-
Subject Areas on Research
-
"Low-level" carbon monoxide administration may carry risk.
-
25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.
-
A behavioural characterization of neonatal infection-facilitated memory impairment in adult rats.
-
A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase.
-
A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.
-
A mouse macrophage lipidome.
-
A noncanonical function of cGAMP in inflammasome priming and activation.
-
A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells.
-
A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury.
-
A selective inhibitor of cyclooxygenase-2 reverses endotoxin-induced pyretic responses in non-human primates.
-
A subset of human monocyte-derived dendritic cells expresses high levels of interleukin-12 in response to combined CD40 ligand and interferon-gamma treatment.
-
A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis.
-
A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression.
-
AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia.
-
Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo.
-
Abnormal production of interleukin-1 by microglia from trisomy 16 mice.
-
Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats.
-
Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma.
-
Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice.
-
Activation of Nrf2 Pathway Contributes to Neuroprotection by the Dietary Flavonoid Tiliroside.
-
Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after lipopolysaccharide-induced lung inflammation.
-
Activation of complement by endotoxin.
-
Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth.
-
Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation.
-
Active immunotherapy for TNF-mediated inflammation using self-assembled peptide nanofibers.
-
Agathisflavone isolated from Anacardium occidentale suppresses SIRT1-mediated neuroinflammation in BV2 microglia and neurotoxicity in APPSwe-transfected SH-SY5Y cells.
-
Aging and dietary modulation of elastase and interleukin-1 beta secretion.
-
Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
-
Allogeneic splenocyte transfer and lipopolysaccharide inhalations induce differential T cell expansion and lung injury: a novel model of pulmonary graft-versus-host disease.
-
Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide.
-
Alpha 2 macroglobulin-proteinase complexes stimulate prostaglandin E2 synthesis by peritoneal macrophages.
-
Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage.
-
Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation.
-
Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype.
-
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.
-
Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury.
-
Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells.
-
Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia.
-
Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia Through Nrf2-Dependent Mechanisms.
-
Antisense inhibition of group II phospholipase A2 expression blocks the production of prostaglandin E2 by P388D1 cells.
-
Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport.
-
Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response.
-
Apolipoprotein E suppresses glial cell secretion of TNF alpha.
-
Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis.
-
Application of lipoarabinomannan antigen in tuberculosis diagnostics: current evidence.
-
Aspirin inhibits tumor necrosis factoralpha gene expression in murine tissue macrophages.
-
Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.
-
Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha.
-
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms.
-
Bacterial lipopolysaccharide induces uncoupling protein-2 expression in hepatocytes by a tumor necrosis factor-alpha-dependent mechanism.
-
Bacterial lipopolysaccharides and mycoplasmal lipoglycans: a comparison between their abilities to induce macrophage-mediated tumor cell killing and Limulus amebocyte lysate clotting.
-
Bacterial surface association of heat-labile enterotoxin through lipopolysaccharide after secretion via the general secretory pathway.
-
Baroreflex stimulation attenuates central but not peripheral inflammation in conscious endotoxemic rats.
-
Behçet's disease patients present high levels of deglycosylated anti-lipoteichoic acid IgG and high IL-8 production after lipoteichoic acid stimulation.
-
Beta-arrestin-2 regulates the development of allergic asthma.
-
Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
-
Blockade of tissue factor-factor X binding attenuates sepsis-induced respiratory and renal failure.
-
Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation.
-
Both systemic and local lipopolysaccharide (LPS) burden are associated with knee OA severity and inflammation.
-
Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats.
-
CARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomes.
-
CD14-dependent mechanism for endotoxin-mediated nitric oxide synthesis in murine macrophages.
-
CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes.
-
CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury.
-
CD40L expression in plasma of volunteers following LPS administration: A comparison between assay of CD40L on platelet microvesicles and soluble CD40L.
-
CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis.
-
CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells.
-
Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses.
-
Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells.
-
Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome.
-
Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.
-
Caulobacter lipid A is conditionally dispensable in the absence of fur and in the presence of anionic sphingolipids.
-
Characterisation of Neisseria gonorrhoeae in semen during urethral infection in men.
-
Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe.
-
Characterization of interleukin-1 production by microglia in culture.
-
Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene.
-
Characterization of the effects of endotoxin on macrophage tumor cell killing.
-
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis.
-
Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules.
-
Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation.
-
Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function.
-
Clara cells attenuate the inflammatory response through regulation of macrophage behavior.
-
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. I. A description of the technique and of methods for the analysis of colonies.
-
Cloning of mitogen- and antigen-reactive B lymphocytes on filter paper discs. II. Paratope frequencies within the mitogen-selected repertoire.
-
Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis.
-
Combining lung-protective strategies in experimental acute lung injury: The impact of high-frequency partial liquid ventilation.
-
Context-dependent activation kinetics elicited by soluble versus outer membrane vesicle-associated heat-labile enterotoxin.
-
Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells.
-
Cutting edge: Role of osteopontin and integrin αv in T cell-mediated anti-inflammatory responses in endotoxemia.
-
Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling.
-
Cyclosporine inhibition of CH series murine B-cell lymphomas.
-
Cyclosporine inhibition of a murine B cell lymphoma.
-
Cytokine induction of the ability of human monocyte CD44 to bind hyaluronan is mediated primarily by TNF-alpha and is inhibited by IL-4 and IL-13.
-
Cytokine production induced by Mycobacterium tuberculosis lipoarabinomannan. Relationship to chemical structure.
-
Cytokine regulation of liver injury and repair.
-
DNA and immunoglobulin synthesis by rabbit peripheral blood lymphocytes in vitro: complete and incomplete stimulation.
-
Dendritic cells stimulated with Actinobacillus actinomycetemcomitans elicit rapid gamma interferon responses by natural killer cells.
-
Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.
-
Determinants that govern the recognition and uptake of Escherichia coli O157 : H7 by Acanthamoeba castellanii.
-
Development of an on-line preconcentration method for the analysis of pathogenic lipopolysaccharides using capillary electrophoresis-electrospray mass spectrometry. Application to small colony isolates.
-
Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii.
-
Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease.
-
Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen.
-
Differential anti-inflammatory effects of LPS in susceptible and resistant mouse strains.
-
Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood.
-
Differential expression of intracellular and secreted osteopontin isoforms by murine macrophages in response to toll-like receptor agonists.
-
Differential gene expression of interleukin-1 receptor associated kinase-1 and interleukin-1 receptor associated kinase-M in peripheral blood mononuclear cells of young and aged rats following preconditioning with endotoxin.
-
Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma interferon production.
-
Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells.
-
Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy.
-
Does lipopolysaccharide-mediated inflammation have a role in OA?
-
Dopamine mediates vagal modulation of the immune system by electroacupuncture.
-
Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
-
Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood.
-
Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.
-
Effect of lipopolysaccharide administration on the number, phenotype and content of nuclear molecules in blood microparticles of normal human subjects.
-
Effects of Lipopolysaccharide on Human First Trimester Villous Cytotrophoblast Cell Function In Vitro.
-
Effects of bacterial lipopolysaccharide on the hydrolysis of phosphatidylinositol-4,5-bisphosphate in murine peritoneal macrophages.
-
Effects of induced tolerance to bacterial lipopolysaccharide on myocardial infarct size in rats.
-
Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
-
Elicitation of epithelial cell-derived immune effectors by outer membrane vesicles of nontypeable Haemophilus influenzae.
-
Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production.
-
Endothelial MKK3 is a critical mediator of lethal murine endotoxemia and acute lung injury.
-
Endotoxin (LPS) stimulates in vitro migration of macrophages from LPS-resistant mice but not from LPS-sensitive mice.
-
Endotoxin and NO induce MIP-1gamma gene transcription in ANA-1 murine macrophages.
-
Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression.
-
Endotoxin-induced uveitis in the rat: observations on altered vascular permeability, clinical findings, and histology.
-
Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages.
-
Endotoxin-mediated nitric oxide synthesis inhibits IL-1beta gene transcription in ANA-1 murine macrophages.
-
Endotoxin-mediated synthesis of nitric oxide is dependent on Gq protein signal transduction.
-
Endotoxin-stimulated Rat Hepatic Stellate Cells Induce Autophagy in Hepatocytes as a Survival Mechanism.
-
Endotoxin-stimulated nitric oxide production inhibits expression of cytochrome c oxidase in ANA-1 murine macrophages.
-
Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain.
-
Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation.
-
Enhanced expression of cytokines and chemokines by blood monocytes to in vitro lipopolysaccharide stimulation are associated with hostility and severity of depressive symptoms in healthy women.
-
Enhancement of macrophage-mediated tumor cell killing by bacterial outer membrane proteins (porins).
-
Environmental enrichment alters glial antigen expression and neuroimmune function in the adult rat hippocampus.
-
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation.
-
Exercise activates vagal induction of dopamine and attenuates systemic inflammation.
-
Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases.
-
Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens.
-
Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide.
-
Fatty liver vulnerability to endotoxin-induced damage despite NF-kappaB induction and inhibited caspase 3 activation.
-
Francisella FlmX broadly affects lipopolysaccharide modification and virulence.
-
Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling.
-
Functional Toll-like receptor 4 mutations modulate the response to fibrinogen.
-
Functional alterations of macrophages in autoimmune MRL-lpr/lpr mice.
-
Further characterization of a factor from endotoxin-treated serum which releases histamine and heparin from mast cells.
-
GPI-defective monocytes from paroxysmal nocturnal hemoglobinuria patients show impaired in vitro dendritic cell differentiation.
-
Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity.
-
Gene expression profiling of mouse bladder inflammatory responses to LPS, substance P, and antigen-stimulation.
-
Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.
-
Generation of a fibroblast chemotactic factor in serum by activation of complement.
-
Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity.
-
Genetic control of peripheral leukocyte response to endotoxin in mice.
-
Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice.
-
Globin attenuates the innate immune response to endotoxin.
-
Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70.
-
Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells.
-
Glutamine in acute lung injury: the experimental model matters.
-
Glutamine induces heat shock protein and protects against endotoxin shock in the rat.
-
Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia.
-
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.
-
Glycolysis-dependent histone deacetylase 4 degradation regulates inflammatory cytokine production.
-
Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity.
-
Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection.
-
Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.
-
HIV persistence in the gut mucosa of HIV-infected subjects undergoing antiretroviral therapy correlates with immune activation and increased levels of LPS.
-
HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration.
-
Heat-labile enterotoxin: beyond G(m1) binding.
-
Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection.
-
Human endometrial epithelial cells cyclically express Toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA.
-
Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.
-
Humoral autoimmunity to basement membrane antigens is regulated in C57BL/6 and MRL/MpJ mice transgenic for anti-laminin Ig receptors.
-
Humoral immune responses in L-selectin-deficient mice.
-
Hyaluronan fragments contribute to the ozone-primed immune response to lipopolysaccharide.
-
Identification of S-nitrosylated proteins in endotoxin-stimulated RAW264.7 murine macrophages.
-
Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma.
-
Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands.
-
Immunologic consequences of acute ethanol ingestion in rats.
-
In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production.
-
In vivo cytokine-associated responses to biomaterials.
-
In vivo modulation of macrophage tumoricidal activity: enhanced tumor cell killing by peritoneal macrophages from mice given injections of sodium periodate.
-
Increased coagulation and suppressed generation of activated protein C in aged mice during intra-abdominal sepsis.
-
Increases in stimulated secretion of proinflammatory cytokines by blood monocytes following arousal of negative affect: the role of insulin resistance as moderator.
-
Increasing the intracellular Na+ concentration induces differentiation in a pre-B lymphocyte cell line.
-
Inducible nitric oxide synthase expression by peritoneal macrophages in endometriosis-associated infertility.
-
Induction of Autophagy and Activation of SIRT-1 Deacetylation Mechanisms Mediate Neuroprotection by the Pomegranate Metabolite Urolithin A in BV2 Microglia and Differentiated 3D Human Neural Progenitor Cells.
-
Induction of an Inflammatory Response in Primary Hepatocyte Cultures from Mice.
-
Induction of ferritin and heme oxygenase-1 by endotoxin in the lung.
-
Induction of human dendritic cell maturation using transfection with RNA encoding a dominant positive toll-like receptor 4.
-
Induction of immune activation by a novel immunomodulatory oligonucleotide without thymocyte apoptosis.
-
Induction of superoxide anion and nitric oxide production in cultured microglia.
-
Infection-induced thrombin production: a potential novel mechanism for preterm premature rupture of membranes (PPROM).
-
Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins.
-
Inhibition of LPS toxicity for macrophages by metallothionein-inducing agents.
-
Inhibition of murine macrophage nitric oxide production by synthetic oligonucleotides.
-
Inhibition of neuroinflammation by thymoquinone requires activation of Nrf2/ARE signalling.
-
Inhibition of neuroinflammation in BV2 microglia by the biflavonoid kolaviron is dependent on the Nrf2/ARE antioxidant protective mechanism.
-
Inhibition of nitric oxide synthase inhibitors and lipopolysaccharide induced inducible NOS and cyclooxygenase-2 gene expressions by rutin, quercetin, and quercetin pentaacetate in RAW 264.7 macrophages.
-
Inhibition of tumor necrosis factor release from cultured rat Kupffer cells by agents that reduce graft failure from storage injury.
-
Inhibitor-kappaB kinase-beta regulates LPS-induced TNF-alpha production in cardiac myocytes through modulation of NF-kappaB p65 subunit phosphorylation.
-
Innate immune activation potentiates alloimmune lung disease independent of chemokine (C-X-C motif) receptor 3.
-
Intact nitric oxide synthase II gene is required for interferon-beta-mediated suppression of growth and metastasis of pancreatic adenocarcinoma.
-
Interaction of TLR2 and TLR4 ligands with the N-terminal domain of Gp96 amplifies innate and adaptive immune responses.
-
Interaction of complex polysaccharides with the complement system: effect of calcium depletion on terminal component consumption.
-
Interactions of the complement system with endotoxic lipopolysaccharide. Generation of a factor chemotactic for polymorphonuclear leukocytes.
-
Interactions of the complement system with endotoxic lipopolysaccharides in immunoglobulin-deficient sera.
-
Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice.
-
Intestinal alkaline phosphatase prevents metabolic syndrome in mice.
-
Ion fluxes and differentiation in transformed cell lines.
-
Kdo hydroxylase is an inner core assembly enzyme in the Ko-containing lipopolysaccharide biosynthesis.
-
Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1.
-
Ketamine potentiates oxidative stress and influences behavior and inflammation in response to lipolysaccharide (LPS) exposure in early life.
-
Kilohertz frequency nerve block enhances anti-inflammatory effects of vagus nerve stimulation.
-
LPS elicits a much larger and broader inflammatory response than Escherichia coli infection within the hippocampus of neonatal rats.
-
LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus.
-
LPS-sensory peptide communication in experimental cystitis.
-
Labeling of peripheral blood polymorphonuclear leukocytes with indium-111: a new method for the quantitation of in-vivo accumulation of PMNLs in rabbit skin.
-
Leptin regulates proinflammatory immune responses.
-
Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy.
-
Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy.
-
Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin.
-
Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis.
-
Lipopolysaccharide 3-deoxy-D-manno-octulosonic acid (Kdo) core determines bacterial association of secreted toxins.
-
Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock.
-
Lipopolysaccharide and phorbol esters induce differentiation but have opposite effects on phosphatidylinositol turnover and Ca2+ mobilization in 70Z/3 pre-B lymphocytes.
-
Lipopolysaccharide and soluble CD14 in cord blood plasma are associated with prematurity and chorioamnionitis.
-
Lipopolysaccharide bilayer structure: effect of chemotype, core mutations, divalent cations, and temperature.
-
Lipopolysaccharide facilitates partner preference behaviors in female prairie voles.
-
Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis.
-
Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1.
-
Lipopolysaccharide up-regulates platelet-derived growth factor (PDGF) alpha-receptor expression in rat lung myofibroblasts and enhances response to all PDGF isoforms.
-
Lipopolysaccharide upregulates bradykinin 1 receptors in the isolated mouse bladder.
-
Lipopolysaccharide-induced expression of TRAIL promotes dendritic cell differentiation.
-
Lipopolysaccharides in bacterial membranes act like cholesterol in eukaryotic plasma membranes in providing protection against melittin-induced bilayer lysis.
-
Low-dose aspirin prevents LPS-induced preeclampsia-like phenotype via AQP-1 and the MAPK/ERK 1/2 pathway.
-
Lung inflammation stalls Th17-cell migration en route to the central nervous system during the development of experimental autoimmune encephalomyelitis.
-
Lymphangitis after self-administration of lipopolysaccharide.
-
Lymphoma models for B cell activation and tolerance. V. Anti-Ig mediated growth inhibition is reversed by phorbol myristate acetate but does not involve changes in cytosolic free calcium.
-
MKK3 mediates inflammatory response through modulation of mitochondrial function.
-
MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury.
-
Macrophage activation downregulates the degradative capacity of the phagosome.
-
Macrophage polykaryon formation in vitro by peritoneal cells from mice given injections of sodium periodate.
-
Mapping bacterial glycolipid complexity using capillary electrophoresis and electrospray mass spectrometry.
-
Maternal aggression persists following lipopolysaccharide-induced activation of the immune system.
-
Mature macrophage cell lines exhibit variable responses to LPS.
-
Mechanism of immune response during immunotherapy.
-
Mechanisms of polyclonal B-cell activation in autoimmune B6-lpr/lpr mice.
-
Mediators of pulmonary injury induced by inhalation of bacterial endotoxin.
-
Melatonin regulates energy balance and attenuates fever in Siberian hamsters.
-
Memory B cell responses to Vibrio cholerae O1 lipopolysaccharide are associated with protection against infection from household contacts of patients with cholera in Bangladesh.
-
Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes.
-
Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon.
-
Microglia and memory: modulation by early-life infection.
-
Microglial function in human APOE3 and APOE4 transgenic mice: altered arginine transport.
-
Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production.
-
Modulation of lymphocyte functions by group A streptococcal membrane.
-
Modulation of neuroinflammation and memory dysfunction using percutaneous vagus nerve stimulation in mice.
-
Modulation of the tumoricidal function of activated macrophages by bacterial endotoxin and mammalian macrophage activation factor (s).
-
Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation.
-
Morphometric changes of the lung induced by inhaled bacterial endotoxin.
-
Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male.
-
Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system.
-
Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis.
-
Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b.
-
NF-kappa B and transcriptional control of renal epithelial-inducible nitric oxide synthase.
-
NF-kappaB factors are essential, but not the switch, for pathogen-related induction of the bovine beta-defensin 5-encoding gene in mammary epithelial cells.
-
NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages.
-
NOS2 regulation of LPS-induced airway inflammation via S-nitrosylation of NF-{kappa}B p65.
-
Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation.
-
Naturally produced outer membrane vesicles from Pseudomonas aeruginosa elicit a potent innate immune response via combined sensing of both lipopolysaccharide and protein components.
-
Neonatal bacterial infection alters fever to live and simulated infections in adulthood.
-
Neonatal immune challenge induces female-specific changes in social behavior and somatostatin cell number.
-
Neonatal infection induces memory impairments following an immune challenge in adulthood.
-
Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition.
-
Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.
-
New tools for studying microglia in the mouse and human CNS.
-
Nitric oxide and prostaglandin E2 participate in lipopolysaccharide/interferon-gamma-induced heme oxygenase 1 and prevent RAW264.7 macrophages from UV-irradiation-induced cell death.
-
Nitric oxide inhibits expression of cytochrome B in endotoxin-stimulated murine macrophages.
-
Nitric oxide is necessary for CC-class chemokine expression in endotoxin-stimulated ANA-1 murine macrophages.
-
Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice.
-
Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways.
-
Nitric oxide-dependent ribosomal RNA cleavage is associated with inhibition of ribosomal peptidyl transferase activity in ANA-1 murine macrophages.
-
Non-erythroid effects of erythropoietin.
-
Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis.
-
Novel Murine Models of Cerebral Cavernous Malformations.
-
Nuclear factor kappa B mediates lipopolysaccharide-induced inflammation in the urinary bladder.
-
Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis.
-
Ocular albumin fluorophotometric quantitation of endotoxin-induced vascular permeability.
-
Osteopontin and protein kinase C regulate PDLIM2 activation and STAT1 ubiquitination in LPS-treated murine macrophages.
-
Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages.
-
Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages.
-
Outer Membrane Vesicle Production Facilitates LPS Remodeling and Outer Membrane Maintenance in Salmonella during Environmental Transitions.
-
Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein.
-
Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism.
-
Ozone primes alveolar macrophage-derived innate immunity in healthy human subjects.
-
P- and L-selectin mediate distinct but overlapping functions in endotoxin-induced leukocyte-endothelial interactions in the rat mesenteric microcirculation.
-
PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking.
-
Periodontal disease: a model for the study of inflammation.
-
Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter.
-
Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis.
-
Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production.
-
Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange.
-
Photoperiod alters the time course of brain cyclooxygenase-2 expression in Siberian hamsters.
-
Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate.
-
Placental Macrophages: A Window Into Fetal Microglial Function in Maternal Obesity.
-
Plant stomata function in innate immunity against bacterial invasion.
-
Platelet procoagulant complex assembly in a tissue factor-initiated system.
-
Polarized monocyte response to cytokine stimulation.
-
Post-transcriptional inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by Gö6976 in murine microglia.
-
Postlipopolysaccharide oxidative damage of mitochondrial DNA.
-
Preparation and preclinical evaluation of a novel liposomal complete-core lipopolysaccharide vaccine.
-
Prevention of acute lung injury in swine: depletion of pulmonary intravascular macrophages using liposomal clodronate.
-
Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation.
-
Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats.
-
Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation.
-
Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes.
-
Protective effects of heme oxygenase-1 in acute lung injury.
-
Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure.
-
Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation.
-
Punicalagin inhibits neuroinflammation in LPS-activated rat primary microglia.
-
Quantification of mouse macrophage chemotaxis in vitro: role of C5 for the production of chemotactic activity.
-
RNase L Is Involved in Liposaccharide-Induced Lung Inflammation.
-
Rapid phosphoproteomic and transcriptomic changes in the rhizobia-legume symbiosis.
-
Recombinant HMGB1 with cytokine-stimulating activity.
-
Recruited exudative macrophages selectively produce CXCL10 after noninfectious lung injury.
-
Reduced peripheral PGE2 biosynthesis in Plasmodium falciparum malaria occurs through hemozoin-induced suppression of blood mononuclear cell cyclooxygenase-2 gene expression via an interleukin-10-independent mechanism.
-
Reduced stress defense in heme oxygenase 1-deficient cells.
-
Regulation of I-309 gene expression in human monocytes by endogenous interleukin-1.
-
Regulation of corneal inflammation by neutrophil-dependent cleavage of keratan sulfate proteoglycans as a model for breakdown of the chemokine gradient.
-
RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts.
-
Residues of heat-labile enterotoxin involved in bacterial cell surface binding.
-
Resistance of CD7-deficient mice to lipopolysaccharide-induced shock syndromes.
-
Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels.
-
Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury.
-
Retrovirus-elicited interleukin-12 and tumour necrosis factor-alpha as inducers of interferon-gamma-mediated pathology in mouse AIDS.
-
Role of C-C motif ligand 2 and C-C motif receptor 2 in murine pulmonary graft-versus-host disease after lipopolysaccharide inhalations.
-
Role of fibrinopeptide B in early atherosclerotic lesion formation.
-
Role of interleukin-1beta in postoperative cognitive dysfunction.
-
Role of thromboxane A2 in the induction of apoptosis of immature thymocytes by lipopolysaccharide.
-
S-Nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase
-
SMAD4 is required for development of maximal endotoxin tolerance.
-
SNX10 and caspase-5 sort out endosomal LPS for a gut-wrenching Slug-fest.
-
Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.
-
Sex steroid hormones enhance immune function in male and female Siberian hamsters.
-
Short day lengths attenuate the symptoms of infection in Siberian hamsters.
-
Significance of complement to the mechanism of action of endotoxin.
-
Skewed VH and V kappa gene family expression and pairing occurs among B lymphocytes in autoimmune motheaten mice.
-
Sleep and fatigue in mice infected with murine gammaherpesvirus 68.
-
Social status alters immune regulation and response to infection in macaques.
-
Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis.
-
Sphingosine inhibits monocyte tissue factor-initiated coagulation by altering factor VII binding.
-
Spontaneous tumor cell killing by human blood monocytes and human peritoneal macrophages: lack of alteration by endotoxin or quenchers of reactive oxygen species.
-
Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression.
-
Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA.
-
Stimulation of ovarian tumor cell proliferation with monocyte products including interleukin-1, interleukin-6, and tumor necrosis factor-alpha.
-
Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice.
-
Streptococcus pneumoniae, S. mitis, and S. oralis Produce a Phosphatidylglycerol-Dependent, ltaS-Independent Glycerophosphate-Linked Glycolipid.
-
Structural basis for the proinflammatory cytokine activity of high mobility group box 1.
-
Structure of supported bilayers composed of lipopolysaccharides and bacterial phospholipids: raft formation and implications for bacterial resistance.
-
Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule.
-
Substance P and calcitonin gene-related peptide increase IL-1 beta, IL-6 and TNF alpha secretion from human peripheral blood mononuclear cells.
-
Suppression of lipopolysaccharide-stimulated release of tumor necrosis factor by adenosine: evidence for A2 receptors on rat Kupffer cells.
-
Surface array proteins of Campylobacter fetus block lectin-mediated binding to type A lipopolysaccharide.
-
Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.
-
Surfactant protein A modulates induction of regulatory T cells via TGF-β.
-
Sustenance of endothelial cell stability in septic mice through appropriate activation of transient receptor potential vanilloid-4.
-
Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IkappaB kinase.
-
TLR4-mediated expulsion of bacteria from infected bladder epithelial cells.
-
TNF, IFN-gamma, and endotoxin increase expression of DMT1 in bronchial epithelial cells.
-
TT-301 inhibits microglial activation and improves outcome after central nervous system injury in adult mice.
-
Temporal Patterns in Sheep Fetal Heart Rate Variability Correlate to Systemic Cytokine Inflammatory Response: A Methodological Exploration of Monitoring Potential Using Complex Signals Bioinformatics.
-
The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation.
-
The HIV-1 protease inhibitor nelfinavir activates PP2 and inhibits MAPK signaling in macrophages: a pathway to reduce inflammation.
-
The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia.
-
The United States National Prospective Hemolytic Uremic Syndrome Study: microbiologic, serologic, clinical, and epidemiologic findings.
-
The biological activity of a liposomal complete core lipopolysaccharide vaccine.
-
The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation.
-
The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals.
-
The effect of active site-inhibited factor VIIa on tissue factor-initiated coagulation using platelets before and after aspirin administration.
-
The effect of covalently immobilized rhIL-1ra-ELP fusion protein on the inflammatory profile of LPS-stimulated human monocytes.
-
The effects of CpG DNA on HMGB1 release by murine macrophage cell lines.
-
The expression of plasma nucleosomes in mice undergoing in vivo apoptosis.
-
The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens.
-
The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation.
-
The immune system and developmental programming of brain and behavior.
-
The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction.
-
The indolocarbazole Gö6976 protects neurons from lipopolysaccharide/interferon-gamma-induced cytotoxicity in murine neuron/glia co-cultures.
-
The influence of lipofectin on the in vitro stimulation of murine spleen cells by bacterial DNA and plasmid DNA vectors.
-
The linker for activation of B cells (LAB)/non-T cell activation linker (NTAL) regulates triggering receptor expressed on myeloid cells (TREM)-2 signaling and macrophage inflammatory responses independently of the linker for activation of T cells.
-
The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics.
-
The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair.
-
The posterior cricoarytenoid muscle is spared from MuRF1-mediated muscle atrophy in mice with acute lung injury.
-
The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice.
-
The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis.
-
The relation of aggression, hostility, and anger to lipopolysaccharide-stimulated tumor necrosis factor (TNF)-alpha by blood monocytes from normal men.
-
The relation of severity of depressive symptoms to monocyte-associated proinflammatory cytokines and chemokines in apparently healthy men.
-
The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid.
-
The release of microparticles by RAW 264.7 macrophage cells stimulated with TLR ligands.
-
The role of IFN-alpha and nitric oxide in the release of HMGB1 by RAW 264.7 cells stimulated with polyinosinic-polycytidylic acid or lipopolysaccharide.
-
The role of Toll-like receptor 4 in environmental airway injury in mice.
-
The role of ion fluxes in hematopoietic cell differentiation.
-
The role of the extracellular matrix protein mindin in airway response to environmental airways injury.
-
The role of tuberous sclerosis complex 1 in regulating innate immunity.
-
The transcriptomic response of rat hepatic stellate cells to endotoxin: implications for hepatic inflammation and immune regulation.
-
The upregulation of specific interleukin (IL) receptor antagonists and paradoxical enhancement of neuronal apoptosis due to electrode induced strain and brain micromotion.
-
Thioredoxin-mediated denitrosylation regulates cytokine-induced nuclear factor κB (NF-κB) activation.
-
Thrombin enhances monocyte secretion of tumor necrosis factor and interleukin-1 beta by two distinct mechanisms.
-
Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages.
-
Time course of LPS-induced gene expression in a mouse model of genitourinary inflammation.
-
Toll-like receptor 4 (TLR4)-deficient murine macrophage cell line as an in vitro assay system to show TLR4-independent signaling of Bacteroides fragilis lipopolysaccharide.
-
Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide.
-
Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin.
-
Transplant approach establishes that kidneys are responsible for serum CSF-1 but require a stimulus in MRL-lpr mice.
-
Treatment of murine peritoneal macrophages with bacterial lipopolysaccharide alters expression of c-fos and c-myc oncogenes.
-
Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli.
-
Two forms of NF-kappa B1 (p105/p50) in murine macrophages: differential regulation by lipopolysaccharide, interleukin-2, and interferon-gamma.
-
Tyrosine phosphorylation-independent regulation of lipopolysaccharide-mediated response by the transmembrane adaptor protein LAB.
-
Variation in DNA and RNA synthetic responses during activation of lymphocytes from inbred strains of mice.
-
Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury.
-
Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection.
-
Visualization and characterization of inflammatory cell recruitment and migration through the corneal stroma in endotoxin-induced keratitis.
-
WildCARDs: inflammatory caspases directly detect LPS.
-
[Effects of intravenous anesthetics on LPS-induced production of tumour necrosis factor-alpha from primary cultures of rat glial cells in vitro].
-
[Protective effect of SNMC on mice with fulminant liver failure].
-
[THE ENZYMES OF THE LEUKOCYTE].
-
cDNA array of lipopolysaccharide-induced bladder gene expression.
-
cDNA expression arrays: the effects of lactacystin in lipopolysaccharide-induced cystitis.
-
Keywords of People
-
Chen, Jun,
Professor of Medicine,
Duke Cancer Institute
-
Guan, Ziqiang,
Research Professor in Biochemistry,
Biochemistry
-
Gunn, Michael Dee,
Professor of Medicine,
Immunology
-
Kelsoe, Garnett H.,
James B. Duke Distinguished Professor of Immunology,
Immunology
-
Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Immunology
-
Kuehn, Margarethe Joanna,
Associate Professor of Biochemistry,
Cell Biology
-
Laskowitz, Daniel Todd,
Professor of Neurology,
Duke Science & Society
-
Muir, Kelly Walton,
Associate Professor of Ophthalmology,
Ophthalmology, Glaucoma
-
Pastva, Amy Martha,
Professor in Orthopaedic Surgery,
Cell Biology
-
Shinohara, Mari L.,
Associate Professor of Immunology,
Cell Biology