Lipoproteins

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  Subject Areas on Research

  • A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion. 
  • A Novel Protein Glycan-Derived Inflammation Biomarker Independently Predicts Cardiovascular Disease and Modifies the Association of HDL Subclasses with Mortality. 
  • A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. 
  • A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. 
  • A regression model for longitudinal change in the presence of measurement error. 
  • ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation. 
  • Acute changes in serum lipids and lipoprotein subclasses in triathletes as assessed by proton nuclear magnetic resonance spectroscopy. 
  • Acute reduction of lipoprotein(a) by tissue-type plasminogen activator. 
  • Adrenergic effects on plasma lipoprotein metabolism. Speculation on mechanisms of action. 
  • Advanced lipoprotein testing does not improve identification of subclinical atherosclerosis in young adults: the Bogalusa Heart Study. 
  • Altered lipoprotein subclass distribution and PAF-AH activity in subjects with generalized aggressive periodontitis. 
  • An adverse lipoprotein phenotype-hypertriglyceridaemic hyperapolipoprotein B-and the long-term risk of type 2 diabetes: a prospective, longitudinal, observational cohort study. 
  • Angiotensin converting enzyme inhibitors and the cardiovascular system. 
  • Antifungal treatment in pediatric patients. 
  • Apolipoprotein E-deficient mice created by systemic administration of antisense oligodeoxynucleotides: a new model for lipoprotein metabolism studies. 
  • Association of Apolipoprotein B-Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis: Distinguishing Between Particle Concentration, Type, and Content. 
  • Association of levels of lipoprotein Lp(a), plasma lipids, and other lipoproteins with coronary artery disease documented by angiography. 
  • Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. 
  • Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident Dyslipidemia in US Adults: The Framingham Heart Study. 
  • Ca(2+)-dependent interaction of recoverin with rhodopsin kinase. 
  • Changes in lipid values and lipoprotein patterns of serum samples contaminated with bacteria. 
  • Changes in plasma lipid and lipoprotein levels in men and women after a program of moderate exercise. 
  • Characterization of the Vibrio cholerae VolA surface-exposed lipoprotein lysophospholipase. 
  • Comparison of a reduced carbohydrate and reduced fat diet for LDL, HDL, and VLDL subclasses during 9-months of weight maintenance subsequent to weight loss. 
  • Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints. 
  • Detection of dyslipoproteinemia with the use of plasma total cholesterol and triglyceride as screening tests. The Lipid Research Clinics Program Prevalence Study. 
  • Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model. 
  • Development of the lipid-rich core in human atherosclerosis. 
  • Differential changes in plasma high-density lipoprotein-cholesterol levels in obese men and women during weight reduction 
  • Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms. 
  • Does a lack of physical activity explain the rheumatoid arthritis lipid profile? 
  • Dyslipoproteinemia and premature atherosclerosis in pediatric systemic lupus erythematosus. 
  • Early statin initiation and outcomes in patients with acute coronary syndromes. 
  • Effect of a low-carbohydrate, ketogenic diet program compared to a low-fat diet on fasting lipoprotein subclasses. 
  • Effects of Resmetirom on Noninvasive Endpoints in a 36-Week Phase 2 Active Treatment Extension Study in Patients With NASH. 
  • Effects of a single bout of ultraendurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes. 
  • Effects of aerobic training with and without weight loss on insulin sensitivity and lipids. 
  • Effects of estrogen/progestin agents on plasma retinoids and chylomicron remnant metabolism. 
  • Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women. 
  • Effects of the amount and intensity of exercise on plasma lipoproteins. 
  • Estrogen induction of plasma vitellogenin in the cockerel: studies with a phosvitin antibody. 
  • Exercise and atherosclerotic heart disease in women. 
  • Extended-release niacin for modifying the lipoprotein profile. 
  • Fasting might not be necessary before lipid screening: a nationally representative cross-sectional study. 
  • Frequency of physical activity, exercise capacity, and atherosclerotic heart disease risk factors in male police officers. 
  • From the editor: Lessons from the East. 
  • Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein a compete for the same site. 
  • Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipoproteins. 
  • Heparin-associated anti-Xa activity and platelet-derived prothrombotic and proinflammatory biomarkers in moderate to high-risk patients with acute coronary syndrome. 
  • Heterozygous ABCG5 Gene Deficiency and Risk of Coronary Artery Disease. 
  • High prevalence of low HDL-c in the Philippines compared to the US: population differences in associations with diet and BMI. 
  • High-sensitivity C-reactive protein elevation in patients with prior myocardial infarction in the United States. 
  • Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice. 
  • Hypolipidemic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis(trimethylamin e- carboxyborane)-dicopper(II) in rodents and its effect on lipid metabolism. 
  • Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI). 
  • Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion. 
  • Impact of hormone replacement therapy on exercise training-induced improvements in insulin action in sedentary overweight adults. 
  • Impact on cardiometabolic risk of a weight loss intervention with higher protein from lean red meat: Combined results of 2 randomized controlled trials in obese middle-aged and older adults. 
  • Inactivity, exercise training and detraining, and plasma lipoproteins. STRRIDE: a randomized, controlled study of exercise intensity and amount. 
  • Is nuclear magnetic resonance lipoprotein subclass related to diabetic retinopathy? The multi-ethnic study of atherosclerosis (MESA). 
  • Isolation and characterization of the two major apoproteins in human lipoprotein [a]. 
  • JCL roundtable: Lipids and inflammation in atherosclerosis. 
  • Kinetic analysis of the effects of glycosaminoglycans and lipoproteins on urokinase-mediated plasminogen activation. 
  • Kinetic analysis of the effects of heparin and lipoproteins on tissue plasminogen activator mediated plasminogen activation. 
  • Left atrial enlargement: a cause of stroke? 
  • Letter by Sniderman et al Regarding Article, "Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease". 
  • Lipids and Their Effects in Chronic Lymphocytic Leukemia. 
  • Lipids and stroke: a paradox resolved. 
  • Lipoprotein (a) promotes plasmin inhibition by alpha 2-antiplasmin. 
  • Lipoprotein Subclasses Associated With High-Risk Coronary Atherosclerotic Plaque: Insights From the PROMISE Clinical Trial. 
  • Lipoprotein a inhibits streptokinase-mediated activation of human plasminogen. 
  • Lipoprotein response to exercise training and a low-fat diet in older subjects with glucose intolerance. 
  • Lipoprotein synthesis in the cockerel liver: effects of estrogen on hepatic polysomal messenger ribonucleic acid activities for the major apoproteins in very loow and high density lipoproteins and for albumin and evidence for precursors to these secretory proteins. 
  • Lipoprotein(a) and apolipoproteins B and A-I after acute myocardial infarction. 
  • Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator. 
  • Lipoprotein(a) inhibits plasminogen activation in a template-dependent manner. 
  • Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization. 
  • Localization of three genes expressed in retina on mouse chromosome 11. 
  • Long-term safety and efficacy of triple combination ezetimibe/simvastatin plus extended-release niacin in patients with hyperlipidemia. 
  • Lyme disease vaccination: are we ready to try again? 
  • Lyme disease vaccination: safety first - author's reply. 
  • Manganese-porphyrin reactions with lipids and lipoproteins. 
  • Mechanism of the interaction of hypertension and hypercholesterolemia in atherogenesis: the effects of antihypertensive agents. 
  • Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. 
  • Metabolic syndrome: evaluation of pathological and therapeutic outcomes. 
  • Micafungin: the US perspective. 
  • Modulation of bacterial outer membrane vesicle production by envelope structure and content. 
  • Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors. 
  • Molecular Detection and Typing of Pathogenic Leptospira in Febrile Patients and Phylogenetic Comparison with Leptospira Detected among Animals in Tanzania. 
  • NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. 
  • NlpI-mediated modulation of outer membrane vesicle production through peptidoglycan dynamics in Escherichia coli. 
  • Novel plasma biomarkers improve discrimination of metabolic health independent of weight. 
  • Omega-3 fatty acids in cardiac biopsies from heart transplantation patients: correlation with erythrocytes and response to supplementation. 
  • Outcomes of biomarker feedback on physical activity, eating habits, and emotional health: from the Americans in Motion-Healthy Intervention (AIM-HI) study. 
  • Outer membrane protein I of Pseudomonas aeruginosa is a target of cationic antimicrobial peptide/protein. 
  • Pattern of serum protein gene expression in mouse visceral yolk sac and foetal liver. 
  • Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant. 
  • Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL). 
  • Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration. 
  • Plasma lipoproteins of free-ranging howling monkeys (Alouatta palliata). 
  • Plasmin-mediated proteolysis of vascular endothelial cell heparin releasable tissue factor pathway inhibitor. 
  • Premature atherosclerosis in pediatric systemic lupus erythematosus: risk factors for increased carotid intima-media thickness in the atherosclerosis prevention in pediatric lupus erythematosus cohort. 
  • Priming for virus-specific CD8+ but not CD4+ cytotoxic T lymphocytes with synthetic lipopeptide is influenced by acylation units and liposome encapsulation. 
  • Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse. 
  • Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice. 
  • Racial differences of lipoprotein subclass distributions in postmenopausal women. 
  • Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina. 
  • Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors. 
  • Red Blood Cells and Lipoproteins: Important Reservoirs and Transporters of Polyphenols and Their Metabolites. 
  • Regulation of lipoprotein metabolism by adrenergic mechanisms. 
  • Regulation of lipoprotein synthesis. Studies on the molecular mechanisms of lipoprotein synthesis and their regulation by estrogen in the cockerel. 
  • Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy. 
  • Relations of GlycA and lipoprotein particle subspecies with cardiovascular events and mortality: A post hoc analysis of the AIM-HIGH trial. 
  • Relationship between resolution of non-alcoholic steatohepatitis and changes in lipoprotein sub-fractions: a post-hoc analysis of the PIVENS trial. 
  • Relationship of job strain to standard coronary risk factors and psychological characteristics in women and men of the Family Heart Study. 
  • Relationship of lipoproteins to cardiovascular events: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes). 
  • Relationship of plasma lipoprotein Lp(a) levels to race and to apolipoprotein B. 
  • Safety considerations with niacin therapy. 
  • Serum lipids in the GENECARD study of coronary artery disease identify quantitative trait loci and phenotypic subsets on chromosomes 3q and 5q. 
  • Smooth muscle growth and cholesterol accumulation in atherogenesis. 
  • Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys. 
  • Sphingolipid biosynthesis by rat liver cells: effects of serine, fatty acids and lipoproteins. 
  • Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. 
  • Statin therapy and inflammation in patients with diabetes treated with high dose aspirin. 
  • Stress and lipoprotein metabolism: modulators and mechanisms. 
  • Studies of a targeted risk reduction intervention through defined exercise (STRRIDE). 
  • Substrate binding is required for release of product from mammalian protein farnesyltransferase. 
  • Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin. 
  • Synthetic effect between envelope stress and lack of outer membrane vesicle production in Escherichia coli. 
  • The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor. 
  • The association of dyslipoproteinemia with corneal arcus and xanthelasma. The Lipid Research Clinics Program Prevalence Study. 
  • The effects of exercise on the lipoprotein subclass profile: A meta-analysis of 10 interventions. 
  • The inhibition of tissue type plasminogen activator by plasminogen activator inhibitor-1. The effects of fibrinogen, heparin, vitronectin, and lipoprotein(a). 
  • The outer surface lipoprotein VolA mediates utilization of exogenous lipids by Vibrio cholerae. 
  • The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates. 
  • The relation of hostility to lipids and lipoproteins in women: evidence for the role of antagonistic hostility. 
  • The role of lipoproteins in atherogenesis. 
  • The vulnerable endothelium: priming the vascular endothelium for thrombosis with unfractionated heparin: biologic plausibility for observations from the Superior Yield of the New Strategy of Enoxaparin, Revascularization and GlYcoprotein IIb/IIIa Inhibitors (SYNERGY) trial. 
  • Thrombin activates factor XI on activated platelets in the absence of factor XII. 
  • Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway. 
  • Transplantation of full-thickness retina in the rhodopsin transgenic pig. 
  • U.S.S.R. and U.S. nutrient intake, plasma lipids, and lipoproteins in men ages 40-59 sampled from Lipid Research Clinics populations. 
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  Keywords of People

  • Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
  • Guan, Ziqiang, Research Professor in Biochemistry, Biochemistry
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Kuehn, Margarethe Joanna, Associate Professor of Biochemistry, Cell Biology
  • Schanberg, Laura Eve, Professor of Pediatrics, Pediatrics, Rheumatology
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Yancy Jr., William Samuel, Professor of Medicine, Medicine, General Internal Medicine