Leydig Cells

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  Subject Areas on Research

  • Adrenocorticotropic hormone directly stimulates testosterone production by the fetal and neonatal mouse testis. 
  • Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis. 
  • Mixed signals: development of the testis. 
  • Notch signaling maintains Leydig progenitor cells in the mouse testis. 
  • Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. 
  • One tissue, two fates: molecular genetic events that underlie testis versus ovary development. 
  • Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad. 
  • Regulation of the macrophage population in postnatal rat testis. 
  • Signaling at the crossroads of gonad development. 
  • Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis. 
  • Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling. 
  • The metabolism of luteinizing hormone. Plasma clearance, urinary excretion, and tissue uptake. 
  • The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis. 
  • Two distinct origins for Leydig cell progenitors in the fetal testis.