffinity probe.
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Synthesis of radioiodinated N-succinimidyl iodobenzoate: optimization for use in antibody labelling.
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Synthesis, purification, and in vitro stability of 211At- and 125I-labeled amidobisphosphonates.
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Targeting aldehyde dehydrogenase: a potential approach for cell labeling.
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Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody.
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Testing of local gamma-ray scatter fractions determined by spectral fitting.
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The 1999 patterns of care study of radiotherapy in localized prostate carcinoma: a comprehensive survey of prostate brachytherapy in the United States.
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The Impact of Pathologically Positive Lymph Nodes in the Clinically Negative Neck: An Analysis of 39,301 Patients with Papillary Thyroid Cancer.
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The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins.
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The cardiac beta-adrenergic receptor. Structural similarities of beta 1 and beta 2 receptor subtypes demonstrated by photoaffinity labeling.
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The clearance of a monoclonal anti-DNA antibody following administration of DNA in normal and autoimmune mice.
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The clearance of glycoproteins in diabetic mice.
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The distribution of intimal white blood cells in the normal rabbit aorta.
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The effects of local hyperthermia on the catabolism of a radioiodinated chimeric monoclonal antibody.
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The in vivo metabolism of antithrombin III and antithrombin III complexes.
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The rat testicular A1 adenosine receptor-adenylate cyclase system.
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The role of fine needle aspiration in the management of the thyroid nodule.
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Therapeutic efficacy of antiglioma mesenchymal extracellular matrix 131I-radiolabeled murine monoclonal antibody in a human glioma xenograft model.
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Thyroid Carcinoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
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Tissue distribution and radiation dosimetry of astatine-211-labeled chimeric 81C6, an alpha-particle-emitting immunoconjugate.
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Toxicity to neuroblastoma cells and spheroids of benzylguanidine conjugated to radionuclides with short-range emissions.
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Transfer of radioiodine from iodinated oncornavirus proteins to unlabeled protein carrier during routine procedures for peptide mapping.
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Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6.
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Truncated forms of the insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor encompassing the IGF-II binding site: characterization of a point mutation that abolishes IGF-II binding.
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Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts.
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Uptake mechanisms of meta-[123I]iodobenzylguanidine in isolated rat heart.
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Use of radiolabeled monoclonal anti-B1 antibody for B lymphocyte imaging in rhesus monkeys.
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Use of the 125I-labeled protein gel overlay technique to study calmodulin-binding proteins.
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Uveal melanoma treated with iodine-125 episcleral plaque: an analysis of dose on disease control and visual outcomes.
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Validation of 19F-magnetic resonance determination of myocardial blood volume.
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Validation of 4-[fluorine-18]fluoro-3-iodobenzylguanidine as a positron-emitting analog of MIBG.
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Variables associated with postoperative deep venous thrombosis: a prospective study of 411 gynecology patients and creation of a prognostic model.
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Vascular plasminogen activator levels and thromboembolic disease in patients with gynecologic malignancies.
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Vasoactive intestinal peptide (VIP) receptors in the canine gastrointestinal tract.
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Volume and activity quantitation with iodine-123 SPECT.
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Whole-body Tc-99m sestamibi scintigraphy in the follow-up of differentiated thyroid carcinoma.
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Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects.
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d-Amino Acid Peptide Residualizing Agents for Protein Radioiodination: Effect of Aspartate for Glutamate Substitution.
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Keywords of People
-
Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
-
Buckley, Anne Frances,
Assistant Professor of Pathology,
Pathology
-
Freemark, Michael Scott,
Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine,
Pediatrics, Endocrinology
-
McLendon, Roger Edwin,
Professor of Pathology,
Pathology
-
Pitt, Geoffrey Stuart,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
-
Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
-
Schwartz-Bloom, Rochelle D.,
Professor Emeritus of Pharmacology & Cancer Biology,
Duke Science & Society
-
Turkington, Timothy Garvey,
Associate Professor in Radiology,
Radiology