Isotopes
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Subject Areas on Research
- A rabbit irradiation platform for outcome assessment of lung stereotactic radiosurgery.
- A short-breath-hold technique for lung pO2 mapping with 3He MRI.
- A small animal model of regional alveolar ventilation using HP 3He MRI1.
- An evaluation of pulmonary atelectasis and its re-expansion: hyperpolarized 3He MRI in the Yorkshire pig.
- BiPS, a photocleavable, isotopically coded, fluorescent cross-linker for structural proteomics.
- Boron and strontium isotopic characterization of coal combustion residuals: validation of new environmental tracers.
- Cardiovascular Metabolomics.
- Current trends in differential expression proteomics: isotopically coded tags.
- Cystic fibrosis: combined hyperpolarized 3He-enhanced and conventional proton MR imaging in the lung--preliminary observations.
- Determination of regional VA/Q by hyperpolarized 3He MRI.
- Direct measurement of lung motion using hyperpolarized helium-3 MR tagging.
- Dynamic MRI of grid-tagged hyperpolarized helium-3 for the assessment of lung motion during breathing.
- Dynamic lung morphology of methacholine-induced heterogeneous bronchoconstriction.
- Dynamics of magnetization in hyperpolarized gas MRI of the lung.
- Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide.
- Evaluation of emphysema severity and progression in a rabbit model: comparison of hyperpolarized 3He and 129Xe diffusion MRI with lung morphometry.
- Functional MR microscopy of the lung using hyperpolarized 3He.
- Geochemical evidence for possible natural migration of Marcellus Formation brine to shallow aquifers in Pennsylvania.
- High Naturally Occurring Radioactivity in Fossil Groundwater in the Middle East
- Human lung air spaces: potential for MR imaging with hyperpolarized He-3.
- Hyperpolarized 3He MRI in Asthma
- Hyperpolarized 3He NMR lineshape measurements in the live guinea pig lung.
- Hyperpolarized 3He-enhanced MR imaging of lung transplant recipients: preliminary results.
- Hyperpolarized Gas MR Imaging: Technique and Applications.
- Hyperpolarized helium-3 MR imaging of pulmonary function.
- Imaging techniques for small animal models of pulmonary disease: MR microscopy.
- Impacts of shale gas wastewater disposal on water quality in western Pennsylvania.
- Isotope and ion selectivity in reverse osmosis desalination: geochemical tracers for man-made freshwater.
- MR grid-tagging using hyperpolarized helium-3 for regional quantitative assessment of pulmonary biomechanics and ventilation.
- MR microscopy of lung airways with hyperpolarized 3He.
- MR-compatible ventilator for small animals: computer-controlled ventilation for proton and noble gas imaging.
- Measurement of human CYP1A2 induction by inhalation exposure to benzo(a)pyrene based on in vivo isotope breath method.
- Measurement of regional lung function in rats using hyperpolarized 3helium dynamic MRI.
- Measurements of Regional Alveolar Oxygen Pressure Using Hyperpolarized 3He MRI1
- Measurements of hyperpolarized gas properties in the lung. Part III: (3)He T(1).
- Mixing oxygen with hyperpolarized (3)He for small-animal lung studies.
- Molecular MRI for sensitive and specific detection of lung metastases.
- Novel statistical methods for integrating genetic and stable isotope data to infer individual-level migratory connectivity.
- Pulmonary kinematics from tagged hyperpolarized helium-3 MRI.
- Quantification of Glycosaminoglycans in Urine by Isotope-Dilution Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry.
- Quantitative analysis of hyperpolarized 3He ventilation changes in mice challenged with methacholine.
- Quantitative assessment of emphysema using hyperpolarized 3He magnetic resonance imaging.
- Radioimmunotherapy with alpha-particle emitting radionuclides.
- Registered (1)H and (3)He magnetic resonance microscopy of the lung.
- Revisiting the Warburg Effect: Some Tumors Hold Their Breath.
- Semiautomated Ventilation Defect Quantification in Exercise-induced Bronchoconstriction Using Hyperpolarized Helium-3 Magnetic Resonance Imaging: A Repeatability Study.
- Single-acquisition sequence for the measurement of oxygen partial pressure by hyperpolarized gas MRI.
- Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part I: diffusion coefficient.
- Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part II: T *(2).
- Stable-isotope dilution GC-MS for determination of toluene in submilliliter volumes of whole blood.
- The isotopic composition of anthropogenic boron and its potential impact on the environment.
- The strontium isotope fingerprint of phosphate rocks mining.
- Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1.
- Using isotopic tools to dissect and quantitate parallel metabolic pathways.
- Ventilation defect percent in helium-3 magnetic resonance imaging as a biomarker of severe outcomes in asthma.
- Ventilation defects on hyperpolarized helium-3 MRI in asthma are predictive of 2-year exacerbation frequency.
- Ventilation/perfusion imaging in a rat model of airway obstruction.
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Keywords of People
- Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
- Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
- Hsu-Kim, Heileen, Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering
- Vengosh, Avner, Nicholas Distinguished Professor of Environmental Quality, Nicholas Institute-Energy Initiative