Lidocaine

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  Subject Areas on Research

  • A Method for Cranial Nerve XI Silencing During Surgery of the Foramen Magnum Region: Technical Case Report. 
  • A comparison of rocuronium and lidocaine for the prevention of postoperative myalgia after succinylcholine administration. 
  • A double-masked randomized trial of postoperative local anesthetic for pain control in pediatric strabismus surgery. 
  • A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias. 
  • A novel paraplegia model in awake behaving macaques. 
  • A prospective blinded trial of warm and cold lidocaine for intradermal injection. 
  • A quantitative description of QX222 blockade of sodium channels in squid axons. 
  • Addition of epinephrine to epidural bupivacaine infusions following initiation of labor analgesia with epidural fentanyl. 
  • Adult template circumcision: a prospective, randomized, patient-blinded, comparative study evaluating the safety and efficacy of a novel circumcision device. 
  • Alcohol spray vs. intradermal lidocaine before intravenous cannulation. 
  • Analgesia in the surgical intensive care unit. 
  • Analysis of the action of lidocaine on insect sodium channels. 
  • Anesthetic induction with fentanyl and intravenous lidocaine for coronary artery surgery. 
  • Anesthetic management of a patient having a carcinoid syndrome. 
  • Antiarrhythmic drug action. Blockade of the inward sodium current. 
  • Antiarrhythmic drug action: selective depression of hypoxic cardiac cells. 
  • Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction. 
  • Autonomic Modulation for the Treatment of Ventricular Arrhythmias: Therapeutic Use of Percutaneous Stellate Ganglion Blocks. 
  • Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells. 
  • Blockade of cardiac sodium channels by amitriptyline and diphenylhydantoin. Evidence for two use-dependent binding sites. 
  • Blockade of cardiac sodium channels by lidocaine. Single-channel analysis. 
  • Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs. 
  • Blockade of rabbit atrial sodium channels by lidocaine. Characterization of continuous and frequency-dependent blocking. 
  • Brain-stem anesthesia. An unusual complication of stellate ganglion block. 
  • Breast lidocaine priming for improved mastectomy survival. 
  • Brief report: a randomized controlled trial of Synera versus lidocaine for epidural needle insertion in labouring parturients. 
  • Cardiac function after restoration of flow in acute coronary occlusion. 
  • Cardiac instability amplified by use-dependent Na channel blockade. 
  • Closed Continuous Irrigation With Lidocaine and Immediate Mobilization for Treatment of Pyogenic Tenosynovitis. 
  • Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions. 
  • Combination of Lidocaine and IL-1Ra Is Effective at Reducing Degradation of Porcine Cartilage Explants. 
  • Combined general-epidural anesthesia decreases the desflurane requirement for equivalent A-line ARX index in colorectal surgery. 
  • Comparative effects of lidocaine and procainamide on acutely impaired hemodynamics. 
  • Comparative pharmacodynamics of intravenous lidocaine in patients with acute and chronic ventricular arrhythmias. 
  • Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: effects of cocaine and related drugs. 
  • Double-blind randomized comparison of intravenous tocainide versus lidocaine in the treatment of chronic ventricular arrhythmias. 
  • Effect of age and gender on the activity of human hepatic CYP3A. 
  • Effect of epidural lidocaine on spinal cord blood flow. 
  • Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial. 
  • Effect of lidocaine gel anesthesia on endophthalmitis rates following intravitreal injection. 
  • Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. 
  • Effective local anesthesia for onabotulinumtoxin A injections to treat hyperhidrosis associated with traumatic amputation. 
  • Effective spread and timecourse of neural inactivation caused by lidocaine injection in monkey cerebral cortex. 
  • Electromyographic assessment of ulnar nerve motor block induced by lidocaine. 
  • Elevated lidocaine serum concentration after subcutaneous lidocaine administration using a needle-free device in pediatric patients. 
  • Elevated lidocaine serum levels following the use of a needle free device in healthy adult volunteers. 
  • Endotracheal lidocaine administration via an esophageal combitube. 
  • Evaluation of a new cutaneous topical anesthesia preparation. 
  • Exploring the role of pH in modulating the effects of lidocaine in virtual ischemic tissue. 
  • Factors affecting pain scores during female urethral catheterization. 
  • Grand mal seizure during cardiopulmonary bypass: probable lidocaine toxicity. 
  • How central is central poststroke pain? The role of afferent input in poststroke neuropathic pain: a prospective, open-label pilot study. 
  • Immediate thalamic sensory plasticity depends on corticothalamic feedback. 
  • Impact of Sodium Bicarbonate-Buffered Lidocaine on Patient Pain During Image-Guided Breast Biopsy. 
  • Impact of intravenous lidocaine infusion on postoperative analgesia and recovery from surgery: a systematic review of randomized controlled trials. 
  • In vitro effects of lidocaine on anaerobic respiratory pathogens and strains of Hemophilus influenzae. 
  • In vitro evaluation of diffusion of lidocaine and alkalinized lidocaine through the polyurethane membrane of the endotracheal tube. 
  • In vivo diffusion-weighted magnetic resonance microscopy of rat spinal cord: effect of ischemia and intrathecal hyperbaric 5% lidocaine. 
  • Induction of immediate spatiotemporal changes in thalamic networks by peripheral block of ascending cutaneous information. 
  • Inferior oblique overaction/contracture following retrobulbar anesthesia for cataract extraction with a positive Bielschowsky Head Tilt test to the contralateral shoulder. A report of one case. 
  • Influence of buffers on dV/dtmax recovery kinetics with lidocaine in myocardium. 
  • Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade. 
  • Intracameral anesthesia: in vitro iris and corneal uptake and washout of 1% lidocaine hydrochloride. 
  • Intrathecal sufentanil for extracorporeal shock wave lithotripsy provides earlier discharge of the outpatient than intrathecal lidocaine. 
  • Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial. 
  • Intravenous Lidocaine and Postoperative Cognition: Reply. 
  • Intravenous Migraine Treatment in Children and Adolescents. 
  • Ischemia contributes to adverse effects of cocaine on brain development: suppression of ornithine decarboxylase activity in neonatal rat. 
  • Kinetics of interaction of the lidocaine metabolite glycylxylidide with the cardiac sodium channel. Additive blockade with lidocaine. 
  • Laser Doppler flowmetry: a clinical test of pulpal vitality. 
  • Lidocaine Infusion as an Adjunct to Narcotics in Trauma Patients with Rib Fractures-A Pilot Study. 
  • Lidocaine blockade of continuously and transiently accessible sites in cardiac sodium channels. 
  • Lidocaine lollipop as single-agent anesthesia in upper GI endoscopy. 
  • Lidocaine lollipop for awake fiberoptic bronchoscopy. 
  • Lidocaine patch for acute pain management: a meta-analysis of prospective controlled trials. 
  • Lidocaine patch for postoperative analgesia after radical retropubic prostatectomy. 
  • Lidocaine-Prilocaine Cream Compared With Injected Lidocaine for Vulvar Biopsy: A Randomized Controlled Trial. 
  • Ligand binding to transiently accessible sites: mechanisms for varying apparent binding rates. 
  • Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium. 
  • Local anesthetics, neuraxial anesthesia, and the Brugada syndrome. 
  • Marked QRS complex abnormalities and sodium channel blockade by propoxyphene reversed with lidocaine. 
  • Modulating intraventricular conduction through competition of two class 1 antiarrhythmic agents: experience with ethacizin and lidocaine in canine heart. 
  • Multicenter randomized trial and a systematic overview of lidocaine in acute myocardial infarction. 
  • Mutations in the transmembrane helix S6 of domain IV confer cockroach sodium channel resistance to sodium channel blocker insecticides and local anesthetics. 
  • Neural origin of evoked potentials during thalamic deep brain stimulation. 
  • Neuroanesthesia Guidelines for Optimizing Transcranial Motor Evoked Potential Neuromonitoring During Deformity and Complex Spinal Surgery: A Delphi Consensus Study. 
  • New technique for capillary electrophoresis directly coupled with end-column electrochemiluminescence detection. 
  • Pain perception with cervical tenaculum placement during intrauterine device insertion: a randomised controlled trial. 
  • Pharmacokinetic studies: their role in determining therapeutic efficacy of agents designed to prevent sudden death. 
  • Pharmacological interventions to decompression sickness in rats: comparison of five agents. 
  • Phasic ion channel blockade. A kinetic model and parameter estimation procedure. 
  • Population pharmacokinetics of lidocaine administered during and after cardiac surgery. 
  • Posterior lingual lidocaine: a novel method to improve tolerance in upper gastrointestinal endoscopy. 
  • Preventing pain during office biopsy of the prostate: a single center, prospective, double-blind, 3-arm, parallel group, randomized clinical trial. 
  • Prophylactic lidocaine use in acute myocardial infarction: incidence and outcomes from two international trials. The GUSTO-I and GUSTO-IIb Investigators. 
  • Randomized Controlled Trial to Assess the Impact of High Concentration Intraurethral Lidocaine on Urodynamic Voiding Parameters. 
  • Randomized Controlled Trial to Assess the Impact of Intraurethral Lidocaine on Urodynamic Voiding Parameters. 
  • Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery. 
  • Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe). 
  • Re: Inferior oblique overaction/contracture following retrobulbar anesthesia for cataract extraction with a positive Bielschowsky Head Tilt Test to the contralateral shoulder. A report of one case. 
  • Recurrent interactions between the input and output of a songbird cortico-basal ganglia pathway are implicated in vocal sequence variability. 
  • Relationship between structure and sodium channel blockade by lidocaine and its amino-alkyl derivatives. 
  • Relief of blood-induced arterial vasospasm by pharmacologic solutions. 
  • Response to "Intraurethral Lidocaine Use During Urodynamic Testing Deserves Further Study". 
  • Reversible inactivation of macaque dorsomedial frontal cortex: effects on saccades and fixations. 
  • Reversible inactivation of macaque frontal eye field. 
  • Role of pudendal afferents in voiding efficiency in the rat 
  • Sensory blockade of smoking satisfaction. 
  • Short-capillary electrophoresis with electrochemiluminescence detection using porous etched joint for fast analysis of lidocaine and ofloxacin. 
  • Small-dose intrathecal lidocaine versus ropivacaine for anorectal surgery in an ambulatory setting. 
  • Subtle desaturation and perioperative methemoglobinemia. The need for continued vigilance. 
  • Synaptic basis for developmental plasticity in a birdsong nucleus. 
  • The effects of intraocular lidocaine on the corneal endothelium. 
  • The functional anatomy of limbic status epilepticus in the rat. II. The effects of focal deactivation. 
  • The influence of pH on th electrophysiological effects of lidocaine in guinea pig ventricular myocardium. 
  • The interaction effect of perioperative cotreatment with dextromethorphan and intravenous lidocaine on pain relief and recovery of bowel function after laparoscopic cholecystectomy. 
  • The predictive value of donor liver biopsies for the development of primary nonfunction after orthotopic liver transplantation. 
  • The use of topical anesthesia during intravenous catheter insertion in adults: a comparison of pain scores using LMX-4 versus placebo. 
  • Theoretical characterization of ion channel blockade. Competitive binding to periodically accessible receptors. 
  • Tocainide kinetics in congestive heart failure. 
  • Topical anesthesia with EMLA reduces pain during endomyocardial biopsy: a randomized trial. 
  • Treatment and prevention of postherpetic neuralgia. 
  • Treatment of decompression illness and latrogenic gas embolism. 
  • Treatment of dopplerable nummular headache with minimally invasive arterectomy under local anesthesia. 
  • Trends Over Time in Drug Administration During Adult In-Hospital Cardiac Arrest. 
  • Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability. 
  • Use of a simple forearm tourniquet as an adjunct to an intravenous regional block. 
  • Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat. 
  • Use of percutaneously inserted venous catheters in coronary care units. 
  • Use of targeted transversus abdominus plane blocks in pediatric patients with anterior cutaneous nerve entrapment syndrome. 
  • Vasodilator action of prostaglandin E1 on microcirculation of rat cremaster muscle. 
  • [The combined effect of 2 first-line anti-arrhythmia drugs on the conduction velocity of myocardial stimulation]. 
  • pH dependence of kinetics and steady-state block of cardiac sodium channels by lidocaine. 
  • pKa does not predict pH potentiation of sodium channel blockade by lidocaine and W6211 in guinea pig ventricular myocardium. 
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  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Routh, Jonathan Charles, Paul H. Sherman, M.D. Distinguished Associate Professor of Surgery, Pediatrics
  • Starmer, Charles Franklin, Professor Emeritus of Computer Science, Computer Science