Japan

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  Subject Areas on Research

  • A Cluster Analysis of the Japanese Multicenter Outpatient Registry of Patients With Atrial Fibrillation. 
  • A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. 
  • A comparative study of monoclonal gammopathies and immunoglobulin levels in Japanese and United States elderly. 
  • A cost-effectiveness comparisons of adult spinal deformity surgery in the United States and Japan. 
  • A genome scan for hypertension susceptibility loci in populations of Chinese and Japanese origins. 
  • A nationwide survey of intravenous antimicrobial use in intensive care units in Japan. 
  • AOA-JOA Traveling Fellowship 2006: The Fellows' Travel Log. 
  • Adalimumab in Active and Inactive, Non-Infectious Uveitis: Global Results from the VISUAL I and VISUAL II Trials. 
  • Age and activity status affect muscle reoxygenation time after maximal cycling exercise. 
  • Ageing, status politics and sociological theory. 
  • An analysis of the reasons for Japan's low infant mortality rate. 
  • An international comparison of patients undergoing percutaneous coronary intervention: A collaborative study of the National Cardiovascular Data Registry (NCDR) and Japan Cardiovascular Database-Keio interhospital Cardiovascular Studies (JCD-KiCS). 
  • Angiotensin-converting enzyme gene and retinal arteriolar narrowing: the Funagata Study. 
  • Angle-closure glaucoma in Asians: comparison of biometric and anterior segment parameters between Japanese and Chinese subjects. 
  • Anhedonia in Japanese patients with Parkinson's disease: analysis using the Snaith-Hamilton Pleasure Scale. 
  • Apolipoprotein E in Creutzfeldt-Jakob disease. 
  • Assessment of the reductions in night-time blood pressure and dipping induced by antihypertensive medication using a home blood pressure monitor. 
  • Association between asleep blood pressure and brain natriuretic peptide during antihypertensive treatment: the Japan Morning Surge-Target Organ Protection (J-TOP) study. 
  • Association of Cardiovascular Outcomes With Masked Hypertension Defined by Home Blood Pressure Monitoring in a Japanese General Practice Population. 
  • Association of electrocardiographic left ventricular hypertrophy with incident cardiovascular disease in Japanese older hypertensive patients. 
  • Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations. 
  • Association of high pulse pressure with proteinuria in subjects with diabetes, prediabetes, or normal glucose tolerance in a large Japanese general population sample. 
  • Association of high-sensitivity cardiac troponin T and N-terminal pro-brain-type natriuretic peptide with left ventricular structure: J-HOP study. 
  • Association of the human type C retrovirus with a subset of adult T-cell cancers. 
  • Blunted cyclic variation of heart rate predicts mortality risk in post-myocardial infarction, end-stage renal disease, and chronic heart failure patients. 
  • Body dimensions of Japanese and American gymnasts. 
  • Body mass index and vein occlusion. 
  • Bootstrapping word order in prelexical infants: a Japanese-Italian cross-linguistic study. 
  • Both chronic kidney disease and nocturnal blood pressure associate with strokes in the elderly. 
  • Brief assessment of cognition in schizophrenia: validation of the Japanese version. 
  • CMPK1 and RBP3 are associated with corneal curvature in Asian populations. 
  • Changes in plasma unit distributions to hospitals over a 10-year period. 
  • Circulating des-acyl ghrelin improves cardiovascular risk prediction in older hypertensive patients. 
  • Clinical Impact of Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve on Japanese Population in the ADVANCE Registry. 
  • Clinical Impact of External Laryngeal Manipulation During Laryngoscopy on Tracheal Intubation Success in Critically Ill Children. 
  • Clinical Quantification of Myocardial Blood Flow Using PET: Joint Position Paper of the SNMMI Cardiovascular Council and the ASNC. 
  • Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan. 
  • Clinical trials in Japan and the United States. 
  • Clustering and heritability of insulin resistance in Chinese and Japanese hypertensive families: a Stanford-Asian Pacific Program in Hypertension and Insulin Resistance sibling study. 
  • Cognitions and behavior in asymmetric social dilemmas: a comparison of two cultures. 
  • Cohort profile: patient characteristics and quality-of-life measurements for newly-referred patients with atrial fibrillation-Keio interhospital Cardiovascular Studies-atrial fibrillation (KiCS-AF). 
  • Comment on "Can Minimally Invasive Esophagectomy Replace Open Esophagectomy for Esophageal Cancer? Latest Analysis of 24,233 Esophagectomies From the Japanese National Clinical Database". 
  • Comparative epitope mapping of sera from United States (US) and Japanese patients with bullous pemphigoid (BP) to fusion proteins encoded by BPAG1. 
  • Comparing the effects of ipragliflozin versus metformin on visceral fat reduction and metabolic dysfunction in Japanese patients with type 2 diabetes treated with sitagliptin: A prospective, multicentre, open-label, blinded-endpoint, randomized controlled study (PRIME-V study). 
  • Comparison of exudative age-related macular degeneration subtypes in Japanese and French Patients: multicenter diagnosis with multimodal imaging. 
  • Comparison of the efficacy, toxicity, and pharmacokinetics of a uracil/tegafur (UFT) plus oral leucovorin (LV) regimen between Japanese and American patients with advanced colorectal cancer: joint United States and Japan study of UFT/LV. 
  • Concepts of human differences: a comparison of American, Japanese, and Chinese children and adolescents. 
  • Cost-effectiveness of the oral adsorbent AST-120 versus placebo for chronic kidney disease. 
  • Cricoid Pressure During Induction for Tracheal Intubation in Critically Ill Children: A Report From National Emergency Airway Registry for Children. 
  • Cross-cultural variability of component processes in autobiographical remembering: Japan, Turkey, and the USA. 
  • Cross-linguistic studies of directionality in first language acquisition: the Japanese data--a response to O'Grady, Suzuki-Wei & Cho 1986. 
  • Cross-national comparison of sex differences in health and mortality in Denmark, Japan and the US. 
  • Day-by-Day Variability of Home Blood Pressure and Incident Cardiovascular Disease in Clinical Practice: The J-HOP Study (Japan Morning Surge-Home Blood Pressure). 
  • Decomposing change in life expectancy: a bouquet of formulas in honor of Nathan Keyfitz's 90th birthday. 
  • Dentatorubral-pallidoluysian atrophy and Haw River syndrome. 
  • Differences in care-seeking behavior for acute chest pain in the United States and Japan. 
  • Discrimination of phonemic vowel length by Japanese infants. 
  • Effect of dosing time of angiotensin II receptor blockade titrated by self-measured blood pressure recordings on cardiorenal protection in hypertensives: the Japan Morning Surge-Target Organ Protection (J-TOP) study. 
  • Effectiveness of high rate and delayed detection ICD programming by race: A MADIT-RIT substudy. 
  • Effects and limitations of prosodic and semantic biases on syntactic disambiguation. 
  • Effects of low-dose atrial natriuretic peptide infusion on cardiac surgery-associated acute kidney injury: A multicenter randomized controlled trial. 
  • Efficacy and safety of recombinant factor XIII on reducing blood transfusions in cardiac surgery: a randomized, placebo-controlled, multicenter clinical trial. 
  • Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial. 
  • Efficacy of eplerenone added to renin-angiotensin blockade in elderly hypertensive patients: the Jichi-Eplerenone Treatment (JET) study. 
  • Emergence of Japanese infants' prosodic preferences in infant-directed vocabulary. 
  • Epstein-Barr Virus Antibody Titers Are Not Associated with Gastric Cancer Risk in East Asia. 
  • Ethnic Variations in Radiographic Parameters and SRS-22 Scores in Adult Spinal Deformity: A Comparison Between North American and Japanese Patients Above 50 Years of Age With Minimum 2-Year Follow-up. 
  • Even at 4 months, a labial is a good enough coronal, but not vice versa. 
  • Evening heart rate measured at home is associated with visceral obesity and abnormal fat distribution in patients with hypertension. 
  • Evolution and diversity in human herpes simplex virus genomes. 
  • Exposure to Atomic Bomb Radiation and Age-Related Macular Degeneration in Later Life: The Hiroshima-Nagasaki Atomic Bomb Survivor Study. 
  • External Validation for Acute Kidney Injury Severity Scores: A Multicenter Retrospective Study in 14 Japanese ICUs. 
  • Factors affecting prolonged length of stay in psychiatric patients in Japan: A retrospective observational study. 
  • Female aggression and male membership in troops of Japanese macaques and olive baboons. 
  • Fruit and vegetable consumption, Helicobacter pylori antibodies, and gastric cancer risk: A pooled analysis of prospective studies in China, Japan, and Korea. 
  • Further scrutiny of scientific whaling. 
  • Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. 
  • Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. 
  • Genomewide search for type 2 diabetes susceptibility genes in four American populations. 
  • Global cardiovascular device innovation: Japan-USA synergies: Harmonization by Doing (HBD) program, a consortium of regulatory agencies, medical device industry, and academic institutions. 
  • Glycohemoglobin not as predictive as fasting glucose as a measure of prediabetes in predicting proteinuria. 
  • Hemoglobin Rahere, a human hemoglobin variant with amino acid substitution at the 2,3-diphosphoglycerate binding site. Functional consequences of the alteration and effects of bezafibrate on the oxygen bindings. 
  • Hospital mortality of patients aged 80 and older after surgical repair for type A acute aortic dissection in Japan. 
  • Impact of postoperative pneumonia following pituitary surgery. 
  • Impact of sheath size and hemostasis time on radial artery patency after transradial coronary angiography and intervention in Japanese and non-Japanese patients: A substudy from RAP and BEAT (Radial Artery Patency and Bleeding, Efficacy, Adverse evenT) randomized multicenter trial. 
  • Impaired glucose tolerance, but not impaired fasting glucose, is associated with retinopathy in Japanese population: the Funagata study. 
  • Industry perspectives on ICH guidelines. 
  • Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. 
  • It takes two to mimic: behavioral consequences of self-construals. 
  • Japan-United States of America Harmonized Assessment by Randomized Multicentre Study of OrbusNEich's Combo StEnt (Japan-USA HARMONEE) study: primary results of the pivotal registration study of combined endothelial progenitor cell capture and drug-eluting stent in patients with ischaemic coronary disease and non-ST-elevation acute coronary syndrome. 
  • Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease. 
  • Language-general biases and language-specific experience contribute to phonological detail in toddlers' word representations. 
  • Late Effects of Exposure to Ionizing Radiation and Age on Human Thymus Morphology and Function. 
  • Links between family relationships and best friendships in the United States and Japan. 
  • Long-Term Blood Pressure Variability, New-Onset Diabetes Mellitus, and New-Onset Chronic Kidney Disease in the Japanese General Population. 
  • Long-Term Survival in Patients With Acute Kidney Injury After Acute Type A Aortic Dissection Repair. 
  • Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. 
  • Lower Satisfaction After Adult Spinal Deformity Surgery in Japan Than in the United States Despite Similar SRS-22 Pain and Function Scores: A Propensity-Score Matched Analysis. 
  • MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration. 
  • Microsurgery: past, present, and future. 
  • Modeling daily flowering probabilities: expected impact of climate change on Japanese cherry phenology. 
  • Morning and Evening Home Blood Pressure and Risks of Incident Stroke and Coronary Artery Disease in the Japanese General Practice Population: The Japan Morning Surge-Home Blood Pressure Study. 
  • Morning blood pressure surge, morning platelet aggregation, and silent cerebral infarction in older Japanese hypertensive patients. 
  • Mortality patterns in developed countries. 
  • Mortality reduction in relation to implantable cardioverter defibrillator programming in the Multicenter Automatic Defibrillator Implantation Trial-Reduce Inappropriate Therapy (MADIT-RIT). 
  • Mothers speak less clearly to infants than to adults: a comprehensive test of the hyperarticulation hypothesis. 
  • Multicenter automatic defibrillator implantation trial: reduce inappropriate therapy (MADIT-RIT): background, rationale, and clinical protocol. 
  • Muscle contraction-induced limb blood flow variability during dynamic knee extensor. 
  • Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial. 
  • New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey. 
  • New-onset hypertension and risk for chronic kidney disease in the Japanese general population. 
  • Nighttime Blood Pressure Measured by Home Blood Pressure Monitoring as an Independent Predictor of Cardiovascular Events in General Practice. 
  • Novel ICD Programming and Inappropriate ICD Therapy in CRT-D Versus ICD Patients: A MADIT-RIT Sub-Study. 
  • On-Treatment Blood Pressure and Cardiovascular Outcomes in Older Adults With Isolated Systolic Hypertension. 
  • Outcomes in two Japanese adenosine deaminase-deficiency patients treated by stem cell gene therapy with no cytoreductive conditioning. 
  • Pathology and imaging of hepatocellular neoplasms: are findings from Asian populations applicable to non-Asian groups? 
  • Pharmaceutical prices, quantities and innovation. Comparing Japan with the US. 
  • Phonological theory informs the analysis of intonational exaggeration in Japanese infant-directed speech. 
  • Phylogeny and biogeography of East Asian evergreen oaks (Quercus section Cyclobalanopsis; Fagaceae): Insights into the Cenozoic history of evergreen broad-leaved forests in subtropical Asia. 
  • Physician attire in the intensive care unit in Japan influences visitors' perception of care. 
  • Planning and response to radiation exposures. 
  • Post-exercise hyperemia after ischemic and non-ischemic isometric handgrip exercise. 
  • Potentially functional variants in the core nucleotide excision repair genes predict survival in Japanese gastric cancer patients. 
  • Predictive processing of novel compounds: evidence from Japanese. 
  • Predictors of Hospital Readmission and Surgical Site Infection in the United States, Denmark, and Japan: Is Risk Stratification a Universal Language? 
  • Prevalence and associations of epiretinal membranes in an adult Japanese population: the Funagata study. 
  • Prevalence and risk factors for age-related macular degeneration in an adult Japanese population: the Funagata study. 
  • Processing down the garden path in Japanese: processing of sentences with lexical homonyms. 
  • Prognostic value of estimated plasma volume in acute heart failure in three cohort studies. 
  • Prosodic planning while reading aloud: on-line examination of Japanese sentences. 
  • Racial impact of diurnal variations in blood pressure on cardiovascular events in chronic kidney disease. 
  • Radiation- and Age-Associated Changes in Peripheral Blood Dendritic Cell Populations among Aging Atomic Bomb Survivors in Japan. 
  • Re: Evidence for an "epidemic" of myopia. 
  • Recent changes in the U.S. age at death distribution: further observations. 
  • Reduction in Inappropriate ICD Therapy in MADIT-RIT Patients Without History of Atrial Tachyarrhythmia. 
  • Regional differences in gallbladder cancer pathogenesis: Insights from a multi-institutional comparison of tumor mutations. 
  • Regional differences in hypertensive cardiovascular remodeling between fishing and farming communities in Japan. 
  • Replicating and extending the effects of auditory religious cues on dishonest behavior. 
  • Response to 'Supra-linear dose-response in the A-bomb study'. 
  • Retinal arteriolar narrowing predicts 5-year risk of hypertension in Japanese people: the Funagata study. 
  • Risk Profile and 1-Year Outcome of Newly Diagnosed Atrial Fibrillation in Japan　- Insights From GARFIELD-AF. 
  • Risk factors and mortality in invasive Rasamsonia spp. infection: Analysis of cases in the FungiScope® registry and from the literature. 
  • Risk factors for early unplanned readmission in patients with bipolar disorder: A retrospective observational study. 
  • SMBE proposal to the government of Japan. 
  • Segmental distributions and consonant-vowel association patterns in Japanese infant- and adult-directed speech. 
  • Seroprevalence of HTLV-I in Cheju Island, a Korean island adjacent to the endemic area of Japan. 
  • Should reperfusion strategies in myocardial infarction be modified for the very elderly? 
  • Smoking, Helicobacter Pylori Serology, and Gastric Cancer Risk in Prospective Studies from China, Japan, and Korea. 
  • Social motivation affecting individuals' actions in Japan during World War II: historical review. 
  • Speculation on the naming of Moyamoya disease. 
  • Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. 
  • Study protocol for a randomised controlled trial of cognitive processing therapy for post-traumatic stress disorder among Japanese patients: the Safety, Power, Intimacy, Esteem, Trust (SPINET) study. 
  • Survival after the age of 80 in the United States, Sweden, France, England, and Japan. 
  • Synergistic effect of chronic kidney disease and high circulatory norepinephrine level on stroke risk in Japanese hypertensive patients. 
  • Taming the wilderness: the lifestyle improvement movement in rural Japan, 1925-1965. 
  • Temporal changes in FFRCT-Guided Management of Coronary Artery Disease - Lessons from the ADVANCE Registry. 
  • The U-shaped association between body mass index and gastric cancer risk in the Helicobacter pylori Biomarker Cohort Consortium: A nested case-control study from eight East Asian cohort studies. 
  • The clinical evaluation of the Endeavor zotarolimus-eluting coronary stent in Japanese patients with de novo native coronary artery lesions: primary results and 3-year follow-up of the Endeavor Japan study. 
  • The development of a phonological illusion: a cross-linguistic study with Japanese and French infants. 
  • The development of perceptual grouping biases in infancy: a Japanese-English cross-linguistic study. 
  • The impact of cigarette smoking on 24-hour blood pressure, inflammatory and hemostatic activity, and cardiovascular risk in Japanese hypertensive patients. 
  • The impact of the international guideline entitled Statistical Principles for Clinical Trials (ICH E9). 
  • The metabolic syndrome and retinal microvascular signs in a Japanese population: the Funagata study. 
  • The multidimensional nature of hyperspeech: evidence from Japanese vowel devoicing. 
  • The next generation: the need to expand upon traditional risk factors for stroke. 
  • The remarkable improvements in survival at older ages. 
  • Ticlopidine-associated ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in 22 persons in Japan: a report from the Southern Network on Adverse Reactions (SONAR). 
  • Tolerability and efficacy of durvalumab in Japanese patients with advanced solid tumors. 
  • Urinary Angiotensinogen Could Be a Prognostic Marker of Renoprotective Effects of Alogliptin in Patients with Type 2 Diabetes. 
  • Utility of the Penn classification in predicting outcomes of surgery for acute type a aortic dissection. 
  • Validity of low-intensity continuous renal replacement therapy*. 
  • Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma. 
  • Volume effect in paediatric brain tumour resection surgery: analysis of data from the Japanese national inpatient database. 
  • Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations. 
  • Widowhood and illness: a comparison of social network characteristics in France, Germany, Japan, and the United States. 
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  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology