Leukocytes

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  Subject Areas on Research

  • 5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors. 
  • A 3D numerical study of the effect of channel height on leukocyte deformation and adhesion in parallel-plate flow chambers. 
  • A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. 
  • A North American multilaboratory study of CD4 counts using flow cytometric panLeukogating (PLG): a NIAID-DAIDS Immunology Quality Assessment Program Study. 
  • A chemotactic factor for mononuclear leukocytes. 
  • A comparison of the leukocyte agglutination and mixed agglutination techniques for detecting human tissue isoantigens. 
  • A functional role for circulating mouse L-selectin in regulating leukocyte/endothelial cell interactions in vivo. 
  • A human mononuclear leukocyte chemotactic factor: characterization, specificity and kinetics of production by homologous leukocytes. 
  • A new twist to the leukocyte adhesion cascade: intimate cooperation is key. 
  • A novel beta-globin mutation, beta Durham-NC [beta 114 Leu-->Pro], produces a dominant thalassemia-like phenotype. 
  • A prospective clinical and pathological examination of injection site reactions with the HIV-1 fusion inhibitor enfuvirtide. 
  • A randomized study comparing leukocyte-depleted versus packed red cell transfusions in prospective cadaver renal allograft recipients. 
  • Abnormalities of chemotactic lymphokine synthesis and mononuclear leukocyte chemotaxis in Wiskott-Aldrich syndrome. 
  • Abnormalities of leukocyte chemotaxis in human disease. 
  • Accelerated rejection of skin grafts in recipients sensitized with extracted human histocompatibility antigens. 
  • Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosol. 
  • Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis. 
  • Adhesion molecule cascades direct lymphocyte recirculation and leukocyte migration during inflammation. 
  • Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease. 
  • Age-related alterations in actin cytoskeleton and receptor expression in human leukocytes. 
  • Alterations in soluble and leukocyte surface L-selectin (CD 62L) in hemodialysis patients. 
  • Analysis of Fc gamma receptors on human peripheral blood leukocytes by flow microfluorometry. I. Receptor distributions on monocytes, T gamma cells and cells labeled with the 3Al anti-T cell monoclonal antibody. 
  • Anomalous MLR responsiveness among siblings. 
  • Antibody binding to a conformation-dependent epitope induces L-selectin association with the detergent-resistant cytoskeleton. 
  • Antibody-dependent cellular cytotoxicity in primary immunodeficiency diseases and with normal leukocyte subpopulations. Importance of the type of target. 
  • Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition. 
  • Application of a Novel Murine Ear Vein Model to Evaluate the Effects of a Vascular Radioprotectant on Radiation-Induced Vascular Permeability and Leukocyte Adhesion. 
  • Assessment of candidate ocular biomarkers of ageing in a South African adult population: relationship with chronological age and systemic biomarkers. 
  • Association of Leukocyte Telomere Length With Mortality Among Adult Participants in 3 Longitudinal Studies. 
  • Association of psychosocial factors with leukocyte telomere length among African Americans in the Jackson Heart Study. 
  • Autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly) is linked to chromosome 22q12-13. 
  • Bioactive hydrogel substrates: probing leukocyte receptor-ligand interactions in parallel plate flow chamber studies. 
  • Biochemical changes in leukocytes in response to chemoattractants. 
  • Biological activity of complement in vivo. Role of C5 in the accumulation of polymorphonuclear leukocytes in inflammatory exudates. 
  • Biology of cerebral arteriovenous malformations with a focus on inflammation. 
  • Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes. 
  • Brief communication: melanoma-specific antibodies produced in monkeys by immunization with human melanoma cell lines. 
  • Bromelain treatment alters leukocyte expression of cell surface molecules involved in cellular adhesion and activation. 
  • CD antigens 1993. 
  • CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion. 
  • Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs. 
  • Cardiopulmonary bypass induces leukocyte-platelet adhesion. 
  • Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. 
  • Cell biology. Propelling progeny. 
  • Cellular adhesion and proliferative responses of neonatal human lymphocytes to pig endothelial cells. 
  • Cerebrospinal fluid findings in children with fever-associated status epilepticus: results of the consequences of prolonged febrile seizures (FEBSTAT) study. 
  • Chemoattractant receptor cross-desensitization. 
  • Chemokine ligand and receptor expression in the pregnant uterus: reciprocal patterns in complementary cell subsets suggest functional roles. 
  • Chemotaxis of inflammatory cells. 
  • Circulating Tumor Cell Phenotyping via High-Throughput Acoustic Separation. 
  • Clinical implications of aneuploid cytogenetic profiles in adult acute leukemia. 
  • Cloning and characterization of the major promoter of the human protein kinase C beta gene. Regulation by phorbol esters. 
  • Collagenase: its physiological and pathological role. 
  • Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions. 
  • Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. 
  • Comparisons of mixed leukocyte reactions with skin graft survival in families genotyped for HL-A. 
  • Comprehensive analysis of commercially available mouse antichicken monoclonal antibodies for cross-reactivity with peripheral blood leukocytes from commercial turkeys. 
  • Contemporary testing for enteric pathogens: the potential for cost, time, and health care savings. 
  • Cost-effectiveness of white cell-reduction filters in treatment of adult acute myelogenous leukemia. 
  • Costimulation, coinhibition and cancer. 
  • Cytokine deposition alters leukocyte morphology and initial recruitment of monocytes and γδT cells after corneal injury. 
  • Cytokines and inflammatory factors regulating immunoglobulin production in aggressive periodontitis. 
  • Daily physical activity is negatively associated with thyroid hormone levels, inflammation, and immune system markers among men and women in the NHANES dataset. 
  • Decreased expression levels of L-selectin on subsets of leucocytes and increased serum L-selectin in severe psoriasis. 
  • Degradation of collagen by a human granulocyte collagenolytic system. 
  • Delineation of the role of platelet-activating factor in the immunoglobulin G2 antibody response. 
  • Depletion of passenger leukocytes from corneal grafts: an effective means of promoting transplant survival? 
  • Developmental allometry and paediatric malaria. 
  • Diagnosis and management of myeloproliferative disorders. 
  • Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation. 
  • Differential regulation of leucocyte L-selectin (CD62L) expression in normal lymphoid and inflamed extralymphoid tissues. 
  • Diminished leukocyte-endothelium interaction in tumor microvessels. 
  • Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes. 
  • Distinct expression patterns of CD123 and CD34 on normal bone marrow B-cell precursors ("hematogones") and B lymphoblastic leukemia blasts. 
  • Double agents in the war on cancer: leukocytes govern ovarian cancer progression. 
  • Doyne Lecture. The pathology of the outflow system in primary and secondary glaucoma. 
  • ELISA for quantitation of L-selectin shed from leukocytes in vivo. 
  • Early-life exposure to famine and late-life depression: Does leukocyte telomere length mediate the association? 
  • Effect of C4 depletion on the utilization of the terminal components of guinea-pig complement by endotoxin. 
  • Effect of a metalloporphyrin antioxidant (MnTE-2-PyP) on the response of a mouse prostate cancer model to radiation. 
  • Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial. 
  • Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation. 
  • Effect of streptavidin-biotin on endothelial vasoregulation and leukocyte adhesion. 
  • Effect of topical azithromycin on corneal innate immune responses. 
  • Effects of age and parasitemia on nitric oxide production/leukocyte nitric oxide synthase type 2 expression in asymptomatic, malaria-exposed children. 
  • Effects of cyclosporine on human B-cell lymphoma development in vivo. 
  • Effects of cysteamine therapy in nephropathic cystinosis. 
  • Effects of leukocyte depleted blood on renal reperfusion injury in a porcine model. 
  • Effects of pentoxifylline administration on blood viscosity and leukocyte cytoskeletal function in patients with intermittent claudication. 
  • Effects of photoperiod history on immune responses to intermediate day lengths in Siberian hamsters (Phodopus sungorus). 
  • Effects of treatment with pentoxifylline on the cardiovascular manifestations of group B streptococcal sepsis in the piglet. 
  • Elevated serum L-selectin levels and abnormal regulation of L-selectin expression on leukocytes in atopic dermatitis: soluble L-selectin levels indicate disease severity. 
  • Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone. 
  • EndothelinA receptor antagonist BSF-208075 causes immune modulation and neuroprotection after stroke in gerbils. 
  • Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. 
  • Enhanced bactericidal activity of phagocytes from patients with chronic granulomatous disease in the presence of sulphisoxazole. 
  • Enzymatic studies in the different types of normal and leukemic human white cells. 
  • Epigenetic Signatures of Cigarette Smoking. 
  • Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo. 
  • Examining Peripheral and Tumor Cellular Immunome in Patients With Cancer. 
  • Exfoliative cytopathologic studies in organ transplantation. 3. The cytologic profile of urine during acute renal allograft rejection. 
  • Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens. 
  • Extended storage of AS-1 and AS-3 leukoreduced red blood cells for 15 days after deglycerolization and resuspension in AS-3 using an automated closed system. 
  • Factors from saliva and oral bacteria, chemotactic for polymorphonuclear leukocytes: their possible role in gingival inflammation. 
  • False-positive calvarial uptake of indium-111 leukocytes in a patient with hyperostosis frontalis interna. 
  • Fate Mapping In Vivo to Distinguish Bona Fide Microglia Versus Recruited Monocyte-Derived Macrophages in Retinal Disease. 
  • Fecal leukocytes in stool specimens submitted for Clostridium difficile toxin assay. 
  • Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow. 
  • Freeze-fracture methods: preparation of complementary replicas for evaluating intracellular ice damage in ultrarapidly cooled specimens. 
  • Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration. 
  • Gamma (immune) interferon produced by leukocytes from a patients with a T cell proliferation disease. 
  • Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease. 
  • Generation of chemotactic activity by immune complexes carrying clustered or nonclustered C42 sites. 
  • Generation of full-length cDNA libraries enriched for differentially expressed genes. 
  • Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia. 
  • Genetic control of peripheral leukocyte response to endotoxin in mice. 
  • Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection. 
  • Graft donor selection based upon single locus (haplotype) analysis within families. 
  • Graft-versus-host disease as adoptive immunotherapy in patients with advanced hematologic neoplasms. 
  • Granulocyte-angiotensin system. Identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G. 
  • Guanine nucleotide regulatory proteins in receptor-mediated polyphosphoinositide hydrolysis in human leukocytes. 
  • Hematopoietic stem-cell transplantation in globoid-cell leukodystrophy. 
  • High-throughput cell focusing and separation via acoustofluidic tweezers. 
  • Host-Based Peripheral Blood Gene Expression Analysis for Diagnosis of Infectious Diseases. 
  • Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene. 
  • Human granulocyte collagenase. 
  • Human interleukin-2 and lymphoproliferative (T-helper cell) responses to soluble HLA class I antigens in vitro: I. Specificity for polymorphic domains. 
  • Human leukemia antigens: partial isolation and characterization. 
  • Human mononuclear leukocyte chemotaxis: a quantitative assay for humoral and cellular chemotactic factors. 
  • Human renal allograft rejection despite the absence of allogeneic passenger leukocytes. 
  • Human type 2 angiotensin II receptor gene: cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung. 
  • Humoral mediators of chemotaxis of mononuclear leukocytes. 
  • Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. 
  • I and i antigens on normal and leukemic leukocytes. 
  • ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. 
  • Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms. 
  • Imaging Cytometry of Human Leukocytes with Third Harmonic Generation Microscopy. 
  • Immune responses at the maternal-fetal interface. 
  • Immunological mechanisms of periodontal tissue destruction. 
  • Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes. 
  • In vitro assay of immunostimulatory activities of plasmid vectors. 
  • Increased interleukin-1β gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis. 
  • Increased numbers of total nucleated and CD34+ cells in blood group O cord blood: an analysis of neonatal innate factors in the Korean population. 
  • Increasing a microscope's effective field of view via overlapped imaging and machine learning. 
  • Infiltrating cell phenotypes and patterns associated with hepatic allograft rejection or acceptance. 
  • Inflammation and cardiopulmonary bypass. 
  • Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells. 
  • Inflammation and viral infection: chemotactic activity resulting from the interaction of antiviral antibody and complement with cells infected with herpes simplex virus. 
  • Inflammation does not predispose to bleeding in hemophilia. 
  • Inflammatory cell distribution within and along asthmatic airways. 
  • Influence of HIV-1 infection and cigarette smoking on leukocyte profile in homosexual men. 
  • Influences of inbreeding and genetics on telomere length in mice. 
  • Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis. 
  • Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021. 
  • Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis. 
  • Interactions of the complement system with endotoxic lipopolysaccharide. Generation of a factor chemotactic for polymorphonuclear leukocytes. 
  • Intercellular adhesion molecule-1 deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus. 
  • Interferon production in mixed cultures of murine leukocytes and syngeneic L1210 leukemia cells. 
  • Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder. 
  • Intravital fluorescence facilitates measurement of multiple physiologic functions and gene expression in tumors of live animals. 
  • Is chronic asthma associated with shorter leukocyte telomere length at midlife? 
  • Isolation of the JMH antigen on a novel phosphatidylinositol-linked human membrane protein. 
  • L-selectin and intercellular adhesion molecule-1 regulate the development of Concanavalin A-induced liver injury. 
  • L-selectin binds to P-selectin glycoprotein ligand-1 on leukocytes: interactions between the lectin, epidermal growth factor, and consensus repeat domains of the selectins determine ligand binding specificity. 
  • L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent of E- or P-selectin. 
  • L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1. 
  • L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro. 
  • L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites. 
  • Laboratory Accuracy Improvement in the UK NEQAS Leucocyte Immunophenotyping Immune Monitoring Program: An Eleven-Year Review via Longitudinal Mixed Effects Modeling. 
  • Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells. 
  • Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. 
  • Lectin and epidermal growth factor domains of P-selectin at physiologic density are the recognition unit for leukocyte binding. 
  • Letter: Role of reverse transcriptase. 
  • Leuko-polymersomes. 
  • Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study. 
  • Leukocyte activation by chemoattractant receptors: roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism. 
  • Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion. 
  • Leukocyte and Dried Blood Spot Arylsulfatase A Assay by Tandem Mass Spectrometry. 
  • Leukocyte chemoattractant peptides from the serpin heparin cofactor II. 
  • Leukocyte chemotactic activity from oral bacteria. 
  • Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. 
  • Leukocyte composition of human breast cancer. 
  • Leukocyte homing to synovium. 
  • Leukocyte inflammatory response in a rat urinary bladder regeneration model using porcine small intestinal submucosa scaffold. 
  • Leukocyte interactions with vascular endothelium. New insights into selectin-mediated attachment and rolling. 
  • Leukocyte migration is regulated by L-selectin endoproteolytic release. 
  • Leukocyte phenotypic changes in an in vitro model of ABO hemolytic transfusion reaction. 
  • Leukocyte rolling velocities and migration are optimized by cooperative L-selectin and intercellular adhesion molecule-1 functions. 
  • Leukocyte subpopulations in cerebrospinal fluid of normal rabbits. 
  • Leukocyte telomere dynamics and human hematopoietic stem cell kinetics during somatic growth. 
  • Leukocyte telomere length is associated with disability in older u.s. Population. 
  • Leukocyte telomere length, breast cancer risk in the offspring: the relations with father's age at birth. 
  • Leukocyte-capillary plugging and network resistance are increased in skeletal muscle of rats with streptozotocin-induced hyperglycemia. 
  • Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin. 
  • Leukocyte-reduced blood transfusions: perioperative indications, adverse effects, and cost analysis. 
  • Leukocytosis and hypoalbuminemia in mixed bipolar states: evidence for immune activation. 
  • Ligation of L-selectin through conserved regions within the lectin domain activates signal transduction pathways and integrin function in human, mouse, and rat leukocytes. 
  • Localization of a gene (CMT2A) for autosomal dominant Charcot-Marie-Tooth disease type 2 to chromosome 1p and evidence of genetic heterogeneity. 
  • Localization of heparin cofactor II in injured human skin: a potential role in wound healing. 
  • Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. 
  • Longer genotypically-estimated leukocyte telomere length is associated with increased meningioma risk. 
  • Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections. 
  • Low leucocyte ascorbic acid levels and corneal ulceration. 
  • Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. 
  • MEK1/2 inhibitors reverse acute vascular occlusion in mouse models of sickle cell disease. 
  • Macrophage proteinase and inflammation: the production of chemotactic activity from the fifth complement by macrophage proteinase. 
  • Male mice deficient in microsomal epoxide hydrolase are not susceptible to benzene-induced toxicity. 
  • Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors. 
  • Measurement of cellular proliferation within the vitreous during experimental proliferative vitreoretinopathy. 
  • Measurements from normal umbilical cord blood of four lysosomal enzymatic activities: alpha-L-iduronidase (Hurler), galactocerebrosidase (globoid cell leukodystrophy), arylsulfatase A (metachromatic leukodystrophy), arylsulfatase B (Maroteaux-Lamy). 
  • Mechanisms of inflammation and leukocyte activation. 
  • Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases. 
  • Mechanisms of regulating the respiratory burst in leukocytes. 
  • Mediators of pulmonary injury induced by inhalation of bacterial endotoxin. 
  • Methionine sulfoxide and the oxidative regulation of plasma proteinase inhibitors. 
  • Microvascular inflammation in renal allograft biopsies assessed by endothelial and leukocyte co-immunostain: a retrospective study on reproducibility and clinical/prognostic correlates. 
  • Minor RNA and other components of host origin intrinsic to avian leukosis virus particles. 
  • Model for leukocyte regulation by chemoattractant receptors: roles of a guanine nucleotide regulatory protein and polyphosphoinositide metabolism. 
  • Modeling deterministic effects in hematopoietic system caused by chronic exposure to ionizing radiation in large human cohorts. 
  • Molecular characterization of hypoxia-hypothermia-conditioned human endothelial cells and their interaction with human monocytes. 
  • Molecular mapping of functional domains of the leukocyte receptor for endothelium, LAM-1. 
  • Molecular mechanisms of leukocyte activation by chemoattractants. 
  • Monocytoid differentiation of freshly isolated human myeloid leukemia cells and HL-60 cells induced by the glutamine antagonist acivicin. 
  • Multiple loci are associated with white blood cell phenotypes. 
  • Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly. 
  • N-Formylmethionyl peptide receptors on equine leukocytes initiate secretion but not chemotaxis. 
  • Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection. 
  • Neutrophil accumulation and NET release contribute to thrombosis in HIT. 
  • Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. 
  • Noninvasive white blood cell quantification in umbilical cord blood collection bags with quantitative oblique back-illumination microscopy. 
  • Oncogenic base substitution mutations in circulating leukocytes of normal individuals. 
  • Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression. 
  • Optimism and telomere length among African American adults in the Jackson Heart Study. 
  • Overlapping roles for L-selectin and P-selectin in antigen-induced immune responses in the microvasculature. 
  • P- and L-selectin mediate distinct but overlapping functions in endotoxin-induced leukocyte-endothelial interactions in the rat mesenteric microcirculation. 
  • P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells. 
  • PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. 
  • PECAM-1: conflicts of interest in inflammation. 
  • Pathogenesis of pneumococcal pneumonia in cyclophosphamide-induced leukopenia in mice. 
  • Phase 1 study of the E-selectin inhibitor GMI 1070 in patients with sickle cell anemia. 
  • Phenotype and patterns of inflammatory cell infiltration associated with rejection or acceptance of rat liver allografts. 
  • Phospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3. 
  • Photoperiod affects the expression of sex and species differences in leukocyte number and leukocyte trafficking in congeneric hamsters. 
  • Placental/umbilical cord blood for unrelated-donor bone marrow reconstitution: relevance of nucleated red blood cells. 
  • Polymorphism and altered methylation of the lactoferrin gene in normal leukocytes, leukemic cells, and breast cancer. 
  • Postexposure immunoprophylaxis of primary isolates by an antibody to HIV receptor complex. 
  • Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I. 
  • Predicting glucose sensor behavior in blood using transport modeling: relative impacts of protein biofouling and cellular metabolic effects. 
  • Production of chemotactic activity by guinea pig immunoglobulins following activation of the C3 complement shunt pathway. 
  • Production of chemotactic factor and lymphotoxin by human leukocytes stimulated with Herpes simplex virus. 
  • Prospective evaluation of risk of protamine reactions in patients with NPH insulin-dependent diabetes. 
  • Protection of mice from Semliki Forest virus infection by lymphocytes treated with low levels of interferon. 
  • Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers. 
  • Pulmonary and pleural responses in Fischer 344 rats following short-term inhalation of a synthetic vitreous fiber. II. Pathobiologic responses. 
  • Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment. 
  • Quantitation of residual white cells in filtered blood components by polymerase chain reaction amplification of HLA DQ-A DNA. 
  • Rabbit anti-human leukocyte polyclonal antibody inhibits xenogeneic cell-mediated immune responses. 
  • Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function. 
  • Rapid freezing of whole blood or buffy coat samples for polymerase chain reaction and cell culture analysis: application to detection of human immunodeficiency virus in blood donor and recipient repositories. The Transfusion Safety Study Group. 
  • Reaction of a cobra venom factor with guinea pig complement and generation of an activity chemotactic for polymorphonuclear leukocytes. 
  • Reader technique as a source of variability in determining malaria parasite density by microscopy. 
  • Real-time observation of leukocyte-endothelium interactions in tissue-engineered blood vessel. 
  • Receptor class desensitization of leukocyte chemoattractant receptors. 
  • Receptor-mediated modulation of human monocyte, neutrophil, lymphocyte, and platelet function by phorbol diesters. 
  • Recommendations for the Use of WBC Growth Factors: American Society of Clinical Oncology Clinical Practice Guideline Update. 
  • Recovery of a human natural antibody against the noncollagenous-1 domain of type IV collagen using humanized models. 
  • Reduced beta-adrenergic receptor concentrations in ageing man. 
  • Reflectance confocal microscopy features of angioma serpiginosum. 
  • Regulation of L-selectin-mediated rolling through receptor dimerization. 
  • Regulation of beta-adrenergic receptors by steroid hormones. 
  • Regulation of leukocyte migration by L-selectin: mechanisms, domains and ligands. 
  • Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. 
  • Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1. 
  • Regulatory mechanisms of a chemoattractant receptor on leukocytes. 
  • Relation between non-uniform hemodynamics and sites of altered permeability and lesion growth at the rabbit aorto-celiac junction. 
  • Replication of type I herpes simplex virus in primary cultures of hairy cell leukemic leukocytes. 
  • Response of blood leukocytes to thrombin receptor peptides. 
  • Responses of baboons to prolonged hyperoxia: physiology and qualitative pathology. 
  • Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers. 
  • RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration. 
  • Role and regulation of sickle red cell interactions with other cells: ICAM-4 and other adhesion receptors. 
  • Role of adhesion molecules in the pathogenesis of rheumatoid arthritis. 
  • Role of granulocyte collagenase in collagen degradation. 
  • Role of guanine nucleotide regulatory protein in polyphosphoinositide degradation and activation of phagocytic leukocytes by chemoattractants. 
  • Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. 
  • Role of receptor mechanisms in the adaptive response to habitual exercise. 
  • Role of vascular leukocytes in ovarian cancer neovascularization. 
  • Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin. 
  • Rous sarcoma virus-induced tumours in mice. II. Contribution of H-2 and non-H-2 alloantigen barriers to tumour immunogenicity in vivo. 
  • SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model. 
  • Scavenger receptor-A-targeted leukocyte depletion inhibits peritoneal ovarian tumor progression. 
  • Sequential contribution of L- and P-selectin to leukocyte rolling in vivo. 
  • Serial in vivo observations of cerebral vasculature after treatment with a large single fraction of radiation. 
  • Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune function. 
  • Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms. 
  • Social factors and leukocyte DNA methylation of repetitive sequences: the multi-ethnic study of atherosclerosis. 
  • Social status alters immune regulation and response to infection in macaques. 
  • Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. 
  • Some fixation reagents reduce or abolish the detectability of Ia-antigen and HLA-DR on cells. 
  • Sources of variability in determining malaria parasite density by microscopy. 
  • Spatiotemporal programming of a simple inflammatory process. 
  • Studies of the multifaceted mast cell response to bacteria. 
  • Synergism between platelets and leukocytes in inducing endothelial cell apoptosis in the cold ischemic rat liver: a Kupffer cell-mediated injury. 
  • Telomerase activity in normal leukocytes and in hematologic malignancies. 
  • Telomere Attrition in Childhood Cancer Survivors. 
  • Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus 
  • Telomeres and the natural lifespan limit in humans. 
  • Tempering allorecognition to induce transplant tolerance with chemically modified apoptotic donor cells. 
  • Tensor diffusion imaging in B12 leukoencephalopathy. 
  • The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B. 
  • The cell and molecular basis of leukocyte common antigen (CD45)-triggered, lymphocyte function-associated antigen-1-/intercellular adhesion molecule-1-dependent, leukocyte adhesion. 
  • The clinical value of qualitative peripheral blood leukocyte changes. 
  • The cutaneous lymphocyte antigen is an essential component of the L-selectin ligand induced on human vascular endothelial cells. 
  • The cutaneous reverse Arthus reaction requires intercellular adhesion molecule 1 and L-selectin expression. 
  • The distribution of intimal white blood cells in the normal rabbit aorta. 
  • The effect of temperature variation in vitro on platelet-leukocyte interactions and individual prothrombotic potential. 
  • The effects of smoking on levels of endothelial progenitor cells and microparticles in the blood of healthy volunteers. 
  • The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators. 
  • The gut microbiota is associated with immune cell dynamics in humans. 
  • The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions. 
  • The immunological axis in heart failure: importance of the leukocyte differential. 
  • The light microscopic demonstration of hydroperoxidase-positive Phi bodies and rods in leukocytes in acute myeloid leukemia. 
  • The relationship of complement consumption to immune fever. 
  • The role of adhesion molecules in human leukocyte attachment to porcine vascular endothelium: implications for xenotransplantation. 
  • The role of dendritic cell precursors in tumour vasculogenesis. 
  • The role of neutral proteinase and cathepsin D in turpentine-induced inflammation. 
  • The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes. 
  • The role of the immune response in the development of periodontal disease. 
  • The roles of L-selectin, beta 7 integrins, and P-selectin in leukocyte rolling and adhesion in high endothelial venules of Peyer's patches. 
  • The selectins: vascular adhesion molecules. 
  • The suppressive effect of a synthetic retroviral peptide on the human IFN gamma production is abrogated by the combined stimulation with IL-1 and IL-2. 
  • The use of in vitro technics to study drug-induced pancytopenia. 
  • Therapeutic white blood cell and platelet depletions using the spectra OPTIA system continuous mononuclear cell protocol. 
  • Tissue antigens of man and chimpanzees; their role in xenografting. 
  • Transductional mechanisms of chemoattractant receptors on leukocytes. 
  • Tumor necrosis factor, natural killer activity and other measures of immune function and inflammation in elderly men with heart failure. 
  • Tunable leuko-polymersomes that adhere specifically to inflammatory markers. 
  • Ultrastructural studies of unstable angina in living man. 
  • Ultrastructural study of the corneal epithelium in the recurrent erosion syndrome. 
  • Ultrastructure and function of the fractalkine mucin domain in CX(3)C chemokine domain presentation. 
  • Unaltered graft survival and intragraft lymphocytes infiltration in the cardiac allograft of Cxcr3-/- mouse recipients. 
  • Updates and Critical Evaluation on Novel Biomarkers for the Malignant Progression of Intraductal Papillary Mucinous Neoplasms of the Pancreas. 
  • Variability in B cell maturation and differentiation in X-linked agammaglobulinemia. 
  • Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 
  • Vascular leukocytes contribute to tumor vascularization. 
  • Vascular leukocytes: a population with angiogenic and immunossuppressive properties highly represented in ovarian cancer. 
  • Virulence factors identified by Cryptococcus neoformans mutant screen differentially modulate lung immune responses and brain dissemination. 
  • Visualization of carbohydrate-binding molecules expressed by myelomono- and erythropoietic cells derived from human bone marrow: an immunoenzymatic double-staining study. 
  • What happens in lead poisoning? 
  • White Blood Cell Count and Major Adverse Cardiovascular Events After Percutaneous Coronary Intervention in the Contemporary Era: Insights From the PARIS Study (Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients Registry). 
  • Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality. 
  • Xenotransplantation of baboon bone marrow cells: a historical review of the protocols as a possible treatment modality for HIV/AIDS. 
  • [Comparative study of polynuclear and mononuclear cell metabolism in man]. 
  • [Leukocyte levels of adenosine phosphates]. 
  • [Metabolic changes in human leukocytes during phagocytosis]. 
  • [THE ENZYMES OF THE LEUKOCYTE]. 
  • β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway. 
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  Keywords of People

  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor Emeritus of Pediatrics, in the School of Medicine, Pediatrics, Allergy and Immunology
  • Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology
  • Lagoo, Anand Shreeram, Professor of Pathology, Pathology
  • McClain, Micah Thomas, Associate Professor of Medicine, Medicine, Infectious Diseases
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Zennadi, Rahima, Associate Professor in Medicine, Pathology