Killer Cells, Natural

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  Subject Areas on Research

  • 2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis. 
  • A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues. 
  • A pilot study of high-intensity interval training in older adults with treatment naïve chronic lymphocytic leukemia. 
  • A prognostic index for natural killer cell lymphoma after non-anthracycline-based treatment: a multicentre, retrospective analysis. 
  • A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. 
  • A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model. 
  • A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. 
  • Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-Infected Lymph Nodes Associated with In Situ Differentiation and Functional Anergy. 
  • Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth. 
  • Active lifestyle offsets HRT-induced suppression of T cell reactivity to mitogens. 
  • Acute Liver Damage Associated with Innate Immune Activation in a Small Nonhuman Primate Model of Hepacivirus Infection. 
  • Adaptive NK cell responses in HIV/SIV infections: A roadmap to cell-based therapeutics? 
  • Advances in the understanding and treatment of human severe combined immunodeficiency. 
  • Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood. 
  • Alemtuzumab for the prevention and treatment of graft-versus-host disease. 
  • Alpha-glycosylceramides enhance the antitumor cytotoxicity of hepatic lymphocytes obtained from cancer patients by activating CD3-CD56+ NK cells in vitro. 
  • Alterations in antibody-dependent cellular cytotoxicity during the course of HIV-1 infection. Humoral and cellular defects. 
  • An integrative model using flow cytometry identifies nosocomial infection after trauma. 
  • Analysis of the immune responses in chimpanzees infected with HIV type 1 isolates. 
  • Analysis of the linker for activation of T cells (LAT) and the linker for activation of B cells (LAB) in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire. 
  • Analysis of the relationship between stage of differentiation and NK/LAK susceptibility of colon carcinoma cells. 
  • Anti-HIV-1 ADCC: clinical and therapeutic implications. 
  • Anti-glycoprotein D monoclonal antibody protects against herpes simplex virus type 1-induced diseases in mice functionally depleted of selected T-cell subsets or asialo GM1+ cells. 
  • Anti-phosphorylcholine-opsonized low-density lipoprotein promotes rapid production of proinflammatory cytokines by dendritic cells and natural killer cells. 
  • Anti-self HLA may be clonally expressed. 
  • Antigen-specific NK cell memory in rhesus macaques. 
  • Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay. 
  • Are the salutogenic effects of social supports modified by income? A test of an "added value hypothesis". 
  • Autologous lymph node cell-derived tumor-specific cytotoxic T-cells for use in adoptive immunotherapy of human melanoma. 
  • Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. 
  • Breast cancer patients have improved immune and neuroendocrine functions following massage therapy. 
  • CALGB 150905 (Alliance): rituximab broadens the antilymphoma response by activating unlicensed NK cells. 
  • CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver. 
  • CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques. 
  • Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface? 
  • Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology. 
  • Caspase-7 activates ASM to repair gasdermin and perforin pores. 
  • Cellular anti-GP120 cytolytic reactivities in HIV-1 seropositive individuals. 
  • Changes in immune parameters seen in Gulf War veterans but not in civilians with chronic fatigue syndrome. 
  • Characterization of Rhesus Macaque Liver-Resident CD49a+ NK Cells During Retrovirus Infections. 
  • Characterization of cord blood natural killer and lymphokine activated killer lymphocytes following ex vivo cellular engineering. 
  • Characterization of cytotoxic cells generated from in vitro cultures of murine bone marrow cells. 
  • Characterization of uterine NK cells in women with infertility or recurrent pregnancy loss and associated endometriosis. 
  • Circulating T-Cell Subsets, Monocytes, and Natural Killer Cells in Peripartum Cardiomyopathy: Results From the Multicenter IPAC Study. 
  • Circulating natural killer cell phenotypes in men and women with major depression. Relation to cytotoxic activity and severity of depression. 
  • Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogeneic bone marrow transplantation. 
  • Clinical application of whole-genome sequencing in patients with primary immunodeficiency. 
  • Cloning of murine splenic T lymphocytes and natural killer (NK) cells on filter paper discs: detection of a novel NK/T phenotype. 
  • Combination treatment of murine tumors by adenovirus-mediated local B7/IL12 immunotherapy and radiotherapy. 
  • Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. 
  • Contrasting effects of centromedial and basolateral amygdaloid lesions on stress-related responses in the rat. 
  • Copy number variation of KIR genes influences HIV-1 control. 
  • Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model. 
  • Costimulation, coinhibition and cancer. 
  • Costimulatory molecules are active in the human xenoreactive T-cell response but not in natural killer-mediated cytotoxicity. 
  • Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. 
  • Cutting edge: a role for the adaptor protein LAT in human NK cell-mediated cytotoxicity. 
  • Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity. 
  • Cytomegalovirus as an immunomodulator across the lifespan. 
  • Decreased normal NK-cells is a characteristic of T-cell large granular lymphocytic leukemia and is strongly associated with cytopenia. 
  • Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. 
  • Defective antitumor responses in CX3CR1-deficient mice. 
  • Deficient antibody-dependent cellular cytotoxicity against human immunodeficiency virus (HIV)-expressing target cells in perinatal HIV infection. 
  • Definition of a novel cellular constituent of the bone marrow that regulates the response of immature B cells to B cell antigen receptor engagement. 
  • Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta. 
  • Dendritic cells stimulated with Actinobacillus actinomycetemcomitans elicit rapid gamma interferon responses by natural killer cells. 
  • Dendritic cells/natural killer cross-talk: a novel target for human immunodeficiency virus type-1 protease inhibitors. 
  • Dendritic-NK cell interactions in P. gingivalis-specific responses. 
  • Determination of CD4 and CD8 lymphocyte subsets by a new alternative fluorescence immunoassay. 
  • Development and distribution of a human B cell subpopulation identified by the HB-4 monoclonal antibody. 
  • Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation. 
  • Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. 
  • Differential requirement for the SAP-Fyn interaction during NK T cell development and function. 
  • Direct ultrastructural evidence of target-directed polarization by cytotoxic lymphocytes in lesions of human graft-vs-host disease. 
  • Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34. 
  • Donor type natural killer cells after haploidentical T cell-depleted bone marrow stem cell transplantation in a patient with adenosine deaminase-deficient severe combined immunodeficiency. 
  • EL-4 metastases in spleen and bone marrow suppress the NK activity generated in these organs. 
  • Early Endometriosis in Females Is Directed by Immune-Mediated Estrogen Receptor α and IL-6 Cross-Talk. 
  • Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection. 
  • Early-onset monocyte-B-natural killer-dendritic cells' deficiency successfully treated with hematopoietic stem cell transplantation. 
  • Effect of high doses of intravenously administered immune globulin on natural killer cell activity in peripheral blood. 
  • Effector mechanisms in transplant rejection. 
  • Effects of one year of supplementation with zinc and other micronutrients on cellular immunity in the elderly. 
  • Effects of pretransplant splenectomy and immunosuppression of humoral immunity in a pig-to-newborn goat cardiac xenograft model. 
  • Efficacy and Safety of a Pegasparaginase-Based Chemotherapy Regimen vs an L-asparaginase-Based Chemotherapy Regimen for Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized Clinical Trial. 
  • Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: soluble L-selectin levels indicate disease severity. 
  • Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers. 
  • Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition. 
  • Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases. 
  • Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorders. 
  • Erythema nodosum in a patient with renal cell carcinoma treated with interleukin 2 and lymphokine-activated killer cells. 
  • Essential role of LAT in T cell development. 
  • Evaluation of immune responses to porcine reproductive and respiratory syndrome virus in pigs during early stage of infection under farm conditions. 
  • Ex vivo expanded human CD4+ regulatory NKT cells suppress expansion of tumor antigen-specific CTLs. 
  • Ex vivo spermine dialdehyde treatment prevents lethal GVHD in a murine bone marrow transplantation model. 
  • Expansions of NK-like αβT cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells. 
  • Expression of C3b receptors on human be cells and myelomonocytic cells but not natural killer cells. 
  • Expression of surface CD1d in the extravillous trophoblast cells of early gestational placenta is downregulated in a manner dependent on trophoblast differentiation. 
  • Expression, distribution, and biochemistry of human CD39. Role in activation-associated homotypic adhesion of lymphocytes. 
  • Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020. 
  • Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques. 
  • Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif. 
  • GP120 specific cellular cytotoxicity in HIV-1 seropositive individuals. Evidence for circulating CD16+ effector cells armed in vivo with cytophilic antibody. 
  • GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression. 
  • Gaining insights into chronic natural killer cell leukemias through extensive characterization of an individual case. 
  • Gene therapy for human SCID: dreams become reality. 
  • Genome-scale screens identify factors regulating tumor cell responses to natural killer cells. 
  • Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo. 
  • Granulocyte-macrophage colony-stimulating factor and interleukin-3 mRNAs are produced by a small fraction of blood mononuclear cells. 
  • Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. 
  • Graves' disease after interleukin-2 therapy in a patient with human immunodeficiency virus infection. 
  • H5-type influenza virus hemagglutinin is functionally recognized by the natural killer-activating receptor NKp44. 
  • HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition. 
  • HLA-C and liver transplant outcomes: interpreting the facts. 
  • Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. 
  • Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation. 
  • Hepatosplenic T-Cell Lymphoma: A Clinicopathologic Review With an Emphasis on Diagnostic Differentiation From Other T-Cell/Natural Killer-Cell Neoplasms. 
  • Herpes simplex virus blocks intracellular transport of HLA-G in placentally derived human cells. 
  • High versus low basal cortisol secretion in asymptomatic, medication-free HIV-infected men: differential effects of severe life stress on parameters of immune status. 
  • High-dose human lymphoblastoid interferon in metastatic colorectal cancer: clinical results and modification of biological responses. 
  • High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses. 
  • Holding back: HLA-associated inhibition of NK cells gives HIV a leg up. 
  • Human cytotoxic T cells specific for autologous melanoma cells: successful generation from lymph node cells in seven consecutive cases. 
  • Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. I. Characterization of the lymphocyte subset reactive with B73.1. 
  • Human natural killer cells do not inhibit growth of Cryptococcus neoformans in the absence of antibody. 
  • Human placental cytotrophoblasts attract monocytes and CD56(bright) natural killer cells via the actions of monocyte inflammatory protein 1alpha. 
  • Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPs. 
  • Hyperinflammation, T cells, and endotoxemia. 
  • IL-10 stimulatory effects on human NK cells explored by gene profile analysis. 
  • IL-2-dependent adaptive control of NK cell homeostasis. 
  • IL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells. 
  • Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans. 
  • IgE Fc receptor positive T, B and NK cells in patients with the hyper-IgE syndrome. 
  • Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL. 
  • Immune correlates of HIV-1 reservoir cell decline in early-treated infants. 
  • Immune interactions at the maternal-fetal interface: a focus on antigen presentation. 
  • Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. 
  • Immunity of patients surviving 20 to 30 years after allogeneic or syngeneic bone marrow transplantation. 
  • Immunogenic determinants of a neuropathogenic murine leukemia virus. 
  • Immunologic control of a retrovirus-associated murine adenocarcinoma. VIII. Corynebacterium parvum-activated natural killer cells as potent antibody-dependent cell-mediated cytotoxicity effectors. 
  • Immunology. Outwitted by viral RNAs. 
  • Immunotherapy Gone Viral: Bortezomib and oHSV Enhance Antitumor NK-Cell Activity. 
  • Immunotherapy of B-cell malignancies with genetically engineered human CD8+ natural killer T cells. 
  • Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study. 
  • Impact of exercise on the immune system and outcomes in hematologic malignancies. 
  • Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies. 
  • Indirect activation of rhesus macaque (Macaca mulatta) NK cells in oral and mucosal draining lymph nodes. 
  • Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium. 
  • Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections. 
  • Inhibition of human natural killer cell activity by a synthetic peptide homologous to a conserved region in the retroviral protein, p15E. 
  • Interferon-γ-secreting NK cells promote induction of dry eye disease. 
  • Interleukin-15 enhances the secretion of IFN-gamma and CC chemokines by natural killer cells from HIV viremic and aviremic patients. 
  • Interleukin-15 receptor blockade in non-human primate kidney transplantation. 
  • Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo. 
  • Interleukin-2 immunotherapy of murine cytomegalovirus retinitis during MAIDS correlates with increased intraocular CD8+ T-cell infiltration. 
  • Interleukin-7 receptor alpha is essential for the development of gamma delta + T cells, but not natural killer cells. 
  • Intrathecal morphine suppresses immune function in rats with inflammatory-induced pain. 
  • Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency. 
  • Involvement of histo-blood-group antigens in the susceptibility of colon carcinoma cells to natural killer-mediated cytotoxicity. 
  • Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation. 
  • Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1. 
  • Lack of generation of killer cells in the mixed lymphocyte reaction between mitogen-stimulated and unstimulated autologous lymphocytes. 
  • Landscape of stimulation-responsive chromatin across diverse human immune cells. 
  • Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells. 
  • Leveraging Natural Killer Cell Innate Immunity against Hematologic Malignancies: From Stem Cell Transplant to Adoptive Transfer and Beyond. 
  • Ligand-independent toll-like receptor signals generated by ectopic overexpression of MyD88 generate local and systemic antitumor immunity. 
  • Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: evaluation in normal and pathological conditions. 
  • Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4(+)/CD25(+) T cells. 
  • Long-term efficacy of enzyme replacement therapy for adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID). 
  • Long-term killing of natural killer-resistant target cells by interferon-alpha-, interferon-gamma-, and interleukin-2-activated natural killer cells. 
  • Longitudinal peripheral blood lymphocyte subsets correlate with decreased disease activity in juvenile dermatomyositis. 
  • Loss of tumorigenicity following in vitro MuLV infection is associated with induction of peritoneal natural killer cell activity. 
  • Ly49-dependent NK cell licensing and effector inhibition involve the same interaction site on MHC ligands. 
  • Lymphocyte and monocyte subset changes during cardiopulmonary bypass: effects of aging and gender. 
  • Lymphocyte subsets in Chediak-Higashi patients. 
  • Measurement of direct and indirect forms of anti-HIV-1 ADCC: implications for other retroviral disease. 
  • Mechanism of the anti-tumour effect of biochemotherapy in melanoma: preliminary results. 
  • Mixed-phenotype large granular lymphocytic leukemia: a rare subtype in the large granular lymphocytic leukemia spectrum. 
  • Modulation of MICA on the surface of Chlamydia trachomatis-infected endocervical epithelial cells promotes NK cell-mediated killing. 
  • Monkeying Around: Using Non-human Primate Models to Study NK Cell Biology in HIV Infections. 
  • Monoclonal Antibodies, Derived from Humans Vaccinated with the RV144 HIV Vaccine Containing the HVEM Binding Domain of Herpes Simplex Virus (HSV) Glycoprotein D, Neutralize HSV Infection, Mediate Antibody-Dependent Cellular Cytotoxicity, and Protect Mice from Ocular Challenge with HSV-1. 
  • Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity. 
  • Mucosal-homing natural killer cells are associated with aging in persons living with HIV. 
  • Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development. 
  • Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity. 
  • Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system. 
  • Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. 
  • NK and LAK susceptibility varies inversely with target cell MHC class I antigen expression in a rat epithelial tumour system. 
  • NK cell activation by dendritic cell vaccine: a mechanism of action for clinical activity. 
  • NK cell recruitment limits tissue damage during an enteric helminth infection. 
  • NK susceptibility varies inversely with target cell class I HLA antigen expression. 
  • NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway. 
  • NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. 
  • Nanoparticle Encapsulation of Synergistic Immune Agonists Enables Systemic Codelivery to Tumor Sites and IFNβ-Driven Antitumor Immunity. 
  • Natural killer cell activity and prostate cancer risk in veteran men undergoing prostate biopsy. 
  • Natural killer cell infection and inactivation in vitro by the human immunodeficiency virus. 
  • Natural killer cell mobilization and egress following acute exercise in men with prostate cancer. 
  • Natural killer cell-endothelial cell interactions in xenotransplantation. 
  • Natural killer cell-enriched donor lymphocyte infusions from A 3-6/6 HLA matched family member following nonmyeloablative allogeneic stem cell transplantation. 
  • Natural killer cells and lymphocytes increase in women with breast cancer following massage therapy. 
  • Natural killer cells in vernal keratoconjunctivitis. 
  • Natural killing in immunodeficient patients. 
  • Natural killing target antigens as inducers of interferon: studies with an immunoselected, natural killing-resistant human T lymphoblastoid cell line. 
  • Natural-killer-cell function and bone marrow transplantation. 
  • Non-linear multidimensional flow cytometry analyses delineate NK cell phenotypes in normal and HIV-infected chimpanzees. 
  • Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis. 
  • Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients. 
  • Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1. 
  • Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity. 
  • Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells. 
  • Osteopontin has a protective role in prostate tumor development in mice. 
  • Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity. 
  • Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge. 
  • Peripheral blood dendritic cells, but not monocyte-derived dendritic cells, can augment human NK cell function. 
  • Phase I studies of interleukin (IL)-2 and rituximab in B-cell non-hodgkin's lymphoma: IL-2 mediated natural killer cell expansion correlations with clinical response. 
  • Phase I studies of recombinant interferon-gamma. 
  • Phase I study of pharmacological and immunological effects of human lymphoblastoid interferon given to patients with cancer. 
  • Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes. 
  • Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL). 
  • Porcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigs. 
  • Positively selected Leu-11a (CD16+) cells require the presence of accessory cells or factors for the lysis of herpes simplex virus-infected fibroblasts but not herpes simplex virus-infected Raji. 
  • Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420. 
  • Potent functional antibody responses elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults. 
  • Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer. 
  • Preservation of motor function by inhibition of CD8+ virus peptide-specific T cells in Theiler's virus infection. 
  • Primate renal transplants using immunotoxin. 
  • Prolonged discordant xenograft survival and delayed xenograft rejection in a pig-to-baboon orthotopic cardiac xenograft model. 
  • Prospects for treatment of human retrovirus-associated diseases. 
  • Psychosocial stress moderates the relationship of cancer history with natural killer cell activity. 
  • RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. 
  • RAB11FIP5-Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures. 
  • Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model. 
  • Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules. 
  • Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1. 
  • Relationship between sensitivity to natural killer cells and MHC class-I antigen expression in colon carcinoma cell lines. 
  • Resistance of pancreatic carcinoma cells is reversed by coculturing NK-like T cells with dendritic cells pulsed with tumor-derived RNA and CA 19-9. 
  • Role of natural killer cell function in dendritic cell-based vaccines. 
  • SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity. 
  • Selective inhibition of natural killer activity by the monoclonal antibodies OKT10 and VEP10 at the single cell level. 
  • Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2. 
  • Self-discrepancy and natural killer cell activity: immunological consequences of negative self-evaluation. 
  • Self-regulatory cognition and immune reactivity: idiographic success and failure feedback effects on the natural killer cell. 
  • Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells. 
  • Serum concentrations of soluble human leukocyte class I antigens and of the soluble intercellular adhesion molecule-1 in endometriosis: relationship with stage and non-pigmented peritoneal lesions. 
  • Severe combined immunodeficiency (SCID) with natural killer (NK) cell predominance. 
  • Severe combined immunodeficiency with natural killer-cell predominance: abrogation of graft-versus-host disease and immunologic reconstitution with HLA-identical bone marrow cells. 
  • Shifting Paradigms in Allergic Contact Dermatitis: The Role of Innate Immunity. 
  • Simian Immunodeficiency Virus Infection Modulates CD94+ (KLRD1+) NK Cells in Rhesus Macaques. 
  • Skipped Over: Tuning Natural Killer Cells Toward HIV Through Alternative Splicing. 
  • Somatic mosaicism caused by monoallelic reversion of a mutation in T cells of a patient with ADA-SCID and the effects of enzyme replacement therapy on the revertant phenotype. 
  • Study of the role of CCR5 in a mouse model of intranasal challenge with Yersinia pestis. 
  • Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system. 
  • Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin. 
  • T cell-mediated elimination of B7.2 transgenic B cells. 
  • T lymphocyte ontogeny in adenosine deaminase-deficient severe combined immune deficiency after treatment with polyethylene glycol-modified adenosine deaminase. 
  • T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex. 
  • T-cell and T/natural killer-cell lymphomas involving ocular and ocular adnexal tissues: a clinicopathologic, immunohistochemical, and molecular study of seven cases. 
  • TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity. 
  • TRIGGERED: could refocused cell signaling be key to natural killer cell-based HIV immunotherapeutics? 
  • The chemokine CX3CL1 regulates NK cell activity in vivo. 
  • The dual role of IL-10. 
  • The effect of AZT on in vitro lymphokine-activated killer (LAK) activity in human immunodeficiency virus type-1 (HIV-1) infected individuals. 
  • The effect of natural killer cell killer Ig-like receptor alloreactivity on the outcome of bone marrow stem cell transplantation for severe combined immunodeficiency (SCID). 
  • The effects of donor-specific blood transfusion enhancement of rat renal allografts on cytotoxic activity and phenotypes of peripheral blood lymphocytes, splenocytes, and graft-infiltrating cells. 
  • The effects of donor-specific blood transfusion enhancement of rat renal allografts on host NK cell responses. 
  • The fetal allograft revisited: does the study of an ancient invertebrate species shed light on the role of natural killer cells at the maternal-fetal interface? 
  • The functional diversity of tissue-resident natural killer cells against infection. 
  • The host defense peptide cathelicidin is required for NK cell-mediated suppression of tumor growth. 
  • The immune system in aging: roles of cytokines, T cells and NK cells. 
  • The impact of HIV-1 infection on phenotypic and functional parameters of cellular immunity in chimpanzees. 
  • The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors. 
  • The role of natural killer (NK) cells and NK cell receptor polymorphisms in the assessment of HIV-1 neutralization. 
  • The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities. 
  • The value of [(18)F]fluorodeoxyglucose positron emission tomography/computed tomography in extranodal natural killer/T-cell lymphoma. 
  • Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes. 
  • Thymoma-associated immunodeficiency: a syndrome characterized by severe alterations in NK, T and B-cells and progressive increase in naïve CD8+ T Cells. 
  • Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques. 
  • Transduction of human melanoma cells with the gamma interferon gene enhances cellular immunity. 
  • Tumor necrosis factor, natural killer activity and other measures of immune function and inflammation in elderly men with heart failure. 
  • Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia. 
  • Uterine NK cell education: Learning the ropes in pregnancy. 
  • Vaccine-Induced Antibodies Mediate Higher Antibody-Dependent Cellular Cytotoxicity After Interleukin-15 Pretreatment of Natural Killer Effector Cells. 
  • Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells. 
  • Viral subversion of the immune system. 
  • Why newborn screening for severe combined immunodeficiency is essential: a case report. 
  • X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity. 
  • X-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses. 
  • [Antitumoral action of interferons and interleukins in combination with radiotherapy. Part I: immunologic basis]. 
  • [Effect of intrathecal pumping morphine on immunological function in rats with formalin pain]. 
  • [Effect of intrathecal pumping tramadol on the immune function in rats with formalin pain]. 
  • mTORC2 in Thymic Epithelial Cells Controls Thymopoiesis and T Cell Development. 
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  Keywords of People

  • Buckley, Rebecca Hatcher, Professor Emeritus of Pediatrics, Pediatrics, Allergy and Immunology
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Immunology
  • Shinohara, Mari L., Associate Professor of Immunology, Cell Biology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Immunology
  • Zhong, Xiaoping, Professor of Pediatrics, Immunology