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Subject Areas on Research
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A panel of antibodies useful in the cytologic diagnosis of metastatic melanoma.
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A radiologic sign of epidermolytic hyperkeratosis.
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A structural comparison of tryptic fragments of three types of intermediate filaments.
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An immunohistochemical comparison of cytokeratin 7, cytokeratin 15, cytokeratin 19, CAM 5.2, carcinoembryonic antigen, and nestin in differentiating porocarcinoma from squamous cell carcinoma.
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Analysis of corneal and conjunctival microenvironments using monoclonal antibodies.
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Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001.
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Analysis of neurogenesis in a mammalian neuroepithelium: proliferation and differentiation of an olfactory neuron precursor in vitro.
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Aneuploid subpopulations in tumour-invaded lymph nodes from breast cancer patients.
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Antibody against T lymphoblastic leukemia-associated antigen (3-40) identifies vimentin and keratin intermediate filaments in normal cells.
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Are metaplasias in colorectal adenomas truly metaplasias?
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Arsenic exposure of rural populations from the Rift Valley of Ethiopia as monitored by keratin in toenails.
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Asymmetric cell divisions promote stratification and differentiation of mammalian skin.
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Basal cell-signet-ring squamous cell carcinoma of the eyelid.
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Basal-like cells constitute the proliferating cell population in cystic fibrosis airways.
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Cadmium-induced neoplastic transformation of human prostate epithelial cells.
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Carcinoma of the Middle Ear: A Review of the National Cancer Database.
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Characterization of a monoclonal antibody, RTE-21, that binds to keratohyalin granule-associated proteins in epithelial cells of human skin and thymus.
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Characterization of cultured thymus tissue used for transplantation with emphasis on promiscuous expression of thyroid tissue-specific genes.
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Characterization of keratinocyte plasminogen activator inhibitors and demonstration of the prevention of pemphigus IgG-induced acantholysis by a purified plasminogen activator inhibitor.
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Characterization of potential precursor populations in the mouse olfactory epithelium using immunocytochemistry and autoradiography.
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Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model.
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Cloning and characterization of cytokeratins 8 and 19 in adult rat striated muscle. Interaction with the dystrophin glycoprotein complex.
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Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo.
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Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi.
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Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.
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Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus.
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Cytokeratin 12 in human ocular surface epithelia is the antigen reactive with a commercial anti-Galpha q antibody.
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Cytoplasmic staining of TTF-1 in the differential diagnosis of hepatocellular carcinoma vs cholangiocarcinoma and metastatic carcinoma of the liver.
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Desmoplakin I and desmoplakin II. Purification and characterization.
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Desmoplakin controls microvilli length but not cell adhesion or keratin organization in the intestinal epithelium.
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Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer.
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Differential effects of interleukin-1 alpha, tumor necrosis factor-alpha, indomethacin, hydrocortisone, and macrophage co-culture on the proliferation of human fibroblasts and peritoneal mesothelial cells.
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Differential localization of placental extracellular superoxide dismutase as pregnancy progresses.
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Ductal epithelial proliferations of the breast: a biological continuum? Comparative genomic hybridization and high-molecular-weight cytokeratin expression patterns.
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Dynamic evolution of the alpha (α) and beta (β) keratins has accompanied integument diversification and the adaptation of birds into novel lifestyles.
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Electron immunocytochemical analysis of posterior hyaloid associated with diabetic macular edema.
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Endothelial metaplasia in the iridocorneal endothelial syndrome.
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Epidermal keratinocytes express the adhesion molecule intercellular adhesion molecule-1 in inflammatory dermatoses.
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Evaluation of squamous epithelium in adenoacanthoma and adenosquamous carcinoma of the endometrium: immunoperoxidase analysis of involucrin and keratin localization.
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Expression of specific keratin markers by rabbit corneal, conjunctival, and esophageal epithelia during vitamin A deficiency.
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Expression of unusually large keratins during terminal differentiation: balance of type I and type II keratins is not disrupted.
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Extrusion of abnormal endothelium into the posterior corneal stroma in a patient with posterior polymorphous dystrophy.
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Feather development genes and associated regulatory innovation predate the origin of Dinosauria.
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Fine-needle aspiration of primary gallbladder carcinoma.
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Fine-needle-aspiration cytology of a proximal type epithelioid sarcoma: A case report.
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Goblet-cell mucinous epithelium lining the endometrium and endocervix: evidence of metastasis from an appendiceal primary tumor through the use of cytokeratin-7 and -20 immunostains.
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High yield reproducible rat model recapitulating human Barrett's carcinogenesis.
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Human colorectal carcinomas specifically accumulate Mr 42,000 ubiquitin-conjugated cytokeratin 8 fragments.
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Identification of a cell of origin for human prostate cancer.
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Immunohistochemical analysis of the pathogenesis of posterior polymorphous dystrophy.
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Immunohistochemical characterization of neuroendocrine cells in prostate cancer.
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Immunohistochemical differentiation of sarcomatoid mesotheliomas from other spindle cell neoplasms.
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Immunohistochemistry of the canine vomeronasal organ.
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Immunohistochemistry of the canine vomeronasal organ.
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Immunophenotype and molecular characterisation of adenocarcinoma of the small intestine.
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Increased production of sonic hedgehog by ballooned hepatocytes.
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Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle.
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Integration of peripheral blood biomarkers with computed tomography to differentiate benign from malignant pulmonary opacities.
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Invited commentary.
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Isolation and characterization of biliary epithelial cells from rainbow trout liver.
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Keratin Profiling by Single-Cell RNA-Sequencing Identifies Human Prostate Stem Cell Lineage Hierarchy and Cancer Stem-Like Cells.
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Long-term primary culture of epithelial cells from rainbow trout Oncorhynchus mykiss) liver.
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Lysosomes and the skin.
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Lysosomes and the skin.
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Malignant mesothelioma with heterologous elements: clinicopathological correlation of 27 cases and literature review.
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Migrating keratinocytes express urokinase-type plasminogen activator.
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Milium-like syringoma: a case study on histogenesis.
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Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines.
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Molecular mechanisms of development of the human fetal female reproductive tract.
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Monoclonal antibody 4F2 reactive with basal layer keratinocytes: studies in the normal and a hyperproliferative state.
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Mouse keratin 4 is necessary for internal epithelial integrity.
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Multiply recurrent trichilemmal carcinoma with perineural invasion and cytokeratin 17 positivity.
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Ontogeny of the human thymus during fetal development.
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Parent-specific expression of a human keratin 18/beta-galactosidase fusion gene in transgenic mice.
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Partial hepatectomy and bile duct ligation in rainbow trout (Oncorhynchus mykiss): histologic, immunohistochemical and enzyme histochemical characterization of hepatic regeneration and biliary hyperplasia.
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Phenotypic characterization and ontogeny of mesodermal-derived and endocrine epithelial components of the human thymic microenvironment.
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Polypoid tumor of the esophagus.
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Preneoplastic and neoplastic lesions of rat hereditary renal cell tumors express markers of proximal and distal nephron.
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Progesterone receptor activity in leiomyomatosis peritonealis disseminata.
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Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial.
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Proteomic analysis of desmosomes reveals novel components required for epidermal integrity.
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Pulmonary carcinomas with a sarcomatoid element: an immunocytochemical and ultrastructural analysis.
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Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study.
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Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor beta.
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Remarkable conservation of structure among intermediate filament genes.
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Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis.
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Roles for Ndel1 in keratin organization and desmosome function.
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SNAP29 mediates the assembly of histidine-induced CTP synthase filaments in proximity to the cytokeratin network.
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Sarcomatoid Peritoneal Mesothelioma: Clinicopathologic Correlation of 13 Cases.
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Serum CYFRA 21-1 in advanced stage non-small cell lung cancer: an early measure of response.
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Suppression of endo B cytokeratin by its antisense RNA inhibits the normal coexpression of endo A cytokeratin.
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The diagnostic distinction between malignant mesothelioma of the pleura and adenocarcinoma of the lung as defined by a monoclonal antibody (B72.3).
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The human keratin genes and their differential expression.
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The human thymic microenvironment during organ culture.
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The human thymic microenvironment. Phenotypic characterization of Hassall's bodies with the use of monoclonal antibodies.
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The human thymic microenvironment: thymic epithelium contains specific keratins associated with early and late stages of epidermal keratinocyte maturation.
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The human thymus. A chimeric organ comprised of central and peripheral lymphoid components.
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The nature and significance of differential keratin gene expression.
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The thymic microenvironment. Characterization of in vitro differentiation of the IT26R21 rat thymic epithelial cell line.
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The use of a panel of monoclonal antibodies in ultrastructurally characterized small cell carcinomas of the lung.
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Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes.
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Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer.
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Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin.
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Visualization of a 21-nm axial periodicity in shadowed keratin filaments and neurofilaments.
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Keywords of People
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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Moorman, Patricia Gripka,
Professor Emeritus in Family Medicine and Community Health,
Duke Cancer Institute