Liver Neoplasms

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  Subject Areas on Research

  • A Technique for Generating Volumetric Cine-Magnetic Resonance Imaging. 
  • A case of curative-intent hepatectomy for colon cancer metastatic to the scapula and liver. 
  • A case-control method for assessing environmental risks from multiple industrial point sources. 
  • A comparison of antiangiogenic therapies for the prevention of liver metastases. 
  • A generic framework to simulate realistic lung, liver and renal pathologies in CT imaging. 
  • A new syndrome: ascites, hyperbilirubinemia, and hypoalbuminemia after biochemical modulation of fluorouracil with N-phosphonacetyl-L-aspartate (PALA) 
  • A niche role for cancer exosomes in metastasis. 
  • A phase I-II trial of mitoxantrone by hepatic arterial infusion in patients with hepatocellular carcinoma or colorectal carcinoma metastatic to the liver. 
  • A phase I/II trial of TAC-101, an oral synthetic retinoid, in patients with advanced hepatocellular carcinoma. 
  • A phase II study of docetaxel-irinotecan combination in advanced pancreatic cancer. 
  • A pilot study of hepatic artery floxuridine combined with systemic 5-fluorouracil and leucovorin. A potential adjuvant program after resection of colorectal hepatic metastases. 
  • A pressing situation. 
  • A randomized trial of intrahepatic infusion of fluorodeoxyuridine with dexamethasone versus fluorodeoxyuridine alone in the treatment of metastatic colorectal cancer. 
  • A reversible enteropathy complicating continuous hepatic artery infusion chemotherapy with 5-fluoro-2-deoxyuridine. 
  • A role for hepatic metastasectomy in stage IV melanoma and breast cancer: reestablishing the surgical modality. 
  • A segmental approach to computerized tomographic portography for hepatic resection. 
  • A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element. 
  • Acoustic radiation force elasticity imaging in diagnostic ultrasound. 
  • Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility. 
  • Acoustic radiation force impulse imaging of thermally- and chemically-induced lesions in soft tissues: preliminary ex vivo results. 
  • Acquisition of glutamine synthetase expression in human hepatocarcinogenesis: relation to disease recurrence and possible regulation by ubiquitin-dependent proteolysis. 
  • Acting in the face of uncertainty. 
  • Actual 10-year survival following hepatectomy for hepatocellular carcinoma. 
  • Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases. 
  • Adenocarcinoma of the liver without a detectable primary. 
  • Adjuvant chemotherapy for patients with primary hepatocellular carcinoma: a meta-analysis. 
  • Adjuvant hepatic arterial chemotherapy following metastasectomy in patients with isolated liver metastases. 
  • Adoption of Splenic Enhancement to Time and Trigger the Late Hepatic Arterial Phase During MDCT of the Liver: Proof of Concept and Clinical Feasibility. 
  • Age differences in care practices and outcomes for hospitalized patients with cancer. 
  • Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus. 
  • Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements. 
  • An improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo. 
  • An international survey on liver metastases radiotherapy. 
  • Analysis of tumor characteristics and survival in liver transplant recipients with incidentally diagnosed hepatocellular carcinoma. 
  • Animal models of human colorectal cancer: Current status, uses and limitations. 
  • Annual literature review for clinical transplants 2005. 
  • Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. 
  • Antioxidants and prevention of gastrointestinal cancers. 
  • Apoptosis and cytokines in non-alcoholic steatohepatitis. 
  • Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasiveness. 
  • Association between hypothyroidism and hepatocellular carcinoma: a case-control study in the United States. 
  • Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma. 
  • Bevacizumab-associated fistula formation in postoperative colorectal cancer patients. 
  • Breath-hold three-dimensional CT of the liver with multi-detector row helical CT. 
  • Bridging Locoregional Therapy Prolongs Survival in Patients Listed for Liver Transplant with Hepatocellular Carcinoma. 
  • CT arterial portography: causes of technical failure and variable liver enhancement. 
  • CT during arterial portography: diagnostic pitfalls. 
  • CT of fundoplication. 
  • Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice. 
  • Carcinoid metastases to the liver: role of triple-phase helical CT. 
  • Carcinoid tumors of the gastrointestinal tract. A review and the Duke University institutional overview. 
  • Case 23-2005: a man with a mass in the liver. 
  • Case report. Intrabiliary colonic metastasis mimicking primary biliary neoplasia. 
  • Cases from the Osler Medical Service at Johns Hopkins University. 
  • Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology. 
  • Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity. 
  • Challenges in screening for hepatocellular carcinoma in the glycogen storage disease type 1a population. 
  • Challenging choices: liver transplantation for hepatocellular carcinoma. 
  • Characterization and pathogenesis of anemia in glycogen storage disease type Ia and Ib. 
  • Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy. 
  • Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease. 
  • Cirrhosis of the liver in long-term marrow transplant survivors. 
  • Cisplatin and 5-fluorouracil infusion for metastatic colorectal carcinoma. Differences in survival in two patient groups with similar response rates. 
  • Clear cell sarcoma of the gastrointestinal tract after very low-dose therapeutic radiation therapy: a case report. 
  • Clinical and pharmacologic effects of high dose single agent busulfan with autologous bone marrow support in the treatment of solid tumors. 
  • Clinical and prognostic implications of plasma insulin-like growth factor-1 and vascular endothelial growth factor in patients with hepatocellular carcinoma. 
  • Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique. 
  • Clinical studies on the radioimmunodetection of tumors containing alpha-fetoprotein. 
  • Clinico-pathologic conference: 12-year-old girl with fatigue, anemia, weight loss, abdominal distention, and occasional nausea and vomiting. 
  • Clostridium septicum abscess in hepatic metastases: successful medical management. 
  • Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest a novel target for breast-specific antiestrogen therapy. 
  • Colon cancer, version 3.2014. 
  • Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment. 
  • Colorectal liver metastasis after 90Y radioembolization therapy: pilot study of change in MDCT attenuation as a surrogate marker for future FDG PET response. 
  • Combined CT arterial portography and CT hepatic angiography for evaluation of the hepatic resection candidate. Work in progress. 
  • Combined hepatocellular-cholangiocarcinoma: a population-level analysis of an uncommon primary liver tumor. 
  • Comparison of three physiologically-based pharmacokinetic models for the prediction of contrast agent distribution measured by dynamic MR imaging. 
  • Comparison of unenhanced, hepatic arterial-dominant, and portal venous-dominant phase helical CT for the detection of liver metastases in women with breast carcinoma. 
  • Computed tomographic detection of gas within spontaneously necrotic tissue. 
  • Computed tomography in the detection of abdominal metastases from malignant melanoma. 
  • Computed tomography of primary liver tumors in children. 
  • Concentration of Tc-99m methylenediphosphonate in hepatic metastases from squamous cell carcinoma. 
  • Concordance of hypervascular liver nodule characterization between the organ procurement and transplant network and liver imaging reporting and data system classifications. 
  • Consensus report from the 7th International Forum for Liver Magnetic Resonance Imaging. 
  • Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic. 
  • Contemporary surgical options for metastatic colorectal cancer. 
  • Cryosurgery after chemoembolization for hepatocellular carcinoma in patients with cirrhosis. 
  • Cryosurgical debulking of unresectable liver metastases for palliation of carcinoid syndrome. 
  • Cytoablative therapy with combined resection and cryosurgery for limited bilobar hepatic colorectal metastases. 
  • Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy in patients with peritoneal hepatocellular carcinoma. 
  • Decreased detection of hypovascular liver tumors with MDCT in obese patients: a phantom study. 
  • Depression of macrophage function by a factor produced by neoplasms: a merchanism for abrogation of immune surveillance. 
  • Desmoplastic small round cell tumor: using FISH as an ancillary technique to support cytologic diagnosis in an unusual case. 
  • Detection of focal hepatic masses: STIR MR vs. CT during arterial portography. 
  • Detection of hepatic metastases from colorectal cancer: prospective evaluation of gray scale US versus SonoVue® low mechanical index real time-enhanced US as compared with multidetector-CT or Gd-BOPTA-MRI. 
  • Determining the optimal block margin on the planning target volume for extracranial stereotactic radiotherapy. 
  • Development and clinical evaluation of a three-dimensional cone-beam computed tomography estimation method using a deformation field map. 
  • Development and validation of a symptom index for advanced hepatobiliary and pancreatic cancers: the National Comprehensive Cancer Network Functional Assessment of Cancer Therapy (NCCN-FACT) Hepatobiliary-Pancreatic Symptom Index (NFHSI). 
  • Development and validation of insulin-like growth factor-1 score to assess hepatic reserve in hepatocellular carcinoma. 
  • Diagnosis of metastatic malignant melanoma by fine needle aspiration biopsy: a clinical and pathologic correlation of 298 cases. 
  • Diagnostic approach to hepatic hemangiomas. 
  • Diagnostic per-patient accuracy of an abbreviated hepatobiliary phase gadoxetic acid-enhanced MRI for hepatocellular carcinoma surveillance. 
  • Diaphragmatic hernia after hepatic resection: case series at a single Western institution. 
  • Differences in Liver Imaging and Reporting Data System Categorization Between MRI and CT. 
  • Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell lines. 
  • Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways. 
  • Digital tomosynthesis for respiratory gated liver treatment: clinical feasibility for daily image guidance. 
  • Digital tomosynthesis with an on-board kilovoltage imaging device. 
  • Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. 
  • Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease. 
  • Do surgical clips interfere with radiofrequency thermal ablation? 
  • Does the presence of coronary artery disease impact perioperative outcomes following partial hepatectomy? 
  • Downstaging of hepatocellular carcinoma and liver metastases from colorectal cancer by selective intra-arterial chemotherapy. 
  • Dual-Energy Multidetector Computed Tomography With Iodine Quantification in the Evaluation of Portal Vein Thrombosis: Is It Possible to Discard the Unenhanced Phase? 
  • Dual-Source Single-Energy Multidetector CT Used to Obtain Multiple Radiation Exposure Levels within the Same Patient: Phantom Development and Clinical Validation. 
  • Dual-energy MDCT in hypervascular liver tumors: effect of body size on selection of the optimal monochromatic energy level. 
  • Dual-phase 3D MDCT angiography for evaluation of the liver before hepatic resection. 
  • Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis. 
  • E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma. 
  • EF1A1-actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells. 
  • EUS-guided fine needle aspiration of the liver: indications, yield, and safety based on an international survey of 167 cases. 
  • Effect of Radiation Dose Reduction and Reconstruction Algorithm on Image Noise, Contrast, Resolution, and Detectability of Subtle Hypoattenuating Liver Lesions at Multidetector CT: Filtered Back Projection versus a Commercial Model-based Iterative Reconstruction Algorithm. 
  • Effect of a Noise-Optimized Second-Generation Monoenergetic Algorithm on Image Noise and Conspicuity of Hypervascular Liver Tumors: An In Vitro and In Vivo Study. 
  • Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: case-control study. 
  • Effect of exposure to light-at-night on life span and spontaneous carcinogenesis in female CBA mice. 
  • Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply. 
  • Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. II. Effect of serum and insulin. 
  • Effect of growth conditions on the ornithine decarboxylase activity of rat hepatoma cells. 
  • Effect of radiologists' experience with an adaptive statistical iterative reconstruction algorithm on detection of hypervascular liver lesions and perception of image quality. 
  • Effect of rapamycin alone and in combination with antiangiogenesis therapy in an orthotopic model of human pancreatic cancer. 
  • Effective pelvic symptom control using initial chemoradiation without colostomy in metastatic rectal cancer. 
  • Effectiveness of Transarterial Embolization of Hepatocellular Carcinoma as a Bridge to Transplantation. 
  • Effects of neoplasms on inflammation: depression of macrophage accumulation after tumor implantation. 
  • Efficacy of bevacizumab plus erlotinib for advanced hepatocellular carcinoma and predictors of outcome: final results of a phase II trial. 
  • Electrophoretic analysis of four high molecular weight sialoglycoproteins produced by metastatic human colon carcinoma cells. 
  • Endolymphatic immunotherapy in inoperable hepatocellular carcinoma. 
  • Endometriosis of the liver containing mullerian adenosarcoma: case report. 
  • Endoscopic palliation of a biliocutaneous fistula with expandable metal stents. 
  • Epidermal growth factor receptor expression and gene copy number in conventional hepatocellular carcinoma. 
  • Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma. 
  • Epithelial-mesenchymal transitions and hepatocarcinogenesis. 
  • Estimating Tumor Growth Rates In Vivo. 
  • Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells. 
  • Evaluation of a simpler technique for in-vivo labelling of red blood cells with 99mTc. 
  • Evaluation of hepatocellular carcinoma size using two-dimensional and volumetric analysis: effect on liver transplantation eligibility. 
  • Evaluation of the liver for metastatic disease. 
  • Examining reoperation and readmission after hepatic surgery. 
  • Excess mortality on the liver transplant waiting list: unintended policy consequences and Model for End-Stage Liver Disease (MELD) inflation. 
  • Experience with more than 500 minimally invasive hepatic procedures. 
  • Expression of cell adhesion molecule CD44 in primary tumors of the liver: an immunohistochemical study. 
  • Fine needle aspiration biopsy of the liver. 
  • Fine-needle aspiration of choroidal melanoma metastatic to the liver. 
  • Focal fatty infiltration: a cause of nontumorous defects in the left hepatic lobe during CT arterial portography. 
  • Focal hepatic lesions: detection by dynamic and delayed computed tomography versus short TE/TR spin echo and fast field echo magnetic resonance imaging. 
  • Focal intrahepatic extramedullary hematopoiesis mimicking neoplasm. 
  • Focal lesions in cirrhotic liver: what else beyond hepatocellular carcinoma? 
  • Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history. 
  • Focal nodular hyperplasia: typical and atypical MRI findings with emphasis on the use of contrast media. 
  • Fotemustine (S 10036) in the intra-arterial treatment of liver metastasis from malignant melanoma. A phase II Study. 
  • Four-dimensional image-based treatment planning: Target volume segmentation and dose calculation in the presence of respiratory motion. 
  • Four-dimensional magnetic resonance imaging using axial body area as respiratory surrogate: initial patient results. 
  • Frequency and predictors of de novo hepatocellular carcinoma in patients awaiting orthotopic liver transplantation during the model for end-stage liver disease era. 
  • Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis. 
  • Functional paragangliomas presenting as primary liver tumors. 
  • Gadobenate dimeglumine-enhanced magnetic resonance imaging of primary leiomyoma of the liver. 
  • Gastric adenocarcinoma: CT versus surgical staging. 
  • Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction. 
  • Giant pedunculated hemangioma of the liver. 
  • Glycogen storage disease type III-hepatocellular carcinoma a long-term complication? 
  • Glycogen storage disease types I and II: treatment updates. 
  • Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. 
  • Helical CT for detecting focal liver lesions in patients with breast carcinoma: comparison of noncontrast phase, hepatic arterial phase, and portal venous phase. 
  • Hepatic abscess with biliary communication following transarterial chemoembolization of hepatocellular carcinoma. 
  • Hepatic adenoma and focal nodular hyperplasia. 
  • Hepatic adenoma: MR appearance mimicking focal nodular hyperplasia. 
  • Hepatic adenoma: MR characteristics and correlation with pathologic findings. 
  • Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints. 
  • Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481). 
  • Hepatic complications of obesity. 
  • Hepatic dynamic sequential CT: section enhancement profiles with a bolus of ionic and nonionic contrast agents. 
  • Hepatic focal nodular hyperplasia in infant antenatally exposed to steroids. 
  • Hepatic hemangiomas vs metastases: MR differentiation at 1.5 T. 
  • Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium. 
  • Hepatic imaging characteristics predict overall survival in hepatocellular carcinoma. 
  • Hepatic metastasis from neuroblastoma. 
  • Hepatic parenchymal enhancement during triple-phase helical CT: can it be used to predict which patients with breast cancer will develop hepatic metastases? 
  • Hepatic resection for hepatocellular carcinoma: do contemporary morbidity and mortality rates demand a transition to ablation as first-line treatment? 
  • Hepatic resection for metastatic gastrointestinal stromal tumors in the tyrosine kinase inhibitor era. 
  • Hepatic tumors: comparison of CT during arterial portography, delayed CT, and MR imaging for preoperative evaluation. 
  • Hepatic tumors: region-of-interest versus volumetric analysis for quantification of attenuation at CT. 
  • Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. 
  • Hepatitis C. 
  • Hepatobiliary cystadenoma with mesenchymal stroma. 
  • Hepatocellular adenoma among adult survivors of childhood and young adult cancer. 
  • Hepatocellular carcinoma arising from ectopic liver tissue in the pancreas. 
  • Hepatocellular carcinoma in chronic hepatitis C in the absence of advanced fibrosis or cirrhosis. 
  • Hepatocellular carcinoma in glycogen storage disease type Ia: a case series. 
  • Hepatocellular carcinoma in patients with cirrhosis: qualitative comparison of gadobenate dimeglumine-enhanced MR imaging and multiphasic 64-section CT. 
  • Hepatocellular carcinoma lesion characterization: single-institution clinical performance review of multiphase gadolinium-enhanced MR imaging--comparison to prior same-center results after MR systems improvements. 
  • Hepatocellular carcinoma occurring in a patient with Crohn's disease treated with both azathioprine and infliximab. 
  • Hepatocellular carcinoma with intracavitary cardiac involvement: a case report and review of the literature. 
  • Hepatosplenic T-Cell Lymphoma: A Clinicopathologic Review With an Emphasis on Diagnostic Differentiation From Other T-Cell/Natural Killer-Cell Neoplasms. 
  • Hepatosplenic T-cell lymphoma: an unusual case of a gamma delta T-cell lymphoma with a blast-like terminal transformation. 
  • High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer. 
  • Human mesenchymal stem cell and epithelial hepatic carcinoma cell lines in admixture: concurrent stimulation of cancer-associated fibroblasts and epithelial-to-mesenchymal transition markers. 
  • Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. 
  • Human xenograft-nude mouse model of adoptive immunotherapy with human melanoma-specific cytotoxic T-cells. 
  • Hypervascular liver tumors: low tube voltage, high tube current multi-detector row CT for enhanced detection--phantom study. 
  • Hypervascular liver tumors: low tube voltage, high tube current multidetector CT during late hepatic arterial phase for detection--initial clinical experience. 
  • I-CLIP: improved stratification of advanced hepatocellular carcinoma patients by integrating plasma IGF-1 into CLIP score. 
  • Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers. 
  • Identification of liver cancer-specific aptamers using whole live cells. 
  • Imaging in Patients with Cirrhosis: Current Evidence. 
  • Imaging in the preoperative evaluation of adult liver-transplant candidates: goals, merits of various procedures, and recommendations. 
  • Imaging of patients with potentially resectable hepatic neoplasms. 
  • Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA. 
  • Impact of Pretransplant Bridging Locoregional Therapy for Patients With Hepatocellular Carcinoma Within Milan Criteria Undergoing Liver Transplantation: Analysis of 3601 Patients From the US Multicenter HCC Transplant Consortium. 
  • Impact of collimator leaf width and treatment technique on stereotactic radiosurgery and radiotherapy plans for intra- and extracranial lesions. 
  • Impact of liver-directed therapy in colorectal cancer liver metastases. 
  • Impact of simultaneous diaphragm resection during hepatectomy for treatment of metastatic colorectal cancer. 
  • Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein. 
  • Improved liver lesion conspicuity by increasing the flip angle during hepatocyte phase MR imaging. 
  • Improved time to progression for transarterial chemoembolization compared with transarterial embolization for patients with unresectable hepatocellular carcinoma. 
  • In vivo guidance and assessment of liver radio-frequency ablation with acoustic radiation force elastography. 
  • In vivo selection of tumor-targeting RNA motifs. 
  • In vivo visualization of abdominal malignancies with acoustic radiation force elastography. 
  • Increased expression of sialyl-dimeric LeX antigen in liver metastases of human colorectal carcinoma. 
  • Increased ubiquitin immunoreactivity in hepatocellular carcinomas and precancerous lesions of the liver. 
  • Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells. 
  • Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes. 
  • Inhibition of the growth of human melanoma metastases in nude mice by melanoma-specific murine monoclonal antibody. 
  • Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial. 
  • Intrahepatic cholangiocarcinoma: new insights in pathology. 
  • Intrahepatic landscape of regulatory T-cell subsets in chronically HCV-infected patients with cirrhosis and HCC. 
  • Intrahepatic mitomycin C as a salvage treatment for patients with hepatic metastases from colorectal carcinoma. 
  • Intrahepatic tumor recurrence after partial hepatectomy: value of percutaneous radiofrequency ablation. 
  • Intraindividual comparison of gadoxetate disodium-enhanced MR imaging and 64-section multidetector CT in the Detection of hepatocellular carcinoma in patients with cirrhosis. 
  • Intrathoracic metastasis from an extrathoracic malignancy: a radiographic approach to patient evaluation. 
  • Investigation of sagittal image acquisition for 4D-MRI with body area as respiratory surrogate. 
  • Is diaphragm motion a good surrogate for liver tumor motion? 
  • Is follow-up CT imaging of the chest and abdomen necessary after preoperative neoadjuvant therapy in rectal cancer patients without evidence of metastatic disease at diagnosis? 
  • Is selective internal radioembolization safe and effective for patients with inoperable hepatocellular carcinoma and venous thrombosis? 
  • Is there a role for simultaneous hepatic and colorectal resections? A contemporary view from NSQIP. 
  • Isolation of a transplantable cell line induced by the MC29 avian leukosis virus. 
  • Iterative reconstruction algorithm for abdominal multidetector CT at different tube voltages: assessment of diagnostic accuracy, image quality, and radiation dose in a phantom study. 
  • Kinetic differences in the induction of interferon stimulated genes by interferon-α and interleukin 28B are altered by infection with hepatitis C virus. 
  • Laparoscopic liver surgery: a synopsis. 
  • Laparoscopic staging for hepatobiliary carcinoma. 
  • Laparoscopic versus open resection of colorectal liver metastasis. 
  • Left hepatic trisectionectomy for hepatobiliary malignancy: results and an appraisal of its current role. 
  • Lipiodol: a potential direct surrogate for cone-beam computed tomography image guidance in radiotherapy of liver tumor. 
  • Liver MR imaging: comparison of respiratory triggered fast spin echo with T2-weighted spin-echo and inversion recovery. 
  • Liver and abdominal screening in patients with cancer: CT versus MR imaging. 
  • Liver and hepatic duct cancer. 
  • Liver and prostate adenocarcinoma: an "estrogen-free" environment? 
  • Liver imaging with multidetector helical computed tomography. 
  • Liver metastases from breast cancer: long-term survival after curative resection. 
  • Liver renewal: detecting misrepair and optimizing regeneration. 
  • Liver transplantation for glycogen storage disease type Ia. 
  • Liver transplantation for the treatment of hepatocellular carcinoma. 
  • Liver transplantation versus liver resection in the treatment of hepatocellular carcinoma: a meta-analysis of observational studies. 
  • Liver transplantation. 
  • Living and deceased donor liver transplantation for unresectable hepatoblastoma at a single center. 
  • Living donor liver transplantation versus deceased donor liver transplantation for hepatocellular carcinoma: a meta-analysis. 
  • Local radiotherapy with or without transcatheter arterial chemoembolization for patients with unresectable hepatocellular carcinoma. 
  • Long-term survival after spontaneous rupture of a malignant rhabdoid tumor of the liver. 
  • Loss of KAI1 expression in the progression of colorectal cancer. 
  • Low-tube-voltage, high-tube-current multidetector abdominal CT: improved image quality and decreased radiation dose with adaptive statistical iterative reconstruction algorithm--initial clinical experience. 
  • MCA106 fibrosarcoma cells transduced with granulocyte/macrophage colony-stimulating factor are not superior to the wild-type cells in suppressing the growth of hepatic metastases. 
  • MDCT necrosis quantification in the assessment of hepatocellular carcinoma response to yttrium 90 radioembolization therapy: comparison of two-dimensional and volumetric techniques. 
  • MR of focal liver lesions: comparison of breath-hold and non-breath-hold hybrid RARE and conventional spin-echo T2-weighted pulse sequences. 
  • Macrophage migratory dysfunction in cancer. A mechanism for subversion of surveillance. 
  • Magnetic resonance imaging of the cirrhotic liver in the era of gadoxetic acid. 
  • Major liver resection in elderly patients: a multi-institutional analysis. 
  • Malignant biliary obstruction: efficacy of thin-section dynamic CT in determining resectability. 
  • Mechanisms of disease progression in nonalcoholic fatty liver disease. 
  • Menorrhagia in patients with type I glycogen storage disease. 
  • Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer. 
  • Metastases of colorectal cancer to the liver and peritoneum: comparison of surgical paradigms. 
  • Metastatic adenocarcinomas of unknown primary site. Prognostic variables and treatment results. 
  • Metastatic colorectal cancer cells from patients previously treated with chemotherapy are sensitive to T-cell killing mediated by CEA/CD3-bispecific T-cell-engaging BiTE antibody. 
  • Metastatic colorectal cancer: survival comparison of hepatic resection versus cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. 
  • Metastatic potential of colon carcinoma. Expression of ABO/Lewis-related antigens. 
  • Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines. 
  • Minimally invasive liver resection for metastatic colorectal cancer: a multi-institutional, international report of safety, feasibility, and early outcomes. 
  • Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1. 
  • Modified cisplatin/interferon α-2b/doxorubicin/5-fluorouracil (PIAF) chemotherapy in patients with no hepatitis or cirrhosis is associated with improved response rate, resectability, and survival of initially unresectable hepatocellular carcinoma. 
  • Multiagent chemotherapy for isolated colorectal liver metastases: a single-centered retrospective study. 
  • Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose? 
  • Multiple endocrine neoplasia type 1 manifesting with chronic and persistent diarrhea. 
  • Mutation of p53 gene in hepatocellular carcinoma cell lines with HBX DNA. 
  • NAFLD, NASH and liver cancer. 
  • Negative biopsies, deadly disease: metastatic angiosarcoma. 
  • Nitric oxide-dependent osteopontin expression induces metastatic behavior in HepG2 cells. 
  • Nodular regenerative hyperplasia in partial hepatectomy specimens. 
  • Non-Hodgkin lymphoma presenting with obstructive jaundice. 
  • Non-genetic risk factors and predicting efficacy for docetaxel--drug-induced liver injury among metastatic breast cancer patients. 
  • Non-hepatocellular carcinoma spinal metastases. 
  • Nonalcoholic Fatty Liver Disease and the Gut Microbiome. 
  • Not by blood alone: diagnosis of hemangiomas by fine-needle aspiration. 
  • Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. 
  • On confirmation bias in imaging research. 
  • Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma. 
  • Open-label prospective study of the safety and efficacy of glass-based yttrium 90 radioembolization for infiltrative hepatocellular carcinoma with portal vein thrombosis. 
  • Opportunities for targeted therapies in hepatocellular carcinoma. 
  • Optimal timing and diagnostic adequacy of hepatocyte phase imaging with gadoxetate-enhanced liver MRI. 
  • Osteopontin regulates epithelial mesenchymal transition-associated growth of hepatocellular cancer in a mouse xenograft model. 
  • Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. 
  • Outcomes associated with cytoreductive surgery and intraperitoneal hyperthermic chemotherapy in colorectal cancer patients with peritoneal surface disease and hepatic metastases. 
  • Overall survival or other clinical benefits from adjuvant selective intraarterial chemotherapy in patients undergoing curative liver resection for metastatic colorectal tumor. 
  • Overview of stereotactic body radiotherapy and the nursing role. 
  • Oxygen flux analysis to understand the biological function of sirtuins. 
  • PGC-1beta in the regulation of hepatic glucose and energy metabolism. 
  • Painful palmar and plantar erythema associated with hepatic artery infusion of 5-fluoro-2'deoxyuridine. 
  • Paracrine Hedgehog signaling drives metabolic changes in hepatocellular carcinoma. 
  • Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. 
  • Pathology and imaging of hepatocellular neoplasms: are findings from Asian populations applicable to non-Asian groups? 
  • Patient and tumor characteristics predictive of an elevated hepatopulmonary shunt fraction before radioembolization of hepatic tumors. 
  • Patient expectations of benefit from phase I clinical trials: linguistic considerations in diagnosing a therapeutic misconception. 
  • Percutaneous transhepatic choledochocholedochostomy in the management of the postoperative patient. 
  • Perioperative and oncologic outcomes of minimally invasive liver resection for colorectal metastases: A case-control study of 130 patients. 
  • Peritoneal surface disease from colorectal cancer: comparison with the hepatic metastases surgical paradigm in optimally resected patients. 
  • Peritoneal surface disease with synchronous hepatic involvement treated with Cytoreductive Surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). 
  • Pharmacokinetics of combined gene therapy expressing constitutive human GM-CSF and hyperthermia-regulated human IL-12. 
  • Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinoma. 
  • Phase II trial of edatrexate in patients with advanced pancreatic adenocarcinoma. 
  • Phase II trial of the combination of bevacizumab and erlotinib in patients who have advanced hepatocellular carcinoma. 
  • Phase II trials of dolastatin-10 in advanced pancreaticobiliary cancers. 
  • Physician-assisted suicide and advance directives concerning life support. 
  • Pilot Evaluation of Angiogenesis Signaling Factor Response after Transcatheter Arterial Embolization for Hepatocellular Carcinoma. 
  • Plasma miRNAs as early biomarkers for detecting hepatocellular carcinoma. 
  • Predictive algorithms: uses and limitations. 
  • Preoperative chemoradiation for adenocarcinoma of the pancreas: excessive toxicity of prophylactic hepatic irradiation. 
  • Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the pancreatic head. 
  • Preoperative localization of focal liver lesions to specific liver segments: utility of CT during arterial portography. 
  • Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer. 
  • Primary carcinoma of the upper urinary tract. Effect of primary and secondary therapy on survival. 
  • Primary high-grade neuroendocrine carcinoma emerging from an adenomatous polyp in the setting of familial adenomatous polyposis. 
  • Primary leiomyoma of the liver. 
  • Proceed with caution: liver transplantation for metastatic neuroendocrine tumors. 
  • Prognostic factors in the initial response to therapy by patients with advanced breast cancer. 
  • Prognostic indicators and treatment outcome in 94 cases of fibrolamellar hepatocellular carcinoma. 
  • Prognostic significance of glutamine synthetase expression in unifocal advanced hepatocellular carcinoma. 
  • Prognostic significance of plasma scatter factor/hepatocyte growth factor levels in patients with metastatic hormone- refractory prostate cancer: results from cancer and leukemia group B 150005/9480. 
  • Prognostic variables in patients with hepatic metastases from colorectal cancer. Importance of medical assessment of liver involvement. 
  • Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3' UTR structures. 
  • RNA stability regulates differential expression of the metastasis protein, osteopontin, in hepatocellular cancer. 
  • Radiation-induced liver disease after three-dimensional conformal radiotherapy for patients with hepatocellular carcinoma: dosimetric analysis and implication. 
  • Radiofrequency ablation of liver tumors: influence of technique and tumor size. 
  • Radiological evaluation of metastases to the liver: The Emory experience. 
  • Randomized trial of hepatic arterial floxuridine, mitomycin, and carmustine versus floxuridine alone in previously treated patients with liver metastases from colorectal cancer. 
  • Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed. 
  • Rapid degradation of puromycyl peptides in hepatoma cells and reticulocytes. 
  • Rates of surveillance and management of hepatocellular carcinoma in patients evaluated at a liver transplant center. 
  • Rationale of technical requirements for NRG-BR001: The first NCI-sponsored trial of SBRT for the treatment of multiple metastases. 
  • Reassessing hepatocellular carcinoma staging in a changing patient population. 
  • Recurrence of hepatocellular cancer after resection: patterns, treatments, and prognosis. 
  • Recurrent Burkitt's lymphoma mimicking toxic veno-occlusive disease of the liver. 
  • Recurrent tumor after resection of hepatic metastases from colorectal carcinoma: location and time of discovery as determined by CT. 
  • Resection of hepatocellular adenoma in patients with glycogen storage disease type Ia. 
  • Resection of hepatocellular carcinoma with macroscopic vascular invasion. 
  • Resection of hepatocellular carcinoma without cirrhosis. 
  • Resection of large hepatocellular carcinoma (≥10 cm): a unique western perspective. 
  • Resection of noncolorectal nonneuroendocrine liver metastases: a comparative analysis. 
  • Resection or transplant-listing for solitary hepatitis C-associated hepatocellular carcinoma: an intention-to-treat analysis. 
  • Retrospective clinicopathologic correlation of gross tumor size of hepatocellular carcinoma: implications for stereotactic body radiotherapy. 
  • Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus. 
  • Role of computed tomography in screening for hepatocellular carcinoma in patients with cirrhosis. 
  • S-nitrosylation of the Mitochondrial Chaperone TRAP1 Sensitizes Hepatocellular Carcinoma Cells to Inhibitors of Succinate Dehydrogenase. 
  • Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). 
  • Should hepatic resections be performed at high-volume referral centers? 
  • Simultaneous resections of colorectal cancer and synchronous liver metastases: a multi-institutional analysis. 
  • Sofosbuvir and ribavirin for treatment of compensated recurrent hepatitis C virus infection after liver transplantation. 
  • Sorting multiple classes in multi-dimensional ROC analysis: parametric and nonparametric approaches. 
  • Spindle-cell lesions of the liver: diagnosis by fine-needle aspiration biopsy. 
  • Squamous-cell carcinoma, Kaposi's sarcoma and Burkitt's lymphoma are consequences of impaired immune surveillance of ubiquitous viruses in acquired immune deficiency syndrome, allograft recipients and tropical African patients. 
  • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. 
  • Stemming the tide of hepatitis B virus related hepatocellular carcinoma? 
  • Subcentimeter hypervascular nodule with typical imaging findings of hepatocellular carcinoma in patients with history of hepatocellular carcinoma: natural course on serial gadoxetic acid-enhanced MRI and diffusion-weighted imaging. 
  • Successful treatment of immune thrombocytopenic purpura with anti-D antibody following a cadaveric liver transplant for hepatoblastoma. 
  • Superparamagnetic iron oxide particles (SH U 555 A): evaluation of efficacy in three doses for hepatic MR imaging. 
  • Surgery or ablative radiotherapy for breast cancer oligometastases. 
  • Surgical clearance for the patient with chronic liver disease. 
  • Surgical resection for small hepatocellular carcinoma. 
  • Synchronous colorectal liver metastases: is it time to reconsider traditional paradigms of management? 
  • Synchronous colorectal liver metastases: the "surgeon as oncologist" perspective. 
  • T2-Weighted Liver MRI Using the MultiVane Technique at 3T: Comparison with Conventional T2-Weighted MRI. 
  • TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma. 
  • Targeting vascular endothelial growth factor in advanced carcinoid tumor: a random assignment phase II study of depot octreotide with bevacizumab and pegylated interferon alpha-2b. 
  • Technique for MR imaging of the liver. 
  • Thalidomide in the treatment of patients with hepatocellular carcinoma: a phase II trial. 
  • The acute promyelocytic leukemia PML-RAR alpha protein induces hepatic preneoplastic and neoplastic lesions in transgenic mice. 
  • The addition of erlotinib to gemcitabine and cisplatin does not appear to improve median survival in metastatic pancreatic cancer. 
  • The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer. 
  • The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1. 
  • The association of family history of liver cancer with hepatocellular carcinoma: a case-control study in the United States. 
  • The diagnostic accuracy/efficacy of MRI in differentiating hepatic hemangiomas from metastatic colorectal/breast carcinoma: a multiple reader ROC analysis using a jackknife technique. 
  • The effect of prior androgen synthesis inhibition on outcomes of subsequent therapy with docetaxel in patients with metastatic castrate-resistant prostate cancer: results from a retrospective analysis of a randomized phase 3 clinical trial (CALGB 90401) (Alliance). 
  • The effect of protein nutrition on host and tumor metabolism. 
  • The effectiveness of locoregional therapies versus supportive care in maintaining survival within the Milan criteria in patients with hepatocellular carcinoma. 
  • The efficacy of anti-PD-1 agents in acral and mucosal melanoma. 
  • The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens. 
  • The extended Toronto criteria for liver transplantation in patients with hepatocellular carcinoma: A prospective validation study. 
  • The frequency and significance of small (less than or equal to 15 mm) hepatic lesions detected by CT. 
  • The impact of respiratory motion and treatment technique on stereotactic body radiation therapy for liver cancer. 
  • The natural history of hepatitis C viral infection. 
  • The role of F-18 FDG positron emission tomography in preoperative assessment of the liver in patients being considered for curative resection of hepatic metastases from colorectal cancer. 
  • The role of Hedgehog signaling in fibrogenic liver repair. 
  • The role of hepatic resection in the treatment of hepatocellular cancer. 
  • The subcellular localization of syntaxin 17 varies among different cell types and is altered in some malignant cells. 
  • The use of ultrasound to enhance the diagnostic utility of the equivocal liver scintigraph. 
  • The utility of micro-CT and MRI in the assessment of longitudinal growth of liver metastases in a preclinical model of colon carcinoma. 
  • Threshold for Enhancement in Treated Hepatocellular Carcinoma on MDCT: Effect on Necrosis Quantification. 
  • Timing Is Everything. 
  • Timing of multimodality therapy for resectable synchronous colorectal liver metastases: a retrospective multi-institutional analysis. 
  • To ablate or not to ablate?: that is the question. 
  • Transforming growth factor-beta receptors and mannose 6-phosphate/insulin-like growth factor-II receptor expression in human hepatocellular carcinoma. 
  • Transplant versus resection for the management of hepatocellular carcinoma meeting Milan Criteria in the MELD exception era at a single institution in a UNOS region with short wait times. 
  • Transplanted carcinoma in an immunosuppressed patient. 
  • Treatment of advanced colorectal cancer. 
  • Treatment of giant hemangiomas of the liver by enucleation. 
  • Treatment of human melanoma hepatic metastases in nude mice with human cytotoxic T lymphocytes. 
  • Treatment of unresectable primary liver cancer with intrahepatic fluorodeoxyuridine and mitomycin C through an implantable pump. 
  • Underlying potential: cellular and molecular determinants of adult liver repair. 
  • Unknown primary tumors metastatic to liver. 
  • Unresectable hepatocellular carcinoma treated with radiotherapy and/or chemoembolization. 
  • Up-regulation of Hedgehog pathway is associated with cellular permissiveness for hepatitis C virus replication. 
  • Use of bioluminescence imaging to detect enhanced hepatic and systemic tumor growth following partial hepatectomy in mice. 
  • Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice. 
  • V-CLIP: Integrating plasma vascular endothelial growth factor into a new scoring system to stratify patients with advanced hepatocellular carcinoma for clinical trials. 
  • Vector-related tumorigenesis not found in ornithine transcarbamylase-deficient mice. 
  • Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma. 
  • Who decides? Living donor liver transplantation for advanced hepatocellular carcinoma. 
  • With proper imaging technique, is it still necessary to obtain images of the liver before administering contrast material in patients with known tumors who can have hypervascular liver metastases? 
  • Without victory there is no survival: transarterial lipiodol chemoembolization and hepatocellular carcinoma. 
  • [Comparison and analysis of clinicopathology of lung cancer between 1980s and 1990s in the Shenyang area (1,224 cases)]. 
  • [Intraportal injection of specific monoclonal antibody in nude mice with liver metastasis]. 
  • [Malignant melanoma: hepatic intra-arterial chemotherapy]. 
  • c-myc-Dependent hepatoma cell apoptosis results from oxidative stress and not a deficiency of growth factors. 
  • p53 does not repress hypoxia-induced transcription of the vascular endothelial growth factor gene. 
• 

  Keywords of People

  • Abbruzzese, James, Charles Johnson, M.D. Professor of Medicine, Medicine, Medical Oncology
  • Buckley, Anne Frances, Assistant Professor of Pathology, Pathology
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Colsher, James George, Adjunct Assistant Professor in the Department of Radiology, Radiology, Nuclear Medicine
  • Hirschey, Matthew, Associate Professor in Medicine, Pharmacology & Cancer Biology
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Jowell, Paul Simon, Professor of Medicine, Medicine, Gastroenterology
  • MacFall, James R., Adjunct Professor in the Department of Radiology, Radiology
  • Sosa, Julie Ann, Professor of Surgery, Medicine, Medical Oncology
  • Sullivan, Daniel Carl, Professor Emeritus of Radiology, Radiology
  • Uronis, Hope Elizabeth, Associate Professor of Medicine, Medicine, Medical Oncology