Kidney Tubules

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  Subject Areas on Research

  • A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. 
  • Abnormal iron deposition in renal cells in the rat with chronic angiotensin II administration. 
  • Absence of tubuloglomerular feedback responses in AT1A receptor-deficient mice. 
  • Acute kidney injury to chronic kidney disease transition: insufficient cellular stress response. 
  • Altered expression of transforming growth factor-alpha: an early event in renal cell carcinoma development. 
  • Analysis and isolation of renal tubular cells by flow cytometry. 
  • Anesthetic effects on the glycerol model of rhabdomyolysis-induced acute renal failure in rats. 
  • Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption. 
  • Atypical tubule hyperplasia and renal tubule tumors in conventional rats on 90-day toxicity studies. 
  • C-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent. 
  • Calcium stone disease: an overview. 
  • Changes in Urinary Microbiome Populations Correlate in Kidney Transplants With Interstitial Fibrosis and Tubular Atrophy Documented in Early Surveillance Biopsies. 
  • Characteristics of lysine transport by isolated rat renal cortical tubule fragments. 
  • Characteristics of lysine uptake by isolated renal cortical tubule fragments from mature and immature dogs. 
  • Clinical pharmacology of benoxaprofen. 
  • Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or lupus-like disease. 
  • Computed tomographic diagnosis of the obstructed duplex kidney in adults. 
  • Correlations of serum concentrations of 1,25-dihydroxyvitamin D, phosphorus, and parathyroid hormone in tumoral calcinosis. 
  • Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells. 
  • Developmental changes of glycine transport in the dog. 
  • Developmental pattern of cystine transport in isolated rat renal tubules. 
  • Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs. 
  • Disorders of cell volume regulation. I. Effects of inhibition of plasma membrane adenosine triphosphatase with ouabain. 
  • Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. 
  • Early onset of spontaneous renal preneoplastic and neoplastic lesions in young conventional rats in toxicity studies. 
  • Effect of cystine loading and cystine dimethylester on renal brushborder membrane transport. 
  • Effect of cystine loading on substrate oxidation by rat renal tubules. 
  • Exfoliative cytopathologic studies in organ transplantation. 3. The cytologic profile of urine during acute renal allograft rejection. 
  • Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation. 
  • Gentamicin inhibits rat renal cortical homotypic endosomal fusion: role of megalin. 
  • Glycogen storage disease type Ia in two littermate Maltese puppies. 
  • Gq signaling causes glomerular injury by activating TRPC6. 
  • HIF-1α inducing exosomal microRNA-23a expression mediates the cross-talk between tubular epithelial cells and macrophages in tubulointerstitial inflammation. 
  • HIV infection-induced transcriptional program in renal tubular epithelial cells activates a CXCR2-driven CD4+ T-cell chemotactic response. 
  • HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells. 
  • HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells. 
  • HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. 
  • Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis. 
  • Heterogeneity in the distal nephron of the salamander (Ambystoma tigrinum): a correlated structure function study of isolated tubule segments. 
  • Homocystine uptake in isolated rat renal cortical tubules. 
  • Hypoxanthine uptake in isolated rat renal cortical tubule fragments. 
  • Immunological mechanisms of allograft rejection. 
  • Increased susceptibility to in vitro transformation of cells carrying the Eker tumor susceptibility mutation. 
  • Integrative Genomics Identifies Novel Associations with APOL1 Risk Genotypes in Black NEPTUNE Subjects. 
  • Intracellular potassium activity in rabbit sinoatrial node. Evaluation during spontaneous activity and arrest. 
  • In vitro generation of renal tubular epithelial cells from fibroblasts: implications for precision and regenerative medicine in nephrology. 
  • Kidney lesions in Rocky Mountain spotted fever: a light-, immunofluorescence-, and electron-microscopic study. 
  • Laser-capture microdissection. 
  • Lithium-induced renal ectasia. 
  • Longitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null mice. 
  • Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation. 
  • Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis. 
  • Morphology of rabbit collecting duct. 
  • Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression. 
  • Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis. 
  • Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits. 
  • Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome. 
  • Polarity of alpha-galactosidase A uptake by renal tubule cells. 
  • Polyploidy and Mitotic Cell Death Are Two Distinct HIV-1 Vpr-Driven Outcomes in Renal Tubule Epithelial Cells. 
  • Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages. 
  • Pseudohypoparathyroidism type II: a possible defect in the reception of the cyclic AMP signal. 
  • Pseudotumors due to IgG4 immune-complex tubulointerstitial nephritis associated with autoimmune pancreatocentric disease. 
  • Randomized trial of the anti-FGF23 antibody KRN23 in X-linked hypophosphatemia. 
  • Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II. 
  • Renal allografts in HL-A matched recipients. Light, immunofluorescence and electron microscopic studies. 
  • Renal epithelial dysplasia. 
  • Renal tubular cell expression of MHC class II (I-Eb) is insufficient to initiate immune injury in a transgenic kidney transplant model. 
  • Renal uptake of lutropin. Studies based on electron microscopic autoradiography and nephrectomy. 
  • Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons. 
  • Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA. 
  • Studies on cellular autophagocytosis. The relationship of autophagocytosis to protein synthesis and to energy metabolism in rat liver and flounder kidney tubules in vitro. 
  • Susceptibility tensor imaging of the kidney and its microstructural underpinnings. 
  • Suspension of medullary thick ascending limb tubules from the rabbit kidney. 
  • Synthetic atrial natriuretic factor decreases renal tubular phosphate reabsorption in rats. 
  • Targeting Glomerular Hemodynamics for Kidney Protection. 
  • Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease. 
  • The Fanconi syndrome and mechanisms of tubular transport dysfunction. 
  • The administration of renoprotective agents extends warm ischemia in a rat model. 
  • The aquaporins, blueprints for cellular plumbing systems. 
  • The concurrence of hypoparathyroidism provides new insights to the pathophysiology of X-linked hypophosphatemic rickets. 
  • The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats. 
  • The effect of phosphate infusions upon renal phosphate clearance in man: evidence for tubular phosphate secretion. 
  • The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation. 
  • Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression. 
  • Transgenic tubular cell expression of class II is insufficient to initiate immune renal injury. 
  • Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion. 
  • Transport interactions of cystine and dibasic amino acids in isolated rat renal tubules. 
  • Tubular Secretion in CKD. 
  • Tubular markers are associated with decline in kidney function in proteinuric type 2 diabetic patients. 
  • Tubulovascular cross-talk by vascular endothelial growth factor a maintains peritubular microvasculature in kidney. 
  • Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression. 
  • Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice. 
  • Utilization of the chick chorioallantoic membrane for in vitro growth of the embryonic murine kidney. 
  • Variant of Bartter's syndrome with a distal tubular rather than loop of Henle defect. 
  • Vasoconstrictor responses in thromboxane receptor knockout mice: tubuloglomerular feedback and ureteral obstruction. 
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  Keywords of People

  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology