Gonadotropin-Releasing Hormone
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Subject Areas on Research
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A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH.
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A mathematical model quantifying GnRH-induced LH secretion from gonadotropes.
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A phase III extension trial with a 1-arm crossover from leuprolide to degarelix: comparison of gonadotropin-releasing hormone agonist and antagonist effect on prostate cancer.
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A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men.
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Acute and subacute effects of naturally occurring estrogens on luteinizing hormone secretion in the ovariectomized rat: Part 1.
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Acute and subacute effects of naturally occurring estrogens on luteinizing hormone secretion in the ovariectomized rat: Part 2.
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Additional analysis of the secondary end point of biochemical recurrence rate in a phase 3 trial (CS21) comparing degarelix 80 mg versus leuprolide in prostate cancer patients segmented by baseline characteristics.
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Adjunctive leuprolide therapy does not improve cycle fecundity in controlled ovarian hyperstimulation and intrauterine insemination of subfertile women.
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Alterations in luteal phase progesterone and estradiol production after leuprolide acetate therapy before ovarian stimulation for in vitro fertilization.
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Amenorrhea: observations based on the analysis of luteinizing hormone-releasing hormone testing.
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Androgen deprivation therapy and estrogen deficiency induced adverse effects in the treatment of prostate cancer.
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Androgen-deprivation therapy and diabetes control among diabetic men with prostate cancer.
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Androgen-deprivation therapy and metabolic syndrome in men with prostate cancer.
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Anogenital distance at birth as a predictor of volume of the sexually dimorphic nucleus of the preoptic area of the hypothalamus and pituitary responsiveness in castrated adult rats.
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Are Small Reimbursement Changes Enough to Change Cancer Care? Reimbursement Variation in Prostate Cancer Treatment.
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Basic fibroblast growth factor regulates the conversion of pro-luteinizing hormone-releasing hormone (Pro-LHRH) to LHRH in immortalized hypothalamic neurons.
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Challenges to our understanding of endometriosis pain.
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Changes in alkaline phosphatase levels in patients with prostate cancer receiving degarelix or leuprolide: results from a 12-month, comparative, phase III study.
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Clinical characteristics of ovulation induction with human menopausal gonadotropins with and without leuprolide acetate in polycystic ovary syndrome.
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Clinical decision making regarding leiomyomata: what we need in the next millenium.
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Combination hormonal therapy: a reassessment within advanced prostate cancer.
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Combined antibody-high-performance liquid chromatography approach to assess prohormone processing.
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Combined impact of the number of pre-ovulatory oocytes and cryopreservation on IVF outcome.
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Construction and analysis of protein-protein interaction networks based on proteomics data of prostate cancer.
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Contemporary hormonal management of advanced prostate cancer.
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Cycle day, estrogen level, and lead follicle size: analysis of 27,790 in vitro fertilization cycles to determine optimal start criteria for gonadotropin-releasing hormone antagonist.
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Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice.
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Detectable prostate-specific antigen Nadir during androgen-deprivation therapy predicts adverse prostate cancer-specific outcomes: results from the SEARCH database.
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Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans with prostate cancer.
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Diabetes and cardiovascular disease during androgen deprivation therapy: observational study of veterans with prostate cancer.
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Differential expression of gamma-aminobutyric acid receptors in immortalized luteinizing hormone-releasing hormone neurons.
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Differential secretion of proLHRH fragments in response to [K+], prostaglandin E2 and C kinase activation.
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Dose-response characteristics of neonatal exposure to genistein on pituitary responsiveness to gonadotropin releasing hormone and volume of the sexually dimorphic nucleus of the preoptic area (SDN-POA) in postpubertal castrated female rats.
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Early prostate cancer: the national results of radiation treatment from the Patterns of Care and Radiation Therapy Oncology Group studies with prospects for improvement with conformal radiation and adjuvant androgen deprivation.
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Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy.
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Effect of neonatal diethylstilbestrol exposure on luteinizing hormone secretion following ketamine anesthesia and gonadotropin-releasing hormone in castrated postpubertal rats.
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Effect of neonatal diethylstilbestrol exposure on volume of the sexually dimorphic nucleus of the preoptic area of the hypothalamus and pituitary responsiveness to gonadotropin-releasing hormone in female rats of known anogenital distance at birth.
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Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice.
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Effects of charcoal-extracted follicular fluid on reproductive function in postpartum cows.
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Effects of insulin-like growth factors I and II and insulin on the immortalized hypothalamic GTI-7 cell line.
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Effects of phytoestrogens on GnRH-induced luteinizing hormone secretion in ovariectomized rats.
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Effects of prenatal treatment with antiandrogens on luteinizing hormone secretion and sex steroid concentrations in adult spotted hyenas, Crocuta crocuta.
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Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation.
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Endocrine therapy in metastatic breast cancer.
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Endometrial receptivities after leuprolide suppression and gonadotropin stimulation: histology, steroid receptor concentrations, and implantation rates.
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Endoscopic management of leiomyomata.
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Expression of candidate pro-GnRH processing enzymes in rat hypothalamus and an immortalized hypothalamic neuronal cell line.
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External beam radiation therapy for clinically localized prostate cancer: when and how we optimize with concurrent hormonal deprivation.
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FSH suppression and tumour control in patients with prostate cancer during androgen deprivation with a GnRH agonist or antagonist.
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Follicular atresia associated with concurrent initiation of gonadotropin-releasing hormone agonist and follicle-stimulating hormone for oocyte recruitment.
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Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency.
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Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome.
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Gonadotropin releasing hormone stimulates calmodulin redistribution in rat pituitary.
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Gonadotropin-releasing hormone agonist overuse: urologists' response to reimbursement and characteristics associated with persistent overuse.
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Gonadotropin-releasing hormone agonists and the risks of type 2 diabetes and cardiovascular disease in men with prostate cancer.
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Gonadotropin-releasing hormone analog cotreatment for preservation of ovarian function during gonadotoxic chemotherapy: a systematic review and meta-analysis.
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Gonadotropin-releasing hormone neuronal cell lines.
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High Peak Estradiol Predicts Higher Miscarriage and Lower Live Birth Rates in High Responders Triggered with a GnRH Agonist in IVF/ICSI Cycles.
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High Peak Estradiol/Mature Oocyte Ratio Predicts Lower Clinical Pregnancy, Ongoing Pregnancy, and Live Birth Rates in GnRH Antagonist Intracytoplasmic Sperm Injection Cycles.
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Hormonal characteristics of free-ranging female lions (Panthera leo) of the Serengeti Plains and Ngorongoro Crater.
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Hormone naïve prostate cancer: predicting and maximizing response intervals.
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Hydrolysis by somatic angiotensin-I converting enzyme of basic dipeptides from a cholecystokinin/gastrin and a LH-RH peptide extended at the C-terminus with gly-Arg/Lys-arg, but not from diarginyl insulin.
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Hypothalamic and pituitary function in hypogonadotropic hypogonadism.
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Hypothalamic astrocytes respond to transforming growth factor-alpha with the secretion of neuroactive substances that stimulate the release of luteinizing hormone-releasing hormone.
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Immortalized hypothalamic gonadotropin-releasing hormone neurons.
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Immortalized hypothalamic luteinizing hormone-releasing hormone (LHRH) neurons: a new tool for dissecting the molecular and cellular basis of LHRH physiology.
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Impact of leuprolide acetate on the response to follicular stimulation for in vitro fertilization in patients with normal basal gonadotropin levels.
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Implantation and pregnancy rates in relation to oestradiol and progesterone profiles in cycles with and without the use of gonadotrophin-releasing hormone agonist suppression.
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In-vitro fertilization and embryo transfer in patients with endometriosis: impact of a gonadotrophin releasing hormone agonist.
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Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists.
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Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons.
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Lack of effects from 2000-Hz magnetic fields on mammary adenocarcinoma and reproductive hormones in rats
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Late ovarian hyperstimulation syndrome after controlled ovarian stimulation in a woman with systemic lupus erythematosus and lupus nephritis.
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Luteal supplementation in in vitro fertilization: more questions than answers.
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Management of metastatic prostatic cancer.
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Mathematical modeling of perifusion cell culture experiments on GnRH signaling.
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Mechanism of action of hypothalamic hormones in the anterior pituitary gland and specific modulation of their activity by sex steroids and thyroid hormones.
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Metabolism of pro-luteinizing hormone-releasing hormone in immortalized hypothalamic neurons.
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Microcephaly, hypergonadotropic hypogonadism, short stature, and minor anomalies: a new syndrome.
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Mild/minimal stimulation for in vitro fertilization: an old idea that needs to be revisited.
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Minimal ovarian hyperstimulation for in vitro fertilization using sequential clomiphene citrate and gonadotropin with or without the addition of a gonadotropin-releasing hormone antagonist.
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Morphological characterization of immortalized hypothalamic neurons synthesizing luteinizing hormone-releasing hormone.
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NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.
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Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons.
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Neuroendocrine control of follicle-stimulating hormone (FSH) secretion: II. Is follistatin-induced suppression of FSH secretion mediated via changes in activin availability and does it involve changes in gonadotropin-releasing hormone secretion?
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New data, new paradigms for treating prostate cancer patients--VI: novel hormonal therapy approaches.
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Orchidectomy induces temporal and regional changes in the synthesis and processing of the LHRH prohormone in the rat brain.
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Ovarian hyperstimulation in polycystic ovary syndrome during therapy with leuprolide acetate.
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Ovarian preservation by GnRH agonists during chemotherapy: a meta-analysis.
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Ovarian stimulation for in vitro fertilization using pure follicle-stimulating hormone with and without gonadotropin-releasing hormone agonist in high-responder patients.
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Overview consensus statement. Newer approaches to androgen deprivation therapy in prostate cancer.
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Pathology and pathophysiology of uterine smooth-muscle tumors.
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Performance of cryopreserved pre-embryos obtained in in vitro fertilization cycles with or without a gonadotropin-releasing hormone agonist.
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Polymer-delivered subcutaneous leuprolide acetate formulations achieve and maintain castrate concentrations of testosterone in four open-label studies in patients with advanced prostate cancer.
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Predictors and implications of estradiol rise after gonadotropin-releasing hormone antagonist initiation during in vitro fertilization cycles.
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Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse.
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Pro-GnRH processing.
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Processing of the luteinizing hormone-releasing hormone precursor in the preoptic area and hypothalamus of the rat.
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Progesterone levels on the day of human chorionic gonadotropin administration in cycles with gonadotropin-releasing hormone agonist suppression are not predictive of pregnancy outcome.
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Progesterone levels on the day of human chorionic gonadotropin do not predict pregnancy outcome from the transfer of fresh or cryopreserved embryos from the same cohort.
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Prostate cancer: diagnosis, treatment, and experience at one tertiary-care military medical center, 1989 and 1994.
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Prostate cancer: making the switch from LHRH antagonist to LHRH agonist.
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Rapid behavioral and genomic responses to social opportunity.
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Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons.
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Regulation of gonadotropin-releasing hormone secretion by cannabinoids.
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Relative effectiveness and cost-effectiveness of methods of androgen suppression in the treatment of advanced prostate cancer.
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Role of aromatase in endometrial disease.
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Role of gonadotropin-releasing hormone pulse frequency in differential regulation of gonadotropins in the gilt.
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Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysis.
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Stimulation protocols for patients with "atypical response".
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Suppression and flare regimens of gonadotropin-releasing hormone agonist. Use in women with different basal gonadotropin values in an in vitro fertilization program.
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Suppression of male-specific cytochrome P450 2c and its mRNA by 3,4,5,3',4',5'-hexachlorobiphenyl in rat liver is not causally related to changes in serum testosterone.
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Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma.
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Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
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Targeting the androgen receptor--theory and practice.
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Testosterone administration suppresses adiponectin levels in men.
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Testosterone rapidly increases neural reactivity to threat in healthy men: a novel two-step pharmacological challenge paradigm.
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Testosterone selectively influences protein kinase-C-coupled secretion of proluteinizing hormone-releasing hormone-derived peptides.
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The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-alpha.
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The effect of leuprolide acetate on ovulation induction with human menopausal gonadotropins in polycystic ovary syndrome.
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The effect of neonatal exposure to DES and o,p'-DDT on pituitary responsiveness to GnRH in adult castrated rats.
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The effect of neonatal exposure to diethylstilbestrol, coumestrol, and beta-sitosterol on pituitary responsiveness and sexually dimorphic nucleus volume in the castrated adult rat.
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The effect of neonatal exposure to diethylstilbestrol, genistein, and zearalenone on pituitary responsiveness and sexually dimorphic nucleus volume in the castrated adult rat.
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The effect of prenatal exposure to the phytoestrogen genistein on sexual differentiation in rats.
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The luteal phase in polycystic ovary syndrome during ovulation induction with human menopausal gonadotropin with and without leuprolide acetate.
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The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus.
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The role of primary androgen deprivation therapy in localized prostate cancer.
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Transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH): effect of repeated administration.
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Transdermal iontophoretic peptide delivery: in vitro and in vivo studies with luteinizing hormone releasing hormone.
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Transfer of cryopreserved-thawed pre-embryos in a cycle using exogenous steroids without prior gonadotrophin-releasing hormone agonist suppression yields favourable pregnancy results.
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Twenty years of controversy surrounding combined androgen blockade for advanced prostate cancer.
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Twenty-five year evolution of medical hormonal therapy for prostate cancer.
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Utility of LHRH antagonists for advanced prostate cancer.
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Value of suppression with a gonadotropin-releasing hormone agonist prior to gonadotropin stimulation for in vitro fertilization.
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alpha(1)-adrenergic receptors mediate LH-releasing hormone secretion through phospholipases C and A(2) in immortalized hypothalamic neurons.
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p53 protein expression status and recurrence in men treated with radiation and androgen suppression therapy for higher-risk prostate cancer: a prospective phase II Cancer and Leukemia Group B Study (CALGB 9682).