Ketones

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  Subject Areas on Research

  • 2-Azadienes as Reagents for Preparing Chiral Amines: Synthesis of 1,2-Amino Tertiary Alcohols by Cu-Catalyzed Enantioselective Reductive Couplings with Ketones. 
  • A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia: a randomized, controlled trial. 
  • A spectrophotometric glutathione S-transferase assay displaying alpha-class selectivity utilizing 1-p-chlorophenyl-4,4-dimethyl-5-diethylamino-1-penten-3- one hydrobromide. 
  • Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen. 
  • Authors' reply to Letter to the Editor regarding: Impaction durability of porous PEEK and titanium-coated PEEK interbody fusion devices. 
  • Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis. 
  • Catalytic enantioselective alkylation of substituted dioxanone enol ethers: ready access to Calpha-tetrasubstituted hydroxyketones, acids, and esters. 
  • Chemico-Biological Interactions. Enzymology and molecular biology of carbonyl metabolism 16. Introduction. 
  • Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. 
  • Diet therapy for narcolepsy. 
  • Do Surface Porosity and Pore Size Influence Mechanical Properties and Cellular Response to PEEK? 
  • Effect of porous orthopaedic implant material and structure on load sharing with simulated bone ingrowth: A finite element analysis comparing titanium and PEEK. 
  • Effects of Surface Topography and Chemistry on Polyether-Ether-Ketone (PEEK) and Titanium Osseointegration. 
  • Electron paramagnetic resonance studies of iron reduction and semiquinone formation in metalloflavoproteins. 
  • Enantioselective Intermolecular Pd-Catalyzed Hydroalkylation of Acyclic 1,3-Dienes with Activated Pronucleophiles. 
  • Enantioselective decarboxylative alkylation reactions: catalyst development, substrate scope, and mechanistic studies. 
  • Failure of a polyether-ether-ketone expandable interbody cage following transforaminal lumbar interbody fusion. 
  • Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. 
  • Fivefold higher rate of pseudarthrosis with polyetheretherketone interbody device than with structural allograft used for 1-level anterior cervical discectomy and fusion. 
  • Genetic variants in PDSS1 and SLC16A6 of the ketone body metabolic pathway predict cutaneous melanoma-specific survival. 
  • Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. 
  • High-strength, surface-porous polyether-ether-ketone for load-bearing orthopedic implants. 
  • Impaction durability of porous polyether-ether-ketone (PEEK) and titanium-coated PEEK interbody fusion devices. 
  • Initial testing (stage 1) of eribulin, a novel tubulin binding agent, by the pediatric preclinical testing program. 
  • Isocoproporphyrin: nuclear-magnetic-resonance-and mass-spectral methods for the determination of porphyrin structure. 
  • Local deformation behavior of surface porous polyether-ether-ketone. 
  • Luminescent Difluoroboron β-Diketonate PLA-PEG Nanoparticle. 
  • Metabolic profiles predict adverse events after coronary artery bypass grafting. 
  • Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs. 
  • Ozone-initiated chemistry in an occupied simulated aircraft cabin. 
  • Phase II California Cancer Consortium Trial of Gemcitabine-Eribulin Combination in Cisplatin-Ineligible Patients With Metastatic Urothelial Carcinoma: Final Report (NCI-9653). 
  • Plasma glucose response to recreational diving in novice teenage divers with insulin-requiring diabetes mellitus. 
  • Porous PEEK improves the bone-implant interface compared to plasma-sprayed titanium coating on PEEK. 
  • Potentially functional genetic variants in PLIN2, SULT2A1 and UGT1A9 genes of the ketone pathway and survival of nonsmall cell lung cancer. 
  • Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults. 
  • Stereoselective synthesis of 2,6-trans-tetrahydropyran via primary diamine-catalyzed oxa-conjugate addition reaction of α,β-unsaturated ketone: total synthesis of psymberin. 
  • Structural requirements for high affinity ligand binding by estrogen receptors: a comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast, and mammalian cells. 
  • Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme. 
  • The Utility of Polyether-Ether-Ketone Implants Adjacent to Sinus Cavities After Craniofacial Trauma. 
  • The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot study. 
  • The effects of varying dietary carbohydrate and fat content on survival in a murine LNCaP prostate cancer xenograft model. 
  • Vapor detection and discrimination with a panel of odorant receptors. 
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  Keywords of People

  • Hirschey, Matthew, Associate Professor of Medicine, Pharmacology & Cancer Biology
  • Yancy Jr., William Samuel, Associate Professor of Medicine, Medicine, General Internal Medicine