Liver Regeneration

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  Subject Areas on Research

  • A20 modulates lipid metabolism and energy production to promote liver regeneration. 
  • A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism. 
  • Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans. 
  • Aging reduces liver resiliency by dysregulating Hedgehog signaling. 
  • Alcohol and cytokine-inducible transcription factors. 
  • Alpha 1-adrenergic effects and liver regeneration. 
  • Altered levels of prothymosin immunoreactive peptide, a growth-related gene product, during liver regeneration after chronic ethanol feeding. 
  • Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. 
  • Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration. 
  • Cell death-stimulated cell proliferation: a tissue regeneration mechanism usurped by tumors during radiotherapy. 
  • Characterization of 57 kDa statin as a true marker for growth arrest in tissue by its disappearance from regenerating liver. 
  • Chronic ethanol consumption disturbs G-protein expression and inhibits cyclic AMP-dependent signaling in regenerating rat liver. 
  • Cross circulation between children in hepatic coma and chimpanzees. Clinical, biochemical, and coagulation observations. 
  • Cytokine regulation of liver injury and repair. 
  • Cytokines and alcoholic liver disease. 
  • Differential expression of guanine nucleotide-binding proteins enhances cAMP synthesis in regenerating rat liver. 
  • Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo. 
  • Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology. 
  • Down-regulation of transforming growth factor beta receptor type I, II, and III during liver regeneration. 
  • Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice. 
  • Dysregulated activation of fetal liver programme in acute liver failure. 
  • Effect of actinomycin D on serum betalipoproteins of partially hepatectomized dogs. I. Proteins, lipids, triglycerides and cholesterol. 
  • Effect of actinomycin D on serum betalipoproteins of partially hepatectomized dogs. II - Phospholipids. 
  • Effect of actinomycin D on serum betalipoproteins of partially hepatectomized dogs. III - Fatty acid distribution. 
  • Effect of ethanol on polyamine synthesis during liver regeneration in rats. 
  • Effect of ethanol on tumor necrosis factor signaling during liver regeneration. 
  • Effects of chronic ethanol consumption on cytokine regulation of liver regeneration. 
  • Effects of liver growth factors on hepadnavirus replication in chronically infected duck hepatocytes. 
  • Effects of terlipressin versus splenectomy on liver regeneration after partial hepatectomy in rats: What we know so far? 
  • Epithelial-to-mesenchymal transitions in the liver. 
  • Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy. 
  • Ethanol inhibits liver regeneration in rats without reducing transcripts of key protooncogenes. 
  • Ethanol interferes with regeneration-associated changes in biotransforming enzymes: a potential mechanism underlying ethanol's carcinogenicity? 
  • Ethanol-associated alterations in the kinetics of putrescine uptake and metabolism by the regenerating liver. 
  • Evidence for and against epithelial-to-mesenchymal transition in the liver. 
  • Extended hepatectomy using the bipolar tissue sealer: an experimental model of small-for-size syndrome in pigs. 
  • Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers. 
  • Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy. 
  • Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis. 
  • Hedgehog regulates yes-associated protein 1 in regenerating mouse liver. 
  • Hedgehog signaling in the liver. 
  • Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice. 
  • Hematopoietic stem cells convert into liver cells within days without fusion. 
  • Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease. 
  • Hepatic regeneration is associated with preservation of microsomal glucuronidation. 
  • Hepatocellular expression of glucose-6-phosphatase is unaltered during hepatic regeneration. 
  • Hypoxia of the growing liver accelerates regeneration. 
  • Immunohistochemical characterization of the hepatic progenitor cell compartment in medaka (Oryzias latipes) following hepatic injury. 
  • Impact of steatosis on perioperative outcome following hepatic resection. 
  • Impaired liver regeneration in inducible nitric oxide synthasedeficient mice. 
  • Interleukin-15 increases hepatic regenerative activity. 
  • It is the function of regenerating liver parenchyma that explains the small for size syndrome. 
  • Keratinocyte growth factor--just another mitogen or the "Holy Grail" that regulates liver regeneration? 
  • Kupffer cell depletion abolishes induction of interleukin-10 and permits sustained overexpression of tumor necrosis factor alpha messenger RNA in the regenerating rat liver. 
  • Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy. 
  • Kupffer cell depletion by gadolinium chloride enhances liver regeneration after partial hepatectomy in rats. 
  • Less is more: salvageability as the new creed in surgery of colorectal liver metastatic disease. 
  • Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism? 
  • Liver hypoxia as a trigger to liver regeneration: No more than another piece of the puzzle. 
  • Liver regeneration 3: Regulation of signal transduction during liver regeneration. 
  • Liver regeneration in obese mice with fatty livers: does the impairment have relevance for other types of fatty liver disease? 
  • Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes. 
  • Liver regeneration. 
  • Liver renewal: detecting misrepair and optimizing regeneration. 
  • Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. 
  • Long-term ethanol consumption alters the hepatic response to the regenerative effects of tumor necrosis factor-alpha. 
  • Long-term follow-up of auxiliary liver transplantation for fulminant hepatic failure. 
  • Long-term mutagenicity studies with chloroform and dimethylnitrosamine in female lacI transgenic B6C3F1 mice. 
  • Mechanistic insights of rapid liver regeneration after associating liver partition and portal vein ligation for stage hepatectomy. 
  • Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure. 
  • Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy. 
  • Mystery of Liver Regeneration After Portal Flow Changes: The Inductive Way of Thinking May Give the Answers. 
  • Nodular regenerative hyperplasia in partial hepatectomy specimens. 
  • Non-alcoholic steatohepatitis pathogenesis: role of repair in regulating the disease progression. 
  • Nutrition, hormones, metabolism, and liver regeneration. 
  • Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease. 
  • Partial hepatectomy and bile duct ligation in rainbow trout (Oncorhynchus mykiss): histologic, immunohistochemical and enzyme histochemical characterization of hepatic regeneration and biliary hyperplasia. 
  • Pathology and imaging of hepatocellular neoplasms: are findings from Asian populations applicable to non-Asian groups? 
  • Prometheus revisited. 
  • Recent events in alcoholic liver disease V. effects of ethanol on liver regeneration. 
  • Regeneration of a transplanted liver after right hepatic lobectomy. 
  • Regenerative changes in C/EBP alpha and C/EBP beta expression modulate binding to the C/EBP site in the c-fos promoter. 
  • Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism. 
  • Roles of CCAAT/enhancer-binding proteins in regulation of liver regenerative growth. 
  • STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers. 
  • Selective changes in protein kinase C isoenzymes in rat liver nuclei during liver regeneration. 
  • Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration. 
  • Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells. 
  • Studies on the regulation and specificity of the DNA-untwisting enzyme. 
  • Supplemental putrescine reverses ethanol-associated inhibition of liver regeneration. 
  • TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice. 
  • Technical modifications and outcomes after Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) for primary liver malignancies: A systematic review. 
  • The diversity and plasticity of adult hepatic progenitor cells and their niche. 
  • The effect of chronic ethanol feeding on ornithine decarboxylase activity and liver regeneration. 
  • The effect of octreotide on hepatic regeneration in rats. 
  • The role of Hedgehog signaling in fibrogenic liver repair. 
  • The role of platelets on regenerating liver: Thoughts beyond parenchymal proliferation. 
  • Time course and mechanism of alterations in proton relaxation during liver regeneration in the rat. 
  • Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver. 
  • Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. 
  • Tumor necrosis factor-alpha modulates CCAAT/enhancer binding proteins-DNA binding activities and promotes hepatocyte-specific gene expression during liver regeneration. 
  • Underlying potential: cellular and molecular determinants of adult liver repair. 
  • Vascular interference: a blockade to tumor epithelial growth. 
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  Keywords of People

  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology