Lupus Erythematosus, Systemic

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  Subject Areas on Research

  • 60 kD Ro and nRNP A frequently initiate human lupus autoimmunity. 
  • A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells. 
  • A host protein (La) binds to a unique species of minus-sense leader RNA during replication of vesicular stomatitis virus. 
  • A national study of the complications of lupus in pregnancy. 
  • A novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLE. 
  • A proposed framework to standardize the neurocognitive assessment of patients with pediatric systemic lupus erythematosus. 
  • A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus. 
  • A serial study of splenic reticuloendothelial system Fc receptor functional activity in systemic lupus erythematosus. 
  • A simple enzyme-linked immunosorbent assay for antibodies to native DNA. 
  • Abnormalities in serum osteocalcin values in children with chronic rheumatic diseases. 
  • Acne agminata limited to the eyelids. 
  • African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity. 
  • Alemtuzumab induction and recurrence of glomerular disease after kidney transplantation. 
  • Altered toll-like receptor responsiveness underlies a dominant heritable defect in B cell tolerance in autoimmune New Zealand Black mice. 
  • An adolescent on peritoneal dialysis with acute encephalopathy. 
  • An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus. 
  • An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. 
  • An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. 
  • Analysis of a large pedigree with elliptocytosis, multiple lipomatosis, and biological false-positive serological test for syphilis. 
  • Analysis of autoantibodies to plasminogen in the serum of patients with rheumatoid arthritis. 
  • Annexin A5 anticoagulant activity in children with systemic lupus erythematosus and the association with antibodies to domain I of β2-glycoprotein I. 
  • Anti-DNA and autoantibodies. 
  • Anti-DNA antibodies in systemic lupus erythematosus. 
  • Anti-DNA antibodies in systemic lupus erythematosus: a case of mistaken identity? 
  • Anti-DNA antibodies--quintessential biomarkers of SLE. 
  • Anti-La antibodies. 
  • Anti-La antibody production by MRL-1pr/1pr mice. Analysis of fine specificity. 
  • Anti-Ro and anti-nRNP response in unaffected family members of SLE patients. 
  • Anti-Sm autoantibodies in MRL mice: analysis of precursor frequency. 
  • Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens. 
  • Antibodies to CD45 and other cell membrane antigens in systemic lupus erythematosus. 
  • Antibodies to DNA. A perspective. 
  • Antibodies to DNA: infection or genetics? 
  • Antibody responses to DNA in normal immunity and aberrant immunity. 
  • Antidouble stranded DNA antibody assays in systemic lupus erythematosus: correlations of longitudinal antibody measurements. 
  • Antinuclear antibodies in healthy people: the tip of autoimmunity's iceberg? 
  • Antinuclear antibodies in rheumatic disease: a proposal for a function-based classification. 
  • Antinuclear antibody testing - misunderstood or misbegotten? 
  • Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE). 
  • Antiphospholipid antibodies in patients without systemic lupus erythematosus: neuroradiologic findings. 
  • Antiphospholipid syndrome with catastrophic bleeding and recurrent ischemic strokes as initial presentation of systemic lupus erythematosus. 
  • Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus. 
  • Are autoantibodies the targets of B-cell-directed therapy? 
  • Association between the 7 S RNA and the lupus La protein varies among cell types. 
  • Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype. 
  • Association of Transition Readiness to Intentional Self-Regulation and Hopeful Future Expectations in Youth With Illness. 
  • Association of systemic lupus erythematosus with angiographically defined coronary artery disease: a retrospective cohort study. 
  • Autoantibodies and their idiotypes. 
  • Autoantibodies and their idiotypes. 
  • Autoantibodies and their significance. 
  • Autoantibodies before the clinical onset of systemic lupus erythematosus. 
  • Autoantibodies to DEK oncoprotein in human inflammatory disease. 
  • Autoimmunity: the nuclear arsenal of autoimmunity. 
  • Autoregulation of Tcr V region epitopes in autoimmune disease. 
  • Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature. 
  • B cell loss leading to remission in severe systemic lupus erythematosus. 
  • B cell-directed therapies for autoimmune disease and correlates of disease response and relapse. 
  • B lymphocytes and systemic lupus erythematosus. 
  • BAFF-ling autoantibodies. 
  • Basement membrane antibody with skin bullae. 
  • Beta-lactam antibiotic-induced pseudoporphyria. 
  • Breastfeeding in mothers with systemic lupus erythematosus. 
  • Bullous eruption of systemic lupus erythematosus. 
  • Bullous eruption of systemic lupus erythematosus. Dramatic response to dapsone therapy. 
  • CD19 hyperexpression augments Sle1-induced humoral autoimmunity but not clinical nephritis. 
  • CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States. 
  • Cancer risk in childhood-onset systemic lupus. 
  • Cardiac operations for North American children with rheumatic diseases: 1985-2005. 
  • Cellular targeting in autoimmunity. 
  • Characterization of antibodies to bacterial double-stranded DNA in the sera of normal human subjects. 
  • Characterization of human serum dipeptidyl peptidase IV (CD26) and analysis of its autoantibodies in patients with rheumatoid arthritis and other autoimmune diseases. 
  • Circulating immune complexes in dermatologic disease. 
  • Clinical criteria for systemic lupus erythematosus precede diagnosis, and associated autoantibodies are present before clinical symptoms. 
  • Clinical problem-solving. Taken out of context. 
  • Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or lupus-like disease. 
  • Comparing questionnaire-based methods to assess occupational silica exposure. 
  • Comparison of an enzyme immunoassay to an indirect fluorescent immunoassay for the detection of antinuclear antibodies. 
  • Comparison of breast cancer risk in women with and without systemic lupus erythematosus in a Medicare population. 
  • Comparison of survival among patients with connective tissue disease and cardiomyopathy (systemic sclerosis, systemic lupus erythematosus, and undifferentiated disease). 
  • Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2. 
  • Consensus treatment plans for induction therapy of newly diagnosed proliferative lupus nephritis in juvenile systemic lupus erythematosus. 
  • Constrictive pericarditis due to hydralazine-induced lupus erythematosus. 
  • Criteria for steroid-sparing ability of interventions in systemic lupus erythematosus: report of a consensus meeting. 
  • Crohn's disease and systemic lupus erythematosus. 
  • Cryptococcemia. 
  • Curiouser and curiouser: the role(s) of AID expression in self-tolerance. 
  • Cyclophosphamide for lupus during pregnancy. 
  • DNA as a marker of cell death in systemic lupus erythematosus. 
  • Decreased cochlear DNA receptor staining in MRL.MpJ-Fas(lpr) autoimmune mice with hearing loss. 
  • Decreased properdin activity in acute glomerulonephritis. 
  • Deep venous thrombosis and a circulating anticoagulant in systemic lupus erythematosus. 
  • Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. 
  • Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice. 
  • Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency. 
  • Deficient expression of antibodies specific for bacterial DNA by patients with systemic lupus erythematosus. 
  • Delays to Care in Pediatric Lupus Patients: Data From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. 
  • Depressive symptoms and associated factors in systemic lupus erythematosus. 
  • Detection of activated terminal complement (C5b-9) in cerebrospinal fluid from patients with central nervous system involvement of primary Sjogren's syndrome or systemic lupus erythematosus. 
  • Detection of complement in relation to disease. 
  • Development of autoantibodies before the clinical onset of systemic lupus erythematosus. 
  • Development of systemic lupus erythematosus following autologous bone marrow transplant for acute lymphocytic leukemia. 
  • Developments in the scientific understanding of lupus. 
  • Differences by race, sex and age in the clinical and immunologic features of recently diagnosed systemic lupus erythematosus patients in the southeastern United States. 
  • Disease activity, proteinuria, and vitamin D status in children with systemic lupus erythematosus and juvenile dermatomyositis. 
  • Disseminated histoplasmosis in systemic lupus erythematosus: case report and review of the literature. 
  • Disseminated infection with rapidly growing mycobacteria. 
  • Dyslipoproteinemia and premature atherosclerosis in pediatric systemic lupus erythematosus. 
  • Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry. 
  • Early risk factors for pregnancy loss in lupus. 
  • Effects of infertility, pregnancy loss, and patient concerns on family size of women with rheumatoid arthritis and systemic lupus erythematosus. 
  • Effects of inherited thrombophilic mutations in an adolescent with antiphospholipid syndrome and systemic lupus erythematosus. 
  • Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus. 
  • Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double-Blind, Placebo-Controlled Trials. 
  • Electron microscopic virus-like material in systemic lupus erythematosus: with preliminary immunologic observations on presence of measles antigen. 
  • Elevated C-reactive protein and self-reported disease activity in systemic lupus erythematosus. 
  • Erosive diseases of the vulva. 
  • Erythrocyte sedimentation rate and C-reactive protein levels are poorly correlated with clinical measures of disease activity in rheumatoid arthritis, systemic lupus erythematosus and osteoarthritis patients. 
  • Etanercept-induced lupus-like syndrome in a patient with rheumatoid arthritis. 
  • Examination of Hydroxychloroquine Use and Hemolytic Anemia in G6PDH-Deficient Patients. 
  • Expression of IgM and IgG autoantibodies in pediatric and adult systemic lupus erythematosus. 
  • Expression of autoantibodies to recombinant (U1) RNP-associated 70K antigen in systemic lupus erythematosus. 
  • Expression of high mobility group protein 1 in the sera of patients and mice with systemic lupus erythematosus. 
  • Fatal lupus pleuritis presenting in pregnancy. A case report. 
  • Fc-receptor dysfunction in lupus. 
  • Fc-receptor dysfunction in lupus. 
  • Feasibility of renal transplantation in systemic lupus erythematosus. 
  • Fulminant myopericarditis from phenytoin-induced systemic lupus erythematosus. 
  • Functional alterations of macrophages in autoimmune MRL-lpr/lpr mice. 
  • Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. 
  • Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. 
  • Gestational weight gain in women with systemic lupus erythematosus. 
  • Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: a possible gene-environment interaction for autoimmunity. 
  • Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus. 
  • HMGB1: a dangerous player in lupus pathogenesis. 
  • Heavy and light chain utilization in autoantibodies of elderly patients with systemic lupus erythematosus. 
  • Hereditary C2 deficiency associated with cutaneous lupus erythematosus: clinical, laboratory, and genetic studies. 
  • Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control study. 
  • Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus. 
  • Human T lymphocyte antigens as defined by monoclonal antibodies. 
  • Human immunoglobulin therapy for preeclampsia associated with lupus anticoagulant and anticardiolipin antibody. 
  • Humoral autoimmunity to basement membrane antigens is regulated in C57BL/6 and MRL/MpJ mice transgenic for anti-laminin Ig receptors. 
  • Hybridoma SLE autoantibodies: insights for the pathogenesis of autoimmune disease. 
  • Hydroxychloroquine in lupus pregnancy. 
  • Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus. 
  • Hydroxychloroquine-induced hyperpigmentation: the staining pattern. 
  • Hyperthyroidism and lupus-like syndrome in an adolescent treated with minocycline for acne vulgaris. 
  • ICF core sets: how to specify impairment and function in systemic lupus erythematosus. 
  • Identifying Targets for Improving Mental Healthcare of Adolescents with Systemic Lupus Erythematosus: Perspectives from Pediatric Rheumatology Clinicians in the United States and Canada. 
  • IgA-containing circulating immune complexes in dermatitis herpetiformis, Henoch-Schönlein purpura, systemic lupus erythematosus and other diseases. 
  • IgG binding of monoclonal anti-nuclear antibodies from MRL-lpr/lpr mice. 
  • Immune activation by bacterial DNA: a new genetic code. 
  • Immune complexes induce TNF-α and BAFF production from U937 cells by HMGB1 and RAGE. 
  • Immune recognition of DNA in SLE. 
  • Immune response to DNA in systemic lupus erythematosus. 
  • Immune responses to DNA in normal and aberrant immunity. 
  • Immunochemical properties of anti-DNA antibodies in the sera of patients with Escherichia coli bacteremia. 
  • Immunoglobulin GM and KM allotypes in systemic lupus erythematosus. 
  • Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. 
  • Immunological properties of bacterial DNA. 
  • Immunoregulatory aberrations in systemic lupus erythematosus. 
  • Immunoregulatory disorders associated with hereditary angioedema. I. Clinical manifestations of autoimmune disease. 
  • Immunosuppressive/Autoimmune Disorders. 
  • Impact of the revised american academy of ophthalmology guidelines regarding hydroxychloroquine screening on actual practice. 
  • In vitro selection of RNA epitopes using autoimmune patient serum. 
  • Inactive disease and remission in childhood-onset systemic lupus erythematosus. 
  • Independent expression of autoantibodies in systemic lupus erythematosus. 
  • Independently derived murine glomerular immune deposit-forming anti-DNA antibodies are encoded by near-identical VH gene sequences. 
  • Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA. 
  • Infectious mononucleosis patients temporarily recognize a unique, cross-reactive epitope of Epstein-Barr virus nuclear antigen-1. 
  • Influence of assay conditions on ELISA determinations of anti-DNA antibodies. 
  • Inhibition of in vitro NZB antibody responses by cyclosporine. 
  • Intercellular adhesion molecule-1 deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus. 
  • Interleukin-2 receptor expression in peripheral blood lymphocytes from systemic lupus erythematosus patients: relationship to clinical activity. 
  • Introduction: Regulatory B Cell Special Issue-making all the pieces fit. 
  • Is systemic lupus erythematosus, amyotrophic lateral sclerosis, or fibromyalgia associated with Persian Gulf War service? An examination of Department of Defense hospitalization data. 
  • Isolation and analysis of cDNA clones expressing human lupus La antigen. 
  • Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort. 
  • Lack of correlation between serum soluble Fas/APO-1 levels and autoimmune disease. 
  • Large vessel vasculitis of the central nervous system in systemic lupus erythematosus: report and review of the literature. 
  • Late ovarian hyperstimulation syndrome after controlled ovarian stimulation in a woman with systemic lupus erythematosus and lupus nephritis. 
  • Lenalidomide for refractory cutaneous manifestations of pediatric systemic lupus erythematosus. 
  • Long-Term Safety and Efficacy of Epratuzumab in the Treatment of Moderate-to- Severe Systemic Lupus Erythematosus: Results From an Open-Label Extension Study. 
  • Lupus activity in pregnancy. 
  • Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'. 
  • Lupus-related myelitis: serial MR findings. 
  • Lupus-related myelopathy: report of three cases and review of the literature. 
  • Lupus-specific antiribonucleoprotein B cell tolerance in nonautoimmune mice is maintained by differentiation to B-1 and governed by B cell receptor signaling thresholds. 
  • Lymphocytic lymphoma and systemic lupus erythematosus: their coexistence with antibody to the Sm antigen. 
  • Malignancy in Pediatric-onset Systemic Lupus Erythematosus. 
  • Management of dyslipidemia in children and adolescents with systemic lupus erythematosus. 
  • Managing contraception and pregnancy in the rheumatologic diseases. 
  • Massive calcification of the mitral annulus in a 17-year-old patient with juvenile rheumatoid arthritis and systemic lupus erythematosis. 
  • Measurement of fatigue in systemic lupus erythematosus: a systematic review. 
  • Mechanisms of anti-DNA antibody expression in normal and aberrant immunity. 
  • Mechanisms of anti-DNA production in human and murine SLE. 
  • Mechanisms of antinuclear antibody production in the rheumatic diseases. 
  • Mechanisms of autoantibody production in autoimmune MRL mice. 
  • Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome. 
  • Microparticles as a source of extracellular DNA. 
  • Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus. 
  • Microparticles as autoadjuvants in the pathogenesis of SLE. 
  • Microparticles as autoantigens in systemic lupus erythematosus. 
  • Microparticles as autoantigens: making immune complexes big. 
  • Microparticles in the blood of patients with systemic lupus erythematosus (SLE): phenotypic characterization and clinical associations. 
  • Missed opportunities for timely diagnosis of pediatric lupus in South Africa: a qualitative study. 
  • Mixed lymphocyte responses in a four-generation C2 deficiency family. 
  • Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. 
  • Modified Framingham Risk Score predicted 10-y CAD better than the original score in patients with lupus. 
  • Molecular analysis of spontaneous nephrotropic anti-laminin antibodies in an autoimmune MRL-lpr/lpr mouse. 
  • Molecular analysis of the 60-kDa human Ro ribonucleoprotein. 
  • Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies. 
  • Molecular characterization of circulating plasma cells in patients with active systemic lupus erythematosus. 
  • Monocyte receptors for the Fc portion of IgG are increased in systemic lupus erythematosus. 
  • Mortality in primary and secondary myocarditis. 
  • Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo. 
  • Musculoskeletal syndromes associated with malignancy. 
  • Mycophenolate mofetil suppresses autoimmunity and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus. 
  • N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus. 
  • NIH Conference: Immunoglobulin G Fc receptor-mediated clearance in autoimmune diseases. 
  • Necrotizing fasciitis caused by Haemophilus influenzae type E in a 17-year-old girl with systemic lupus erythematosus. 
  • Neurocognitive impairment in children and adolescents with systemic lupus erythematosus. 
  • New Perspectives in Rheumatology: Biomarkers as Entry Criteria for Clinical Trials of New Therapies for Systemic Lupus Erythematosus: The Example of Antinuclear Antibodies and Anti-DNA. 
  • Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans. 
  • Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States. 
  • Occupational risk factors for the development of systemic lupus erythematosus. 
  • Paediatric rheumatic disease: lessons from SLE: children are not little adults. 
  • Panniculitis in lupus erythematosus. 
  • Pathogenesis of pregnancy complications in systemic lupus erythematosus. 
  • Patients with antiphospholipid antibodies: CT and MR findings of the brain. 
  • Patterns of autoantibody expression in pediatric and adult systemic lupus erythematosus. 
  • Patterns of heavy and light chain utilization in the antibody response to single-stranded bacterial DNA in normal human subjects and patients with systemic lupus erythematosus. 
  • Pediatric biopsy of a single native kidney. 
  • Perceived stress and reported cognitive symptoms among Georgia patients with systemic lupus erythematosus. 
  • Perinatal outcomes in women with systemic lupus erythematosus. 
  • Polypoidal choroidal vasculopathy and systemic lupus erythematosus. 
  • Polyspecific binding of Escherichia coli beta-galactosidase by murine antibodies to DNA. 
  • Polyspecific reactivity of a murine monoclonal antibody that binds to nuclear matrix-associated, chromatin-bound autoantigens. 
  • Power in numbers. 
  • Predictors of preterm birth in patients with mild systemic lupus erythematosus. 
  • Preliminary core sets of measures for disease activity and damage assessment in juvenile systemic lupus erythematosus and juvenile dermatomyositis. 
  • Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus. 
  • Premature atherosclerosis in pediatric systemic lupus erythematosus: risk factors for increased carotid intima-media thickness in the atherosclerosis prevention in pediatric lupus erythematosus cohort. 
  • Prevalence of congenital or acquired complement deficiency in patients with sporadic meningococcal disease. 
  • Progressive multifocal leukoencephalopathy in patients with systemic lupus erythematosus: a systematic literature review. 
  • Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice. 
  • Provider perceptions on the management of lupus during pregnancy: barriers to improved care. 
  • Pseudomonas septicemia with nodules and bullae. 
  • Pulmonary hemorrhage and systemic lupus erythematosus. 
  • Pulmonary hemorrhage in pediatric patients with systemic lupus erythematosus. 
  • Quantitative genetic variation in CD19 expression correlates with autoimmunity. 
  • Racial and Ethnic Disparities in the Pregnancies of Women With Systemic Lupus Erythematosus. 
  • Randomised trial of plasma exchange in mild systemic lupus erythematosus. 
  • Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus. 
  • Rapid clinical progression to diagnosis among African-American men with systemic lupus erythematosus. 
  • Reasons for cesarean and medically indicated deliveries in pregnancies in women with systemic lupus erythematosus. 
  • Regular examinations for toxic maculopathy in long-term chloroquine or hydroxychloroquine users. 
  • Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice. 
  • Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies. 
  • Relevance of systemic lupus erythematosus nephritis animal models to human disease. 
  • Relevant concepts of functioning for patients with systemic lupus erythematosus identified in a Delphi exercise of experts and a literature review. 
  • Renal biopsy in patients with systemic lupus erythematosus: Not just lupus glomerulonephritis! 
  • Reply: To PMID 22505314. 
  • Results of free vascularized fibular grafting for femoral head osteonecrosis in patients with systemic lupus erythematosus. 
  • Retinal nerve fibre layer thickness measurements in patients using chloroquine. 
  • Retinal venular calibre is increased in patients with autoimmune rheumatic disease: a case-control study. 
  • Rheumatologic manifestations of cancer. 
  • Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides. 
  • Risk factors for development of systemic lupus erythematosus: allergies, infections, and family history. 
  • Risk factors for renal allograft loss in patients with systemic lupus erythematosus. 
  • Risk of venous thromboembolism occurrence among adults with selected autoimmune diseases: a study among a U.S. cohort of commercial insurance enrollees. 
  • Role of tumor necrosis factor alpha and potential benefit of tumor necrosis factor blockade treatment in systemic lupus erythematosus: comment on the editorial by Pisetsky. 
  • Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of SBI-087, a CD20-Directed B-cell Depleting Agent: Phase 1 Dose Escalating Studies in Patients With Either Mild Rheumatoid Arthritis or Systemic Lupus. 
  • Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein. 
  • Selective small antigenic structures are capable of inducing widespread autoimmunity which closely mimics the humoral fine specificity of human SLE. 
  • Self-efficacy and pain catastrophizing in systemic lupus erythematosus: relationship to pain, stiffness, fatigue, and psychological distress. 
  • Serum immunoglobulin levels in systemic lupus erythematosus: the effects of age, sex, race and disease duration. 
  • Severe disease presentation and poor outcomes among pediatric systemic lupus erythematosus patients in South Africa. 
  • Similar CD19 dysregulation in two autoantibody-associated autoimmune diseases suggests a shared mechanism of B-cell tolerance loss. 
  • Sjögren's syndrome (Sicca syndrome): current issues. 
  • Smoking and use of hair treatments in relation to risk of developing systemic lupus erythematosus. 
  • Sociodemographic associations with early disease damage in patients with systemic lupus erythematosus. 
  • Specificity analysis of antibodies to single-stranded micrococcal DNA in the sera of normal human subjects and patients with systemic lupus erythematosus. 
  • Specificity and immunochemical properties of anti-DNA antibodies induced in normal mice by immunization with mammalian DNA with a CpG oligonucleotide as adjuvant. 
  • Specificity and immunochemical properties of antibodies to bacterial DNA in sera of normal human subjects and patients with systemic lupus erythematosus (SLE). 
  • Specificity and immunochemical properties of antibodies to bacterial DNA. 
  • Specificity of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. 
  • Specificity of antibodies to bacterial DNA in the sera of healthy human subjects and patients with systemic lupus erythematosus. 
  • Spontaneous expression of antibodies to DNA of various species origin in sera of normal subjects and patients with systemic lupus erythematosus. 
  • Spontaneous formation of germinal centers in autoimmune mice. 
  • Standardization of anti-DNA antibody assays. 
  • State of the art: Reproduction and pregnancy in rheumatic diseases. 
  • Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response. 
  • Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse. 
  • Survival in systemic lupus erythematosus. A multivariate analysis of demographic factors. 
  • Systemic lupus erythematosus and HIV infection: a whimsical relationship. Reports of two cases and review of the literature. 
  • Systemic lupus erythematosus and discoid lupus erythematosus. 
  • Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States. 
  • Systemic lupus erythematosus and pregnancy outcomes: an update and review of the literature. 
  • Systemic lupus erythematosus and related diseases. 
  • Systemic lupus erythematosus in three ethnic groups. IV. Factors associated with self-reported functional outcome in a large cohort study. LUMINA Study Group. Lupus in Minority Populations, Nature versus Nurture. 
  • Systemic lupus erythematosus in three ethnic groups: II. Features predictive of disease activity early in its course. LUMINA Study Group. Lupus in minority populations, nature versus nurture. 
  • Systemic lupus erythematosus. 
  • Systemic lupus erythematosus. 
  • Systemic lupus erythematosus. Diagnosis and treatment. 
  • Systemic lupus erythematosus: a matter of life and death. 
  • T-cell-mediated pure red-cell aplasia in systemic lupus erythematosus: response to cyclosporin A and mycophenolate mofetil. 
  • Terminal complement complexes (SC5b-9) in cerebrospinal fluid in autoimmune nervous system diseases. 
  • The 1978 annual meeting of the American Rheumatism Association. 
  • The 8.5-kb PstI allele of the stress protein gene, Hsp70-2: an independent risk factor for systemic lupus erythematosus in African Americans? 
  • The American College of Rheumatology response criteria for systemic lupus erythematosus clinical trials: measures of overall disease activity. 
  • The LE cell: crime scene or crime stopper? 
  • The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link? 
  • The SLE-key test serological signature: new insights into the course of lupus. 
  • The antigenic properties of bacterial DNA in normal and aberrant immunity. 
  • The binding of anti-DNA antibodies to phosphorothioate oligonucleotides in a solid phase immunoassay. 
  • The binding of sera of patients with SLE to bacterial and mammalian DNA. 
  • The blood nucleome in the pathogenesis of SLE. 
  • The butterfly rash of lupus: an example of aposematism? 
  • The clinical utility of measuring complement and anti-dsDNA antibodies during pregnancy in patients with systemic lupus erythematosus. 
  • The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. 
  • The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge. 
  • The dichotomous role of nitric oxide in the pathogenesis of accelerated atherosclerosis associated with systemic lupus erythematosus. 
  • The effect of UVB on lupus skin: new light on the role of apoptosis in the pathogenesis of autoimmunity. 
  • The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects. 
  • The evolving role of blood and marrow transplantation for the treatment of autoimmune diseases. 
  • The expression of plasma nucleosomes in mice undergoing in vivo apoptosis. 
  • The fourth component of complement in the cerebrospinal fluid in systemic Lupus erythematosus. 
  • The generation of extracellular DNA in SLE: the role of death and sex. 
  • The genetics of autoantibody production in MRL/lpr lupus mice. 
  • The health education for lupus study: a randomized controlled cognitive-behavioral intervention targeting psychosocial adjustment and quality of life in adolescent females with systemic lupus erythematosus. 
  • The immune response to cell death in SLE. 
  • The immunologic properties of DNA. 
  • The impact of cyclophosphamide on menstruation and pregnancy in women with rheumatologic disease. 
  • The impact of increased lupus activity on obstetric outcomes. 
  • The influence of DNA size on the binding of anti-DNA antibodies in the solid and fluid phase. 
  • The influence of DNA size on the binding of antibodies to DNA in the sera of normal human subjects and patients with systemic lupus erythematosus (SLE). 
  • The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers. 
  • The leader RNA of vesicular stomatitis virus is bound by a cellular protein reactive with anti-La lupus antibodies. 
  • The management of pediatric systemic lupus erythematosus. 
  • The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosus. 
  • The prevention, screening and treatment of congenital heart block from neonatal lupus: a survey of provider practices. 
  • The relationship between soluble interleukin 2 receptor levels and antidouble stranded DNA antibody levels in patients with systemic lupus erythematosus. 
  • The relationship of anticardiolipin antibodies to disease manifestations in pediatric systemic lupus erythematosus. 
  • The relationship of complement to allergic disease. 
  • The role of Epstein-Barr virus in systemic lupus erythematosus. 
  • The role of bacterial DNA in autoantibody induction. 
  • The role of extracellular DNA in autoimmunity in SLE. 
  • The role of innate immunity in the induction of autoimmunity. 
  • The role of microparticles in the generation of immune complexes in murine lupus. 
  • The role of microparticles in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus. 
  • The rs4774 CIITA missense variant is associated with risk of systemic lupus erythematosus. 
  • The use of fluorometric assays to assess the immune response to DNA in murine systemic lupus erythematosus. 
  • Therapeutic CD154 antibody for lupus: promise for the future? 
  • Therapy Insight: cardiovascular disease in pediatric systemic lupus erythematosus. 
  • Thrombosis and the antiphospholipid syndrome. 
  • Total lymphoid irradiation as an immunosuppressive agent for transplantation and the treatment of 'autoimmune' disease: a review. 
  • Toward the development of criteria for global flares in juvenile systemic lupus erythematosus. 
  • Transancestral mapping and genetic load in systemic lupus erythematosus. 
  • Treatment of an acquired Factor XIII inhibitor in an adolescent with systemic lupus erythematosus and renal failure. 
  • Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus. 
  • Urine macrophage migration inhibitory factor in pediatric systemic lupus erythematosus. 
  • Use of atorvastatin in systemic lupus erythematosus in children and adolescents. 
  • V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice. 
  • VH gene analysis of spontaneously activated B cells in adult MRL-lpr/lpr mice. J558 bias is not limited to classic lupus autoantibodies. 
  • Validation of Patient-Reported Outcomes Measurement Information System Short Forms for Use in Childhood-Onset Systemic Lupus Erythematosus. 
  • Vibrio fetus endocarditis in a patient with systemic lupus erythematosus. 
  • Will studies in individuals with systemic lupus erythematosus be the key to future HIV vaccine design? 
  • [Collagen diseases]. 
  • [Finding of so-called L E cells in a pneumonitis focus before death from acute lupus erythematosus]. 
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  Keywords of People

  • Allen, Nancy Bates, Professor of Medicine, Medicine, Rheumatology and Immunology
  • Dement, John McCray, Professor Emeritus in Family Medicine and Community Health, Family Medicine & Community Health,Occupational & Environmental Medicine
  • Kelsoe, Garnett H., James B. Duke Professor of Immunology, Immunology
  • Muir, Kelly Walton, Associate Professor of Ophthalmology, Ophthalmology, Glaucoma