Leukemia, Experimental
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Subject Areas on Research
- Absence of macrophage involvement in the passive serum therapy of Friend leukemia virus-induced disease.
- Acute lymphoblastic leukemia: classification and characterization with antisera to human T-cell and Ia antigens.
- Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica.
- CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation.
- CD4+Thy1- thymocytes with a Th-type 2 cytokine response.
- Comparison of in vitro and in vivo differentiation of myeloblastic leukemia of the RFM/Un mouse.
- Cooperative effects of gamma interferon and 1-alpha,25-dihydroxyvitamin D3 in inducing differentiation of human promyelocytic leukemia (HL-60) cells.
- Dibutyryl cyclic adenosine monophosphate reduces expression of c-myc during HL-60 differentiation.
- Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells.
- Effect of interferon on murine leukemia virus infection. II. Synthesis of viral components in exogenous infection.
- Evaluation of arylmethylaminopropanediols by a novel in vitro pharmacodynamic assay: correlation with antitumor activity in vivo.
- Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant.
- Further characterization of the oncornavirus inactivating factor in normal mouse serum.
- IFN-gamma production in response to neuropathogenic Cas-Br-M murine leukemia virus infection.
- Immuno-prophylaxis and -therapy of C-type oncorna viral diseases in mice and cats.
- Immunotherapy of murine leukemia. II. Effect of passive serum therapy on Friend murine leukemia virus-induced hematologic and coagulation parameters.
- Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3.
- In vivo lysis of L5178Y cells in the establishment of the tumor-dormant state in DBA/2 mice.
- Inducers of Friend leukaemic cell differentiation in vitro--effects of in vivo administration.
- Influence of antisera to oncornavirus glycoprotein (gp71) on infections of cats with feline leukemia virus.
- Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.
- Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program.
- Ion fluxes and differentiation in transformed cell lines.
- Leukocyte chemoattraction by 1,2-diacylglycerol.
- Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice.
- Macrophage accumulation in mice is inhibited by low molecular weight products from murine leukemia viruses.
- Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation.
- MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice.
- Microassay for the photometric quantitation of cell-associated plasminogen activator using a chromogenic tripeptide substrate.
- Neonate-primed CD8+ memory cells rival adult-primed memory cells in antigen-driven expansion and anti-viral protection.
- Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.
- P-glycoprotein mediated resistance to 5'-nor-anhydro-vinblastine (Navelbine).
- PG27, an extract of Tripterygium wilfordii hook f, induces antigen-specific tolerance in bone marrow transplantation in mice.
- Phospholipid membrane stabilization by dimethylsulfoxide and other inducers of Friend leukemic cell differentiation.
- Properties of mouse leukemia viruses. XIII. Serum therapy of virus-induced murine leukemias.
- Properties of mouse leukemia viruses. XIX. Effective antibody therapy of AKR leukemia occurs independently of virus neutralization and produces long-term changes in the virus status of the thymus.
- Properties of mouse leukemia viruses. XVI. Suppression of spontaneous fetal leukemias in AKR mice by treatment with broadly reacting antibody against the viral glycoprotein gp 71.
- Properties of mouse leukemia viruses. XVII. Factors required for successful treatment of spontaneous AKR leukemia by antibodies against gp71.
- Properties of mouse leukemia viruses: XX. Variation of AKR Substrains in response to antibody therapy.
- Retroviral protein P15E and tumorigenesis. Expression is neither required nor sufficient for tumor development.
- Role of antibodies to murine leukemia virus p15E transmembrane protein in immunotherapy against AKR leukemia: a model for studies in human acquired immunodeficiency syndrome.
- Spermine dialdehyde, a novel ex vivo purging agent for both allogenic and autologous bone marrow transplantations.
- Suppression of leukaemia virus pathogenicity by polyoma virus enhancers.
- The effects of leukemosuppressive immunotherapy on bone marrow infectious cell centers in AKR mice.
- The effects of leukemosuppressive immunotherapy on thymic infectious cell centers in AKR mice.
- The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein.
- The role of bone marrow and thymic elements in the initiation and spread of virus production in the AKR thymus.
- Tumor cell killing by phorbol ester--differentiated human leukemia cells.
- Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.
- Use of etoposide in combination with cyclosporin for purging multidrug-resistant leukemic cells from bone marrow in a mouse model.
- Visible light photochemical release of nitric oxide from S-nitrosoglutathione: potential photochemotherapeutic applications.
- XVIII. Effective treatment of AKR leukemia with antibody to gp7 1 eliminates the neonatal burst of ecotropic AKR virus producing cells.
- [Stimulation of immunoreactivity against endogenous retroviruses and protection against leukemia in aged AKR mice after vaccination with antibodies to viral surface components. The role of antibodies to p15(E)].
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Keywords of People
- Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
- Lee, Chang Lung, Assistant Professor in Radiation Oncology, Pathology