Leukapheresis
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Subject Areas on Research
- A comparative study of the generation of dendritic cells from mobilized peripheral blood progenitor cells of patients undergoing high-dose chemotherapy.
- A functional tethered ligand thrombin receptor is present on human hematopoietic progenitor cells.
- A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.
- A randomized phase 3 study of peripheral blood progenitor cell mobilization with stem cell factor and filgrastim in high-risk breast cancer patients.
- Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins.
- Combination immunotherapy with clinical-scale enriched human gammadelta T cells, hu14.18 antibody, and the immunocytokine Fc-IL7 in disseminated neuroblastoma.
- Do white cells in stored blood components reduce the likelihood of posttransfusion bacterial sepsis?
- Effects of granulocyte-macrophage colony stimulating factor produced in Chinese hamster ovary cells (regramostim), Escherichia coli (molgramostim) and yeast (sargramostim) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy.
- Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
- Evaluation of Hematopoietic Stem Cell Mobilization Rates with Early Plerixafor Administration for Adult Stem Cell Transplantation.
- Evaluation of the spectra Optia® mononuclear cell collection procedure in multiple myeloma patients.
- Ex vivo generation of dendritic cells from cryopreserved, post-induction chemotherapy, mobilized leukapheresis from pediatric patients with medulloblastoma.
- Graft survival in a rhesus renal transplant model after immunotoxin-mediated T-cell depletion is enhanced by mycophenolate and steroids.
- Human gammadelta T cells from G-CSF-mobilized donors retain strong tumoricidal activity and produce immunomodulatory cytokines after clinical-scale isolation.
- Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA.
- Impairment of filgrastim-induced stem cell mobilization after prior lenalidomide in patients with multiple myeloma.
- In vivo and in vitro characteristics of double units of RBCs collected by apheresis with a single in-line WBC-reduction filter.
- Incidence of tumor-cell contamination in leukapheresis products of breast cancer patients mobilized with stem cell factor and granulocyte colony-stimulating factor (G-CSF) or with G-CSF alone.
- Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs.
- Leukopheresis therapy of leukemic reticuloendotheliosis (hairy cell leukemia).
- Mobilization of dendritic cells from patients with breast cancer into peripheral blood stem cell leukapheresis samples using Flt-3-Ligand and G-CSF or GM-CSF.
- Mobilization of dendritic cells in cancer patients treated with granulocyte colony-stimulating factor and chemotherapy.
- Mobilization, collection, and processing of autologous peripheral blood stem cells: development of a clinical process with associated costs.
- Mobilized peripheral blood SSCloALDHbr cells have the phenotypic and functional properties of primitive haematopoietic cells and their number correlates with engraftment following autologous transplantation.
- Multiple cycles of high dose chemotherapy supported by hematopoietic progenitor cells as treatment for patients with advanced malignancies.
- Optimizing the efficiency and quality of sipuleucel-T delivery in an academic institution.
- Pediatric large-volume leukapheresis: a single institution experience with heparin versus citrate-based anticoagulant regimens.
- Peripheral blood progenitor cell mobilization using stem cell factor in combination with filgrastim in breast cancer patients.
- Peripheral blood stem cell harvesting and CD34-positive cell selection.
- Peripheral blood stem cell transplantation in breast cancer.
- Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma.
- Preparation of peptide-loaded dendritic cells for cancer immunotherapy.
- Prestorage leukoreduction prevents accumulation of matrix metalloproteinase 9 in stored blood.
- Results of a Phase I study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children with Stage 4 neuroblastoma.
- Safety of growth factor administration for leukapheresis in those with WBC counts greater than 60,000/µl.
- Sources of human and murine hematopoietic stem cells.
- Systemic interleukin-2 and adoptive transfer of lymphokine-activated killer cells improves antibody-dependent cellular cytotoxicity in patients with relapsed B-cell lymphoma treated with rituximab.
- The significance of microbial cultures of the hematopoietic support for patients receiving high-dose chemotherapy.
- Thrombocytopenia in allogeneic peripheral blood stem cell collections.