Lymphokines

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  Subject Areas on Research

  • A novel polypeptide secreted by activated human T lymphocytes. 
  • Abnormalities of chemotactic lymphokine synthesis and mononuclear leukocyte chemotaxis in Wiskott-Aldrich syndrome. 
  • Acute graft-vs-host disease: pathobiology and management. 
  • Adaptive mechanisms that preserve cardiac function in mice without myoglobin. 
  • Adenoviral-mediated gene transfer induces sustained pericardial VEGF expression in dogs: effect on myocardial angiogenesis. 
  • Aged human muscle demonstrates an altered gene expression profile consistent with an impaired response to exercise. 
  • Altered cell-averaged microviscosity of murine peritoneal macrophages undergoing activation in vivo or in vitro. 
  • Ameroid constrictor versus hydraulic occluder: creation of hibernating myocardium. 
  • Angiogenic growth factors in the pathophysiology of a murine model of acute lung injury. 
  • Angiogenic potential of perivascularly delivered aFGF in a porcine model of chronic myocardial ischemia. 
  • Angiokines Associated with Targeted Therapy Outcomes in Patients with Non-Clear Cell Renal Cell Carcinoma. 
  • Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. 
  • Characterization of human chemotactic lymphokine production induced by mitogens and mixed leukocyte reactions using a new microassay. 
  • Chemotactically responsive and nonresposive forms of a continuous human monocyte cell line. 
  • Combined immunodeficiency due to the selective absence of CD4 inducer T lymphocytes. 
  • Comparative effects of basic fibroblast growth factor and vascular endothelial growth factor on coronary collateral development and the arterial response to injury. 
  • Complete reversal of ischemic wall motion abnormalities by combined use of gene therapy with transmyocardial laser revascularization. 
  • Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma. 
  • Cutaneous lesions of secondary syphilis are highly angiogenic. 
  • Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. 
  • Development of specific receptors for N-formylated chemotactic peptides in a human monocyte cell line stimulated with lymphokines. 
  • Different effects of glucose starvation on expression and stability of VEGF mRNA isoforms in murine ovarian cancer cells. 
  • Differential expression of VEGF isoforms in mouse during development and in the adult. 
  • Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis. 
  • Direct myocardial revascularization and angiogenesis--how many patients might be eligible? 
  • Do humoral factors mediate cancer chemotherapy-induced emesis? 
  • Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling. 
  • Early wound healing exhibits cytokine surge without evidence of hypoxia. 
  • Ectopic expression of transcription factor NF-E2 alters the phenotype of erythroid and monoblastoid cells. 
  • Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture. 
  • Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. 
  • Effect of ionizing radiation on thymidine uptake, differentiation, and VEGFR2 receptor expression in endothelial cells: the role of VEGF(165). 
  • Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts. 
  • Efficacy of intracoronary or intravenous VEGF165 in a pig model of chronic myocardial ischemia. 
  • Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor. 
  • Engineering DNA vaccines via co-delivery of co-stimulatory molecule genes. 
  • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. 
  • Evaluation of lymphocyte differentiation in primary and secondary immunodeficiency diseases. 
  • Expression of differentiation antigens by hybrids of human lymphoblastoid cells. 
  • Expression of endocrine gland-derived vascular endothelial growth factor in ovarian carcinoma. 
  • Gene therapy and genomic strategies for cardiovascular surgery: The emerging field of surgiomics. 
  • Generalized microsporum audoninii infection and depressed cellular immunity associated with a missing plasma factor required for lymphocyte blastogenesis. 
  • Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma. 
  • Generation of melanoma-specific, cytotoxic CD4(+) T helper 2 cells: requirement of both HLA-DR15 and Fas antigens on melanomas for their lysis by Th2 cells. 
  • Genetic basis of murine responses to hyperoxia-induced lung injury. 
  • Genetic targeting for cardiovascular therapeutics: are we near the summit or just beginning the climb? 
  • HCPTPA, a protein tyrosine phosphatase that regulates vascular endothelial growth factor receptor-mediated signal transduction and biological activity. 
  • Healing of a free tracheal autograft is enhanced by topical vascular endothelial growth factor in an experimental rabbit model. 
  • Histopathology and vascular endothelial growth factor in untreated and diode laser-treated retinopathy of prematurity. 
  • Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations. 
  • Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor. 
  • Immune responses of human lymphocytes in vitro. 
  • Immunological mechanisms of periodontal tissue destruction. 
  • Implications of leukoregulin to autologous tumor-specific human T-cell populations. 
  • In vitro modulation of macrophage tumoricidal activity: partial characterization of a macrophage-activating factor(s) in supernatants of NaIO4-treated peritoneal cells. 
  • Induction and maintenance of increased VEGF protein by chronic motor nerve stimulation in skeletal muscle. 
  • Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. 
  • Inhibition of vascular endothelial growth factor in the treatment of colorectal cancer. 
  • Interleukin 2 produced by activated B lymphocytes acts as an autocrine proliferation-inducing lymphokine. 
  • Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy. 
  • Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. 
  • Long- and short-term effects of biological hydrogels on capsule microvascular density around implants in rats. 
  • Macrophage tumor killing: influence of the local environment. 
  • Macrophage-mediated fungistasis: requirement for a macromolecular component in serum. 
  • Modulation of the tumoricidal function of activated macrophages by bacterial endotoxin and mammalian macrophage activation factor (s). 
  • Molecular and cellular mechanisms of leukocyte chemotaxis. 
  • Molecular composition of an antigen-specific, Ly-1 T suppressor inducer factor. One molecule binds antigen and is I-J-; another is I-J+, does not bind antigen, and imparts an Igh-variable region-linked restriction. 
  • PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects. 
  • Phagocytic cells synthesize 19-nor-10-keto-25-hydroxyvitamin D3, a metabolite that may induce differentiation of the human monoblastic cell line U937. 
  • Phase I study of intraperitoneal recombinant human interleukin 12 in patients with Müllerian carcinoma, gastrointestinal primary malignancies, and mesothelioma. 
  • Phase I study of recombinant human endostatin in patients with advanced solid tumors. 
  • Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity. 
  • Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. 
  • Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage. 
  • Preexposure of resting B cells to interferon-gamma enhances their proliferative response to subsequent activation signals. 
  • Preparation and characterization of lymphocyte-activating factor (LAF) from acute monocytic and myelomonocytic leukemia cells. 
  • Production of chemotactic factor and lymphotoxin by human leukocytes stimulated with Herpes simplex virus. 
  • Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. 
  • Promotion of the development of enteric neurons and glia by neuropoietic cytokines: interactions with neurotrophin-3. 
  • Protection from death in endotoxin shock: does fish oil need a LIF? 
  • Quantitation and physiological characterization of angiogenic vessels in mice: effect of basic fibroblast growth factor, vascular endothelial growth factor/vascular permeability factor, and host microenvironment. 
  • Radiation-induced hypoxia may perpetuate late normal tissue injury. 
  • Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. 
  • Reduction of human prostate tumor vascularity by the alpha1-adrenoceptor antagonist terazosin. 
  • Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. 
  • Renal allograft-infiltrating lymphocytes. A prospective analysis of in vitro growth characteristics and clinical relevance. 
  • Serum vascular endothelial growth factor as a surveillance marker for cellular rejection in pediatric cardiac transplantation. 
  • Serum vascular endothelial growth factor is elevated in cystic fibrosis and decreases with treatment of acute pulmonary exacerbation. 
  • Serum vascular endothelial growth factor is elevated in cystic fibrosis and decreases with treatment of acute pulmonary exacerbation. 
  • Serum von Willebrand factor, matrix metalloproteinase-9, and vascular endothelial growth factor levels predict the onset of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 
  • Some fixation reagents reduce or abolish the detectability of Ia-antigen and HLA-DR on cells. 
  • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. 
  • Synergy between tumor immunotherapy and antiangiogenic therapy. 
  • TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity. 
  • Technology evaluation: VEGF165 gene therapy, Valentis Inc. 
  • The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. 
  • The conformation-dependent interaction of alpha 2-macroglobulin with vascular endothelial growth factor. A novel mechanism of alpha 2-macroglobulin/growth factor binding. 
  • The human myoepithelial cell displays a multifaceted anti-angiogenic phenotype. 
  • The role of functionally distinct helper T lymphocyte subpopulations in the induction of human B cell differentiation. 
  • The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression. 
  • The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer. 
  • Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate. 
  • Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. 
  • Topical VEGF enhances healing of thoracic aortic anastomosis for coarctation in a rabbit model. 
  • Transduction of human melanoma cells with the gamma interferon gene enhances cellular immunity. 
  • Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells. 
  • Use of SMART-generated cDNA for gene expression studies in multiple human tumors. 
  • VEGF increases retinal vascular ICAM-1 expression in vivo. 
  • VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases. 
  • Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study. 
  • Vascular endothelial growth factor expression in pig latissimus dorsi myocutaneous flaps after ischemia reperfusion injury. 
  • Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide. 
  • Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades. 
  • Vascular endothelial growth factor up-regulates cyclooxygenase-2 expression in human endothelial cells. 
  • [A novel model for visualization of tumor cell-induced angiogenesis in vivo]. 
  • [Inhibitation of tumor angiogenesis, growth and metastasis by blocking VEGF paracrine pathway]. 
  • p53 does not repress hypoxia-induced transcription of the vascular endothelial growth factor gene. 
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  Keywords of People

  • Halabi, Susan, Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology