Ketoconazole

• 

  Subject Areas on Research

  • A phase I study of estramustine, weekly docetaxel, and carboplatin chemotherapy in patients with hormone-refractory prostate cancer. 
  • A prospective randomized trial of OKT3 vs ATGAM induction therapy in pancreas transplant recipients. 
  • Adrenal androgen levels as predictors of outcome in prostate cancer patients treated with ketoconazole plus antiandrogen withdrawal: results from a cancer and leukemia group B study. 
  • Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583). 
  • Binding and metabolism of 1,25-dihydroxyvitamin D3 in cultured bovine parathyroid cells. 
  • Blastomycosis. New treatment for an old friend of the Carolinas. 
  • Candida albicans corpora abscess following penile prosthesis placement. 
  • Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits. 
  • Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanil. 
  • Cutaneous infection caused by Curvularia pallescens: a case report and review of the spectrum of disease. 
  • Effect of ketoconazole on the pharmacokinetic profile of buprenorphine following administration of a once-weekly buprenorphine transdermal system. 
  • Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment. 
  • Efficacy of docetaxel-based chemotherapy following ketoconazole in metastatic castration-resistant prostate cancer: implications for prior therapy in clinical trials. 
  • Failure of ketoconazole in cryptococcal meningitis. 
  • Fungal scleritis after cataract surgery. Successful outcome using itraconazole. 
  • Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4. 
  • Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy. 
  • Increased risk of pulmonary edema in diabetic patients undergoing preemptive pancreas transplantation with OKT3 induction. 
  • Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers. 
  • Intervertebral diskitis due to Candida tropicalis. 
  • Ketoconazole retains activity in patients with docetaxel-refractory prostate cancer. 
  • Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes. 
  • Mitochondrial Genome Variation Affects Multiple Respiration and Nonrespiration Phenotypes in Saccharomyces cerevisiae. 
  • Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial. 
  • Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits. 
  • Penetration of new azole compounds into the eye and efficacy in experimental Candida endophthalmitis. 
  • Pharmacotherapy of disseminated histoplasmosis in patients with AIDS. 
  • Prediction of relapse after treatment of coccidioidomycosis. 
  • Susceptibilities of clinical and laboratory isolates of Blastomyces dermatitidis to ketoconazole, itraconazole, and fluconazole. 
  • The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90401) (Alliance). 
  • The pharmacokinetics of BAY R3783 and its efficacy in the treatment of experimental cryptococcal meningitis. 
  • Transient increase in plasma quinidine concentrations during ketoconazole-quinidine therapy. 
  • Treatment of experimental cryptococcal meningitis with amphotericin B, 5-fluorocytosine, and ketoconazole. 
  • Treatment of isolated laryngeal blastomycosis with ketoconazole. Photographic documentation of a successful case. 
  • Treatment of sporotrichosis with itraconazole. NIAID Mycoses Study Group. 
  • Tricuspid valve Candida endocarditis. Successful treatment with valve-sparing debridement and antifungal chemotherapy in a multiorgan transplant recipient. 
  • Uptake of itraconazole by alveolar macrophages. 
  • Use of fluconazole in a patient with documented malabsorption of ketoconazole. 
  • Use of ketoconazole to probe the pathogenetic importance of 1,25-dihydroxyvitamin D in absorptive hypercalciuria. 
  • Use of oral ketoconazole to prevent postoperative erections following penile surgery. 
  • [Effects of ketoconazole on the immune system. I. In vitro effects on lymphocyte functions]. 
• 

  Keywords of People

  • Halabi, Susan, Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery